Isotretinoin Plus Interferon in Treating Patients With Recurrent Cancer
NCT00002506 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL
Last updated 2011-05-12
Summary
RATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent the development or recurrence of cancer. The use of isotretinoin may be an effective way to prevent cancer or stop cancer from growing. Interferon alfa may interfere with the growth of cancer cells. Combining isotretinoin and interferon may be an effective treatment for some recurrent cancers.
PURPOSE: Phase II trial to study the effectiveness of interferon alfa plus isotretinoin in treating patients with recurrent cancer.
Conditions
- Cervical Cancer
- Esophageal Cancer
- Head and Neck Cancer
- Lung Cancer
- Non-melanomatous Skin Cancer
- Penile Cancer
Interventions
- BIOLOGICAL
-
recombinant interferon alfa
- DRUG
-
isotretinoin
Sponsors & Collaborators
-
Cancer Biotherapy Research Group
collaborator OTHER -
Hoag Memorial Hospital Presbyterian
lead OTHER
Principal Investigators
-
Robert O. Dillman, MD, FACP · Cancer Biotherapy Research Group
Study Design
- Purpose
- TREATMENT
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1992-08-31
- Primary Completion
- 1996-01-31
- Completion
- 1999-02-28
Countries
- United States
Study Locations
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