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Effect of Systemic Isotretinoin on Serum Irisin Level in Acne Vulgaris Patients

NCT05869188 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 60

Last updated 2024-12-09

No results posted yet for this study

Summary

Acne vulgaris is a chronic inflammatory skin disease affecting the pilosebaceous unit. It is clinically characterized by comedones, papules, pustules, nodules, cysts and scarring on the face and trunk.

The severity of the disease ranges from mild comedonal acne to severe nodulocystic acne which can be permanently disfiguring.In addition to the physical lesions, the disease can have a profound psychologic impact, contributing to low self-esteem, depression and anxiety.In addition to the physical lesions, the disease can have a profound psychologic impact, contributing to low self-esteem, depression and anxiety.

Conditions

  • Acne Vulgaris

Interventions

DRUG

Isotretinoin

* Evaluate serum irisin level in acne vulgaris and compare it with healthy control . * Evaluate the effect of systemic isotretinoin on serum irisin in acne vulgaris patients .

Sponsors & Collaborators

  • South Valley University

    lead OTHER

Principal Investigators

  • Essra Abass, Lecturer · Clinical Pathology Department, Faculty of Medicine, South valley University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
14 Years
Max Age
40 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-06-01
Primary Completion
2023-12-15
Completion
2024-01-01

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05869188 on ClinicalTrials.gov