MedTrace Logo

Comparison Between Isotretinoin, Silymarin and Both in the Treatment of Acne Vulgaris

NCT05666765 · Status: UNKNOWN · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 75

Last updated 2022-12-28

No results posted yet for this study

Summary

This study aims to compare the effects of isotretinoin and silymarin or both in treatment of acne and their effects on the level of IGF-1, SAA1 and malondialdehyde (MDA) in acne patients.

Conditions

  • Acne Vulgaris

Interventions

DRUG

Isotretinoin ,silymarin

20mg/day isotretinoin for 3 months. 140 mg/day silymarin for 3 months. 20mg/day isotretinoin and 140mg/day silymarin for 3 months.

Sponsors & Collaborators

  • Tanta University

    lead OTHER

Principal Investigators

  • Ghada F Hassan, A.professor · Tanta University

  • Dalia R Elafify, Doctor · Tanta University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
16 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-01-01
Primary Completion
2023-11-01
Completion
2024-01-01

Countries

  • Egypt

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05666765 on ClinicalTrials.gov