Treatment of Mild Hypertension Study (TOMHS)
NCT00000522 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL
Last updated 2016-02-25
Summary
To compare the effects of nonpharmacologic therapy alone with those of one of five active drug regimens combined with non-pharmacologic therapy, for long- term management of patients with mild hypertension.
Conditions
- Cardiovascular Diseases
- Heart Diseases
- Hypertension
- Vascular Diseases
Interventions
- BEHAVIORAL
-
diet, sodium-restricted
- BEHAVIORAL
-
diet, reducing
- BEHAVIORAL
-
exercise
- BEHAVIORAL
-
alcohol restriction
- DRUG
-
chlorthalidone
- DRUG
-
acebutolol
- DRUG
-
doxazosin
- DRUG
-
amlodipine
- DRUG
-
enalapril
Sponsors & Collaborators
-
National Heart, Lung, and Blood Institute (NHLBI)
collaborator NIH - lead OTHER
Principal Investigators
-
Richard Grimm · University of Minnesota
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
Eligibility
- Min Age
- 45 Years
- Max Age
- 69 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1985-08-31
- Completion
- 1994-05-31
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