Trial of Antihypertensive Intervention Management
NCT00000513 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL
Last updated 2013-11-26
Summary
The objective of the Trial of Antihypertensive Intervention Management (TAIM) was to determine the efficacy of dietary management and/or drug therapy, namely thiazide-like diuretics or a beta-blocker, in the control of mild hypertension. Additionally, the Continuation of the Trial of Antihypertensive Intervention Management (COTAIM) tested the effects of long-term weight reduction, and sodium/potassium changes added to weight reduction, as well as the original drug treatment, on the failure rate of blood pressure control.
Conditions
- Cardiovascular Diseases
- Heart Diseases
- Hypertension
- Vascular Diseases
Interventions
- BEHAVIORAL
-
diet, reducing
- BEHAVIORAL
-
diet, sodium-restricted
- DRUG
-
chlorthalidone
- DRUG
-
atenolol
Sponsors & Collaborators
-
National Heart, Lung, and Blood Institute (NHLBI)
lead NIH
Principal Investigators
-
Morton Blaufox · Albert Einstein College of Medicine
-
Kent Kirchner · University of Mississippi Medical Center
-
Albert Oberman · University of Alabama at Birmingham
-
Sylvia Wassertheil-Smoller · Albert Einstein College of Medicine
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
Eligibility
- Min Age
- 21 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1984-04-30
- Completion
- 1994-11-30
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