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Treatment of Hypertension In Adults With ThiaZIDES: Pragmatic Trial Pilot Study

NCT02591628 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 2027

Last updated 2017-10-11

No results posted yet for this study

Summary

This proposed pilot study will test methods and feasibility for a large pragmatic clinical trial comparing two inexpensive, first-line drugs for treating high blood pressure to determine if one is superior in preventing serious cardiovascular events and death. It will develop and test novel approaches to conducting trials that will be faster, less expensive, and more realistic by being embedded in a typical practice setting and using advanced health information technology.

Conditions

Interventions

BEHAVIORAL

HCTZ prescription conversion to chlorthalidone

The intervention is simply a prescription conversion and the main outcome is whether or not patients accept the conversion and treatment with chlorthalidone.

Sponsors & Collaborators

  • Kaiser Permanente

    collaborator OTHER

  • HealthPartners Institute

    lead OTHER

Principal Investigators

  • Karen L Margolis, MD, MPH · HealthPartners Institute

  • Stephen P Fortmann, MD · Kaiser Permanente

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2015-08-31
Primary Completion
2017-07-31
Completion
2017-07-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02591628 on ClinicalTrials.gov