Methamphetamine

Drug

Also known as: crystal methamphetamine, meth

Drug Profile

Methamphetamine is a central nervous system stimulant with prescription and nonmedical use contexts. In the United States, prescription products containing methamphetamine are marketed (e.g., Desoxyn) for limited clinical indications. It also has high abuse/addiction risk in nonmedical settings.

Drug Class
CNS stimulant (serotonin-norepinephrine-dopamine releasing agent)
Approval Status
Prescription products are available in the U.S.; controlled as Schedule II in the U.S.
Mechanism of Action
Acts as a serotonin-norepinephrine-dopamine releasing agent and CNS stimulant.
Brand Names
  • Desoxyn
  • \Desoxyn Gradumet\
Indications
  • ADHD
  • \Weight loss (obesity/overweight)\

Related News

Multiple Arrests in Oklahoma and California Drug Investigations

Law enforcement in Oklahoma and California have reported results from separate drug investigations, leading to multiple arrests and seizures. The Oklahoma case involved a nearly two-year undercover operation resulting in 20 people charged across 66 criminal cases related to methamphetamine and fentanyl. California authorities arrested several suspects and seized significant quantities of fentanyl and methamphetamine in two distinct investigations.

Multiple Drug Busts in NC and TN Lead to Over 30 Arrests

Two major drug trafficking investigations in North Carolina and Tennessee have led to over 30 arrests combined. The North Carolina case resulted in more than 170 charges after seizing cocaine, fentanyl, methamphetamine, guns and cash. In Tennessee, 15 individuals were indicted for conspiring to distribute cocaine, with seizures including fentanyl, marijuana, cocaine, methamphetamine, firearms and cash.

Multiple Drug Busts Lead to Arrests in Virginia and Alabama

Three recent drug enforcement operations in Virginia and Alabama led to multiple arrests and seizures of cocaine, fentanyl, methamphetamine, firearms, and over $3,000 in cash. The cases involved separate investigations by county sheriff's offices and drug task forces.

Vancouver Police Seize Over $79K in Drugs, Cash in 'Project Bingo' Investigation

Vancouver police seized over $79,000 in illicit drugs, cash, and weapons during a six-month investigation called "Project Bingo" targeting drug trafficking on the Downtown Eastside. The search uncovered fentanyl, cocaine, methamphetamine, dilaudid pills, illegal cigarettes, and a large cache of weapons. A 61-year-old man was arrested and released pending further investigation.

Ohio prison drug-smuggling case highlights spread of K2 paper

Drug-soaked paper has become the most commonly found drug in Ohio prisons and was tied to at least 13 fatal K2 overdoses in 2024. Convictions in the state’s largest prison drug conspiracy case detailed how the paper was smuggled and sold.

Major Drug Busts in New Zealand and Canada Seize Cocaine, Meth, Fentanyl

New Zealand police arrested 11 people and seized drugs, cash, and firearms after uncovering a dark web drug import network, while Canadian police made a separate bust seizing cocaine, fentanyl, and methamphetamine. The New Zealand operation involved international cooperation and intercepted over 200kg of drugs at borders. The busts come as New Zealand data shows record-breaking cocaine consumption nationwide.

Months-Long Investigation Leads to Multiple Drug Trafficking Arrests and Seizures

A months-long drug investigation in North Carolina led to four arrests and over 70 felony charges, with seizures including firearms and 120 grams of cocaine and methamphetamine. Separately, a traffic stop revealed cocaine, marijuana, and a firearm, highlighting ongoing regional drug activity. Law enforcement officials note challenges from differing state marijuana laws and increasing drug-related incidents.

Related Clinical Trials

NCT ID Title Status Phase
NCT06989853

Methamphetamine and Troriluzole

RECRUITING EARLY_PHASE1
NCT06721494

A Single-Dose Study to Evaluate Safety and Efficacy of CS-1103 in Participants Receiving a Single Dose of Methamphetamine

RECRUITING PHASE2
NCT05783817

MDMA-Assisted CBT for OCD (MDMA-CBT4OCD Study)

RECRUITING PHASE2
NCT05379959

Effects of Stimulants on Behavioral and Neural Markers of Social Motivation, Ability, and Neural Markers of Social Function

COMPLETED EARLY_PHASE1
NCT05003076

Brain Function and EEG

COMPLETED EARLY_PHASE1
NCT04642820

Drugs Brain and Behavior (DDP)

COMPLETED EARLY_PHASE1
NCT04614584

Mirtazapine and Methamphetamine Drug-drug Interaction Study

COMPLETED PHASE1
NCT04178993

Behavioral Effects of Drugs (Inpatient): 40 [Methamphetamine, Methylphenidate, Duloxetine]

COMPLETED PHASE1
NCT03790618

Effect of Stimulant Drugs on Social Perception

COMPLETED PHASE1
NCT03106571

Study of Pomaglumetad and Methamphetamine

TERMINATED PHASE1