Methamphetamine

Drug

Also known as: crystal methamphetamine, meth, Meth

Drug Profile

Methamphetamine is a central nervous system stimulant with prescription and nonmedical use contexts. In the United States, prescription products containing methamphetamine are marketed (e.g., Desoxyn) for limited clinical indications. It also has high abuse/addiction risk in nonmedical settings.

Drug Class
CNS stimulant (serotonin-norepinephrine-dopamine releasing agent)
Approval Status
Prescription products are available in the U.S.; controlled as Schedule II in the U.S.
Mechanism of Action
Acts as a serotonin-norepinephrine-dopamine releasing agent and CNS stimulant.
Brand Names
  • Desoxyn
  • \Desoxyn Gradumet\
Indications
  • ADHD
  • \Weight loss (obesity/overweight)\

Related News

Two Arrested on Drug Charges After Traffic Stops in Kentucky and Missouri

Two traffic stops in Kentucky and Missouri resulted in drug charges. In Greenup County, a half-pound of suspected methamphetamine was found, leading to charges against two individuals. In Miller County, 28.9 grams of methamphetamine were discovered, and two people face felony delivery charges.

Federal Recidivist and Pennsylvania Woman Plead Guilty to Drug Trafficking

A Florida recidivist with a prior federal drug conviction and a Pennsylvania woman pleaded guilty to separate drug trafficking charges involving crack cocaine, methamphetamine, and synthetic cannabinoids. The Florida defendant faces at least 10 years to life, with sentencing set for September 3, 2026.

Related Clinical Trials

NCT ID Title Status Phase
NCT06989853

Methamphetamine and Troriluzole

RECRUITING EARLY_PHASE1
NCT06721494

A Single-Dose Study to Evaluate Safety and Efficacy of CS-1103 in Participants Receiving a Single Dose of Methamphetamine

RECRUITING PHASE2
NCT05783817

MDMA-Assisted CBT for OCD (MDMA-CBT4OCD Study)

RECRUITING PHASE2
NCT05379959

Effects of Stimulants on Behavioral and Neural Markers of Social Motivation, Ability, and Neural Markers of Social Function

COMPLETED EARLY_PHASE1
NCT05003076

Brain Function and EEG

COMPLETED EARLY_PHASE1
NCT04642820

Drugs Brain and Behavior (DDP)

COMPLETED EARLY_PHASE1
NCT04614584

Mirtazapine and Methamphetamine Drug-drug Interaction Study

COMPLETED PHASE1
NCT04178993

Behavioral Effects of Drugs (Inpatient): 40 [Methamphetamine, Methylphenidate, Duloxetine]

COMPLETED PHASE1
NCT03790618

Effect of Stimulant Drugs on Social Perception

COMPLETED PHASE1
NCT03106571

Study of Pomaglumetad and Methamphetamine

TERMINATED PHASE1