Clinical Trials Updated in 2026

NCT05921487 | ACTIVE_NOT_RECRUITING | NA

15 participants

Time Restricted Eating to Mitigate Obesity in Veterans With Spinal Cord Injury

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2023-09-01
Completion:: 2026-07-01

Conditions

Spinal Cord Injury
Obesity

Interventions

BEHAVIORAL

No Results Yet

NCT05918640 | RECRUITING | PHASE1/PHASE2

63 participants

Lurbinectedin in FET-Fused Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2023-07-27
Completion:: 2028-07-30

Conditions

Ewing Sarcoma
Desmoplastic Small Round Cell Tumor
Pediatric Cancer
Undifferentiated Sarcoma

Interventions

DRUG

No Results Yet

NCT05911568 | RECRUITING

1060 participants

Treatment With Endovascular Intervention for STroke Patients With Existing Disability

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-02
Start Date:: 2023-11-16
Completion:: 2028-01-15

Conditions

Stroke
Stroke, Acute
Stroke, Ischemic

Interventions

PROCEDURE
OTHER

No Results Yet

NCT05907343 | RECRUITING | NA

180 participants

Closed-Loop Brain Stimulation as a Potential Intervention for Cognitive Decline

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2023-05-31
Completion:: 2027-10-31

Conditions

Mild Cognitive Impairment
Alzheimer Dementia (AD)

Interventions

DEVICE

No Results Yet

NCT05900882 | COMPLETED | PHASE2

29 participants

SVRd for the Treatment of Newly Diagnosed Multiple Myeloma Patients Presenting With Extramedullary Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2022-07-15
Completion:: 2026-08-30

Conditions

Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT05895162 | COMPLETED | NA

64 participants

Zinc-containing Vaginal Gel and Oral Fluconazole for Vulvovaginal Candidiasis.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2023-06-10
Completion:: 2026-04-20

Conditions

Vulvovaginal Candidiasis
Vaginal Yeast Infections

Interventions

DRUG

No Results Yet

NCT05889520 | COMPLETED

300 participants

The UFIM (Ultraprocessed Foods In Breast Milk) Project

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-02
Start Date:: 2023-05-23
Completion:: 2026-05-23

Conditions

Child Malnutrition
Child Allergy
Maternal Exposure

No Results Yet

NCT05883748 | ENROLLING_BY_INVITATION | PHASE2/PHASE3

230 participants

HELIOS: Open-Label, Long-Term Extension Study to Investigate the Safety, Tolerability, and Efficacy of DISC-1459 (Bitopertin) in Participants With EPP or XLP

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2023-08-31
Completion:: 2028-06-30

Conditions

Erythropoietic Protoporphyria

Interventions

DRUG

No Results Yet

NCT05879926 | RECRUITING | PHASE3

3960 participants

Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2023-10-18
Completion:: 2032-01-31

Conditions

Breast Cancer

Interventions

DRUG

No Results Yet

NCT05879822 | ACTIVE_NOT_RECRUITING | PHASE2

73 participants

A Study to Evaluate INCB099280 in Participants With Select Solid Tumors Who Are Immune Checkpoint Inhibitor Naive

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2023-10-30
Completion:: 2026-09-30

Conditions

Advanced Solid Tumor

Interventions

DRUG

No Results Yet

NCT05874271 | COMPLETED | NA

794 participants

Short Course Primaquine for the Radical Cure of P. Vivax - Papua New Guinea

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2023-08-07
Completion:: 2025-10-25

Conditions

Vivax Malaria
G6PD Deficiency

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT05868226 | RECRUITING | PHASE1/PHASE2

280 participants

PRE-ISPY Phase I/II Oncology Platform Program

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2023-02-15
Completion:: 2030-12-30

Conditions

HER2-positive Breast Cancer
Metastatic Cancer
Metastatic Breast Cancer
Metastatic
HER2-positive Metastatic Breast Cancer
HER2 Mutation-Related Tumors
HER-2 Protein Overexpression
HER2-negative Breast Cancer
Triple Negative Breast Cancer
HR Positive
Hormone Receptor-positive Breast Cancer
Estrogen Receptor Positive Tumor
Progesterone Receptor-positive Breast Cancer
Hormone Receptor Negative Breast Carcinoma
Solid Tumor
Solid Tumor, Adult
Solid Carcinoma
HER2 Low Breast Cancer
HER2 Low Breast Carcinoma
ER Positive Breast Cancer
PR-positive Breast Cancer
Minimal Residual Disease
Colo-rectal Cancer
Colon Cancer
Rectal Cancer
ctDNA Monitoring
Colorectal Neoplasms
Colonic Neoplasms
Rectal Neoplasms
Neoplasm, Residual
Adenocarcinoma of Colon
Adenocarcinoma

Interventions

DRUG

No Results Yet

NCT05866562 | RECRUITING | PHASE2

76 participants

Dupilumab in the Treatment of Pediatric Alopecia Areata

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2024-07-11
Completion:: 2029-03-31

Conditions

Alopecia Areata

Interventions

DRUG

No Results Yet

NCT05864144 | COMPLETED | PHASE1/PHASE2

98 participants

A Study of SNS-101 (Anti VISTA) Monotherapy and in Combination With Cemiplimab in Patients With Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2023-05-31
Completion:: 2026-06-02

Conditions

Solid Tumor, Adult
Advanced Solid Tumor
Head and Neck Cancer
Breast Cancer
Colon Cancer
Pancreatic Cancer
Gastric Cancer
Esophageal Cancer
Prostate Cancer
Uterine Cancer
Cervix Cancer
Ovarian Cancer
Kidney Cancer
Bladder Cancer
Thyroid Cancer
Melanoma
Sarcoma
Advanced Cancer
Metastatic Cancer
Refractory Cancer
Non Small Cell Lung Cancer
Merkel Cell Carcinoma

Interventions

DRUG

No Results Yet

NCT05862285 | RECRUITING | PHASE3

100 participants

A Rollover Study for Participants Previously Enrolled in a Genentech and/or F. Hoffman-La Roche Sponsored Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2023-06-01
Completion:: 2033-03-01

Conditions

Cancer

Interventions

DRUG

No Results Yet

NCT05860920 | TERMINATED

254 participants

Clinical Diagnostic Performance Evaluation of a Measles Rapid Test in Senegal

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-02
Start Date:: 2025-08-22
Completion:: 2026-06-16

Conditions

Measles

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05852509 | ACTIVE_NOT_RECRUITING | NA

32 participants

Digital Health Physical Activity Program for Older Family Care Partners of Patents With Heart Failure

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2024-07-01
Completion:: 2027-03-31

Conditions

Heart Failure
Caregiver Burden

Interventions

BEHAVIORAL

No Results Yet

NCT05851924 | RECRUITING | PHASE2

60 participants

A Study of NALIRIFOX in Combination With Radiation Therapy in People With Pancreatic Ductal Adenocarcinoma (PDAC)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2023-05-12
Completion:: 2026-09-01

Conditions

Pancreatic Ductal Adenocarcinoma

Interventions

DRUG
COMBINATION_PRODUCT

No Results Yet

NCT05837767 | RECRUITING | NA

26 participants

A Study of Radiation Therapy to Treat Solid Tumor Cancer That Has Spread to Soft Tissue

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2023-07-24
Completion:: 2027-07-24

Conditions

Invasive Ductal Breast Carcinoma
Invasive Ductal Breast Carcinoma Stage IV
Lobular Breast Carcinoma
Lobular Breast Carcinoma Stage IV
Non Small Cell Lung Cancer
NSCLC
Gastrointestinal Cancer
Gastrointestinal Squamous Cell Cancer
Gastrointestinal Adenocarcinoma
Pancreatic Cancer
Bladder Cancer
Renal Cell Carcinoma
Melanoma
Sarcoma
Metastatic Solid Tumor

Interventions

RADIATION

No Results Yet

NCT05826054 | COMPLETED | PHASE1

15 participants

Montbretin Clinical Trial in Healthy Volunteers and Type 2 Diabetics

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2023-12-01
Completion:: 2025-11-25

Conditions

Type 2 Diabetes

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT05813964 | RECRUITING | PHASE3

524 participants

Efficacy, Acceptability and Safety of Event-driven HIV PrEP Using TAF/FTC in MSM in Thailand and France.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2024-06-05
Completion:: 2027-12-31

Conditions

HIV/AIDS

Interventions

DRUG

No Results Yet

NCT05796453 | COMPLETED | NA

470 participants

Post Market Clinical Follow-up (PMCF) Study of Clareon Vivity & Clareon PanOptix

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2023-09-19
Completion:: 2026-08-21

Conditions

Aphakia
Astigmatism
Presbyopia

Interventions

DEVICE

No Results Yet

NCT05785910 | COMPLETED | NA

14 participants

Adaptation of the Uniform Data Set for Telematic Administration

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2021-09-14
Completion:: 2022-01-31

Conditions

Dementia, Mild
Dementia of Alzheimer Type

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05772273 | RECRUITING | NA

43 participants

PD-1 Inhibitor, Azacitidine and Low-dose DLI in AML Relapse After Allo-HSCT

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2023-03-15
Completion:: 2027-07-01

Conditions

Acute Myeloid Leukemia

Interventions

DRUG
BIOLOGICAL

No Results Yet

NCT05770570 | RECRUITING | PHASE2

1889 participants

Taxi ROADmAP (Realizing Optimization Around Diet And Physical Activity)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2022-12-22
Completion:: 2027-02-26

Conditions

Overweight
Overweight and Obesity
Overweight or Obesity
Obesity
Obese

Interventions

BEHAVIORAL

No Results Yet

NCT05763407 | ACTIVE_NOT_RECRUITING | NA

25 participants

Early Feasibility Study of the NORM™ System in Heart Failure Patients (FUTURE-HFII)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2023-06-19
Completion:: 2027-06-30

Conditions

Heart Failure

Interventions

DEVICE

No Results Yet

NCT05761080 | RECRUITING | PHASE4

772 participants

Fast Track Therapeutic Model in Acute Complicated Appendicitis in Pediatrics

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2021-04-22
Completion:: 2027-11-30

Conditions

Laparoscopic Appendectomy
Complicated Appendicitis
Periappendicular Abscess

Interventions

DRUG

No Results Yet

NCT05754034 | RECRUITING | NA

1600 participants

Building Respiratory Support in East Africa Through High Flow Versus Standard Flow Oxygen Evaluation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2023-10-11
Completion:: 2026-09-30

Conditions

Acute Hypoxemia

Interventions

DEVICE
OTHER

No Results Yet

NCT05753748 | RECRUITING | NA

680 participants

Surveillance vs. Endoscopic Therapy for Barrett's Esophagus With Low-grade Dysplasia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2023-01-24
Completion:: 2029-04-30

Conditions

Barretts Esophagus With Dysplasia
Barrett Esophagus
Esophageal Adenocarcinoma

Interventions

PROCEDURE

No Results Yet

NCT05743244 | ACTIVE_NOT_RECRUITING | PHASE2

78 participants

Janus Kinase (JAK) Inhibitors to Preserve C-Peptide Production in New Onset Type 1 Diabetes (T1D)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2023-10-19
Completion:: 2026-10-30

Conditions

Diabetes Mellitus, Type 1

Interventions

DRUG

No Results Yet

NCT05739279 | COMPLETED

102 participants

Sarcopenia and Related Factors in Lipedema

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-02
Start Date:: 2023-01-01
Completion:: 2025-12-31

Conditions

Lipedema
Sarcopenia
Musculoskeletal Diseases

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05730582 | ENROLLING_BY_INVITATION | NA

500000 participants

Increasing Uptake of EHR-enabled Population Health Outreach Strategies to Improve Diabetes Screening

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2024-03-05
Completion:: 2026-09-01

Conditions

Diabetes Mellitus, Type 2
Pre Diabetes

Interventions

BEHAVIORAL

No Results Yet

NCT05721846 | COMPLETED | PHASE1

20 participants

Nivolumab With Ipilimumab Combined With TGFβ-15 Peptide Vaccine and Radiotherapy for Pancreatic Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2023-05-03
Completion:: 2026-03-16

Conditions

Pancreatic Cancer

Interventions

DRUG
RADIATION
BIOLOGICAL

No Results Yet

NCT05718583 | COMPLETED | NA

20 participants

Effects of Administration of SCFA in Rheumatoid Arthritis Inadequate Responders

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2023-02-01
Completion:: 2025-02-20

Conditions

Rheumatoid Arthritis

Interventions

DIETARY_SUPPLEMENT

Results Available

NCT05712772 | ACTIVE_NOT_RECRUITING | NA

80 participants

Neuro-affective Response to Light in Depressed Adolescents and Young Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2023-06-14
Completion:: 2026-09-14

Conditions

Depression in Adolescence
Depression in Adults

Interventions

OTHER

No Results Yet

NCT05709197 | COMPLETED | NA

256 participants

The Effectiveness of Adding Braun Anastomosis to Standard Child Reconstruction After Pancreatoduodenectomy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2023-04-17
Completion:: 2026-07-24

Conditions

Pancreatic Disease
Pancreatic Cancer
Delayed Gastric Emptying

Interventions

PROCEDURE

No Results Yet

NCT05707273 | ACTIVE_NOT_RECRUITING | PHASE1

18 participants

CD19-Car T Cell Therapy for the Treatment of Older Adults With Acute Lymphoblastic Leukemia in First Remission

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2023-04-26
Completion:: 2026-09-22

Conditions

B Acute Lymphoblastic Leukemia

Interventions

DRUG
PROCEDURE
OTHER

No Results Yet

NCT05704244 | ACTIVE_NOT_RECRUITING | PHASE3

25 participants

Safety and Efficacy of FE 999326 Administered Intravesically to Japanese Subjects With High-grade, BCG Unresponsive, Non-muscle Invasive Bladder Cancer (NMIBC)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2022-12-21
Completion:: 2029-11-30

Conditions

Bladder Cancer

Interventions

DRUG

No Results Yet

NCT05700903 | TERMINATED | PHASE4

10 participants

Contributions to Hypertension With Androgen Deprivation Therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2023-09-20
Completion:: 2025-07-16

Conditions

Androgen Deprivation Therapy
Prostate Cancer
Hypertension
Autonomic Dysfunction
Renal Disease

Interventions

DRUG

Results Available

NCT05698602 | TERMINATED | NA

10 participants

Safety and Performance of NivolisMonitor and NivolisAnton for Monitoring Patients on Ventilatory Assistance at Home

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2023-04-24
Completion:: 2026-08-28

Conditions

Respiratory Insufficiency
Respiratory Failure
Home Monitoring

Interventions

DEVICE

No Results Yet