A Study of Radiation Therapy to Treat Solid Tumor Cancer That Has Spread to Soft Tissue
NCT05837767 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 26
Last updated 2026-03-30
Summary
The purpose of this study is to find out whether lattice radiation therapy (LRT) is an effective radiation therapy technique when compared to standard stereotactic body radiation therapy (SBRT). The study will also study how the different radiation therapy techniques (LRT and SBRT) affect how many immune cells are able to attack and kill tumor cells (immune infiltration).
Conditions
- Invasive Ductal Breast Carcinoma
- Invasive Ductal Breast Carcinoma Stage IV
- Lobular Breast Carcinoma
- Lobular Breast Carcinoma Stage IV
- Non Small Cell Lung Cancer
- NSCLC
- Gastrointestinal Cancer
- Gastrointestinal Squamous Cell Cancer
- Gastrointestinal Adenocarcinoma
- Pancreatic Cancer
- Bladder Cancer
- Renal Cell Carcinoma
- Melanoma
- Sarcoma
- Metastatic Solid Tumor
Interventions
- RADIATION
-
Palliative radiotherapy
Palliative radiotherapy (RT) will be performed using external beam ionizing radiation in accordance with standard practice
Sponsors & Collaborators
-
Varian Medical Systems
collaborator INDUSTRY -
Memorial Sloan Kettering Cancer Center
lead OTHER
Principal Investigators
-
Atif Khan, MD · Memorial Sloan Kettering Cancer Center
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-07-24
- Primary Completion
- 2026-07-24
- Completion
- 2026-07-24
- FDA Device
- Yes
Countries
- United States
Study Locations
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