Clinical Trials Updated in 2026

NCT05049993 | ACTIVE_NOT_RECRUITING

76 participants

Pyrocarbon Clinical Follow-up Study

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-01
Start Date:: 2021-10-27
Completion:: 2027-05-31

Conditions

Osteoarthritis of the Shoulder
Avascular Necrosis
Traumatic Arthritis

Interventions

DEVICE

No Results Yet

NCT05047172 | ACTIVE_NOT_RECRUITING | PHASE3

1683 participants

Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-01
Start Date:: 2022-08-02
Completion:: 2027-01-31

Conditions

Intracranial Arteriosclerosis
Stroke

Interventions

DRUG
OTHER

No Results Yet

NCT05032092 | COMPLETED | NA

235 participants

Evaluation of Efficacy of Comprehensive Genomic Tumour Profiling (CGP) From Liquid and/or Tissue Biopsy in Patients With Locally Advanced and/or Metastatic Solid Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-01
Start Date:: 2021-11-24
Completion:: 2026-04-14

Conditions

Locally Advanced Carcinoma
Metastatic Cancer

Interventions

DIAGNOSTIC_TEST
GENETIC

No Results Yet

NCT05026723 | ACTIVE_NOT_RECRUITING | NA

200 participants

Food as Medicine for HIV and Diabetes

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-01
Start Date:: 2021-10-04
Completion:: 2026-10-31

Conditions

Diabetes Mellitus, Type 2
HIV Infections
PreDiabetes

Interventions

BEHAVIORAL

No Results Yet

NCT04996797 | COMPLETED | PHASE2

178 participants

A Phase 2 Safety and Efficacy Study of Tulisokibart (MK-7240/PRA023) in Subjects With Moderately to Severely Active Ulcerative Colitis (MK-7240-005)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-01
Start Date:: 2021-07-14
Completion:: 2023-06-06

Conditions

Ulcerative Colitis

Interventions

DRUG
DEVICE
OTHER

Results Available

NCT04977986 | COMPLETED | PHASE3

257 participants

Clinical Study of Cannabidiol in Children, Adolescents, and Young Adults With Fragile X Syndrome

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-01
Start Date:: 2021-09-13
Completion:: 2025-08-29

Conditions

Fragile X Syndrome
Fragile X Syndrome (FXS)

Interventions

DRUG

No Results Yet

NCT04946851 | ENROLLING_BY_INVITATION

1400 participants

Addictions Neuroclinical Assessment (ANA)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-01
Start Date:: 2021-08-12
Completion:: 2031-12-31

Conditions

Normal Physiology
Alcohol Use Disorder

No Results Yet

NCT04933539 | ACTIVE_NOT_RECRUITING | PHASE2

14 participants

Subcutaneous Daratumumab, Once Weekly Carfilzomib, and Dexamethasone (DKd) in Patients With High-Risk Smoldering Multiple Myeloma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-01
Start Date:: 2022-10-31
Completion:: 2026-08-31

Conditions

Multiple Myeloma

Interventions

DRUG
BIOLOGICAL

No Results Yet

NCT04928677 | RECRUITING | PHASE1

50 participants

A Study of Codrituzumab in Children and Young Adults With Solid Tumors and Have Not Responded to Treatment or Have Come Back After Treatment

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-01
Start Date:: 2021-06-09
Completion:: 2027-06-30

Conditions

Primary Extra-cranial Solid Tumor
Recurrent or Refractory Glypican 3 (GPC3)

Interventions

DRUG

No Results Yet

NCT04926922 | COMPLETED

200 participants

PREVAIL VIIIa: Evaluation of Latent Tuberculosis Infection Screening Methods in People Living With Retroviral Infection in Liberia

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-01
Start Date:: 2021-07-27
Completion:: 2026-04-30

Conditions

Tuberculosis
HIV

No Results Yet

NCT04866680 | ACTIVE_NOT_RECRUITING | NA

136 participants

Personalized Circulating DNA Follow-up in Melanoma (PERCIMEL)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-01
Start Date:: 2023-01-31
Completion:: 2027-11-30

Conditions

Melanoma

Interventions

PROCEDURE

No Results Yet

NCT04864886 | RECRUITING

300 participants

Metabolic Profiling of Immune Responses in Immune-mediated Diseases

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-01
Start Date:: 2021-08-10
Completion:: 2027-06-30

Conditions

Primary Immunodeficiency
Psoriasis
Atopic Dermatitis
Immune-mediated Diseases

No Results Yet

NCT04829136 | RECRUITING | NA

100 participants

Sustained Oral Fiber Supplementation for Patients Undergoing Treatment for Hematological Malignancies

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-01
Start Date:: 2022-06-22
Completion:: 2027-07-31

Conditions

Hematopoietic and Lymphatic System Neoplasm

Interventions

DIETARY_SUPPLEMENT
OTHER
PROCEDURE

No Results Yet

NCT04789330 | COMPLETED | PHASE4

3626 participants

Norepinephrine vs Phenylephrine During General Anesthesia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-01
Start Date:: 2021-07-01
Completion:: 2022-04-01

Conditions

Anesthesia
Surgery
Hypotension

Interventions

DRUG

Results Available

NCT04786262 | RECRUITING | PHASE3

57 participants

A Safety, Tolerability, and Efficacy Study of VX-880 and VX-017 in Participants With Type 1 Diabetes

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-01
Start Date:: 2021-03-29
Completion:: 2027-12-31

Conditions

Diabetes Mellitus, Type 1
Impaired Hypoglycemic Awareness
Severe Hypoglycemia

Interventions

BIOLOGICAL

No Results Yet

NCT04776694 | AVAILABLE

Compassionate Use or Expanded Access of Dupilumab

Study Type:: EXPANDED_ACCESS
Last Updated:: 2026-09-01

Conditions

Type 2 Inflammatory Disorders

Interventions

DRUG

No Results Yet

NCT04750928 | RECRUITING | PHASE1/PHASE2

55 participants

Cyclin-Dependent Kinase (CDK)4/6 Inhibitor Abemaciclib for Neurofibromatosis Type I (NF1) Related Atypical Neurofibromas

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-01
Start Date:: 2021-11-29
Completion:: 2028-12-31

Conditions

Neurofibromatosis 1

Interventions

DRUG

No Results Yet

NCT04737720 | COMPLETED

1 participants

Intravenous ACP-501 for Familial LCAT Deficiency (rhLCAT)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-01
Start Date:: 2013-01-24
Completion:: 2013-12-12

Conditions

Familial LCAT Deficiency

Interventions

DRUG

No Results Yet

NCT04729283 | COMPLETED

94 participants

Comparison of Quality of Life and Functionnal Resultats After Sigmodectomy Between Diverticulitis and Cancer

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-01
Start Date:: 2021-04-12
Completion:: 2025-04-28

Conditions

Sigmoid Cancer
Sigmoid Diverticulosis

Interventions

PROCEDURE

No Results Yet

NCT04657081 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

101 participants

Pharmacokinetics, Safety, and Efficacy of ASTX727 in Combination With Venetoclax in Acute Myeloid Leukemia (AML)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-01
Start Date:: 2021-02-09
Completion:: 2024-09-30

Conditions

Acute Myeloid Leukemia

Interventions

DRUG

No Results Yet

NCT04651296 | COMPLETED | PHASE2

142 participants

Compassion Meditation vs. Health Education for Veterans

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-01
Start Date:: 2022-01-04
Completion:: 2025-08-21

Conditions

Chronic Pain
Stress Disorders, Posttraumatic
Depression

Interventions

BEHAVIORAL

Results Available

NCT04645160 | RECRUITING | PHASE1/PHASE2

31 participants

Evaluating Efficacy of Tivozanib (AV-951) in Biliary Tract Cancers

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-01
Start Date:: 2022-03-04
Completion:: 2028-12-31

Conditions

Cholangiocarcinoma
Bile Duct Neoplasm
Biliary Tract Malignancy

Interventions

DRUG

No Results Yet

NCT04637503 | NOT_YET_RECRUITING | PHASE1/PHASE2

100 participants

4SCAR-T Therapy Targeting GD2, PSMA and CD276 for Treating Neuroblastoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-01
Start Date:: 2026-12-31
Completion:: 2029-12-31

Conditions

Neuroblastoma

Interventions

BIOLOGICAL

No Results Yet

NCT04633811 | ACTIVE_NOT_RECRUITING | NA

14 participants

Effect of Weight Loss on Urinary Oxalate Excretion in Obese Calcium Oxalate Kidney Stone Formers

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-01
Start Date:: 2021-12-03
Completion:: 2025-12-31

Conditions

Kidney Stone

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT04631042 | RECRUITING

1100 participants

Developing Brain, Impulsivity and Compulsivity

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-01
Start Date:: 2022-09-30
Completion:: 2030-12-31

Conditions

Typical Development
Obsessive Compulsive Disorder
Conduct Disorder
Attention Deficit Hyperactivity Disorder
Autism Spectrum Disorder

No Results Yet

NCT04619004 | ACTIVE_NOT_RECRUITING | PHASE2

277 participants

HERTHENA-Lung01: Patritumab Deruxtecan in Subjects With Metastatic or Locally Advanced EGFR-mutated Non-Small Cell Lung Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-01
Start Date:: 2021-02-02
Completion:: 2022-11-21

Conditions

Non-Small Cell Lung Cancer Metastatic
Non-Small Cell Lung Cancer With Mutation in Epidermal Growth Factor Receptor

Interventions

DRUG

Results Available

NCT04595760 | ACTIVE_NOT_RECRUITING

231 participants

Factors Influencing Fertility or Pregnancy Health

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-01
Start Date:: 2020-10-19
Completion:: 2030-12-31

Conditions

Menstrual Cycles
Conception
Early Pregnancy Loss
Pregnancy Outcomes

No Results Yet

NCT04570956 | TERMINATED | PHASE2

65 participants

Oral Tamoxifen vs. TamGel vs. Control in Women With Atypical Hyperplasia, Lobular Carcinoma In Situ, or Increased Breast Cancer Risk

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-01
Start Date:: 2021-07-26
Completion:: 2024-10-15

Conditions

Breast Atypical Hyperplasia
Breast Lobular Carcinoma in Situ
Breast Atypical Lobular Hyperplasia
Breast Carcinoma

Interventions

DRUG
OTHER

Results Available

NCT04570423 | RECRUITING | PHASE2

40 participants

A Study to Evaluate the Safety and Pharmacokinetics of Eflapegrastim in Pediatric Participants With Solid Tumors or Lymphomas and Treated With Myelosuppressive Chemotherapy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-01
Start Date:: 2021-05-20
Completion:: 2027-10-31

Conditions

Solid Tumors
Lymphoma

Interventions

DRUG

No Results Yet

NCT04557956 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

16 participants

Testing the Addition of the Anti-cancer Drug, Tazemetostat, to (Dabrafenib and Trametinib) for Metastatic Melanoma That Has Progressed on the Usual Treatment

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-01
Start Date:: 2021-08-19
Completion:: 2025-10-15

Conditions

Clinical Stage IV Cutaneous Melanoma AJCC v8
Metastatic Melanoma

Interventions

PROCEDURE
DRUG

Results Available

NCT04553211 | COMPLETED | NA

663 participants

Expedited Partner Therapy and the HIV Prevention Cascade

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-01
Start Date:: 2022-04-25
Completion:: 2024-04-30

Conditions

HIV-1-infection
Gonorrhea Male
Chlamydia
Partner Communication

Interventions

BEHAVIORAL

Results Available

NCT04546399 | RECRUITING | PHASE2

461 participants

A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-01
Start Date:: 2020-12-17
Completion:: 2028-06-30

Conditions

Down Syndrome
Recurrent B Acute Lymphoblastic Leukemia

Interventions

RADIATION
DRUG
PROCEDURE
BIOLOGICAL

No Results Yet

NCT04526665 | ACTIVE_NOT_RECRUITING | PHASE3

161 participants

Study of Elafibranor in Patients With Primary Biliary Cholangitis (PBC)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-01
Start Date:: 2020-09-24
Completion:: 2023-06-01

Conditions

Primary Biliary Cirrhosis

Interventions

DRUG

Results Available

NCT04521803 | COMPLETED | PHASE2

52 participants

High vs. Standard Dose Rifampicin for Effusive Tuberculous Pericarditis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-01
Start Date:: 2022-01-10
Completion:: 2026-03-26

Conditions

Tuberculous Pericarditis
HIV Status

Interventions

DRUG

No Results Yet

NCT04501861 | COMPLETED | PHASE3

164 participants

Hemodynamic Effect of Norepinephrine Versus Vasopressin on the Pulmonary Circulation in Cardiac Surgery Patients:

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-01
Start Date:: 2020-11-05
Completion:: 2023-08-22

Conditions

Cardiac Disease

Interventions

DRUG

Results Available

NCT04484272 | COMPLETED | NA

239 participants

A Stress and Pain Self-management m-Health App for Adult Outpatients With Sickle Cell Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-01
Start Date:: 2021-04-29
Completion:: 2026-03-02

Conditions

Sickle Cell Disease

Interventions

BEHAVIORAL

No Results Yet

NCT04464980 | ACTIVE_NOT_RECRUITING | PHASE2

1516 participants

Optimizing Retention, Duration and Discontinuation Strategies for Opioid Use Disorder Pharmacotherapy (RDD)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-01
Start Date:: 2021-06-08
Completion:: 2026-12-31

Conditions

Opioid Use Disorder (OUD)

Interventions

DRUG
BEHAVIORAL

No Results Yet

NCT04446910 | COMPLETED | NA

50 participants

Using Technology to Reduce Youth Substance Use

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-01
Start Date:: 2020-05-01
Completion:: 2025-04-01

Conditions

Drug Use

Interventions

BEHAVIORAL

Results Available

NCT04442451 | RECRUITING | NA

80 participants

Mechanisms of Fatigability With Diabetes

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-01
Start Date:: 2022-09-01
Completion:: 2027-07-01

Conditions

Pre-diabetes
Type 2 Diabetes

Interventions

OTHER

No Results Yet

NCT04431024 | RECRUITING

300 participants

Prospective Evaluation of High Resolution Dual Energy Computed Tomographic Imaging, Noninvasive (Liquid) Biopsies, and Minimally Invasive Surgical Surveillance for Early Detection of Mesotheliomas in Patients With BAP1 Tumor Predisposition Syndrome

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-01
Start Date:: 2021-03-30
Completion:: 2038-06-30

Conditions

Familial Cancer
BRCA1-Associated Protein-1 (BAP1) Mutations
Tumor Predisposition Syndrome (TPDS)
Mesothelioma

No Results Yet