Clinical Trials

NCT05237986 | RECRUITING

60 participants

Cognitive Aftereffects of Neurotoxicity in Children and Young Adults With Relapsed/Refractory Hematologic Malignancies Who Receive CAR T-cell Therapy

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-31

Start Date:

2025-06-23

Completion:

2028-09-01

Conditions

• Lymphoma
• Leukemia

No Results Yet

NCT05226494 | ACTIVE_NOT_RECRUITING | PHASE1

34 participants

Safety and Tolerability of Fb-PMT in Recurrent Glioblastoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2022-06-23

Completion:

2027-06-30

Conditions

• Glioma, Malignant

Interventions

• DRUG

No Results Yet

NCT05207670 | ACTIVE_NOT_RECRUITING | PHASE2

320 participants

A Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Mosunetuzumab Monotherapy in Participants With Select B-Cell Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2022-02-01

Completion:

2027-07-31

Conditions

• Non-Hodgkin Lymphoma

Interventions

• DRUG

No Results Yet

NCT05198323 | ACTIVE_NOT_RECRUITING | PHASE2

66 participants

A Study to Evaluate the Safety and Efficacy of LT3001 Drug Product in Subjects AIS Undergoing EVT

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2022-08-11

Completion:

2026-12-31

Conditions

• Acute Ischemic Stroke

Interventions

• DRUG

No Results Yet

NCT05198154 | ACTIVE_NOT_RECRUITING

100 participants

ctDNA Analysis to Monitor the Risk of Progression After First-line Immunotherapy in Patients With Advanced NSCLC

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-31

Start Date:

2022-01-24

Completion:

2027-11-30

Conditions

• Advanced Lung Non-Small Cell Carcinoma

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT05197049 | ACTIVE_NOT_RECRUITING | PHASE3

350 participants

A Study of Guselkumab Subcutaneous Therapy in Participants With Moderately to Severely Active Crohn's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2022-01-19

Completion:

2023-07-04

Conditions

• Crohn Disease

Interventions

• DRUG

Results Available

NCT05189925 | RECRUITING | PHASE1

25 participants

NADPH Oxidase Correction in mRNA-transfected Granulocyte-enriched Cells in Chronic Granulomatous Disease (CGD)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2022-07-22

Completion:

2027-07-01

Conditions

• Chronic Granulomatous Disease
• Infection

Interventions

• BIOLOGICAL

No Results Yet

NCT05163808 | COMPLETED | PHASE2/PHASE3

163 participants

A Randomized Study of BPN14770 in Male Adolescents (Aged 9 to < 18 Years) With Fragile X Syndrome

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2022-03-29

Completion:

2025-09-02

Conditions

• Fragile X Syndrome

Interventions

• DRUG

No Results Yet

NCT05155033 | RECRUITING | PHASE2

78 participants

Phase II Trial of Combination Anti-PD-1 and Aldesleukin for Metastatic Melanoma and Renal Cell Carcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2022-08-18

Completion:

2031-09-01

Conditions

• Metastatic Melanoma
• Advanced Locoregional Melanoma
• Metastatic Renal Cell Carcinoma
• Clear Cell Histology

Interventions

• DRUG

No Results Yet

NCT05150652 | COMPLETED | PHASE2

8 participants

Neoadjuvant Endocrine Therapy in ER-positive, HER2-negative Early Stage Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2022-02-18

Completion:

2025-12-09

Conditions

• Breast Cancer
• HER2-negative Breast Cancer
• Node-negative Breast Cancer
• Breast Carcinoma

Interventions

• DRUG

No Results Yet

NCT05144893 | WITHDRAWN | NA

0 participants

Brief Virtual Mindfulness-based Group Intervention With Social Support for Perinatal Individuals

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2024-05-01

Completion:

2025-07-31

Conditions

• Substance Use
• Pregnancy Related
• Mental Health

Interventions

• BEHAVIORAL

No Results Yet

NCT05129631 | COMPLETED | NA

30 participants

HEARTPrep: A Virtually-delivered Psychosocial Intervention for Mothers Expecting a Baby With Congenital Heart Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2023-07-14

Completion:

2025-05-31

Conditions

• Congenital Heart Disease

Interventions

• BEHAVIORAL

Results Available

NCT05126719 | ACTIVE_NOT_RECRUITING | PHASE2

238 participants

A Study to Evaluate the Efficacy and Safety of MRG003 in Patients With Recurrent Metastatic Nasopharyngeal Carcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2023-04-06

Completion:

2024-12-30

Conditions

• Recurrent or Metastatic Nasopharyngeal Carcinoma

Interventions

• DRUG

No Results Yet

NCT05120635 | RECRUITING | NA

80 participants

Intracranial Neurophysiological Signatures of Fear and Anxiety in Humans

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2021-10-01

Completion:

2027-05-31

Conditions

• Fear
• GAD
• Emotional Memory
• PTSD

Interventions

• DEVICE
• BEHAVIORAL

No Results Yet

NCT05112601 | RECRUITING | PHASE2

81 participants

Testing Nivolumab With or Without Ipilimumab in Deficient Mismatch Repair System (dMMR) Recurrent Endometrial Carcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2022-06-02

Completion:

2032-07-30

Conditions

• Endometrial Adenocarcinoma
• Endometrial Clear Cell Adenocarcinoma
• Endometrial Dedifferentiated Carcinoma
• Endometrial Endometrioid Adenocarcinoma
• Endometrial Mixed Cell Adenocarcinoma
• Endometrial Mucinous Adenocarcinoma
• Endometrial Undifferentiated Carcinoma
• Endometrioid Adenocarcinoma
• Recurrent Endometrial Carcinoma

Interventions

• PROCEDURE
• BIOLOGICAL

No Results Yet

NCT05092100 | ENROLLING_BY_INVITATION | NA

2900 participants

Neural Mechanisms for Reducing Interference During Episodic Memory Formation

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2021-09-29

Completion:

2026-12-31

Conditions

• Behavior

Interventions

• BEHAVIORAL
• OTHER

No Results Yet

NCT05081908 | COMPLETED | NA

25 participants

Multisession Radiosurgery in Residual/Recurrent Grade II Meningiomas.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2017-05-17

Completion:

2019-05-07

Conditions

• Meningioma Atypical

Interventions

• PROCEDURE

No Results Yet

NCT05051436 | RECRUITING | PHASE4

96 participants

The Effects of Mirabegron and Tadalafil on Glucose Tolerance in Prediabetics

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2021-12-13

Completion:

2027-01-31

Conditions

• Pre-diabetes
• Obesity

Interventions

• DRUG

No Results Yet

NCT05047172 | ACTIVE_NOT_RECRUITING | PHASE3

1683 participants

Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2022-08-02

Completion:

2027-01-31

Conditions

• Intracranial Arteriosclerosis
• Stroke

Interventions

• DRUG
• OTHER

No Results Yet

NCT05035030 | ACTIVE_NOT_RECRUITING | PHASE3

62 participants

Long-term Safety and Efficacy of Odevixibat in Patients With Alagille Syndrome

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2021-09-03

Completion:

2026-12-31

Conditions

• Alagille Syndrome

Interventions

• DRUG

No Results Yet

NCT05013450 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

33 participants

Dupilumab_Metastatic NSCLC

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2021-09-10

Completion:

2025-09-18

Conditions

• Metastatic Non-small Cell Lung Cancer

Interventions

• DRUG

No Results Yet

NCT04955795 | ACTIVE_NOT_RECRUITING | NA

308 participants

Telemedicine for Unhealthy Alcohol Use in Persons Living With HIV Using CETA

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2023-05-04

Completion:

2026-08-31

Conditions

• Hiv
• Alcohol Problem

Interventions

• BEHAVIORAL

No Results Yet

NCT04933539 | ACTIVE_NOT_RECRUITING | PHASE2

14 participants

Subcutaneous Daratumumab, Once Weekly Carfilzomib, and Dexamethasone (DKd) in Patients With High-Risk Smoldering Multiple Myeloma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2022-10-31

Completion:

2026-08-31

Conditions

• Multiple Myeloma

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT04927416 | RECRUITING | PHASE2

54 participants

The Role of 68-Gallium-DOTATATE-PET/CT in the Imaging of Metastatic Thyroid Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2021-10-25

Completion:

2030-11-30

Conditions

• Metastic Thyroid Cancer

Interventions

• DRUG

No Results Yet

NCT04926922 | COMPLETED

200 participants

PREVAIL VIIIa: Evaluation of Latent Tuberculosis Infection Screening Methods in People Living With Retroviral Infection in Liberia

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-31

Start Date:

2021-07-27

Completion:

2026-04-30

Conditions

• Tuberculosis
• HIV

No Results Yet

NCT04925063 | ACTIVE_NOT_RECRUITING | PHASE2

266 participants

The Effect of Metformin in Patients With Newly Diagnosed mHSPC

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2021-06-16

Completion:

2026-08-30

Conditions

• Metastatic Prostate Cancer

Interventions

• DRUG

No Results Yet

NCT04888923 | RECRUITING

2000 participants

Natural History of the Human Biological Response to Environmental Exposure and Injury

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-31

Start Date:

2021-11-16

Completion:

2031-12-31

Conditions

• Inflammation
• Normal Controls
• Metabolic Disease

No Results Yet

NCT04881240 | RECRUITING | PHASE1

60 participants

Study of CD19 Allogeneic Memory T-cell Therapy for Relapsed/Refractory CD19+ Leukemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2024-02-14

Completion:

2027-07-01

Conditions

• Acute Lymphoblastic Leukemia, in Relapse
• Acute Lymphoblastic Leukemia, Refractory
• Pediatric ALL

Interventions

• BIOLOGICAL
• DRUG
• DEVICE
• PROCEDURE

No Results Yet

NCT04877288 | RECRUITING | PHASE3

102 participants

A Study to Evaluate the Benefits and Risks of Conversion of Existing Adolescent Kidney Transplant Recipients Aged 12 to <18 Years to a Belatacept-based Immunosuppressive Regimen as Compared to Continuation of a Calcineurin Inhibitor-based Regimen, and Their Adherence to Immunosuppressive Medications

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2021-07-21

Completion:

2032-12-30

Conditions

• Renal Allograft Recipients

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT04868344 | COMPLETED | PHASE1

61 participants

A Study of MRG003 in Patients With Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2018-05-09

Completion:

2021-03-29

Conditions

• Advanced Solid Tumors

Interventions

• DRUG

No Results Yet

NCT04839614 | RECRUITING | NA

30 participants

Concurrent Laparoscopic Hysterectomy and Weight Loss Surgery in Obese Patients With Endometrial Carcinoma or Endometrial Intraepithelial Neoplasia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2021-08-01

Completion:

2028-06-30

Conditions

• Endometrial Carcinoma
• Obesity
• EIN
• Endometrial Intraepithelial Neoplasia
• Endometrial Cancer Stage I

Interventions

• OTHER

No Results Yet

NCT04827368 | COMPLETED

292 participants

Volatile Organic Compounds (VOCs) in Active Inflammatory Bowel Disease

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-31

Start Date:

2021-03-22

Completion:

2026-06-30

Conditions

• IBD
• Crohn Disease
• Ulcerative Colitis

Interventions

• OTHER

No Results Yet

NCT04765696 | ACTIVE_NOT_RECRUITING

1964 participants

Prospective RELOC-AGE: How Do Housing Choices and Relocation Matter for Active Ageing?

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-31

Start Date:

2021-03-01

Completion:

2028-12-31

Conditions

• Active Ageing

Interventions

• OTHER

No Results Yet

NCT04765683 | COMPLETED

220 participants

Video, Telephone or Face-to-face Surgical Consultations: a Survey of Patients' and Surgeons' Views

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-31

Start Date:

2021-08-20

Completion:

2021-10-25

Conditions

• Surgery

Interventions

• OTHER

No Results Yet

NCT04751786 | ACTIVE_NOT_RECRUITING | PHASE1

15 participants

Dose Escalation Study of Immunomodulatory Nanoparticles

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2021-01-11

Completion:

2026-12-31

Conditions

• Advanced Solid Tumor

Interventions

• DRUG

No Results Yet

NCT04750928 | RECRUITING | PHASE1/PHASE2

55 participants

Cyclin-Dependent Kinase (CDK)4/6 Inhibitor Abemaciclib for Neurofibromatosis Type I (NF1) Related Atypical Neurofibromas

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2021-11-29

Completion:

2028-12-31

Conditions

• Neurofibromatosis 1

Interventions

• DRUG

No Results Yet

NCT04736173 | ACTIVE_NOT_RECRUITING | PHASE2

169 participants

Study Evaluating Effectiveness and Safety of Zimberelimab and Domvanalimab in Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2021-02-08

Completion:

2027-05-31

Conditions

• Non Small Cell Lung Cancer
• Nonsquamous Non Small Cell Lung Cancer
• Squamous Non Small Cell Lung Cancer
• Lung Cancer

Interventions

• DRUG

No Results Yet

NCT04708470 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

55 participants

A Phase I/II Study of Combination Immunotherapy for Advanced Cancers Including HPV-Associated Malignancies, Small Bowel, and Colon Cancers

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2021-10-05

Completion:

2026-11-30

Conditions

• Oropharyngeal Cancer
• Neck Cancer
• Human Papillomavirus
• HPV
• Anal Cancer
• Cervical Cancer
• Penile Cancer
• Vulvar Cancer
• Vaginal Cancer
• Colon Cancer

Interventions

• DRUG

No Results Yet

NCT04700748 | COMPLETED | NA

150 participants

Diffusion-weighted MRI to Predict Treatment Response in Stereotactic Radiotherapy of Central Nervous System (CNS) Metastases

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2020-12-28

Completion:

2024-04-30

Conditions

• Radiotherapy
• Brain Metastases
• Sensitivity
• Radionecrosis

Interventions

• RADIATION

No Results Yet

NCT04685200 | RECRUITING

143 participants

Unraveling the Mechanisms Underlying Primary Sclerosing Cholangitis Through a Multidisciplinary, Integrative Research Approach

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-31

Start Date:

2023-03-31

Completion:

2026-10-31

Conditions

• Primary Sclerosing Cholangitis

No Results Yet