Clinical Trials

NCT05198154 | ACTIVE_NOT_RECRUITING

100 participants

ctDNA Analysis to Monitor the Risk of Progression After First-line Immunotherapy in Patients With Advanced NSCLC

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-31

Start Date:

2022-01-24

Completion:

2027-11-30

Conditions

• Advanced Lung Non-Small Cell Carcinoma

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT05197049 | ACTIVE_NOT_RECRUITING | PHASE3

350 participants

A Study of Guselkumab Subcutaneous Therapy in Participants With Moderately to Severely Active Crohn's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2022-01-19

Completion:

2023-07-04

Conditions

• Crohn Disease

Interventions

• DRUG

Results Available

NCT05163808 | COMPLETED | PHASE2/PHASE3

163 participants

A Randomized Study of BPN14770 in Male Adolescents (Aged 9 to < 18 Years) With Fragile X Syndrome

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2022-03-29

Completion:

2025-09-02

Conditions

• Fragile X Syndrome

Interventions

• DRUG

No Results Yet

NCT05155033 | RECRUITING | PHASE2

78 participants

Phase II Trial of Combination Anti-PD-1 and Aldesleukin for Metastatic Melanoma and Renal Cell Carcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2022-08-18

Completion:

2031-09-01

Conditions

• Metastatic Melanoma
• Advanced Locoregional Melanoma
• Metastatic Renal Cell Carcinoma
• Clear Cell Histology

Interventions

• DRUG

No Results Yet

NCT05150652 | COMPLETED | PHASE2

8 participants

Neoadjuvant Endocrine Therapy in ER-positive, HER2-negative Early Stage Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2022-02-18

Completion:

2025-12-09

Conditions

• Breast Cancer
• HER2-negative Breast Cancer
• Node-negative Breast Cancer
• Breast Carcinoma

Interventions

• DRUG

No Results Yet

NCT05144893 | WITHDRAWN | NA

0 participants

Brief Virtual Mindfulness-based Group Intervention With Social Support for Perinatal Individuals

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2024-05-01

Completion:

2025-07-31

Conditions

• Substance Use
• Pregnancy Related
• Mental Health

Interventions

• BEHAVIORAL

No Results Yet

NCT05129631 | COMPLETED | NA

30 participants

HEARTPrep: A Virtually-delivered Psychosocial Intervention for Mothers Expecting a Baby With Congenital Heart Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2023-07-14

Completion:

2025-05-31

Conditions

• Congenital Heart Disease

Interventions

• BEHAVIORAL

Results Available

NCT05126719 | ACTIVE_NOT_RECRUITING | PHASE2

238 participants

A Study to Evaluate the Efficacy and Safety of MRG003 in Patients With Recurrent Metastatic Nasopharyngeal Carcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2023-04-06

Completion:

2024-12-30

Conditions

• Recurrent or Metastatic Nasopharyngeal Carcinoma

Interventions

• DRUG

No Results Yet

NCT05120635 | RECRUITING | NA

80 participants

Intracranial Neurophysiological Signatures of Fear and Anxiety in Humans

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2021-10-01

Completion:

2027-05-31

Conditions

• Fear
• GAD
• Emotional Memory
• PTSD

Interventions

• DEVICE
• BEHAVIORAL

No Results Yet

NCT05112601 | RECRUITING | PHASE2

81 participants

Testing Nivolumab With or Without Ipilimumab in Deficient Mismatch Repair System (dMMR) Recurrent Endometrial Carcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2022-06-02

Completion:

2032-07-30

Conditions

• Endometrial Adenocarcinoma
• Endometrial Clear Cell Adenocarcinoma
• Endometrial Dedifferentiated Carcinoma
• Endometrial Endometrioid Adenocarcinoma
• Endometrial Mixed Cell Adenocarcinoma
• Endometrial Mucinous Adenocarcinoma
• Endometrial Undifferentiated Carcinoma
• Endometrioid Adenocarcinoma
• Recurrent Endometrial Carcinoma

Interventions

• PROCEDURE
• BIOLOGICAL

No Results Yet

NCT05092100 | ENROLLING_BY_INVITATION | NA

2900 participants

Neural Mechanisms for Reducing Interference During Episodic Memory Formation

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2021-09-29

Completion:

2026-12-31

Conditions

• Behavior

Interventions

• BEHAVIORAL
• OTHER

No Results Yet

NCT05081908 | COMPLETED | NA

25 participants

Multisession Radiosurgery in Residual/Recurrent Grade II Meningiomas.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2017-05-17

Completion:

2019-05-07

Conditions

• Meningioma Atypical

Interventions

• PROCEDURE

No Results Yet

NCT05051436 | RECRUITING | PHASE4

96 participants

The Effects of Mirabegron and Tadalafil on Glucose Tolerance in Prediabetics

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2021-12-13

Completion:

2027-01-31

Conditions

• Pre-diabetes
• Obesity

Interventions

• DRUG

No Results Yet

NCT05035030 | ACTIVE_NOT_RECRUITING | PHASE3

62 participants

Long-term Safety and Efficacy of Odevixibat in Patients With Alagille Syndrome

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2021-09-03

Completion:

2026-12-31

Conditions

• Alagille Syndrome

Interventions

• DRUG

No Results Yet

NCT05013450 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

33 participants

Dupilumab_Metastatic NSCLC

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2021-09-10

Completion:

2025-09-18

Conditions

• Metastatic Non-small Cell Lung Cancer

Interventions

• DRUG

No Results Yet

NCT04955795 | ACTIVE_NOT_RECRUITING | NA

308 participants

Telemedicine for Unhealthy Alcohol Use in Persons Living With HIV Using CETA

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2023-05-04

Completion:

2026-08-31

Conditions

• Hiv
• Alcohol Problem

Interventions

• BEHAVIORAL

No Results Yet

NCT04925063 | ACTIVE_NOT_RECRUITING | PHASE2

266 participants

The Effect of Metformin in Patients With Newly Diagnosed mHSPC

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2021-06-16

Completion:

2026-08-30

Conditions

• Metastatic Prostate Cancer

Interventions

• DRUG

No Results Yet

NCT04888923 | RECRUITING

2000 participants

Natural History of the Human Biological Response to Environmental Exposure and Injury

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-31

Start Date:

2021-11-16

Completion:

2031-12-31

Conditions

• Inflammation
• Normal Controls
• Metabolic Disease

No Results Yet

NCT04881240 | RECRUITING | PHASE1

60 participants

Study of CD19 Allogeneic Memory T-cell Therapy for Relapsed/Refractory CD19+ Leukemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2024-02-14

Completion:

2027-07-01

Conditions

• Acute Lymphoblastic Leukemia, in Relapse
• Acute Lymphoblastic Leukemia, Refractory
• Pediatric ALL

Interventions

• BIOLOGICAL
• DRUG
• DEVICE
• PROCEDURE

No Results Yet

NCT04877288 | RECRUITING | PHASE3

102 participants

A Study to Evaluate the Benefits and Risks of Conversion of Existing Adolescent Kidney Transplant Recipients Aged 12 to <18 Years to a Belatacept-based Immunosuppressive Regimen as Compared to Continuation of a Calcineurin Inhibitor-based Regimen, and Their Adherence to Immunosuppressive Medications

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2021-07-21

Completion:

2032-12-30

Conditions

• Renal Allograft Recipients

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT04868344 | COMPLETED | PHASE1

61 participants

A Study of MRG003 in Patients With Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2018-05-09

Completion:

2021-03-29

Conditions

• Advanced Solid Tumors

Interventions

• DRUG

No Results Yet

NCT04839614 | RECRUITING | NA

30 participants

Concurrent Laparoscopic Hysterectomy and Weight Loss Surgery in Obese Patients With Endometrial Carcinoma or Endometrial Intraepithelial Neoplasia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2021-08-01

Completion:

2028-06-30

Conditions

• Endometrial Carcinoma
• Obesity
• EIN
• Endometrial Intraepithelial Neoplasia
• Endometrial Cancer Stage I

Interventions

• OTHER

No Results Yet

NCT04827368 | COMPLETED

292 participants

Volatile Organic Compounds (VOCs) in Active Inflammatory Bowel Disease

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-31

Start Date:

2021-03-22

Completion:

2026-06-30

Conditions

• IBD
• Crohn Disease
• Ulcerative Colitis

Interventions

• OTHER

No Results Yet

NCT04765696 | ACTIVE_NOT_RECRUITING

1964 participants

Prospective RELOC-AGE: How Do Housing Choices and Relocation Matter for Active Ageing?

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-31

Start Date:

2021-03-01

Completion:

2028-12-31

Conditions

• Active Ageing

Interventions

• OTHER

No Results Yet

NCT04765683 | COMPLETED

220 participants

Video, Telephone or Face-to-face Surgical Consultations: a Survey of Patients' and Surgeons' Views

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-31

Start Date:

2021-08-20

Completion:

2021-10-25

Conditions

• Surgery

Interventions

• OTHER

No Results Yet

NCT04751786 | ACTIVE_NOT_RECRUITING | PHASE1

15 participants

Dose Escalation Study of Immunomodulatory Nanoparticles

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2021-01-11

Completion:

2026-12-31

Conditions

• Advanced Solid Tumor

Interventions

• DRUG

No Results Yet

NCT04736173 | ACTIVE_NOT_RECRUITING | PHASE2

169 participants

Study Evaluating Effectiveness and Safety of Zimberelimab and Domvanalimab in Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2021-02-08

Completion:

2027-05-31

Conditions

• Non Small Cell Lung Cancer
• Nonsquamous Non Small Cell Lung Cancer
• Squamous Non Small Cell Lung Cancer
• Lung Cancer

Interventions

• DRUG

No Results Yet

NCT04708470 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

55 participants

A Phase I/II Study of Combination Immunotherapy for Advanced Cancers Including HPV-Associated Malignancies, Small Bowel, and Colon Cancers

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2021-10-05

Completion:

2026-11-30

Conditions

• Oropharyngeal Cancer
• Neck Cancer
• Human Papillomavirus
• HPV
• Anal Cancer
• Cervical Cancer
• Penile Cancer
• Vulvar Cancer
• Vaginal Cancer
• Colon Cancer

Interventions

• DRUG

No Results Yet

NCT04700748 | COMPLETED | NA

150 participants

Diffusion-weighted MRI to Predict Treatment Response in Stereotactic Radiotherapy of Central Nervous System (CNS) Metastases

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2020-12-28

Completion:

2024-04-30

Conditions

• Radiotherapy
• Brain Metastases
• Sensitivity
• Radionecrosis

Interventions

• RADIATION

No Results Yet

NCT04685200 | RECRUITING

143 participants

Unraveling the Mechanisms Underlying Primary Sclerosing Cholangitis Through a Multidisciplinary, Integrative Research Approach

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-31

Start Date:

2023-03-31

Completion:

2026-10-31

Conditions

• Primary Sclerosing Cholangitis

No Results Yet

NCT04673331 | COMPLETED

50 participants

Comparison of Physical Activity, Exercise Capacity, Quality of Life, Cognitive Function and Coronavirus Phobia Levels of Adult Cystic Fibrosis Patients With Healthy Individuals With Telerehabilitation

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-31

Start Date:

2021-01-05

Completion:

2021-08-05

Conditions

• Cystic Fibrosis

Interventions

• OTHER

No Results Yet

NCT04663906 | COMPLETED

148 participants

Oral Isotretinoin and Covid-19 Infection

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-31

Start Date:

2021-01-15

Completion:

2021-09-15

Conditions

• Isotretinoin Adverse Reaction
• Covid19

No Results Yet

NCT04641351 | ACTIVE_NOT_RECRUITING | PHASE4

150 participants

Corticosteroid Meniscectomy Randomized Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2021-05-27

Completion:

2026-08-01

Conditions

• Osteoarthritis, Knee
• Meniscus Tear
• Meniscus; Degeneration
• Synovitis

Interventions

• DRUG

No Results Yet

NCT04628481 | TERMINATED | PHASE2

289 participants

A Study of Oral Ladarixin in Recent Onset Type 1 Diabetes and a Low Residual β-cell Function

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2021-01-12

Completion:

2025-03-31

Conditions

• Recent Onset type1 Diabetes

Interventions

• DRUG

Results Available

NCT04544904 | COMPLETED | NA

356 participants

The Technology, Exercise Programming, and Activity Prescription for Enhanced Mobility (TEAM) Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2021-06-18

Completion:

2026-06-01

Conditions

• Osteo Arthritis Knee
• Osteoarthritis
• Hip Arthritis

Interventions

• DEVICE

No Results Yet

NCT04538664 | ACTIVE_NOT_RECRUITING | PHASE3

308 participants

A Study of Combination Amivantamab and Carboplatin-Pemetrexed Therapy, Compared With Carboplatin-Pemetrexed, in Participants With Advanced or Metastatic Non-Small Cell Lung Cancer Characterized by Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertions

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2020-10-13

Completion:

2023-05-03

Conditions

• Carcinoma, Non-Small-Cell Lung

Interventions

• DRUG

Results Available

NCT04505371 | COMPLETED | NA

235 participants

Improving the Reach & Effectiveness of Smoking Cessation Services Targeted to Veterans Living With HIV

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2021-06-04

Completion:

2025-03-31

Conditions

• HIV Infections
• Smoking
• Smoking Cessation

Interventions

• BEHAVIORAL

Results Available

NCT04495660 | RECRUITING | NA

80 participants

Restauration of the Auditory and Cognitive Functions in Cochlear Implanted Deaf Children in fNIRS

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2020-05-29

Completion:

2027-06-03

Conditions

• Deafness

Interventions

• DEVICE
• BEHAVIORAL

No Results Yet

NCT04488536 | ACTIVE_NOT_RECRUITING

10000 participants

Management and Outcomes of Patients Admitted to Coronary Care Units, Depending on Degree of Frailty and Comorbidities

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-31

Start Date:

2020-07-29

Completion:

2021-12-31

Conditions

• Myocardial Infarction
• Frailty

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT04455334 | COMPLETED | NA

54 participants

Error-augmented Walking on Gait Performance and Brain Activities in Stroke

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2020-07-13

Completion:

2022-12-01

Conditions

• Healthy
• Stroke

Interventions

• OTHER

No Results Yet