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Clinical Trials

Showing trials with last updates posted in 2026.

NCT04034927 | ACTIVE_NOT_RECRUITING | PHASE2
61 participants

Testing the Addition of an Immunotherapy Drug, Tremelimumab, to the PARP Inhibition Drug, Olaparib, for Recurrent Ovarian, Fallopian Tube or Peritoneal Cancer

Study Type:
INTERVENTIONAL
Last Updated:
2026-08-26
Start Date:
2019-12-04
Completion:
2021-07-31
Conditions
  • Fallopian Tube Endometrioid Tumor
  • Fallopian Tube High Grade Serous Adenocarcinoma
  • Malignant Ovarian Endometrioid Tumor
  • Ovarian High Grade Serous Adenocarcinoma
  • Platinum-Sensitive Fallopian Tube Carcinoma
  • Platinum-Sensitive Ovarian Carcinoma
  • Platinum-Sensitive Primary Peritoneal Carcinoma
  • Primary Peritoneal High Grade Serous Adenocarcinoma
  • Recurrent Fallopian Tube Carcinoma
  • Recurrent Fallopian Tube Endometrioid Adenocarcinoma
  • Recurrent Ovarian Endometrioid Adenocarcinoma
  • Recurrent Ovarian Serous Adenocarcinoma
  • Recurrent Primary Peritoneal Carcinoma
  • Recurrent Primary Peritoneal Endometrioid Adenocarcinoma
Interventions
  • PROCEDURE
  • DRUG
  • BIOLOGICAL
Results Available
NCT04033302 | NOT_YET_RECRUITING | PHASE1/PHASE2
30 participants

Multi-CAR T Cell Therapy Targeting CD7-positive Malignancies

Study Type:
INTERVENTIONAL
Last Updated:
2026-08-26
Start Date:
2026-12-31
Completion:
2029-12-31
Conditions
  • T-cell Acute Lymphoblastic Leukemia
  • T-cell Acute Lymphoblastic Lymphoma
  • Acute Myeloid Leukemia
  • NK Cell Lymphoma
Interventions
  • BIOLOGICAL
No Results Yet
NCT04025879 | ACTIVE_NOT_RECRUITING | PHASE3
461 participants

A Study of Neoadjuvant Chemotherapy Plus Nivolumab Versus Neoadjuvant Chemotherapy Plus Placebo, Followed by Surgical Removal and Adjuvant Treatment With Nivolumab or Placebo for Participants With Surgically Removable Early Stage Non-small Cell Lung Cancer

Study Type:
INTERVENTIONAL
Last Updated:
2026-08-26
Start Date:
2019-11-05
Completion:
2023-07-26
Conditions
  • Carcinoma, Non-Small-Cell Lung
Interventions
  • BIOLOGICAL
  • DRUG
Results Available
NCT04016129 | NOT_YET_RECRUITING | PHASE1/PHASE2
100 participants

CAR-T Immunotherapy Targeting CD19- ALL

Study Type:
INTERVENTIONAL
Last Updated:
2026-08-26
Start Date:
2027-07-01
Completion:
2028-06-30
Conditions
  • B-cell Leukemia
Interventions
  • BIOLOGICAL
No Results Yet
NCT03961243 | NOT_YET_RECRUITING | PHASE1
10 participants

Lentiviral FIX Gene Therapy

Study Type:
INTERVENTIONAL
Last Updated:
2026-08-26
Start Date:
2027-06-01
Completion:
2028-05-31
Conditions
  • Hemophilia B
Interventions
  • BIOLOGICAL
No Results Yet
NCT03853772 | ENROLLING_BY_INVITATION
2000 participants

The Johns Hopkins Heartburn Center Registry

Study Type:
OBSERVATIONAL
Last Updated:
2026-08-26
Start Date:
2019-04-27
Completion:
2027-12-31
Conditions
  • Gastroesophageal Reflux Disease
  • Barrett Esophagus
  • Laryngopharyngeal Reflux
  • Esophagitis
No Results Yet
NCT03645486 | NOT_YET_RECRUITING | NA
10 participants

Lentiviral Gene Therapy for CGD

Study Type:
INTERVENTIONAL
Last Updated:
2026-08-26
Start Date:
2027-07-01
Completion:
2028-06-30
Conditions
  • Chronic Granulomatous Disease
Interventions
  • GENETIC
No Results Yet
NCT03632239 | ENROLLING_BY_INVITATION
1000 participants

Reverse Phenotyping Core

Study Type:
OBSERVATIONAL
Last Updated:
2026-08-26
Start Date:
2020-01-23
Completion:
2028-06-01
Conditions
  • Harboring of Unexpected Genetic Variant
No Results Yet
NCT03614650 | NOT_YET_RECRUITING | PHASE1/PHASE2
100 participants

Immunotherapy Treating GI Cancer

Study Type:
INTERVENTIONAL
Last Updated:
2026-08-26
Start Date:
2027-06-01
Completion:
2028-06-30
Conditions
  • Cancer
Interventions
  • BIOLOGICAL
No Results Yet
NCT03442556 | TERMINATED | PHASE2
18 participants

Docetaxel, Carboplatin, and Rucaparib Camsylate in Treating Patients With Metastatic Castration Resistant Prostate Cancer With Homologous Recombination DNA Repair Deficiency

Study Type:
INTERVENTIONAL
Last Updated:
2026-08-26
Start Date:
2018-08-24
Completion:
2025-06-04
Conditions
  • ATM Gene Mutation
  • BRCA1 Gene Mutation
  • BRCA2 Gene Mutation
  • Castration Levels of Testosterone
  • Castration-Resistant Prostate Carcinoma
  • Homologous Recombination Deficiency
  • Prostate Carcinoma Metastatic in the Bone
  • PSA Level Greater Than or Equal to Two
  • PSA Progression
  • Stage IV Prostate Adenocarcinoma AJCC v7
Interventions
  • DRUG
  • OTHER
Results Available
NCT03204123 | ACTIVE_NOT_RECRUITING | PHASE2
1171 participants

PSMA PET Imaging of Recurrent Prostate Cancer

Study Type:
INTERVENTIONAL
Last Updated:
2026-08-26
Start Date:
2017-06-26
Completion:
2027-06-30
Conditions
  • Prostate Adenocarcinoma
  • Prostate Cancer
Interventions
  • DRUG
  • DIAGNOSTIC_TEST
No Results Yet
NCT03173937 | RECRUITING | PHASE1/PHASE2
37 participants

Unrelated Umbilical Cord Blood Transplantation for Severe Aplastic Anemia and Hypo-plastic MDS Using CordIn(TM), Umbilical Cord Blood-Derived Ex Vivo Expanded Stem and Progenitor Cells to Expedite Engraftment and Improve Transplant Outcome

Study Type:
INTERVENTIONAL
Last Updated:
2026-08-26
Start Date:
2017-06-13
Completion:
2027-04-28
Conditions
  • Severe Aplastic Anemia
  • Hypo-Plastic MDS
  • Myelodysplastic Syndrome (MDS)
Interventions
  • BIOLOGICAL
  • DEVICE
No Results Yet
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