Clinical Trials

NCT04742387 | ACTIVE_NOT_RECRUITING

40 participants

Assessment of Bone Mineral Density in People Living With HIV and KSHV Associated Malignancies: A Retrospective Longitudinal Analysis

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-25

Start Date:

2021-02-04

Completion:

2027-12-31

Conditions

• Kaposi Sarcoma
• KSHV Associated Multicentric Castleman Disease
• Primary Effusion Lymphoma
• IL-6 Related KSHV Associated Cytokine Syndrome

No Results Yet

NCT04726241 | RECRUITING | PHASE1/PHASE2

960 participants

The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2022-04-18

Completion:

2030-12-31

Conditions

• Acute Lymphoblastic Leukemia
• Acute Myeloid Leukemia
• Acute Myeloid Leukemia Post Cytotoxic Therapy
• Juvenile Myelomonocytic Leukemia
• Mixed Phenotype Acute Leukemia
• Myelodysplastic Syndrome
• Myelodysplastic Syndrome Post Cytotoxic Therapy
• Myeloid Leukemia Associated With Down Syndrome

Interventions

• PROCEDURE

No Results Yet

NCT04721418 | ACTIVE_NOT_RECRUITING

80 participants

Aberrant Synaptic Plasticity in Cocaine Use Disorder: A 11C-UCB-J PET Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-25

Start Date:

2021-07-20

Completion:

2026-12-31

Conditions

• Cocaine Use Disorder
• Healthy Controls

Interventions

• RADIATION

No Results Yet

NCT04706663 | RECRUITING

2000 participants

Precision-Based Genomics in Prostate Cancer

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-25

Start Date:

2021-09-14

Completion:

2029-06-30

Conditions

• Prostate Cancer

No Results Yet

NCT04684368 | RECRUITING | PHASE2

160 participants

A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCT

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2021-07-13

Completion:

2029-12-21

Conditions

• Central Nervous System Nongerminomatous Germ Cell Tumor
• Choriocarcinoma
• Embryonal Carcinoma
• Immature Teratoma
• Malignant Teratoma
• Mixed Germ Cell Tumor
• Pineal Region Germ Cell Tumor
• Pineal Region Immature Teratoma
• Pineal Region Yolk Sac Tumor
• Suprasellar Germ Cell Tumor

Interventions

• PROCEDURE
• DRUG
• BIOLOGICAL
• OTHER
• RADIATION

No Results Yet

NCT04670445 | COMPLETED | NA

199 participants

Improving Patient and Caregiver Understanding of Risks and Benefits of Immunotherapy for Advanced Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2021-01-23

Completion:

2023-03-23

Conditions

• Stage IV Melanoma
• Advanced Lung Cancer
• Stage IV Non-Small Cell Lung Cancer
• Unresectable Non-Small Cell Lung Carcinoma
• Unresectable Stage III Non-Small Cell Lung Cancer
• Small Cell Lung Cancer Extensive Stage
• Stage IV Merkel Cell Carcinoma
• Stage IV Cutaneous Squamous Cell Carcinoma
• Stage IV Basal Cell Carcinoma
• Stage IV Breast Cancer
• Stage IV Colorectal Cancer
• Stage IV Gastric Cancer
• Stage IV Esophageal Cancer
• Stage IV Hepatocellular Cancer
• Stage IV Renal Cell Carcinoma
• Stage IV Bladder Cancer
• Stage IV Head and Neck Squamous Cell Carcinoma
• Stage IV Cervical Cancer
• Stage IV Endometrial Cancer
• Stage IV Mesothelioma
• Immunotherapy
• Immune Checkpoint Inhibitors

Interventions

• OTHER

No Results Yet

NCT04626791 | ACTIVE_NOT_RECRUITING | PHASE2

41 participants

Modified VR-CAP and Acalabrutinib as First Line Therapy for the Treatment of Transplant-Eligible Patients With Mantle Cell Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2021-08-03

Completion:

2025-08-03

Conditions

• Mantle Cell Lymphoma

Interventions

• DRUG
• BIOLOGICAL

Results Available

NCT04626245 | ACTIVE_NOT_RECRUITING | NA

150 participants

Mindfulness & Mechanisms Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2022-06-13

Completion:

2026-09-30

Conditions

• Hypertension in Pregnancy

Interventions

• BEHAVIORAL

No Results Yet

NCT04613596 | RECRUITING | PHASE2/PHASE3

626 participants

Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2020-12-02

Completion:

2028-10-31

Conditions

• Advanced Non-Small Cell Lung Cancer
• Metastatic Non-Small Cell Lung Cancer

Interventions

• DRUG

No Results Yet

NCT04604652 | COMPLETED | PHASE2

24 participants

Open-Label Study of HTD1801 in Adult Subjects With Primary Biliary Cholangitis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2021-05-27

Completion:

2022-05-31

Conditions

• Primary Biliary Cholangitis
• Primary Biliary Cirrhosis
• Cholangitis
• Cholestasis
• Biliary Tract Diseases
• Bile Duct Stricture

Interventions

• DRUG

Results Available

NCT04601428 | TERMINATED | EARLY_PHASE1

12 participants

Hepatic IA Therapy in Stage B or Limited Stage C Hepatoma (HCC)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2021-01-26

Completion:

2026-04-09

Conditions

• Hepatocellular Carcinoma (HCC)

Interventions

• BIOLOGICAL

No Results Yet

NCT04594993 | ACTIVE_NOT_RECRUITING

200 participants

INFINITY™ With ADAPTIS™ Technology Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-25

Start Date:

2021-02-09

Completion:

2033-11-30

Conditions

• Arthritis, Rheumatoid

Interventions

• DEVICE

No Results Yet

NCT04582383 | ACTIVE_NOT_RECRUITING | PHASE4

350 participants

Comparative Effectiveness Study of Spironolactone Versus Doxycycline for Acne

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2022-03-30

Completion:

2026-02-14

Conditions

• Acne

Interventions

• DRUG

No Results Yet

NCT04565743 | COMPLETED | NA

38 participants

Stop At One Stockholm (SAOS)- Secondary Fracture Prevention Through Active Patient Identification and Staff Education.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2018-02-01

Completion:

2025-06-10

Conditions

• Osteoporotic Fractures
• Osteoporosis
• Osteoporosis Risk

Interventions

• BEHAVIORAL

No Results Yet

NCT04557995 | RECRUITING | NA

112 participants

Erythrocytapheresis for Chronic Mountain Sickness

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2025-07-21

Completion:

2029-01-01

Conditions

• Chronic Mountain Sickness

Interventions

• PROCEDURE

No Results Yet

NCT04550715 | COMPLETED | NA

1155 participants

Prevention Interventions for Opioid Misuse

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2021-01-04

Completion:

2025-04-14

Conditions

• Opioid Use

Interventions

• BEHAVIORAL

Results Available

NCT04514367 | COMPLETED | PHASE2

28 participants

An Open Label Study of ANX005 in Participants With, or at Risk for, Manifest Huntington's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2020-09-29

Completion:

2022-08-29

Conditions

• Huntington Disease

Interventions

• DRUG

Results Available

NCT04510740 | ACTIVE_NOT_RECRUITING

1000 participants

Liver Cancer Registry Platform

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-25

Start Date:

2020-08-09

Completion:

2026-09-30

Conditions

• Hepatocellular Carcinoma (HCC)
• Cholangiocarcinoma

Interventions

• OTHER

No Results Yet

NCT04493164 | RECRUITING | PHASE2

30 participants

CPX-351 and Ivosidenib for the Treatment of IDH1 Mutated Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2020-12-30

Completion:

2028-06-01

Conditions

• Acute Myeloid Leukemia With Gene Mutations
• Myelodysplastic Syndrome
• Myeloproliferative Neoplasm
• Recurrent Acute Myeloid Leukemia
• Refractory Acute Myeloid Leukemia

Interventions

• DRUG

No Results Yet

NCT04474223 | ACTIVE_NOT_RECRUITING | PHASE3

1300 participants

Surveillance and Treatment to Prevent Fetal Atrioventricular Block Likely to Occur Quickly (STOP BLOQ)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2020-08-01

Completion:

2028-12-31

Conditions

• AVB - Atrioventricular Block
• Fetal AVB

Interventions

• DRUG

No Results Yet

NCT04419870 | RECRUITING

400 participants

Acute Infection in Mitochondrial Disease: Metabolism, Infection and Immunity

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-25

Start Date:

2020-10-21

Completion:

2027-05-01

Conditions

• Mitochondrial Disease

No Results Yet

NCT04403386 | COMPLETED

132 participants

Prospective Natural History Study of Smoking, Immune Cell Profiles, Epigenetics and COVID-19

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-25

Start Date:

2020-06-01

Completion:

2022-09-06

Conditions

• COVID-19

No Results Yet

NCT04326192 | RECRUITING | NA

10 participants

Brown Adipose Tissue Activation by Spinal Cord Stimulation

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2021-02-19

Completion:

2028-12-31

Conditions

• Pain, Back
• Obesity, Morbid
• Type 2 Diabetes

Interventions

• DEVICE

No Results Yet

NCT04322318 | RECRUITING | PHASE2

256 participants

A Study of Combination Chemotherapy for Patients With Newly Diagnosed DAWT and Relapsed FHWT

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2020-10-19

Completion:

2027-07-01

Conditions

• Anaplastic Kidney Wilms Tumor
• Recurrent Kidney Wilms Tumor
• Stage II Kidney Wilms Tumor
• Stage III Kidney Wilms Tumor
• Stage IV Kidney Wilms Tumor

Interventions

• PROCEDURE
• DRUG
• RADIATION

No Results Yet

NCT04287062 | COMPLETED | PHASE2

138 participants

Examining the Role of the Orexin System in Sleep and Stress in Persons With Opioid Use Disorder

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2020-11-20

Completion:

2025-08-15

Conditions

• Sleep Disturbance
• Opioid-use Disorder

Interventions

• DRUG

No Results Yet

NCT04243889 | ACTIVE_NOT_RECRUITING | NA

100 participants

Fetoscopic NEOX Cord 1K® Spina Bifida Repair

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2020-08-28

Completion:

2023-05-30

Conditions

• Spina Bifida
• Myelomeningocele
• Myeloschisis

Interventions

• DEVICE

Results Available

NCT04199871 | ACTIVE_NOT_RECRUITING | NA

84 participants

Improving Control of Alignment in Intermittent Exotropia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2021-03-25

Completion:

2027-06-30

Conditions

• Intermittent Exotropia

Interventions

• OTHER

No Results Yet

NCT04165798 | RECRUITING

1065 participants

KEYMAKER-U01 Umbrella Master Study: Studies of Investigational Agents With Either Pembrolizumab (MK-3475) Alone or With Pembrolizumab PLUS Chemotherapy in Participants With Non-small Cell Lung Cancer (NSCLC) (MK-3475-U01/KEYMAKER-U01)

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-25

Start Date:

2019-12-19

Completion:

2032-02-13

Conditions

• Carcinoma, Non-Small-Cell Lung

Interventions

• DIAGNOSTIC_TEST
• PROCEDURE

No Results Yet

NCT04165070 | RECRUITING | PHASE1/PHASE2

450 participants

KEYMAKER-U01 Substudy 01A: Efficacy and Safety Study of Pembrolizumab (MK-3475) With or Without Chemotherapy When Used With Investigational Agents in Treatment-naïve Participants With Stage IV Non-small Cell Lung Cancer (NSCLC) (MK-3475-01A/KEYMAKER-U01A)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2019-12-19

Completion:

2032-02-13

Conditions

• Carcinoma, Non-Small-Cell Lung

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT04133038 | COMPLETED

338 participants

Evaluation of ORALQUEST

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-25

Start Date:

2020-03-03

Completion:

2023-07-28

Conditions

• Feeding and Eating Disorders of Childhood

Interventions

• OTHER

No Results Yet

NCT04084080 | ACTIVE_NOT_RECRUITING | PHASE3

173 participants

Sickle Cell Disease and CardiovAscular Risk - Red Cell Exchange Trial (SCD-CARRE)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2020-02-26

Completion:

2026-05-11

Conditions

• Sickle Cell Disease

Interventions

• BIOLOGICAL
• OTHER

No Results Yet

NCT04048941 | TERMINATED | NA

24 participants

One Needle Hand Acupuncture for MSK Disorders

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2019-10-08

Completion:

2022-07-01

Conditions

• Acupuncture
• Pain
• Range of Motion

Interventions

• PROCEDURE

No Results Yet

NCT04039607 | COMPLETED | PHASE3

732 participants

A Study of Nivolumab in Combination With Ipilimumab in Participants With Advanced Hepatocellular Carcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2019-09-30

Completion:

2026-07-09

Conditions

• Hepatocellular Carcinoma

Interventions

• DRUG

No Results Yet

NCT04033679 | ACTIVE_NOT_RECRUITING | NA

106 participants

The Effects of Non-invasive Brain Stimulation on Treatment Adherence in Schizophrenia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2019-08-15

Completion:

2027-03-31

Conditions

• Schizophrenia;Schizoaffective

Interventions

• OTHER

No Results Yet

NCT03981640 | COMPLETED | NA

33 participants

Neural Control of Kidney Blood Flow During Exercise in African American Adults

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2024-09-30

Completion:

2026-04-30

Conditions

• Healthy

Interventions

• OTHER

No Results Yet

NCT03968900 | COMPLETED | NA

29 participants

Racial Differences in Circadian and Sleep Mechanisms for Nicotine Dependence, Craving, and Withdrawal

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2021-01-01

Completion:

2025-04-01

Conditions

• Smoking
• Sleep Disturbance
• Nicotine Dependence

Interventions

• BEHAVIORAL

Results Available

NCT03959085 | RECRUITING | PHASE3

5951 participants

Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2019-10-31

Completion:

2032-03-31

Conditions

• B Acute Lymphoblastic Leukemia
• B Lymphoblastic Lymphoma
• Central Nervous System Leukemia
• Mixed Phenotype Acute Leukemia
• Testicular Leukemia

Interventions

• PROCEDURE
• BIOLOGICAL
• DRUG
• OTHER
• RADIATION

No Results Yet

NCT03953300 | ACTIVE_NOT_RECRUITING | PHASE4

75 participants

Benralizumab Airway Remodeling Study in Severe Eosinophilic Asthmatics

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2019-10-08

Completion:

2026-10-19

Conditions

• Asthma

Interventions

• BIOLOGICAL

No Results Yet

NCT03869905 | ACTIVE_NOT_RECRUITING | PHASE2

40 participants

Aquamin® as an Adjuvant Intervention for Ulcerative Colitis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2019-08-08

Completion:

2027-12-31

Conditions

• Ulcerative Colitis

Interventions

• DRUG

No Results Yet

NCT03820947 | TERMINATED | NA

506 participants

VenaSeal Spectrum: Global Post-Market Randomized Controlled Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2020-02-05

Completion:

2024-06-12

Conditions

• Venous Reflux

Interventions

• DEVICE
• PROCEDURE

Results Available