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Clinical Trials

Showing trials with last updates posted in 2026.

NCT04165070 | RECRUITING | PHASE1/PHASE2
450 participants

KEYMAKER-U01 Substudy 01A: Efficacy and Safety Study of Pembrolizumab (MK-3475) With or Without Chemotherapy When Used With Investigational Agents in Treatment-naïve Participants With Stage IV Non-small Cell Lung Cancer (NSCLC) (MK-3475-01A/KEYMAKER-U01A)

Study Type:
INTERVENTIONAL
Last Updated:
2026-08-25
Start Date:
2019-12-19
Completion:
2032-02-13
Conditions
  • Carcinoma, Non-Small-Cell Lung
Interventions
  • BIOLOGICAL
  • DRUG
No Results Yet
NCT04133038 | COMPLETED
338 participants

Evaluation of ORALQUEST

Study Type:
OBSERVATIONAL
Last Updated:
2026-08-25
Start Date:
2020-03-03
Completion:
2023-07-28
Conditions
  • Feeding and Eating Disorders of Childhood
Interventions
  • OTHER
No Results Yet
NCT03959085 | RECRUITING | PHASE3
5951 participants

Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy

Study Type:
INTERVENTIONAL
Last Updated:
2026-08-25
Start Date:
2019-10-31
Completion:
2032-03-31
Conditions
  • B Acute Lymphoblastic Leukemia
  • B Lymphoblastic Lymphoma
  • Central Nervous System Leukemia
  • Mixed Phenotype Acute Leukemia
  • Testicular Leukemia
Interventions
  • PROCEDURE
  • BIOLOGICAL
  • DRUG
  • OTHER
  • RADIATION
No Results Yet
NCT03630991 | RECRUITING | PHASE1
58 participants

Edetate Calcium Disodium or Succimer in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome Undergoing Chemotherapy

Study Type:
INTERVENTIONAL
Last Updated:
2026-08-25
Start Date:
2018-10-11
Completion:
2027-04-30
Conditions
  • Acute Myeloid Leukemia
  • Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome
  • Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive
  • Chronic Myelogenous Leukemia, BCR-ABL1 Positive
  • High Risk Myelodysplastic Syndrome
  • Myelodysplastic Syndrome
  • Myelodysplastic/Myeloproliferative Neoplasm
  • Myeloproliferative Neoplasm
  • Recurrent Acute Myeloid Leukemia
  • Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive
  • Recurrent Myelodysplastic Syndrome
  • Recurrent Myelodysplastic/Myeloproliferative Neoplasm
  • Refractory Acute Myeloid Leukemia
  • Refractory Chronic Myelogenous Leukemia, BCR-ABL1 Positive
  • Refractory Myelodysplastic Syndrome
  • Secondary Acute Myeloid Leukemia
  • Secondary Myelodysplastic Syndrome
  • Very High Risk Myelodysplastic Syndrome
Interventions
  • DRUG
  • DIETARY_SUPPLEMENT
No Results Yet
NCT03533582 | ACTIVE_NOT_RECRUITING | PHASE3
537 participants

Cisplatin and Combination Chemotherapy in Treating Children and Young Adults With Hepatoblastoma or Liver Cancer After Surgery

Study Type:
INTERVENTIONAL
Last Updated:
2026-08-25
Start Date:
2018-05-24
Completion:
2027-03-31
Conditions
  • Childhood Hepatocellular Carcinoma
  • Childhood Malignant Liver Neoplasm
  • Fibrolamellar Carcinoma
  • Hepatoblastoma
  • Hepatocellular Malignant Neoplasm, Not Otherwise Specified
Interventions
  • PROCEDURE
  • DRUG
  • OTHER
No Results Yet
NCT03312465 | ACTIVE_NOT_RECRUITING
73 participants

Anatomical Shoulder Domelock System Study

Study Type:
OBSERVATIONAL
Last Updated:
2026-08-25
Start Date:
2017-09-28
Completion:
2032-12-09
Conditions
  • Avascular Necrosis
  • Revision Surgery
  • Conditions Consequent to Earlier Operations
  • Arthritis, Rheumatoid
  • Arthritis, Degenerative
  • Arthritis;Traumatic
Interventions
  • DEVICE
No Results Yet
NCT03304639 | COMPLETED | PHASE2
9 participants

Testing the Addition of Radiation Therapy to Immunotherapy for Merkel Cell Carcinoma

Study Type:
INTERVENTIONAL
Last Updated:
2026-08-25
Start Date:
2018-06-12
Completion:
2022-06-07
Conditions
  • Advanced Merkel Cell Carcinoma
  • Clinical Stage III Cutaneous Merkel Cell Carcinoma AJCC v8
  • Clinical Stage IV Cutaneous Merkel Cell Carcinoma AJCC v8
  • Metastatic Merkel Cell Carcinoma
  • Pathologic Stage III Cutaneous Merkel Cell Carcinoma AJCC v8
  • Pathologic Stage IIIA Cutaneous Merkel Cell Carcinoma AJCC v8
  • Pathologic Stage IIIB Cutaneous Merkel Cell Carcinoma AJCC v8
  • Pathologic Stage IV Cutaneous Merkel Cell Carcinoma AJCC v8
Interventions
  • BIOLOGICAL
  • RADIATION
Results Available
NCT03067181 | RECRUITING | PHASE3
1780 participants

Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors

Study Type:
INTERVENTIONAL
Last Updated:
2026-08-25
Start Date:
2017-05-25
Completion:
2027-06-30
Conditions
  • Childhood Extracranial Germ Cell Tumor
  • Extragonadal Embryonal Carcinoma
  • Germ Cell Tumor
  • Malignant Germ Cell Tumor
  • Malignant Ovarian Teratoma
  • Stage I Ovarian Choriocarcinoma
  • Stage I Ovarian Embryonal Carcinoma AJCC v6 and v7
  • Stage I Ovarian Yolk Sac Tumor AJCC v6 and v7
  • Stage I Testicular Choriocarcinoma AJCC v6 and v7
  • Stage I Testicular Embryonal Carcinoma AJCC v6 and v7
  • Stage I Testicular Seminoma AJCC v6 and v7
  • Stage I Testicular Yolk Sac Tumor AJCC v6 and v7
  • Stage II Ovarian Choriocarcinoma
  • Stage II Ovarian Embryonal Carcinoma AJCC v6 and v7
  • Stage II Ovarian Yolk Sac Tumor AJCC v6 and v7
  • Stage II Testicular Choriocarcinoma AJCC v6 and v7
  • Stage II Testicular Embryonal Carcinoma AJCC v6 and v7
  • Stage II Testicular Yolk Sac Tumor AJCC v6 and v7
  • Stage III Ovarian Choriocarcinoma
  • Stage III Ovarian Embryonal Carcinoma AJCC v6 and v7
  • Stage III Ovarian Yolk Sac Tumor AJCC v6 and v7
  • Stage III Testicular Choriocarcinoma AJCC v6 and v7
  • Stage III Testicular Embryonal Carcinoma AJCC v6 and v7
  • Stage III Testicular Yolk Sac Tumor AJCC v6 and v7
  • Stage IV Ovarian Choriocarcinoma
  • Stage IV Ovarian Embryonal Carcinoma AJCC v6 and v7
  • Stage IV Ovarian Yolk Sac Tumor AJCC v6 and v7
  • Testicular Mixed Choriocarcinoma and Embryonal Carcinoma
  • Testicular Mixed Choriocarcinoma and Teratoma
  • Testicular Mixed Choriocarcinoma and Yolk Sac Tumor
Interventions
  • OTHER
  • PROCEDURE
  • BIOLOGICAL
  • DRUG
No Results Yet
NCT02568267 | ACTIVE_NOT_RECRUITING | PHASE2
534 participants

Basket Study of Entrectinib (RXDX-101) for the Treatment of Patients With Solid Tumors Harboring NTRK 1/2/3 (Trk A/B/C), ROS1, or ALK Gene Rearrangements (Fusions)

Study Type:
INTERVENTIONAL
Last Updated:
2026-08-25
Start Date:
2015-11-19
Completion:
2027-06-30
Conditions
  • Breast Cancer
  • Cholangiocarcinoma
  • Colorectal Cancer
  • Head and Neck Neoplasms
  • Lymphoma, Large-Cell, Anaplastic
  • Melanoma
  • Neuroendocrine Tumors
  • Non-Small Cell Lung Cancer
  • Ovarian Cancer
  • Pancreatic Cancer
  • Papillary Thyroid Cancer
  • Primary Brain Tumors
  • Renal Cell Carcinoma
  • Sarcomas
  • Salivary Gland Cancers
  • Adult Solid Tumor
Interventions
  • DRUG
No Results Yet
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