AZD1775 in Women With Recurrent or Persistent Uterine Serous Carcinoma or Uterine Carcinosarcoma
NCT03668340 · Status: ACTIVE_NOT_RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 49
Last updated 2026-01-12
Summary
This research study is studying an investigational drug as a possible treatment for uterine cancer.
The drug involved in this study is:
-AZD1775
Conditions
- Uterine Cancer
Interventions
- DRUG
-
AZD1775
AZD1775 blocks the activity of Wee1, a protein that helps to regulate how cells divide and grow. Certain cancer cells may be more vulnerable to having this process blocked
Sponsors & Collaborators
- collaborator INDUSTRY
- lead OTHER
Principal Investigators
-
Joyce Liu, MD · Dana-Farber Cancer Institute
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2018-10-22
- Primary Completion
- 2026-07-01
- Completion
- 2027-07-01
- FDA Drug
- Yes
Countries
- United States
Study Locations
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