Clinical Trials

NCT04008030 | ACTIVE_NOT_RECRUITING | PHASE3

839 participants

A Study of Nivolumab, Nivolumab Plus Ipilimumab, or Investigator's Choice Chemotherapy for the Treatment of Participants With Deficient Mismatch Repair (dMMR)/Microsatellite Instability High (MSI-H) Metastatic Colorectal Cancer (mCRC)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2019-08-05

Completion:

2024-08-28

Conditions

• Metastatic Colorectal Cancer

Interventions

• BIOLOGICAL
• DRUG

Results Available

NCT04007029 | ACTIVE_NOT_RECRUITING | PHASE1

24 participants

Modified Immune Cells (CD19/CD20 CAR-T Cells) in Treating Patients With Recurrent or Refractory B-Cell Lymphoma or Chronic Lymphocytic Leukemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2019-10-04

Completion:

2027-08-01

Conditions

• CD19 Positive
• CD20 Positive
• Recurrent Chronic Lymphocytic Leukemia
• Recurrent Diffuse Large B-Cell Lymphoma
• Recurrent Follicular Lymphoma
• Recurrent Mantle Cell Lymphoma
• Recurrent Primary Mediastinal (Thymic) Large B-Cell Cell Lymphoma
• Recurrent Small Lymphocytic Lymphoma
• Refractory Chronic Lymphocytic Leukemia
• Refractory Diffuse Large B-Cell Lymphoma
• Refractory Follicular Lymphoma
• Refractory Mantle Cell Lymphoma
• Refractory Primary Mediastinal (Thymic) Large B-Cell Cell Lymphoma
• Refractory Small Lymphocytic Lymphoma

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT04001582 | RECRUITING

1018 participants

The United Kingdom Facioscapulohumeral Muscular Dystrophy Patient Registry

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-20

Start Date:

2013-05-31

Completion:

2040-01-31

Conditions

• Facioscapulohumeral Muscular Dystrophy

Interventions

• OTHER

No Results Yet

NCT03971422 | COMPLETED | PHASE3

200 participants

A Study to Test Efficacy and Safety of Rozanolixizumab in Adult Patients With Generalized Myasthenia Gravis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2019-06-03

Completion:

2021-08-31

Conditions

• Generalized Myasthenia Gravis

Interventions

• DRUG
• OTHER

Results Available

NCT03964454 | COMPLETED | NA

168 participants

BOOST: Breastfeeding Onset and Onward With Support Tools

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2019-06-19

Completion:

2023-04-18

Conditions

• Breastfeeding Duration

Interventions

• BEHAVIORAL

Results Available

NCT03954678 | RECRUITING | NA

400 participants

Exercise in Patients Undergoing Urologic Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2019-07-30

Completion:

2028-07-31

Conditions

• Perioperative Complication

Interventions

• BEHAVIORAL
• DIETARY_SUPPLEMENT

No Results Yet

NCT03933904 | ACTIVE_NOT_RECRUITING | PHASE2

7 participants

Sirolimus in Previously Treated Idiopathic Multicentric Castleman Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2019-09-25

Completion:

2024-06-30

Conditions

• Castleman Disease
• Castleman's Disease, Multicentric

Interventions

• DRUG

Results Available

NCT03932773 | RECRUITING | NA

330 participants

Multi-site Confirmatory Efficacy Treatment Trial of Combat-related PTSD

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2019-05-01

Completion:

2028-01-01

Conditions

• Post Traumatic Stress Disorder

Interventions

• DEVICE
• BEHAVIORAL

No Results Yet

NCT03915899 | COMPLETED | NA

9080 participants

The Welcome Incoming Neighbor (WIN) Community Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2019-05-01

Completion:

2025-07-01

Conditions

• HIV

Interventions

• BEHAVIORAL

No Results Yet

NCT03911700 | ACTIVE_NOT_RECRUITING | NA

477 participants

Prophylactic Reinforcement of Ventral Abdominal Incisions Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2019-12-12

Completion:

2028-08-31

Conditions

• Open Midline Laparotomy

Interventions

• DEVICE

No Results Yet

NCT03898804 | RECRUITING | NA

12 participants

An Early Feasibility Study of the ReHAB System

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2019-04-09

Completion:

2029-08-01

Conditions

• Tetraplegia

Interventions

• DEVICE

No Results Yet

NCT03845218 | COMPLETED

49 participants

Retinitis Pigmentosa Clinical Measures and Repeatability Testing of Potential Outcome Measures

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-20

Start Date:

2019-09-27

Completion:

2023-07-19

Conditions

• Retinitis Pigmentosa

No Results Yet

NCT03811964 | RECRUITING | NA

726 participants

Photomotor Reflex to Evaluate the Role of the Non-visual Effects of Light in Neurological, Psychiatric and Ophthalmological Pathologies

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2020-01-22

Completion:

2028-01-31

Conditions

• Sleep Disorders
• Neurological Pathologies
• Psychiatric Pathologies
• Ophthalmological Pathologies

Interventions

• OTHER

No Results Yet

NCT03785964 | COMPLETED | PHASE3

142 participants

Nirogacestat for Adults With Desmoid Tumor/Aggressive Fibromatosis (DT/AF)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2019-04-17

Completion:

2022-04-07

Conditions

• Desmoid Tumor
• Aggressive Fibromatosis

Interventions

• DRUG

Results Available

NCT03752892 | ACTIVE_NOT_RECRUITING | NA

50 participants

Partitioned Training of Patients With Idiopathic Pulmonary Fibrosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2019-03-01

Completion:

2025-04-28

Conditions

• Lung; Disease, Interstitial, With Fibrosis

Interventions

• OTHER

No Results Yet

NCT03682068 | ACTIVE_NOT_RECRUITING | PHASE3

1246 participants

Study of Durvalumab Given With Chemotherapy, Durvalumab in Combination With Tremelimumab Given With Chemotherapy, or Chemotherapy in Patients With Unresectable Urothelial Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2018-09-27

Completion:

2026-06-01

Conditions

• Unresectable Locally Advanced Urothelial Cancer
• Metastatic Urothelial Cancer

Interventions

• DRUG

No Results Yet

NCT03675412 | RECRUITING | NA

80 participants

Caffeine Consumption in Glaucoma Patients and Healthy Subjects

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2018-12-30

Completion:

2027-04-30

Conditions

• Glaucoma, Primary Open Angle

Interventions

• DIETARY_SUPPLEMENT

No Results Yet

NCT03661307 | RECRUITING | PHASE1/PHASE2

73 participants

Quizartinib, Decitabine, and Venetoclax in Treating Participants With Untreated or Relapsed Acute Myeloid Leukemia or High Risk Myelodysplastic Syndrome

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2018-10-31

Completion:

2028-01-01

Conditions

• Acute Myeloid Leukemia
• Myelodysplastic Syndrome
• Recurrent Acute Myeloid Leukemia
• Recurrent Myelodysplastic Syndrome
• Refractory Acute Myeloid Leukemia

Interventions

• DRUG

No Results Yet

NCT03636152 | COMPLETED | PHASE2

100 participants

Management of Cardiovascular Disease in Kidney Disease (MaCK) Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2018-12-14

Completion:

2024-01-31

Conditions

• Chronic Kidney Disease
• Cardiovascular Disease
• Inflammation
• Atherosclerosis
• Aortic Stiffness

Interventions

• PROCEDURE
• DRUG

Results Available

NCT03621670 | COMPLETED | PHASE3

1196 participants

Safety and Immunogenicity of GSK Meningococcal Group B Vaccine and 13-valent Pneumococcal Vaccine Administered Concomitantly With Routine Infant Vaccines to Healthy Infants

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2018-07-27

Completion:

2024-12-27

Conditions

• Infections, Meningococcal

Interventions

• BIOLOGICAL

Results Available

NCT03603223 | RECRUITING | PHASE2

26 participants

Pembrolizumab in Treating Participants With Leukoplakia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2019-05-03

Completion:

2027-08-01

Conditions

• Erythroleukoplakia
• Leukoplakia
• Verrucous Oral Leukoplakia

Interventions

• BIOLOGICAL

No Results Yet

NCT03511586 | RECRUITING

2500 participants

Total Shoulder Arthroplasty Multi-Center Registry

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-20

Start Date:

2015-07-28

Completion:

2035-07-31

Conditions

• Shoulder Arthroplasty

No Results Yet

NCT03494738 | COMPLETED

600 participants

Development of an Epigenetic Biomarker for Prediction of Fetal Alcohol Spectrum Disorder

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-20

Start Date:

2018-04-12

Completion:

2022-12-31

Conditions

• Fetal Alcohol Spectrum Disorders

No Results Yet

NCT03472599 | COMPLETED | NA

17 participants

Chronic Electrical Stimulation to Reduce Bladder Hyperreflexia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2019-11-01

Completion:

2023-09-30

Conditions

• Neurogenic Bladder Dysfunction

Interventions

• OTHER

Results Available

NCT03471260 | RECRUITING | PHASE1/PHASE2

96 participants

Ivosidenib and Venetoclax With or Without Azacitidine in Treating Patients With IDH1 Mutated Hematologic Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2018-03-19

Completion:

2027-09-30

Conditions

• Acute Myeloid Leukemia
• Hematopoietic and Lymphoid System Neoplasm
• Myelodysplastic Syndrome
• Myeloproliferative Neoplasm
• Recurrent Acute Myeloid Leukemia
• Refractory Acute Myeloid Leukemia

Interventions

• DRUG

No Results Yet

NCT03368092 | RECRUITING | PHASE3

500 participants

Inhaled Dornase Alpha to Reduce Respiratory Failure After Severe Trauma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2019-03-04

Completion:

2027-09-01

Conditions

• Multiple Trauma
• Respiratory Distress Syndrome, Adult

Interventions

• DRUG

No Results Yet

NCT03355976 | ACTIVE_NOT_RECRUITING | PHASE2

46 participants

BrUOG 354 Nivolumab +/- Ipilimumab for Ovarian and Extra-renal Clear Cell Carcinomas

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2018-04-30

Completion:

2026-10-31

Conditions

• Ovarian Cancer
• Fallopian Tube Cancer
• Primary Peritoneal Carcinoma
• Extra Renal Origin
• Clear Cell Adenocarcinoma

Interventions

• DRUG

No Results Yet

NCT03291470 | COMPLETED | PHASE3

531 participants

Study to Determine the Efficacy and Safety of TG-C in Subjects With Kellgren/Lawrence Grade 2 or 3 OA of the Knee

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2021-12-09

Completion:

2024-03-06

Conditions

• Degenerative Osteoarthritis

Interventions

• BIOLOGICAL

No Results Yet

NCT03274258 | TERMINATED | PHASE2

10 participants

Phase II Trial of Nivolumab Plus Ipilimumab in Patients With Renal Medullary Carcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2018-05-29

Completion:

2025-11-21

Conditions

• Kidney Medullary Carcinoma
• Loss of INI 1 Protein Expression
• Stage III Renal Cell Cancer AJCC v8
• Stage IV Renal Cell Cancer AJCC v8

Interventions

• BIOLOGICAL

Results Available

NCT03217006 | RECRUITING | NA

4300 participants

Randomization of Single vs Multiple Arterial Grafts

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2018-01-07

Completion:

2029-12-31

Conditions

• Coronary Artery Disease
• Heart Diseases

Interventions

• PROCEDURE

No Results Yet

NCT03203330 | ACTIVE_NOT_RECRUITING | PHASE3

535 participants

A Study to Determine the Safety and Efficacy of TG-C in Subjects With Kellgren and Lawrence Grade 2 or 3 OA of the Knee

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2018-10-30

Completion:

2024-07-10

Conditions

• Degenerative Osteoarthritis

Interventions

• BIOLOGICAL

No Results Yet

NCT03148106 | TERMINATED | NA

14 participants

Hand Rehabilitation Study for Stroke Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2017-04-04

Completion:

2025-12-02

Conditions

• Upper Extremity Paresis
• Disability Physical
• Chronic Stroke
• Motor Disorders

Interventions

• DEVICE

No Results Yet

NCT03076697 | COMPLETED

472 participants

Smartphone Screening for Eye Diseases

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-20

Start Date:

2015-04-16

Completion:

2019-05-15

Conditions

• Diabetes Mellitus
• Glaucoma
• Age Related Macular Degeneration
• ROP
• Diabetic Retinopathy
• Retinal Disease

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT02939573 | RECRUITING | PHASE2

90 participants

A Randomized Multicenter Study for Isolated Skin Vasculitis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2017-01-01

Completion:

2028-12-31

Conditions

• Primary Cutaneous Vasculitis
• Cutaneous Polyarteritis Nodosa
• IgA Vasculitis
• Henoch-Schönlein Purpura

Interventions

• DRUG

No Results Yet

NCT02879695 | ACTIVE_NOT_RECRUITING | PHASE1

28 participants

Blinatumomab and Nivolumab With or Without Ipilimumab in Treating Patients With Poor-Risk Relapsed or Refractory CD19+ Precursor B-Lymphoblastic Leukemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2017-10-25

Completion:

2023-05-22

Conditions

• Recurrent B Acute Lymphoblastic Leukemia
• Recurrent Mixed Phenotype Acute Leukemia
• Refractory B Acute Lymphoblastic Leukemia
• Refractory Mixed Phenotype Acute Leukemia

Interventions

• PROCEDURE
• BIOLOGICAL

Results Available

NCT02835222 | ACTIVE_NOT_RECRUITING | PHASE2

57 participants

Selinexor With Combination With Induction/Consolidation Therapy in Acute Myeloid Leukemia Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2018-02-02

Completion:

2027-04-18

Conditions

• Untreated Adult Acute Myeloid Leukemia

Interventions

• DRUG

No Results Yet

NCT02767973 | SUSPENDED | NA

160 participants

To Identify Persons Who Are Susceptible to WSP-induced Inflammation and Examine the Role of GSTM1 and Other Factors in This Susceptibility

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2016-06-09

Completion:

2027-05-31

Conditions

• Airway Inflammation
• Allergic Asthma

Interventions

• OTHER

No Results Yet

NCT02728076 | ACTIVE_NOT_RECRUITING | NA

39 participants

MRI-Based Preoperative Accelerated Partial Breast Irradiation

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2016-07-29

Completion:

2021-09-16

Conditions

• Breast Cancer

Interventions

• RADIATION

Results Available

NCT02661386 | COMPLETED | NA

32 participants

Esophageal Manometry During Recovery From Anesthesia: Pilot Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2016-01-31

Completion:

2019-03-05

Conditions

• Motility Function

Interventions

• DEVICE

Results Available

NCT02658279 | ACTIVE_NOT_RECRUITING | NA

27 participants

Pembrolizumab (MK-3475) in Patients With Recurrent Malignant Glioma With a Hypermutator Phenotype

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-20

Start Date:

2016-01-22

Completion:

2027-01-31

Conditions

• Glioma
• Recurrent Malignant Glioma

Interventions

• DRUG

No Results Yet