Trial Outcomes & Findings for Esophageal Manometry During Recovery From Anesthesia: Pilot Study (NCT NCT02661386)
NCT ID: NCT02661386
Last Updated: 2026-08-20
Results Overview
Our primary objective is to determine the timing of the return of normal pharyngoesophageal function upon withdrawal of general anesthesia.
COMPLETED
NA
32 participants
From withdrawal of general anesthesia until the return of normal pharyngoesophageal function, assessed up to 40 minutes.
2026-08-20
Participant Flow
Participant milestones
| Measure |
Manometry Device
Motility Procedure: The use of esophageal manometry device during general anesthesia. During the last 10 minutes of subjects "waking up" from anesthesia, the motility procedure will be performed.
|
|---|---|
|
Overall Study
STARTED
|
32
|
|
Overall Study
COMPLETED
|
32
|
|
Overall Study
NOT COMPLETED
|
0
|
Reasons for withdrawal
Withdrawal data not reported
Baseline Characteristics
Race and Ethnicity were not collected from any participant.
Baseline characteristics by cohort
| Measure |
Manometry Device
n=32 Participants
During the last 10 minutes of subjects "waking up" from anesthesia, the motility procedure will be performed.
Motility Procedure: The use of esophageal manometry device during general anesthesia
|
|---|---|
|
Age, Categorical
<=18 years
|
0 Participants
n=32 Participants
|
|
Age, Categorical
Between 18 and 65 years
|
27 Participants
n=32 Participants
|
|
Age, Categorical
>=65 years
|
5 Participants
n=32 Participants
|
|
Sex: Female, Male
Female
|
18 Participants
n=32 Participants
|
|
Sex: Female, Male
Male
|
14 Participants
n=32 Participants
|
PRIMARY outcome
Timeframe: From withdrawal of general anesthesia until the return of normal pharyngoesophageal function, assessed up to 40 minutes.Population: Thirty-two patients, 18 women and 14 men, ages ranging from 20 to 76 years were studied.
Our primary objective is to determine the timing of the return of normal pharyngoesophageal function upon withdrawal of general anesthesia.
Outcome measures
| Measure |
Manometry Device
n=32 Participants
During the last 10 minutes of subjects "waking up" from anesthesia, esophageal manometry will be evaluated
|
|---|---|
|
Total Time of the Return of Normal Pharyngoesophageal Function
|
12.40 minutes
Interval 5.17 to 36.57
|
SECONDARY outcome
Timeframe: From withdrawal of general anesthesia until the return of normal pharyngoesophageal function, assessed up to 40 minutes.Population: Thirty-two patients, 18 women and 14 men, ages ranging from 20 to 76 years were studied.
Correlation of the return of normal pharyngoesophageal function with other markers generally used by Anesthesia staff to indicate a safe time for removal of endotracheal tubes.
Outcome measures
| Measure |
Manometry Device
n=32 Participants
During the last 10 minutes of subjects "waking up" from anesthesia, esophageal manometry will be evaluated
|
|---|---|
|
Number of Participants With Normal Pharyngoesophageal Function.
|
32 Participants
|
Adverse Events
Manometry Device
Serious adverse events
Adverse event data not reported
Other adverse events
Adverse event data not reported
Additional Information
Dr. John P. Cello, Professor Emeritus of Medicine and Surgery
University of California, San Francisco
Results disclosure agreements
- Principal investigator is a sponsor employee
- Publication restrictions are in place