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Photomotor Reflex to Evaluate the Role of the Non-visual Effects of Light in Neurological, Psychiatric and Ophthalmological Pathologies

NCT03811964 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 726

Last updated 2025-08-08

No results posted yet for this study

Summary

The light has visual and non-visual effects on organism and can act on the behavior, the mood, the cognition and the sleep. These effects are mediated by "classical" retina photoreceptors which allow vision (rods, cones) but also melanopsin cells. The non-visual effects of light seems to be altered in many neurological, psychiatric or ophtalmological conditions but their exact role in the pathogenesis remains poorly understand. The purpose of the study is to increase our knowledge of the non-visual effects of light and establish new therapeutic applications

Conditions

  • Sleep Disorders
  • Neurological Pathologies
  • Psychiatric Pathologies
  • Ophthalmological Pathologies

Interventions

OTHER

Specific light exposures

Specific light exposures using light in a wide range of intensities or different light/dark regimens

Sponsors & Collaborators

  • University Hospital, Strasbourg, France

    lead OTHER

Principal Investigators

  • Bourgin Patrice, MD · University Hospital, Strasbourg, France

Study Design

Allocation
NON_RANDOMIZED
Purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2020-01-22
Primary Completion
2027-01-31
Completion
2027-02-28

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03811964 on ClinicalTrials.gov