Clinical Trials Updated in 2026

NCT06922032 | NOT_YET_RECRUITING | NA

20 participants

A Novel Auditory Application for Distraction in Pediatric Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2026-12-01
Completion:: 2028-01-30

Conditions

Emotional Distress

Interventions

DEVICE

No Results Yet

NCT06920628 | RECRUITING | PHASE1

60 participants

PET Imaging of Cyclooxygenase-1 in Participants With Neurological Manifestations of Post-Acute Sequelae of SARS-CoV-2 Infection (PASC)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2025-06-18
Completion:: 2028-02-22

Conditions

Long COVID
Post Acute Sequelae of COVID-19

Interventions

DRUG

No Results Yet

NCT06910072 | ENROLLING_BY_INVITATION | PHASE2/PHASE3

32 participants

Paclitaxel Polymeric Micelles and Carboplatin in Combination With Iparomilimab and Tuvonralimab Neoadjuvant Therapy for Triple-negative Breast Cancer（UPGRADE-TNBC）

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2025-07-21
Completion:: 2027-06-01

Conditions

Triple-Negative Breast Cancer (TNBC)
Neoadjuvant Therapy

Interventions

DRUG

No Results Yet

NCT06909344 | COMPLETED | NA

50 participants

577-nm Diode Laser in the Treatment of Non -Inflammatory Acne

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2025-03-29
Completion:: 2025-11-01

Conditions

Acne

Interventions

DEVICE

No Results Yet

NCT06905288 | RECRUITING

70 participants

Real-world Study on Secukinumab Effectiveness in Biologic-naïve Ankylosing Spondylitis (AS) Patients in Korea.

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-18
Start Date:: 2025-04-02
Completion:: 2026-12-31

Conditions

Ankylosing Spondylitis

Interventions

DRUG

No Results Yet

NCT06904911 | RECRUITING | PHASE2

20 participants

Intra-Arterial Tenecteplase to Improve the Microvascular Hemodynamics After Mechanical Thrombectomy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2026-02-13
Completion:: 2026-12-30

Conditions

Acute Ischemic Stroke From Large Vessel Occlusion

Interventions

DRUG

No Results Yet

NCT06903676 | COMPLETED | NA

50 participants

Utility of Trypsinogen -2 in Early Detection and Follow Up of Post-pancreatectomy Acute Pancreatitis (PPAP)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2025-08-05
Completion:: 2026-04-02

Conditions

Pancreatitis
Pancreatectomy

Interventions

DEVICE

No Results Yet

NCT06888388 | RECRUITING

4700 participants

Long-term Safety of Nipple Sparing Mastectomy in Women With High Penetrance Breast Cancer Susceptibility Genes in Breast Cancer

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-18
Start Date:: 2025-02-01
Completion:: 2027-02-01

Conditions

Breast Cancer Surgery

Interventions

PROCEDURE

No Results Yet

NCT06874374 | COMPLETED | NA

40 participants

Individualized Non-invasive Brain Stimulation for the Treatment of Major Depressive Disorder

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2025-04-11
Completion:: 2026-05-22

Conditions

Depression - Major Depressive Disorder
Transcranial Alternating Current Stimulation

Interventions

DEVICE

No Results Yet

NCT06874205 | RECRUITING | PHASE1

40 participants

Assessment of 11C-JMJ-129 for Imaging PDE4D in Brain and Whole Body of Healthy Volunteers

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2025-04-11
Completion:: 2028-02-22

Conditions

Healthy

Interventions

DRUG

No Results Yet

NCT06860984 | RECRUITING | PHASE3

44 participants

Evaluating the Safety and Efficacy of Duloxetine in the Prevention of Post Endoscopic Retrograde Cholangiopancreatography Pancreatitis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2025-03-10
Completion:: 2027-06-20

Conditions

Biliary Disease

Interventions

DRUG
OTHER

No Results Yet

NCT06857565 | COMPLETED | NA

84 participants

Study to Evaluate the Efficacy of Lactobacillus Crispatus M247 in the Prevention of Recurrent Urinary Tract Infections

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2025-03-05
Completion:: 2026-04-11

Conditions

Recurrent Urinary Tract Infection

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT06855732 | ACTIVE_NOT_RECRUITING | NA

204 participants

Pain Self-Management and Treatment Engagement for Patients Taking Opioids

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2024-11-25
Completion:: 2026-08-31

Conditions

Chronic Pain
Opioid Use Disorder
Opioid Misuse and Addiction

Interventions

BEHAVIORAL

No Results Yet

NCT06855329 | RECRUITING

500 participants

PRospective phenotypIng and Multi-omic Endotyping of Progressive Pulmonary Fibrosis

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-18
Start Date:: 2025-05-01
Completion:: 2029-12-31

Conditions

Progressive Pulmonary Fibrosis
Interstitial Lung Disease

No Results Yet

NCT06850402 | RECRUITING | NA

400 participants

Evaluation of a Novel Optical Microscope With a Deep Depth of Field (DeepDOF) to Provide Histologic-quality Images on Cervical Biopsies and Loop Electrosurgical Excision Procedure (LEEP) Specimens at the Point-of-care

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2025-09-22
Completion:: 2027-09-01

Conditions

Cervical Cancer
HIV

Interventions

DEVICE

No Results Yet

NCT06846996 | RECRUITING

260 participants

Real-world Effectiveness and Safety of Trastuzumab Deruxtecan in Patients With Locally Advanced or Metastatic HER2-positive Gastric or Gastroesophageal Junction Adenocarcinoma in China

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-18
Start Date:: 2025-02-27
Completion:: 2027-07-31

Conditions

HER2-positive Gastric Cancer
HER2-positive Gastroesophageal Junction

Interventions

DRUG

No Results Yet

NCT06841796 | ACTIVE_NOT_RECRUITING | NA

84 participants

The YMCA Healthy Lifestyle Program for Prediabetes

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2025-02-17
Completion:: 2026-10-31

Conditions

PreDiabetes

Interventions

DEVICE

No Results Yet

NCT06835829 | ACTIVE_NOT_RECRUITING | NA

480 participants

Comparing Advanced Hemostasis and Ultrasound-Guided Puncture to Conventional Approaches in Distal Radial Access

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2025-12-31
Completion:: 2026-07-30

Conditions

Coronary Catheterization

Interventions

DEVICE
PROCEDURE

No Results Yet

NCT06826079 | RECRUITING | PHASE2

86 participants

Safety and Efficacy Study of Sorbitol With Neoadjuvant Chemotherapy Combined With Tirellizumab (PD-1 Inhibitor) in Patients With Locally Advanced Gastric Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2024-11-01
Completion:: 2028-08-01

Conditions

Gastric Junction Adenocarcinoma
Gastric Cancer
Immunotherapy
Neoadjuvant Therapies

Interventions

DRUG

No Results Yet

NCT06822049 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

200 participants

Remote vs. In-Person Study Evaluation (RISE) Trials: RISE Above Smoking (Trial 1)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2025-03-10
Completion:: 2026-08-31

Conditions

Remote vs. In-Person
Remote Visits
In-person Visits

Interventions

DRUG

No Results Yet

NCT06810934 | RECRUITING | PHASE1/PHASE2

80 participants

A Phase 1/2A, Randomized Study of a T Follicular Helper (TFH)-Targeting Genetic Vaccine Strategy Designed to Induce Broad, Durable Immune Responses

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2025-10-21
Completion:: 2027-12-31

Conditions

COVID-19
SARS-CoV-2 Infection

Interventions

BIOLOGICAL

No Results Yet

NCT06809764 | RECRUITING

150 participants

Clinical Effectiveness and Safety of Trastuzumab Deruxtecan (T-DXd) in Chinese Patients With HER2m NSCLC (RERUN)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-18
Start Date:: 2025-02-21
Completion:: 2027-02-12

Conditions

Non-small Cell Lung Cancer

Interventions

OTHER

No Results Yet

NCT06804928 | COMPLETED | NA

70 participants

Effect of Virtual Reality Glasses on Pain, Anxiety, and Comfort During Extracorporeal Shock Wave Lithotripsy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2025-02-01
Completion:: 2025-09-01

Conditions

ESWL
Anxiety
Pain
Comfort
Virtual Reality

Interventions

BEHAVIORAL

No Results Yet

NCT06804200 | ACTIVE_NOT_RECRUITING

800 participants

Prospective Validation of AKI Prediction

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-18
Start Date:: 2025-06-25
Completion:: 2026-08-01

Conditions

Acute Kidney Injury

No Results Yet

NCT06799065 | RECRUITING | PHASE1

90 participants

First-in-Human Study of ATX-295, an Oral Inhibitor of KIF18A, in Patients With Advanced or Metastatic Solid Tumors, Including Ovarian Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2025-03-21
Completion:: 2027-04-30

Conditions

Advanced Solid Tumors
Breast Cancer Recurrent
Ovarian Cancer
High-grade Serous Ovarian Carcinoma
Triple Negative Breast Cancer

Interventions

DRUG

No Results Yet

NCT06798142 | ACTIVE_NOT_RECRUITING

193 participants

Risk Stratification and Heterogeneity for Organ Damage in Acute Diquat Poisoning

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-18
Start Date:: 2022-02-01
Completion:: 2024-09-30

Conditions

Toxic Encephalopathy
Diquat Poisoning

Interventions

PROCEDURE

No Results Yet

NCT06795581 | RECRUITING | PHASE1

30 participants

PET Imaging of Phosphodiesterase-4B (PDE4B) in Alcohol Use Disorder

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2025-03-20
Completion:: 2028-12-11

Conditions

Alcohol Use Disorder

Interventions

DRUG

No Results Yet

NCT06792695 | RECRUITING | PHASE2

80 participants

A Study of Novel Study Interventions and Combinations in Participants With Colorectal Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2025-03-12
Completion:: 2027-06-30

Conditions

Metastatic Colorectal Cancer

Interventions

DRUG

No Results Yet

NCT06789653 | RECRUITING

80 participants

A Novel Approach Utilizing Organ Specific Age Proteomics

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-18
Start Date:: 2024-10-10
Completion:: 2027-11-01

Conditions

Breast Cancer

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06769464 | RECRUITING | NA

28 participants

Electrophysiological Representations of Odor in the Human Brain Study 1

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2024-04-01
Completion:: 2027-04-01

Conditions

Odor Intensity Ratings

Interventions

BEHAVIORAL

No Results Yet

NCT06765551 | COMPLETED

64 participants

AI Based Muscular Ultrasound to Assess Intensive Care Unit-acquired Weakness

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-18
Start Date:: 2024-10-01
Completion:: 2026-07-31

Conditions

Intensive Care Unit-acquired Weakness
Artifical Intelligence
Ultrasound

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06764316 | RECRUITING | PHASE1

148 participants

A First-in-human Study to Learn About the Safety of BAY 3547926 and How Well it Works in Participants With Advanced Liver Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2025-02-28
Completion:: 2029-07-31

Conditions

Hepatocellular Carcinoma

Interventions

DRUG

No Results Yet

NCT06756607 | RECRUITING | NA

500 participants

The ECOG-ACRIN SUPPORT Trial: Multilevel Intervention to Improve Diverse Enrollment in Cancer Clinical Trials

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2025-04-25
Completion:: 2027-08-01

Conditions

Cancer

Interventions

OTHER

No Results Yet

NCT06753097 | COMPLETED | NA

930 participants

Continuous Finger-cuff Arterial Pressure Monitoring and Intraoperative Hypotension During Non-cardiac Surgery: the Randomized DETECT II Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2025-01-06
Completion:: 2026-02-19

Conditions

Intraoperative Hypotension

Interventions

DEVICE

No Results Yet

NCT06743958 | ACTIVE_NOT_RECRUITING | NA

16 participants

Prehabilitation in Childhood Soft Tissue or Bone Sarcomas

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2025-02-20
Completion:: 2027-10-30

Conditions

Soft Tissue Sarcoma of the Lower Extremity
Bone Tumor of the Lower Extremity
Childhood and Adolescent Cancer

Interventions

OTHER

No Results Yet

NCT06743776 | NO_LONGER_AVAILABLE

Scalable Expanded Access With Analysis of Neurofilament and Other Biomarkers for Ibudilast in ALS

Study Type:: EXPANDED_ACCESS
Last Updated:: 2026-08-18

Conditions

ALS

Interventions

DRUG

No Results Yet

NCT06743126 | RECRUITING | PHASE3

360 participants

SUPRAME-ACTengine® IMA203 vs. Investigator's Choice of Treatment in Previously Treated, Unresectable or Metastatic Cutaneous Melanoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2025-01-14
Completion:: 2028-01-31

Conditions

Melanoma, Cutaneous Malignant

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT06740981 | COMPLETED

126 participants

Nutritional Intake in Patients on Noninvasive Ventilation: a Prospective Observational Study

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-18
Start Date:: 2024-12-16
Completion:: 2026-04-27

Conditions

Malnutrition or Risk of Malnutrition
Acute Respiratory Failure

Interventions

OTHER

No Results Yet

NCT06737172 | ACTIVE_NOT_RECRUITING

18 participants

Functional and Structural Outcomes Following Childhood Bone or Soft Tissue Sarcomas of the Lower Extremity

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-18
Start Date:: 2025-04-01
Completion:: 2026-10-31

Conditions

Soft Tissue Sarcoma of the Lower Extremity
Bone Sarcoma of the Lower Extremity
Childhood and Adolescent Cancer

No Results Yet

NCT06733441 | ACTIVE_NOT_RECRUITING | PHASE1

50 participants

A Study of TLN-254 in Participants With Relapsed or Refractory T-cell Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2024-12-16
Completion:: 2026-11-15

Conditions

Lymphoma

Interventions

DRUG

No Results Yet