Clinical Trials

NCT06905288 | RECRUITING

70 participants

Real-world Study on Secukinumab Effectiveness in Biologic-naïve Ankylosing Spondylitis (AS) Patients in Korea.

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-18

Start Date:

2025-04-02

Completion:

2026-12-31

Conditions

• Ankylosing Spondylitis

Interventions

• DRUG

No Results Yet

NCT06904911 | RECRUITING | PHASE2

20 participants

Intra-Arterial Tenecteplase to Improve the Microvascular Hemodynamics After Mechanical Thrombectomy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2026-02-13

Completion:

2026-12-30

Conditions

• Acute Ischemic Stroke From Large Vessel Occlusion

Interventions

• DRUG

No Results Yet

NCT06903676 | COMPLETED | NA

50 participants

Utility of Trypsinogen -2 in Early Detection and Follow Up of Post-pancreatectomy Acute Pancreatitis (PPAP)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2025-08-05

Completion:

2026-04-02

Conditions

• Pancreatitis
• Pancreatectomy

Interventions

• DEVICE

No Results Yet

NCT06888388 | RECRUITING

4700 participants

Long-term Safety of Nipple Sparing Mastectomy in Women With High Penetrance Breast Cancer Susceptibility Genes in Breast Cancer

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-18

Start Date:

2025-02-01

Completion:

2027-02-01

Conditions

• Breast Cancer Surgery

Interventions

• PROCEDURE

No Results Yet

NCT06874374 | COMPLETED | NA

40 participants

Individualized Non-invasive Brain Stimulation for the Treatment of Major Depressive Disorder

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2025-04-11

Completion:

2026-05-22

Conditions

• Depression - Major Depressive Disorder
• Transcranial Alternating Current Stimulation

Interventions

• DEVICE

No Results Yet

NCT06874205 | RECRUITING | PHASE1

40 participants

Assessment of 11C-JMJ-129 for Imaging PDE4D in Brain and Whole Body of Healthy Volunteers

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2025-04-11

Completion:

2028-02-22

Conditions

• Healthy

Interventions

• DRUG

No Results Yet

NCT06860984 | RECRUITING | PHASE3

44 participants

Evaluating the Safety and Efficacy of Duloxetine in the Prevention of Post Endoscopic Retrograde Cholangiopancreatography Pancreatitis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2025-03-10

Completion:

2027-06-20

Conditions

• Biliary Disease

Interventions

• DRUG
• OTHER

No Results Yet

NCT06857565 | COMPLETED | NA

84 participants

Study to Evaluate the Efficacy of Lactobacillus Crispatus M247 in the Prevention of Recurrent Urinary Tract Infections

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2025-03-05

Completion:

2026-04-11

Conditions

• Recurrent Urinary Tract Infection

Interventions

• DIETARY_SUPPLEMENT

No Results Yet

NCT06855732 | ACTIVE_NOT_RECRUITING | NA

204 participants

Pain Self-Management and Treatment Engagement for Patients Taking Opioids

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2024-11-25

Completion:

2026-08-31

Conditions

• Chronic Pain
• Opioid Use Disorder
• Opioid Misuse and Addiction

Interventions

• BEHAVIORAL

No Results Yet

NCT06855329 | RECRUITING

500 participants

PRospective phenotypIng and Multi-omic Endotyping of Progressive Pulmonary Fibrosis

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-18

Start Date:

2025-05-01

Completion:

2029-12-31

Conditions

• Progressive Pulmonary Fibrosis
• Interstitial Lung Disease

No Results Yet

NCT06850402 | RECRUITING | NA

400 participants

Evaluation of a Novel Optical Microscope With a Deep Depth of Field (DeepDOF) to Provide Histologic-quality Images on Cervical Biopsies and Loop Electrosurgical Excision Procedure (LEEP) Specimens at the Point-of-care

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2025-09-22

Completion:

2027-09-01

Conditions

• Cervical Cancer
• HIV

Interventions

• DEVICE

No Results Yet

NCT06846996 | RECRUITING

260 participants

Real-world Effectiveness and Safety of Trastuzumab Deruxtecan in Patients With Locally Advanced or Metastatic HER2-positive Gastric or Gastroesophageal Junction Adenocarcinoma in China

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-18

Start Date:

2025-02-27

Completion:

2027-07-31

Conditions

• HER2-positive Gastric Cancer
• HER2-positive Gastroesophageal Junction

Interventions

• DRUG

No Results Yet

NCT06841796 | ACTIVE_NOT_RECRUITING | NA

84 participants

The YMCA Healthy Lifestyle Program for Prediabetes

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2025-02-17

Completion:

2026-10-31

Conditions

• PreDiabetes

Interventions

• DEVICE

No Results Yet

NCT06835829 | ACTIVE_NOT_RECRUITING | NA

480 participants

Comparing Advanced Hemostasis and Ultrasound-Guided Puncture to Conventional Approaches in Distal Radial Access

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2025-12-31

Completion:

2026-07-30

Conditions

• Coronary Catheterization

Interventions

• DEVICE
• PROCEDURE

No Results Yet

NCT06826079 | RECRUITING | PHASE2

86 participants

Safety and Efficacy Study of Sorbitol With Neoadjuvant Chemotherapy Combined With Tirellizumab (PD-1 Inhibitor) in Patients With Locally Advanced Gastric Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2024-11-01

Completion:

2028-08-01

Conditions

• Gastric Junction Adenocarcinoma
• Gastric Cancer
• Immunotherapy
• Neoadjuvant Therapies

Interventions

• DRUG

No Results Yet

NCT06822049 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

200 participants

Remote vs. In-Person Study Evaluation (RISE) Trials: RISE Above Smoking (Trial 1)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2025-03-10

Completion:

2026-08-31

Conditions

• Remote vs. In-Person
• Remote Visits
• In-person Visits

Interventions

• DRUG

No Results Yet

NCT06810934 | RECRUITING | PHASE1/PHASE2

80 participants

A Phase 1/2A, Randomized Study of a T Follicular Helper (TFH)-Targeting Genetic Vaccine Strategy Designed to Induce Broad, Durable Immune Responses

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2025-10-21

Completion:

2027-12-31

Conditions

• COVID-19
• SARS-CoV-2 Infection

Interventions

• BIOLOGICAL

No Results Yet

NCT06809764 | RECRUITING

150 participants

Clinical Effectiveness and Safety of Trastuzumab Deruxtecan (T-DXd) in Chinese Patients With HER2m NSCLC (RERUN)

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-18

Start Date:

2025-02-21

Completion:

2027-02-12

Conditions

• Non-small Cell Lung Cancer

Interventions

• OTHER

No Results Yet

NCT06804928 | COMPLETED | NA

70 participants

Effect of Virtual Reality Glasses on Pain, Anxiety, and Comfort During Extracorporeal Shock Wave Lithotripsy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2025-02-01

Completion:

2025-09-01

Conditions

• ESWL
• Anxiety
• Pain
• Comfort
• Virtual Reality

Interventions

• BEHAVIORAL

No Results Yet

NCT06804200 | ACTIVE_NOT_RECRUITING

800 participants

Prospective Validation of AKI Prediction

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-18

Start Date:

2025-06-25

Completion:

2026-08-01

Conditions

• Acute Kidney Injury

No Results Yet

NCT06799065 | RECRUITING | PHASE1

90 participants

First-in-Human Study of ATX-295, an Oral Inhibitor of KIF18A, in Patients With Advanced or Metastatic Solid Tumors, Including Ovarian Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2025-03-21

Completion:

2027-04-30

Conditions

• Advanced Solid Tumors
• Breast Cancer Recurrent
• Ovarian Cancer
• High-grade Serous Ovarian Carcinoma
• Triple Negative Breast Cancer

Interventions

• DRUG

No Results Yet

NCT06798142 | ACTIVE_NOT_RECRUITING

193 participants

Risk Stratification and Heterogeneity for Organ Damage in Acute Diquat Poisoning

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-18

Start Date:

2022-02-01

Completion:

2024-09-30

Conditions

• Toxic Encephalopathy
• Diquat Poisoning

Interventions

• PROCEDURE

No Results Yet

NCT06795581 | RECRUITING | PHASE1

30 participants

PET Imaging of Phosphodiesterase-4B (PDE4B) in Alcohol Use Disorder

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2025-03-20

Completion:

2028-12-11

Conditions

• Alcohol Use Disorder

Interventions

• DRUG

No Results Yet

NCT06792695 | RECRUITING | PHASE2

80 participants

A Study of Novel Study Interventions and Combinations in Participants With Colorectal Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2025-03-12

Completion:

2027-06-30

Conditions

• Metastatic Colorectal Cancer

Interventions

• DRUG

No Results Yet

NCT06789653 | RECRUITING

80 participants

A Novel Approach Utilizing Organ Specific Age Proteomics

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-18

Start Date:

2024-10-10

Completion:

2027-11-01

Conditions

• Breast Cancer

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT06769464 | RECRUITING | NA

28 participants

Electrophysiological Representations of Odor in the Human Brain Study 1

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2024-04-01

Completion:

2027-04-01

Conditions

• Odor Intensity Ratings

Interventions

• BEHAVIORAL

No Results Yet

NCT06765551 | COMPLETED

64 participants

AI Based Muscular Ultrasound to Assess Intensive Care Unit-acquired Weakness

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-18

Start Date:

2024-10-01

Completion:

2026-07-31

Conditions

• Intensive Care Unit-acquired Weakness
• Artifical Intelligence
• Ultrasound

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT06764316 | RECRUITING | PHASE1

148 participants

A First-in-human Study to Learn About the Safety of BAY 3547926 and How Well it Works in Participants With Advanced Liver Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2025-02-28

Completion:

2029-07-31

Conditions

• Hepatocellular Carcinoma

Interventions

• DRUG

No Results Yet

NCT06756607 | RECRUITING | NA

500 participants

The ECOG-ACRIN SUPPORT Trial: Multilevel Intervention to Improve Diverse Enrollment in Cancer Clinical Trials

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2025-04-25

Completion:

2027-08-01

Conditions

• Cancer

Interventions

• OTHER

No Results Yet

NCT06753097 | COMPLETED | NA

930 participants

Continuous Finger-cuff Arterial Pressure Monitoring and Intraoperative Hypotension During Non-cardiac Surgery: the Randomized DETECT II Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2025-01-06

Completion:

2026-02-19

Conditions

• Intraoperative Hypotension

Interventions

• DEVICE

No Results Yet

NCT06743958 | ACTIVE_NOT_RECRUITING | NA

16 participants

Prehabilitation in Childhood Soft Tissue or Bone Sarcomas

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2025-02-20

Completion:

2027-10-30

Conditions

• Soft Tissue Sarcoma of the Lower Extremity
• Bone Tumor of the Lower Extremity
• Childhood and Adolescent Cancer

Interventions

• OTHER

No Results Yet

NCT06743776 | NO_LONGER_AVAILABLE

Scalable Expanded Access With Analysis of Neurofilament and Other Biomarkers for Ibudilast in ALS

Study Type:

EXPANDED_ACCESS

Last Updated:

2026-08-18

Conditions

• ALS

Interventions

• DRUG

No Results Yet

NCT06743126 | RECRUITING | PHASE3

360 participants

SUPRAME-ACTengine® IMA203 vs. Investigator's Choice of Treatment in Previously Treated, Unresectable or Metastatic Cutaneous Melanoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2025-01-14

Completion:

2028-01-31

Conditions

• Melanoma, Cutaneous Malignant

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT06740981 | COMPLETED

126 participants

Nutritional Intake in Patients on Noninvasive Ventilation: a Prospective Observational Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-18

Start Date:

2024-12-16

Completion:

2026-04-27

Conditions

• Malnutrition or Risk of Malnutrition
• Acute Respiratory Failure

Interventions

• OTHER

No Results Yet

NCT06737172 | ACTIVE_NOT_RECRUITING

18 participants

Functional and Structural Outcomes Following Childhood Bone or Soft Tissue Sarcomas of the Lower Extremity

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-18

Start Date:

2025-04-01

Completion:

2026-10-31

Conditions

• Soft Tissue Sarcoma of the Lower Extremity
• Bone Sarcoma of the Lower Extremity
• Childhood and Adolescent Cancer

No Results Yet

NCT06733441 | ACTIVE_NOT_RECRUITING | PHASE1

50 participants

A Study of TLN-254 in Participants With Relapsed or Refractory T-cell Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2024-12-16

Completion:

2026-11-15

Conditions

• Lymphoma

Interventions

• DRUG

No Results Yet

NCT06731907 | RECRUITING | PHASE2

90 participants

A Study of Pembrolizumab With or Without Chemotherapy in Combination With Additional Treatments for Advanced Non-Small Cell Lung Cancer (NSCLC) (MK-3475-01G/KEYMAKER U01)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2025-03-30

Completion:

2032-03-12

Conditions

• Non-small Cell Lung Cancer

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT06728072 | RECRUITING | PHASE2

97 participants

Addition of Antibiotics to Upfront Treatment Regimen for Colorectal Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2025-03-07

Completion:

2035-07-01

Conditions

• Colorectal Cancer
• CRC

Interventions

• DRUG

No Results Yet

NCT06720090 | RECRUITING | EARLY_PHASE1

40 participants

Light Therapy for Obsessive-compulsive Disorder (OCD)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-18

Start Date:

2024-12-16

Completion:

2029-03-31

Conditions

• OCD

Interventions

• BEHAVIORAL

No Results Yet

NCT06717178 | COMPLETED

360 participants

Cancer and Aging Research Group (CARG) Chemotherapy Toxicity Risk Scores in Older Adults With Cancer in China

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-18

Start Date:

2024-12-24

Completion:

2025-12-31

Conditions

• Cancer
• Cancer-related Problem/Condition

Interventions

• DRUG

No Results Yet