Clinical Trials Updated in 2026

NCT05670496 | RECRUITING

600 participants

Collection of Clinical Data and Specimens for Research in Hearing, Balance, Taste, Smell, Voice, Speech, and Language Disorders.

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-18
Start Date:: 2023-03-08
Completion:: 2027-08-01

Conditions

Hearing Loss
Deafness

No Results Yet

NCT05657405 | RECRUITING

1250 participants

Observational Study of Advanced Data Analytics in Genetic Conditions

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-18
Start Date:: 2026-07-29
Completion:: 2032-12-31

Conditions

Genetic Conditions

No Results Yet

NCT05657106 | ACTIVE_NOT_RECRUITING | NA

752 participants

Kentucky Outreach Service Kiosk (KyOSK): Reducing HIV, HCV, and Overdose Risk

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2023-03-06
Completion:: 2027-05-31

Conditions

Opioid-Related Disorders
Hepatitis C (HCV)
Human Immunodeficiency Virus (HIV)
Drug Overdose
Substance Abuse
Intravenous Drug Usage
Opiate Substitution Treatment
Sexually Transmitted Diseases

Interventions

BEHAVIORAL

No Results Yet

NCT05653193 | ACTIVE_NOT_RECRUITING | PHASE2

50 participants

Interferon-gamma as Adjunctive Therapy in Chronic Pulmonary Aspergillosis: a Randomised Feasibility Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2024-05-17
Completion:: 2026-11-30

Conditions

Chronic Pulmonary Aspergillosis
Aspergillosis

Interventions

DRUG

No Results Yet

NCT05651932 | RECRUITING | PHASE1

165 participants

A Study of an MMSET Inhibitor in Patients With Relapsed and Refractory Multiple Myeloma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2023-02-22
Completion:: 2027-12-31

Conditions

Multiple Myeloma
Myeloma
Myeloma Multiple

Interventions

DRUG

No Results Yet

NCT05645328 | ACTIVE_NOT_RECRUITING | NA

31 participants

Implementation of a Health System Intervention to Improve Quality of Cancer Care for Rural Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2023-01-20
Completion:: 2026-12-31

Conditions

Cancer

Interventions

OTHER

No Results Yet

NCT05621668 | ACTIVE_NOT_RECRUITING | PHASE1

5 participants

A First-In-Human Phase 1 Trial of T-Cell Membrane-Anchored Tumor Targeted Il12 (Attil12)- T-Cell Therapy in Subjects With Advanced/Metastatic Soft Tissue and Bone Sarcoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2023-09-08
Completion:: 2027-09-30

Conditions

Soft Tissue Sarcoma
Bone Sarcoma

Interventions

DRUG

No Results Yet

NCT05604534 | RECRUITING

200 participants

Assessing and Improving Quantitative Magnetic Resonance Imaging Metrics in Human Subjects

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-18
Start Date:: 2023-02-02
Completion:: 2041-03-31

Conditions

Normal Physiology

No Results Yet

NCT05587023 | COMPLETED | NA

62 participants

Effect of Ultrasound-guided Left Stellate Ganglion Block on Rapid Recovery of Patients Undergoing Cardiac Valve Replacement and Its Mechanism

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2022-10-16
Completion:: 2023-12-30

Conditions

Stellate Ganglion Block
Heart Valve Replacement (Mechanical or Biological With AF)

Interventions

PROCEDURE

No Results Yet

NCT05586581 | RECRUITING | PHASE1/PHASE2

70 participants

SV2A & TSPO PET Imaging Measures to Reveal Mechanisms of HIV Neuropathogenesis During Antiretroviral Therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2023-05-17
Completion:: 2028-12-31

Conditions

HIV Associated Neurocognitive Disorder
HIV Dementia
HIV Encephalitis
Healthy

Interventions

DRUG

No Results Yet

NCT05558514 | COMPLETED | NA

24 participants

Place-based Cochlear Implant Mapping

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2023-06-07
Completion:: 2026-06-24

Conditions

Hearing Loss, Sensorineural
Cochlear Implants

Interventions

OTHER

No Results Yet

NCT05541276 | RECRUITING | PHASE3

676 participants

MELAtonin for Prevention of Postoperative Agitation and Emergence Delirium in Children

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2025-01-21
Completion:: 2027-03-01

Conditions

Emergence Delirium

Interventions

DRUG

No Results Yet

NCT05521854 | COMPLETED | NA

62 participants

Contingency Management for Drug Use: Does Age Matter?

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2023-05-01
Completion:: 2026-05-26

Conditions

Opioid Use Disorder
Methamphetamine Abuse
Cocaine Use Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT05471128 | ACTIVE_NOT_RECRUITING

29 participants

MRI Fusion Biopsy vs. Micro-Ultrasound Guided Biopsy

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-18
Start Date:: 2023-01-27
Completion:: 2025-05-01

Conditions

Prostate Cancer

Interventions

PROCEDURE

No Results Yet

NCT05470504 | RECRUITING | PHASE2

25 participants

Study of Growth Hormone Inhibition Using Pegvisomant in Severe Insulin Resistance

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2023-01-23
Completion:: 2028-01-30

Conditions

Insulin Receptor Mutation
Partial Lipodystrophy

Interventions

DRUG

No Results Yet

NCT05435014 | TERMINATED | PHASE1/PHASE2

2 participants

T-ACE Oil by TAE/TACE in Patients With Hepatocellular Carcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2022-09-13
Completion:: 2026-06-15

Conditions

Hepatocellular Carcinoma

Interventions

DRUG

No Results Yet

NCT05431088 | RECRUITING | PHASE2/PHASE3

389 participants

A Phase 2/3 Study of Osivelotor in Adult and Adolescent Participants With SCD

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2022-09-22
Completion:: 2030-12-30

Conditions

Sickle Cell Disease

Interventions

DRUG

No Results Yet

NCT05426057 | RECRUITING | NA

468 participants

Mental Health in Primary Care

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2022-04-26
Completion:: 2028-04-30

Conditions

Depression, Anxiety
Suicide
Drug Use

Interventions

BEHAVIORAL

No Results Yet

NCT05421741 | RECRUITING | PHASE4

242 participants

Prophylactic Antibiotic Coated Nail to Prevent Infection: A Clinical Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2023-05-15
Completion:: 2026-12-31

Conditions

Osteomyelitis Tibia
Tibial Fractures
Open Tibia Fracture

Interventions

DRUG
OTHER

No Results Yet

NCT05419037 | RECRUITING

90 participants

Natural History of Pregnancy and Pregnancy Outcomes in Metreleptin-Treated vs Untreated Subjects With Lipodystrophy

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-18
Start Date:: 2022-09-07
Completion:: 2028-03-01

Conditions

Lipodystrophy

No Results Yet

NCT05410977 | RECRUITING

950 participants

Collecting Blood and Stool Samples to Detect Colorectal Cancer or Advanced Neoplasia in Lynch Syndrome Patients

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-18
Start Date:: 2022-03-30
Completion:: 2027-12-31

Conditions

Colorectal Carcinoma
Lynch Syndrome

Interventions

PROCEDURE
OTHER

No Results Yet

NCT05393154 | COMPLETED

55 participants

Pilot Study of Biopsy Scanner for Evaluation of Bronchoscopic Small Biopsy Specimens to Determine Adequacy

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-18
Start Date:: 2021-09-22
Completion:: 2022-10-26

Conditions

Lung Cancer

Interventions

DEVICE

No Results Yet

NCT05307679 | TERMINATED | PHASE2

7 participants

A Study to Evaluate the Safety and Efficacy of Basmisanil Treatment in Children Aged 2-14 Years With Dup15q Syndrome

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2022-12-16
Completion:: 2024-03-04

Conditions

Dup15q Syndrome

Interventions

DRUG

Results Available

NCT05277688 | RECRUITING | PHASE3

340 participants

Adjuvant Concurrent Chemoradiotherapy Versus Radiotherapy in Early-stage Cervical Cancer Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2022-03-15
Completion:: 2027-12-30

Conditions

Cervical Cancer

Interventions

DRUG
RADIATION

No Results Yet

NCT05277116 | ACTIVE_NOT_RECRUITING | NA

26877 participants

The Electronic Medical Records and GEnomics (eMERGE) Network Genomic Risk Assessment

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2022-02-16
Completion:: 2030-04-30

Conditions

Genetic Disease

Interventions

OTHER

No Results Yet

NCT05273567 | COMPLETED | PHASE2

22 participants

A Trial of Guanfacine-er for Cannabis Use Disorder

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2022-06-01
Completion:: 2023-09-08

Conditions

Cannabis Use

Interventions

DRUG
OTHER

Results Available

NCT05267951 | RECRUITING | NA

9 participants

Closed-loop Spinal Stimulation for Restoration of Upper Extremity Function After Spinal Cord Injury

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2022-10-12
Completion:: 2027-12-31

Conditions

Spinal Cord Injuries

Interventions

DEVICE
OTHER

No Results Yet

NCT05246514 | ACTIVE_NOT_RECRUITING | PHASE2

72 participants

A Single Arm Phase 2 Study to Evaluate Efficacy and Safety of Trastuzumab Deruxtecan for Patients With HER2 Mutant NSCLC

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2022-07-13
Completion:: 2024-11-04

Conditions

HER2-mutant Non-Small Cell Lung Cancer

Interventions

DRUG

Results Available

NCT05227105 | ACTIVE_NOT_RECRUITING | NA

640 participants

PA Moves Trial - Patient Participants

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2023-05-23
Completion:: 2027-08-31

Conditions

Overweight or Obesity
Diabetes Mellitus, Type 2
Physical Inactivity

Interventions

BEHAVIORAL

No Results Yet

NCT05215353 | RECRUITING | PHASE4

368 participants

A Study Comparing Music Therapy and Cognitive Behavioral Therapy for Anxiety in Cancer Survivors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2022-01-14
Completion:: 2027-01-31

Conditions

Survivorship

Interventions

OTHER

No Results Yet

NCT05213676 | RECRUITING | PHASE4

600 participants

De-implementing Inhaled Nitric Oxide for Congenital Diaphragmatic Hernia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2025-11-01
Completion:: 2030-10-31

Conditions

Congenital Diaphragmatic Hernia

Interventions

DRUG
OTHER

No Results Yet

NCT05177510 | RECRUITING | PHASE2

400 participants

Mifepristone Outpatient Labour Induction

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2023-08-25
Completion:: 2027-03-31

Conditions

Labor, Induced

Interventions

DRUG

No Results Yet

NCT05165940 | NOT_YET_RECRUITING | NA

40 participants

Facilitating Transition to Recommended PTSD Treatment

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2026-12-01
Completion:: 2027-05-03

Conditions

PTSD

Interventions

BEHAVIORAL

No Results Yet

NCT05162846 | COMPLETED | NA

793 participants

Michigan Genetic Hereditary Testing (MiGHT)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2022-04-21
Completion:: 2025-07-13

Conditions

Breast Cancer
Colorectal Cancer
Ovarian Cancer
Prostate Cancer
Pancreatic Cancer
Endometrial Cancer
History of Cancer

Interventions

OTHER
BEHAVIORAL

Results Available

NCT05156281 | ACTIVE_NOT_RECRUITING | PHASE3

1007 participants

Efficacy and Safety of Remibrutinib Compared to Teriflunomide in Participants With Relapsing Multiple Sclerosis (RMS) (REMODEL-2)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2021-12-13
Completion:: 2026-07-22

Conditions

Relapsing Multiple Sclerosis

Interventions

DRUG

No Results Yet

NCT05147220 | ACTIVE_NOT_RECRUITING | PHASE3

1000 participants

Efficacy and Safety of Remibrutinib Compared to Teriflunomide in Participants With Relapsing Multiple Sclerosis (RMS) (REMODEL-1)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2021-12-16
Completion:: 2026-07-21

Conditions

Relapsing Multiple Sclerosis

Interventions

DRUG

No Results Yet

NCT05143177 | TERMINATED | PHASE2/PHASE3

486 participants

A Study to Evaluate the Efficacy and Safety of DA-1229 (Evogliptin) in Patient's Calcific Aortic Valve Disease With Mild to Moderate Aortic Stenosis (EVOID-AS)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2022-06-27
Completion:: 2026-03-21

Conditions

Calcific Aortic Valve Disease

Interventions

DRUG

No Results Yet

NCT05132426 | WITHDRAWN | NA

0 participants

Osteopathic Manipulative Treatment for Recurrent Mastitis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2021-10-29
Completion:: 2022-12-31

Conditions

Mastitis

Interventions

PROCEDURE

No Results Yet

NCT05095519 | COMPLETED | PHASE2

30 participants

Hepatocellular Carcinoma Imaging Using PSMA PET/CT

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2021-09-08
Completion:: 2026-05-08

Conditions

Hepatocellular Carcinoma

Interventions

DRUG

No Results Yet

NCT05092542 | ACTIVE_NOT_RECRUITING | NA

1212 participants

Intervention to Address Disparate Mental Health Consequences of COVID-19 Pandemic on Latinx and African Newcomers

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-18
Start Date:: 2021-10-18
Completion:: 2025-07-31

Conditions

Mental Health Issue
Mental Health Disorder
Stress, Emotional
Economic Problems

Interventions

BEHAVIORAL

No Results Yet