A Phase 2/3 Study in Adult and Adolescent Participants With SCD

A Study of the Effect of IW-1701 (Olinciguat), a Stimulator of Soluble Guanylate Cyclase (sGC), on Patients With Sickle Cell Disease (SCD)

NCT03285178 ·Status: COMPLETED ·Phase: PHASE2

A Study to Evaluate GBT021601-012 Single Dose and Multiple Dose in Participants With Sickle Cell Disease (SCD)

NCT04983264 ·Status: COMPLETED ·Phase: PHASE1

Voxelotor Neurocognitive Function Study

NCT05228834 ·Status: TERMINATED ·Phase: PHASE3

A Study to Evaluate the Long-term Safety of Inclacumab Administered to Participants With Sickle Cell Disease

NCT05348915 ·Status: TERMINATED ·Phase: PHASE3

Hemolysis Related Complications in SCD. A Phase II Study With Voxelotor

NCT05199766 ·Status: UNKNOWN ·Phase: PHASE2

Expanded Access to Voxelotor for Patients With Sickle Cell Disease Who Have No Alternative Treatment Options

NCT03943615 ·Status: NO_LONGER_AVAILABLE

Study of SANGUINATE™ In the Treatment of Sickle Cell Disease Patients With Vaso-Occlusive Crisis

NCT02411708 ·Status: COMPLETED ·Phase: PHASE2

Assessment of Tolerance of Mobilizing Peripheral Hematopoietic Stem Cells by Plerixafor in Sickle Cell Patients

NCT02212535 ·Status: COMPLETED ·Phase: PHASE1/PHASE2

Dose Escalation Study of PF-07209326 in Healthy Participants and Participants With Sickle Cell Disease

NCT04255875 ·Status: COMPLETED ·Phase: PHASE1

Voxelotor Sickle Cell Exercise Study

NCT04581356 ·Status: COMPLETED ·Phase: PHASE4

Evaluation of Different Dose Regimens of Aes-103 Given for 28 Days to Subjects With Stable Sickle Cell Disease

NCT01987908 ·Status: TERMINATED ·Phase: PHASE2

Efficacy and Safety of Tocilizumab for Acute Chest Syndrome Treatment in Patients With Sickle Cell Disease

NCT06818266 ·Status: NOT_YET_RECRUITING ·Phase: PHASE3

A Study to Evaluate Safety, Pharmacokinetic, and Biological Activity of INCB059872 in Subjects With Sickle Cell Disease

NCT03132324 ·Status: TERMINATED ·Phase: PHASE1

Safety of Blood Stem Cell Mobilization With Plerixafor in Patients With Sickle Cell Disease

NCT03664830 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1

A Relative Bioavailability Study of a Prasugrel Orally Disintegrating Tablet

NCT01430091 ·Status: COMPLETED ·Phase: PHASE1

Trial of Zileuton CR in Children and Adults With Sickle Cell Disease

NCT01136941 ·Status: COMPLETED ·Phase: PHASE1

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Long-term Mitapivat Dosing in Subjects With Stable Sickle Cell Disease: An Extension of a Phase I Pilot Study of Mitapivat

NCT04610866 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1/PHASE2

Safety of Rivipansel (GMI-1070) in the Treatment of One or More Vaso-Occlusive Crises in Hospitalized Subjects With Sickle Cell Disease

NCT02433158 ·Status: TERMINATED ·Phase: PHASE3

Losartan for Diffuse Myocardial Fibrosis in Sickle Cell Disease

NCT05012631 ·Status: RECRUITING ·Phase: PHASE2

A GBT021601 ADME Microtracer Study in Healthy Volunteers

NCT05718687 ·Status: COMPLETED ·Phase: PHASE1

The Effect of Voxelotor on Cerebral Hemodynamic Response in Children With Sickle Cell Anemia

NCT05018728 ·Status: TERMINATED ·Phase: PHASE2

Assessing Physical Function in Sickle Cell Patients Taking Voxelotor

NCT06023199 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2

A Study to Evaluate GBT021601 in Single and Multiple Doses in Healthy Participants

NCT05036512 ·Status: COMPLETED ·Phase: PHASE1

Voxelotor Brain Oxygenation and Neurocognitive Study

NCT05228821 ·Status: WITHDRAWN ·Phase: PHASE4

Open-Label Study of Oral CEP-701 (Lestaurtinib) in Patients With Polycythemia Vera or Essential Thrombocytosis

NCT00586651 ·Status: COMPLETED ·Phase: PHASE2