Clinical Trials Updated in 2026

NCT07221357 | RECRUITING | PHASE2/PHASE3

990 participants

A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Bevacizumab in Combination With Chemotherapy in Participants With Previously Untreated, Unresectable, or Metastatic Colorectal Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-12-31
Completion:: 2030-02-02

Conditions

Untreated, Unresectable, or Metastatic Colorectal Cancer

Interventions

DRUG

No Results Yet

NCT07218770 | TERMINATED | PHASE1/PHASE2

1 participants

A Study of REGN7041 for Active Noninfectious Uveitis in Adult Participants

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-12-17
Completion:: 2026-07-21

Conditions

Active Noninfectious Uveitis Affecting the Posterior Segment

Interventions

DRUG

No Results Yet

NCT07217613 | COMPLETED | NA

100 participants

Prospective Evaluation of Silk Fibroin Incision Dressings in ACL Reconstruction

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-10-14
Completion:: 2026-05-01

Conditions

Anterior Cruciate Ligament Reconstruction

Interventions

DEVICE

No Results Yet

NCT07211308 | RECRUITING

200 participants

Open and Closed Loop DTM SCS in Patients With PSPS Type 2: ENDLESS Study

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-12-12
Completion:: 2028-01-01

Conditions

Persistent Spinal Pain Syndrome Type 2
Failed Back Surgery Syndrome
Failed Neck Surgery Syndrome

Interventions

DEVICE

No Results Yet

NCT07209813 | RECRUITING | PHASE2

48 participants

GKL-006 Injection Plus TACE Versus TACE Alone in Patients With Unresectable Hepatocellular Carcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-11-14
Completion:: 2027-09-30

Conditions

Hepatocellular Carcinoma (HCC)
Unresectable Hepatocellular Cancer

Interventions

DRUG
PROCEDURE

No Results Yet

NCT07209371 | RECRUITING | PHASE2

50 participants

Rifaximin Versus No Intervention for the Treatment of IgG/IgA (Non-IgM) Monoclonal Gammopathy of Undetermined Significance

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-01-22
Completion:: 2028-05-01

Conditions

IgA Monoclonal Gammopathy of Undetermined Significance
Non-IgM Monoclonal Gammopathy of Undetermined Significance

Interventions

DRUG
PROCEDURE

No Results Yet

NCT07209267 | NOT_YET_RECRUITING | PHASE2

35 participants

Baricitinib Curative Repression of HIV-1

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-10-31
Completion:: 2028-01-31

Conditions

HIV Infection
HIV

Interventions

DRUG

No Results Yet

NCT07209228 | RECRUITING | NA

60 participants

Haptics in Virtual Reality

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-12-01
Completion:: 2028-12-23

Conditions

Literacy
Literacy-language Intervention
Haptics

Interventions

BEHAVIORAL

No Results Yet

NCT07206628 | RECRUITING

200 participants

Real-world Study to Assess Adherence to IOP Lowering Therapy in Patients With Glaucoma or Ocular Hypertension Using CONNECTDROP®

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-09-19
Completion:: 2027-09-30

Conditions

Adherence to Glaucoma Therapy

No Results Yet

NCT07205068 | RECRUITING | NA

100 participants

Improved Outcomes With Pre-Procedure Shockwave IVL of Common Femoral Artery Access Site Prior to Large Bore Access and Pre-Closure

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-10-04
Completion:: 2028-10-04

Conditions

Aortic Stenosis

Interventions

DEVICE
PROCEDURE

No Results Yet

NCT07202247 | RECRUITING | PHASE2

60 participants

Metabolic Interventions (Time-Restricted Eating, GLP1 Receptor Agonist, and Heart Healthy Diet) to Improve Cardiometabolic Health in Prostate Cancer Patients During Androgen Deprivation Therapy, IMPACT-ADT Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-11-05
Completion:: 2028-04-09

Conditions

Prostate Carcinoma
Recurrent Prostate Carcinoma

Interventions

DRUG
BEHAVIORAL
PROCEDURE
OTHER
RADIATION

No Results Yet

NCT07185451 | RECRUITING | NA

30 participants

Efficacy and Safety of Transcranial Alternating Current Stimulation (tACS) Combined With Stable Medication in Adolescents With Depression

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-10-01
Completion:: 2027-03-30

Conditions

Depression - Major Depressive Disorder

Interventions

DEVICE

No Results Yet

NCT07180355 | RECRUITING | PHASE1

10 participants

A Study of SGT-212 Gene Therapy in Friedreich's Ataxia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-10-22
Completion:: 2028-03-21

Conditions

Friedreich's Ataxia (FA)

Interventions

DRUG

No Results Yet

NCT07176689 | RECRUITING | PHASE4

50 participants

Nirogacestat in Premenopausal Females With Desmoid Tumor/Aggressive Fibromatosis (DT/AF)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-09-17
Completion:: 2031-02-26

Conditions

Desmoid Tumor
Aggressive Fibromatosis

Interventions

DRUG

No Results Yet

NCT07173101 | TERMINATED | PHASE2

7 participants

Clinical Investigation of the Effects of Semiconductor Embedded Therapeutic Garments on Cancer-related Cognitive Impairment in Breast and Gynecological Cancer Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-11-07
Completion:: 2026-07-03

Conditions

Breast Cancer
Gynecologic Cancer
Cancer-related Cognitive Difficulties

Interventions

DEVICE

No Results Yet

NCT07170553 | RECRUITING | NA

30 participants

Relationship Enhancement Digital Game

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-05-15
Completion:: 2027-04-30

Conditions

Parent-Child Relations
Parenting
Attachment Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT07166406 | RECRUITING | PHASE3

226 participants

Testing Immunotherapy With or Without Stereotactic Body Radiation Therapy in Patients With Advanced Liver Cancer, HELIO-RT Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-02-26
Completion:: 2029-03-10

Conditions

Advanced Hepatocellular Carcinoma
Stage III Hepatocellular Carcinoma AJCC v8
Stage IV Hepatocellular Carcinoma AJCC v8

Interventions

BIOLOGICAL
PROCEDURE
OTHER
RADIATION

No Results Yet

NCT07166133 | RECRUITING | NA

125 participants

GORE® TAG® Thoracic Branch Endoprosthesis Zone 0/1 Post-Approval Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-03-02
Completion:: 2028-07-31

Conditions

Aortic Arch Dissection
Aortic Arch Aneurysm

Interventions

DEVICE

No Results Yet

NCT07161700 | ENROLLING_BY_INVITATION | PHASE2

360 participants

An Open-Label Extension Study to Evaluate the Safety and Tolerability of SPT-300 (GlyphAllo) in Participants With Major Depressive Disorder, With or Without Anxious Distress (BUOY-1 OLE Study)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-09-02
Completion:: 2027-05-31

Conditions

Major Depressive Disorder (MDD)
Major Depressive Disorder With Anxious Distress

Interventions

DRUG

No Results Yet

NCT07157033 | RECRUITING | PHASE1/PHASE2

36 participants

A Phase 1 Study to Evaluate Safety and Efficacy of XER-001 (Amifostine for Nasoduodenal Delivery) in Combination With Sterotactic Body Radiotherapy for Treatment in Patients With Locally Advanced Pancreatic Cancer.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-01-01
Completion:: 2029-07-31

Conditions

Locally Advanced Pancreatic Adenocarcinoma
Locally Advanced Pancreas Cancer
Locally Advanced Pancreatic Ductal Adenocarcinoma

Interventions

DRUG

No Results Yet

NCT07149870 | RECRUITING | NA

432 participants

Pain Management Teams Using Whole Health to Optimize Function and Safety in Veterans: The TEAMWORK Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-11-20
Completion:: 2029-10-01

Conditions

Chronic Pain

Interventions

OTHER

No Results Yet

NCT07149272 | COMPLETED | NA

153 participants

Lactate Kinetics After Multimodal Exercise and Adjunctive Virtual Reality Exercise in Hospitalized Geriatric Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2024-02-16
Completion:: 2025-05-30

Conditions

Fatigue
Lactate
Frailty
Sarcopenia in Elderly
Quality of Life

Interventions

DEVICE

No Results Yet

NCT07148713 | ACTIVE_NOT_RECRUITING | NA

60 participants

Pilot of Continuous Glucose Monitor-Augmented Food Is Medicine

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-09-19
Completion:: 2026-12-31

Conditions

Nutrition
Type 2 Diabetes
T2DM
T2DM (Type 2 Diabetes Mellitus)
Diabetes Education
Diabetes Type 2
Diabetes Mellitis

Interventions

BEHAVIORAL

No Results Yet

NCT07146022 | ACTIVE_NOT_RECRUITING | PHASE3

552 participants

Safety and Efficacy of VDPHL01 in Females With Androgenetic Alopecia (AGA)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-07-25
Completion:: 2027-06-30

Conditions

Androgenetic Alopecia (AGA)
Androgenetic Alopecia
AGA
Female Androgenetic Alopecia
Hair Loss

Interventions

DRUG

No Results Yet

NCT07144826 | RECRUITING | EARLY_PHASE1

161 participants

Effects of a Probiotic Intervention on the Gut and Vaginal Microbiome in Patients With Advanced or Recurrent Ovarian Cancer Undergoing Treatment With Platinum Chemotherapy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-03-06
Completion:: 2027-07-09

Conditions

Advanced Ovarian Carcinoma
Recurrent Ovarian Carcinoma
Stage II Ovarian Cancer AJCC v8
Stage III Ovarian Cancer AJCC v8
Stage IV Ovarian Cancer AJCC v8

Interventions

PROCEDURE
DRUG
DIETARY_SUPPLEMENT
OTHER

No Results Yet

NCT07140016 | RECRUITING | PHASE1

40 participants

A Study of Gilteritinib in Adults With Advanced ALK-positive Non-small Cell Lung Cancer (NSCLC)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-09-22
Completion:: 2029-12-31

Conditions

Non-small Cell Lung Cancer (NSCLC)
Anaplastic Lymphoma Kinase (ALK) Positive

Interventions

DRUG

No Results Yet

NCT07139990 | RECRUITING | PHASE1

105 participants

Personalized Radiotherapy for Individualized Treatment Strategies and Monitoring (PRISM)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-10-28
Completion:: 2030-09-01

Conditions

Small Cell Lung Cancer Extensive Stage
Brain Metastases
Solid Tumor, Adult
Thoracic Cancer
Sarcoma,Soft Tissue
HNPCC

Interventions

RADIATION

No Results Yet

NCT07137624 | RECRUITING | NA

20 participants

Motor Imagery and Action Observation for Gait Function in MS

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-01-03
Completion:: 2026-08-31

Conditions

Multiple Sclerosis

Interventions

BEHAVIORAL

No Results Yet

NCT07134179 | COMPLETED

25 participants

Insufficient Regional Anesthesia for Cesarean Section: Mothers' Experiences A Qualitative Study

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-08-15
Completion:: 2026-04-01

Conditions

Caesarean Section
Regional Anesthesia

Interventions

OTHER

No Results Yet

NCT07133880 | RECRUITING | PHASE4

72 participants

Compare the Effects of Nebulizer Versus Inhaler Based Therapy for COPD Using Long-acting Bronchodilators

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2023-12-05
Completion:: 2026-12-01

Conditions

COPD (Chronic Obstructive Pulmonary Disease)

Interventions

DRUG

No Results Yet

NCT07131371 | ACTIVE_NOT_RECRUITING

2500 participants

Stratification, Management, and Guidance of Hypertrophic Cardiomyopathy Patients Using Hybrid Digital Twin Solutions

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-17
Start Date:: 2024-01-15
Completion:: 2026-12-31

Conditions

HCM - Hypertrophic Cardiomyopathy

No Results Yet

NCT07123779 | RECRUITING | PHASE1/PHASE2

126 participants

HS235 Study in Obese Participants With Pulmonary Hypertension and Heart Failure With Preserved Ejection Fraction (HFpEF)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-08-31
Completion:: 2029-01-31

Conditions

Pulmonary Hypertension
Heart Failure With Preserved Ejection Fraction

Interventions

BIOLOGICAL
OTHER

No Results Yet

NCT07121894 | RECRUITING | NA

30 participants

Ketogenic Intervention for Bipolar Depression

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-08-12
Completion:: 2028-12-31

Conditions

Bipolar Depression

Interventions

BEHAVIORAL

No Results Yet

NCT07116941 | COMPLETED | NA

124 participants

Multisensory and Cognitive Interventions in the ICU: Effects on Health and Recovery

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-08-01
Completion:: 2026-08-13

Conditions

Coronary Artery Bypass Graft (CABG)
Cardiac Surgery Subjects
Postoperative Care

Interventions

BEHAVIORAL

No Results Yet

NCT07112404 | RECRUITING | NA

42 participants

Pain Intervention With Needling: Pilot Of Integrated Neuromodulation Techniques

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-10-23
Completion:: 2027-08-31

Conditions

Pain
Back Pain
Lower Back Pain
Quality of Life

Interventions

OTHER

No Results Yet

NCT07106970 | RECRUITING | NA

640 participants

PVI Alone vs PVI and Linear Ablation for Persistent Atrial Fibrillation (PROMPT AF II)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-08-28
Completion:: 2027-12-30

Conditions

Persistent Atrial Fibrillation

Interventions

PROCEDURE

No Results Yet

NCT07105059 | RECRUITING | PHASE1

18 participants

A Study of Teclistamab and Mezigdomide in People With Multiple Myeloma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-08-08
Completion:: 2028-08-08

Conditions

Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT07102212 | SUSPENDED | NA

120 participants

Telemedicine-mHealth Symptom Cluster Intervention for Advanced Cancer Patients: Finding Our Center Under Stress (FOCUS)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-11-15
Completion:: 2028-08-31

Conditions

Lung Cancer
Breast Cancer
Prostate Cancer
Multiple Myeloma
Melanoma

Interventions

BEHAVIORAL

No Results Yet

NCT07092020 | COMPLETED | NA

220 participants

Extended Depth of Focus (EDF) Intraocular Lens (IOL) Versus Monofocal Intracoular Lens (IOL)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-10-01
Completion:: 2026-07-27

Conditions

Cataract Senile

Interventions

DEVICE

No Results Yet

NCT07091864 | RECRUITING | NA

116 participants

Continuous Glucose Monitoring for the Management of Hyperglycemia in Patients With Glioblastoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-07-29
Completion:: 2027-11-30

Conditions

Glioblastoma, IDH-Wildtype
WHO Grade 4 Glioma

Interventions

OTHER
PROCEDURE

No Results Yet