Clinical Trials Updated in 2026

NCT07211308 | RECRUITING

200 participants

Open and Closed Loop DTM SCS in Patients With PSPS Type 2: ENDLESS Study

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-12-12
Completion:: 2028-01-01

Conditions

Persistent Spinal Pain Syndrome Type 2
Failed Back Surgery Syndrome
Failed Neck Surgery Syndrome

Interventions

DEVICE

No Results Yet

NCT07209813 | RECRUITING | PHASE2

48 participants

GKL-006 Injection Plus TACE Versus TACE Alone in Patients With Unresectable Hepatocellular Carcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-11-14
Completion:: 2027-09-30

Conditions

Hepatocellular Carcinoma (HCC)
Unresectable Hepatocellular Cancer

Interventions

DRUG
PROCEDURE

No Results Yet

NCT07209371 | RECRUITING | PHASE2

50 participants

Rifaximin Versus No Intervention for the Treatment of IgG/IgA (Non-IgM) Monoclonal Gammopathy of Undetermined Significance

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-01-22
Completion:: 2028-05-01

Conditions

IgA Monoclonal Gammopathy of Undetermined Significance
Non-IgM Monoclonal Gammopathy of Undetermined Significance

Interventions

DRUG
PROCEDURE

No Results Yet

NCT07209267 | NOT_YET_RECRUITING | PHASE2

35 participants

Baricitinib Curative Repression of HIV-1

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-10-31
Completion:: 2028-01-31

Conditions

HIV Infection
HIV

Interventions

DRUG

No Results Yet

NCT07209228 | RECRUITING | NA

60 participants

Haptics in Virtual Reality

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-12-01
Completion:: 2028-12-23

Conditions

Literacy
Literacy-language Intervention
Haptics

Interventions

BEHAVIORAL

No Results Yet

NCT07206628 | RECRUITING

200 participants

Real-world Study to Assess Adherence to IOP Lowering Therapy in Patients With Glaucoma or Ocular Hypertension Using CONNECTDROP®

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-09-19
Completion:: 2027-09-30

Conditions

Adherence to Glaucoma Therapy

No Results Yet

NCT07205068 | RECRUITING | NA

100 participants

Improved Outcomes With Pre-Procedure Shockwave IVL of Common Femoral Artery Access Site Prior to Large Bore Access and Pre-Closure

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-10-04
Completion:: 2028-10-04

Conditions

Aortic Stenosis

Interventions

DEVICE
PROCEDURE

No Results Yet

NCT07202247 | RECRUITING | PHASE2

60 participants

Metabolic Interventions (Time-Restricted Eating, GLP1 Receptor Agonist, and Heart Healthy Diet) to Improve Cardiometabolic Health in Prostate Cancer Patients During Androgen Deprivation Therapy, IMPACT-ADT Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-11-05
Completion:: 2028-04-09

Conditions

Prostate Carcinoma
Recurrent Prostate Carcinoma

Interventions

DRUG
BEHAVIORAL
PROCEDURE
OTHER
RADIATION

No Results Yet

NCT07185451 | RECRUITING | NA

30 participants

Efficacy and Safety of Transcranial Alternating Current Stimulation (tACS) Combined With Stable Medication in Adolescents With Depression

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-10-01
Completion:: 2027-03-30

Conditions

Depression - Major Depressive Disorder

Interventions

DEVICE

No Results Yet

NCT07180355 | RECRUITING | PHASE1

10 participants

A Study of SGT-212 Gene Therapy in Friedreich's Ataxia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-10-22
Completion:: 2028-03-21

Conditions

Friedreich's Ataxia (FA)

Interventions

DRUG

No Results Yet

NCT07176689 | RECRUITING | PHASE4

50 participants

Nirogacestat in Premenopausal Females With Desmoid Tumor/Aggressive Fibromatosis (DT/AF)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-09-17
Completion:: 2031-02-26

Conditions

Desmoid Tumor
Aggressive Fibromatosis

Interventions

DRUG

No Results Yet

NCT07173101 | TERMINATED | PHASE2

7 participants

Clinical Investigation of the Effects of Semiconductor Embedded Therapeutic Garments on Cancer-related Cognitive Impairment in Breast and Gynecological Cancer Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-11-07
Completion:: 2026-07-03

Conditions

Breast Cancer
Gynecologic Cancer
Cancer-related Cognitive Difficulties

Interventions

DEVICE

No Results Yet

NCT07170553 | RECRUITING | NA

30 participants

Relationship Enhancement Digital Game

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-05-15
Completion:: 2027-04-30

Conditions

Parent-Child Relations
Parenting
Attachment Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT07166406 | RECRUITING | PHASE3

226 participants

Testing Immunotherapy With or Without Stereotactic Body Radiation Therapy in Patients With Advanced Liver Cancer, HELIO-RT Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-02-26
Completion:: 2029-03-10

Conditions

Advanced Hepatocellular Carcinoma
Stage III Hepatocellular Carcinoma AJCC v8
Stage IV Hepatocellular Carcinoma AJCC v8

Interventions

BIOLOGICAL
PROCEDURE
OTHER
RADIATION

No Results Yet

NCT07166133 | RECRUITING | NA

125 participants

GORE® TAG® Thoracic Branch Endoprosthesis Zone 0/1 Post-Approval Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-03-02
Completion:: 2028-07-31

Conditions

Aortic Arch Dissection
Aortic Arch Aneurysm

Interventions

DEVICE

No Results Yet

NCT07161700 | ENROLLING_BY_INVITATION | PHASE2

360 participants

An Open-Label Extension Study to Evaluate the Safety and Tolerability of SPT-300 (GlyphAllo) in Participants With Major Depressive Disorder, With or Without Anxious Distress (BUOY-1 OLE Study)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-09-02
Completion:: 2027-05-31

Conditions

Major Depressive Disorder (MDD)
Major Depressive Disorder With Anxious Distress

Interventions

DRUG

No Results Yet

NCT07157033 | RECRUITING | PHASE1/PHASE2

36 participants

A Phase 1 Study to Evaluate Safety and Efficacy of XER-001 (Amifostine for Nasoduodenal Delivery) in Combination With Sterotactic Body Radiotherapy for Treatment in Patients With Locally Advanced Pancreatic Cancer.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-01-01
Completion:: 2029-07-31

Conditions

Locally Advanced Pancreatic Adenocarcinoma
Locally Advanced Pancreas Cancer
Locally Advanced Pancreatic Ductal Adenocarcinoma

Interventions

DRUG

No Results Yet

NCT07149870 | RECRUITING | NA

432 participants

Pain Management Teams Using Whole Health to Optimize Function and Safety in Veterans: The TEAMWORK Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-11-20
Completion:: 2029-10-01

Conditions

Chronic Pain

Interventions

OTHER

No Results Yet

NCT07149272 | COMPLETED | NA

153 participants

Lactate Kinetics After Multimodal Exercise and Adjunctive Virtual Reality Exercise in Hospitalized Geriatric Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2024-02-16
Completion:: 2025-05-30

Conditions

Fatigue
Lactate
Frailty
Sarcopenia in Elderly
Quality of Life

Interventions

DEVICE

No Results Yet

NCT07148713 | ACTIVE_NOT_RECRUITING | NA

60 participants

Pilot of Continuous Glucose Monitor-Augmented Food Is Medicine

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-09-19
Completion:: 2026-12-31

Conditions

Nutrition
Type 2 Diabetes
T2DM
T2DM (Type 2 Diabetes Mellitus)
Diabetes Education
Diabetes Type 2
Diabetes Mellitis

Interventions

BEHAVIORAL

No Results Yet

NCT07146022 | ACTIVE_NOT_RECRUITING | PHASE3

552 participants

Safety and Efficacy of VDPHL01 in Females With Androgenetic Alopecia (AGA)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-07-25
Completion:: 2027-06-30

Conditions

Androgenetic Alopecia (AGA)
Androgenetic Alopecia
AGA
Female Androgenetic Alopecia
Hair Loss

Interventions

DRUG

No Results Yet

NCT07144826 | RECRUITING | EARLY_PHASE1

161 participants

Effects of a Probiotic Intervention on the Gut and Vaginal Microbiome in Patients With Advanced or Recurrent Ovarian Cancer Undergoing Treatment With Platinum Chemotherapy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-03-06
Completion:: 2027-07-09

Conditions

Advanced Ovarian Carcinoma
Recurrent Ovarian Carcinoma
Stage II Ovarian Cancer AJCC v8
Stage III Ovarian Cancer AJCC v8
Stage IV Ovarian Cancer AJCC v8

Interventions

PROCEDURE
DRUG
DIETARY_SUPPLEMENT
OTHER

No Results Yet

NCT07140016 | RECRUITING | PHASE1

40 participants

A Study of Gilteritinib in Adults With Advanced ALK-positive Non-small Cell Lung Cancer (NSCLC)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-09-22
Completion:: 2029-12-31

Conditions

Non-small Cell Lung Cancer (NSCLC)
Anaplastic Lymphoma Kinase (ALK) Positive

Interventions

DRUG

No Results Yet

NCT07139990 | RECRUITING | PHASE1

105 participants

Personalized Radiotherapy for Individualized Treatment Strategies and Monitoring (PRISM)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-10-28
Completion:: 2030-09-01

Conditions

Small Cell Lung Cancer Extensive Stage
Brain Metastases
Solid Tumor, Adult
Thoracic Cancer
Sarcoma,Soft Tissue
HNPCC

Interventions

RADIATION

No Results Yet

NCT07137624 | RECRUITING | NA

20 participants

Motor Imagery and Action Observation for Gait Function in MS

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-01-03
Completion:: 2026-08-31

Conditions

Multiple Sclerosis

Interventions

BEHAVIORAL

No Results Yet

NCT07134179 | COMPLETED

25 participants

Insufficient Regional Anesthesia for Cesarean Section: Mothers' Experiences A Qualitative Study

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-08-15
Completion:: 2026-04-01

Conditions

Caesarean Section
Regional Anesthesia

Interventions

OTHER

No Results Yet

NCT07133880 | RECRUITING | PHASE4

72 participants

Compare the Effects of Nebulizer Versus Inhaler Based Therapy for COPD Using Long-acting Bronchodilators

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2023-12-05
Completion:: 2026-12-01

Conditions

COPD (Chronic Obstructive Pulmonary Disease)

Interventions

DRUG

No Results Yet

NCT07131371 | ACTIVE_NOT_RECRUITING

2500 participants

Stratification, Management, and Guidance of Hypertrophic Cardiomyopathy Patients Using Hybrid Digital Twin Solutions

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-17
Start Date:: 2024-01-15
Completion:: 2026-12-31

Conditions

HCM - Hypertrophic Cardiomyopathy

No Results Yet

NCT07123779 | RECRUITING | PHASE1/PHASE2

126 participants

HS235 Study in Obese Participants With Pulmonary Hypertension and Heart Failure With Preserved Ejection Fraction (HFpEF)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-08-31
Completion:: 2029-01-31

Conditions

Pulmonary Hypertension
Heart Failure With Preserved Ejection Fraction

Interventions

BIOLOGICAL
OTHER

No Results Yet

NCT07121894 | RECRUITING | NA

30 participants

Ketogenic Intervention for Bipolar Depression

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-08-12
Completion:: 2028-12-31

Conditions

Bipolar Depression

Interventions

BEHAVIORAL

No Results Yet

NCT07116941 | COMPLETED | NA

124 participants

Multisensory and Cognitive Interventions in the ICU: Effects on Health and Recovery

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-08-01
Completion:: 2026-08-13

Conditions

Coronary Artery Bypass Graft (CABG)
Cardiac Surgery Subjects
Postoperative Care

Interventions

BEHAVIORAL

No Results Yet

NCT07112404 | RECRUITING | NA

42 participants

Pain Intervention With Needling: Pilot Of Integrated Neuromodulation Techniques

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-10-23
Completion:: 2027-08-31

Conditions

Pain
Back Pain
Lower Back Pain
Quality of Life

Interventions

OTHER

No Results Yet

NCT07106970 | RECRUITING | NA

640 participants

PVI Alone vs PVI and Linear Ablation for Persistent Atrial Fibrillation (PROMPT AF II)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-08-28
Completion:: 2027-12-30

Conditions

Persistent Atrial Fibrillation

Interventions

PROCEDURE

No Results Yet

NCT07105059 | RECRUITING | PHASE1

18 participants

A Study of Teclistamab and Mezigdomide in People With Multiple Myeloma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-08-08
Completion:: 2028-08-08

Conditions

Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT07102212 | SUSPENDED | NA

120 participants

Telemedicine-mHealth Symptom Cluster Intervention for Advanced Cancer Patients: Finding Our Center Under Stress (FOCUS)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-11-15
Completion:: 2028-08-31

Conditions

Lung Cancer
Breast Cancer
Prostate Cancer
Multiple Myeloma
Melanoma

Interventions

BEHAVIORAL

No Results Yet

NCT07092020 | COMPLETED | NA

220 participants

Extended Depth of Focus (EDF) Intraocular Lens (IOL) Versus Monofocal Intracoular Lens (IOL)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-10-01
Completion:: 2026-07-27

Conditions

Cataract Senile

Interventions

DEVICE

No Results Yet

NCT07091864 | RECRUITING | NA

116 participants

Continuous Glucose Monitoring for the Management of Hyperglycemia in Patients With Glioblastoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-07-29
Completion:: 2027-11-30

Conditions

Glioblastoma, IDH-Wildtype
WHO Grade 4 Glioma

Interventions

OTHER
PROCEDURE

No Results Yet

NCT07087951 | RECRUITING | NA

70 participants

Efficacy of Gamma Auditory Stimulation for Cognitive Decline in Older Adults (Study 1)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-11-14
Completion:: 2028-09-01

Conditions

EEG Brain Oscillations
Alzheimer's Disease (AD) and Related Disorders
Cognitive Dysfunction

Interventions

DEVICE

No Results Yet

NCT07085767 | RECRUITING | PHASE3

1000 participants

Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/HER2- Advanced Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-11-03
Completion:: 2028-12-31

Conditions

Breast Cancer
Locally Advanced Breast Cancer
Metastatic Breast Cancer
ER Positive Breast Cancer
HER2 Negative Breast Carcinoma

Interventions

DRUG

No Results Yet

NCT07082725 | RECRUITING | PHASE3

72 participants

A Study to Evaluate the Safety and Efficacy of Oral Nizubaglustat (AZ-3102) in Late-infantile and Juvenile Forms of Niemann-Pick Type C Disease (NPC)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-06-30
Completion:: 2028-05-14

Conditions

Niemann-Pick Type C Disease

Interventions

DRUG

No Results Yet