Clinical Trials Updated in 2026

NCT07140016 | RECRUITING | PHASE1

40 participants

A Study of Gilteritinib in Adults With Advanced ALK-positive Non-small Cell Lung Cancer (NSCLC)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-09-22
Completion:: 2029-12-31

Conditions

Non-small Cell Lung Cancer (NSCLC)
Anaplastic Lymphoma Kinase (ALK) Positive

Interventions

DRUG

No Results Yet

NCT07139990 | RECRUITING | PHASE1

105 participants

Personalized Radiotherapy for Individualized Treatment Strategies and Monitoring (PRISM)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-10-28
Completion:: 2030-09-01

Conditions

Small Cell Lung Cancer Extensive Stage
Brain Metastases
Solid Tumor, Adult
Thoracic Cancer
Sarcoma,Soft Tissue
HNPCC

Interventions

RADIATION

No Results Yet

NCT07137624 | RECRUITING | NA

20 participants

Motor Imagery and Action Observation for Gait Function in MS

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-01-03
Completion:: 2026-08-31

Conditions

Multiple Sclerosis

Interventions

BEHAVIORAL

No Results Yet

NCT07134179 | COMPLETED

25 participants

Insufficient Regional Anesthesia for Cesarean Section: Mothers' Experiences A Qualitative Study

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-08-15
Completion:: 2026-04-01

Conditions

Caesarean Section
Regional Anesthesia

Interventions

OTHER

No Results Yet

NCT07133880 | RECRUITING | PHASE4

72 participants

Compare the Effects of Nebulizer Versus Inhaler Based Therapy for COPD Using Long-acting Bronchodilators

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2023-12-05
Completion:: 2026-12-01

Conditions

COPD (Chronic Obstructive Pulmonary Disease)

Interventions

DRUG

No Results Yet

NCT07131371 | ACTIVE_NOT_RECRUITING

2500 participants

Stratification, Management, and Guidance of Hypertrophic Cardiomyopathy Patients Using Hybrid Digital Twin Solutions

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-17
Start Date:: 2024-01-15
Completion:: 2026-12-31

Conditions

HCM - Hypertrophic Cardiomyopathy

No Results Yet

NCT07123779 | RECRUITING | PHASE1/PHASE2

126 participants

HS235 Study in Obese Participants With Pulmonary Hypertension and Heart Failure With Preserved Ejection Fraction (HFpEF)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-08-31
Completion:: 2029-01-31

Conditions

Pulmonary Hypertension
Heart Failure With Preserved Ejection Fraction

Interventions

BIOLOGICAL
OTHER

No Results Yet

NCT07121894 | RECRUITING | NA

30 participants

Ketogenic Intervention for Bipolar Depression

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-08-12
Completion:: 2028-12-31

Conditions

Bipolar Depression

Interventions

BEHAVIORAL

No Results Yet

NCT07116941 | COMPLETED | NA

124 participants

Multisensory and Cognitive Interventions in the ICU: Effects on Health and Recovery

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-08-01
Completion:: 2026-08-13

Conditions

Coronary Artery Bypass Graft (CABG)
Cardiac Surgery Subjects
Postoperative Care

Interventions

BEHAVIORAL

No Results Yet

NCT07112404 | RECRUITING | NA

42 participants

Pain Intervention With Needling: Pilot Of Integrated Neuromodulation Techniques

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-10-23
Completion:: 2027-08-31

Conditions

Pain
Back Pain
Lower Back Pain
Quality of Life

Interventions

OTHER

No Results Yet

NCT07106970 | RECRUITING | NA

640 participants

PVI Alone vs PVI and Linear Ablation for Persistent Atrial Fibrillation (PROMPT AF II)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-08-28
Completion:: 2027-12-30

Conditions

Persistent Atrial Fibrillation

Interventions

PROCEDURE

No Results Yet

NCT07105059 | RECRUITING | PHASE1

18 participants

A Study of Teclistamab and Mezigdomide in People With Multiple Myeloma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-08-08
Completion:: 2028-08-08

Conditions

Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT07102212 | SUSPENDED | NA

120 participants

Telemedicine-mHealth Symptom Cluster Intervention for Advanced Cancer Patients: Finding Our Center Under Stress (FOCUS)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-11-15
Completion:: 2028-08-31

Conditions

Lung Cancer
Breast Cancer
Prostate Cancer
Multiple Myeloma
Melanoma

Interventions

BEHAVIORAL

No Results Yet

NCT07092020 | COMPLETED | NA

220 participants

Extended Depth of Focus (EDF) Intraocular Lens (IOL) Versus Monofocal Intracoular Lens (IOL)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-10-01
Completion:: 2026-07-27

Conditions

Cataract Senile

Interventions

DEVICE

No Results Yet

NCT07091864 | RECRUITING | NA

116 participants

Continuous Glucose Monitoring for the Management of Hyperglycemia in Patients With Glioblastoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-07-29
Completion:: 2027-11-30

Conditions

Glioblastoma, IDH-Wildtype
WHO Grade 4 Glioma

Interventions

OTHER
PROCEDURE

No Results Yet

NCT07087951 | RECRUITING | NA

70 participants

Efficacy of Gamma Auditory Stimulation for Cognitive Decline in Older Adults (Study 1)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-11-14
Completion:: 2028-09-01

Conditions

EEG Brain Oscillations
Alzheimer's Disease (AD) and Related Disorders
Cognitive Dysfunction

Interventions

DEVICE

No Results Yet

NCT07085767 | RECRUITING | PHASE3

1000 participants

Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/HER2- Advanced Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-11-03
Completion:: 2028-12-31

Conditions

Breast Cancer
Locally Advanced Breast Cancer
Metastatic Breast Cancer
ER Positive Breast Cancer
HER2 Negative Breast Carcinoma

Interventions

DRUG

No Results Yet

NCT07082725 | RECRUITING | PHASE3

72 participants

A Study to Evaluate the Safety and Efficacy of Oral Nizubaglustat (AZ-3102) in Late-infantile and Juvenile Forms of Niemann-Pick Type C Disease (NPC)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-06-30
Completion:: 2028-05-14

Conditions

Niemann-Pick Type C Disease

Interventions

DRUG

No Results Yet

NCT07075432 | COMPLETED

84 participants

Preoperative and Postoperative Comparison of Two Nerve Blocks in Intertrochanteric Fracture Surgery

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-05-19
Completion:: 2025-11-19

Conditions

Postoperative Pain
Fracture Femur

No Results Yet

NCT07075276 | RECRUITING | NA

32 participants

Liquid Phase Concentrated Growth Factor Versus Conventional Arthrocentesis in Temporomandibular Disc Displacement

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-10-01
Completion:: 2026-11-01

Conditions

Temporomandibular Disorders (TMD)
Internal Derangement of the Tempromandibular Joint
Anterior Disc Displacement

Interventions

PROCEDURE

No Results Yet

NCT07073326 | COMPLETED | NA

16 participants

Effects of Normobaric Hypoxic Training in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-09-01
Completion:: 2026-07-13

Conditions

MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease
Normobaric Hypoxia

Interventions

OTHER

No Results Yet

NCT07070362 | RECRUITING

3000 participants

Digital Early Warning System for Acute Lung Injury in Liver Surgery

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-17
Start Date:: 2024-11-01
Completion:: 2027-06-01

Conditions

Acute Lung Injury(ALI)
Liver Cirrhosis
ARDS, Human
MASLD
MASLD/MASH (Metabolic Dysfunction-Associated Steatotic Liver Disease / Metabolic Dysfunction-Associated Steatohepatitis)
NAFLD (Nonalcoholic Fatty Liver Disease)
Liver Cancer, Adult

No Results Yet

NCT07069712 | RECRUITING | PHASE2

100 participants

A Study of Novel Agents or Combinations as Perioperative Treatment in Participants With Locally Advanced Resectable Gastroesophageal Adenocarcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-07-17
Completion:: 2027-11-03

Conditions

Gastroesophageal Adenocarcinoma

Interventions

DRUG

No Results Yet

NCT07066826 | RECRUITING | PHASE2/PHASE3

720 participants

Clinical Study to Evaluate the Efficacy and Safety of Huperzine A Controlled-Release Tablets in Patients With Mild-to-Moderate Dementia of the Alzheimer's Type

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-08-29
Completion:: 2028-08-15

Conditions

Alzheimer Dementia

Interventions

DRUG

No Results Yet

NCT07065240 | RECRUITING | PHASE2

360 participants

A Study to Evaluate the Efficacy and Safety of SPT-300 (GlyphAllo) in Participants With Major Depressive Disorder, With or Without Anxious Distress (BUOY-1 Study)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-06-19
Completion:: 2027-03-31

Conditions

Major Depressive Disorder (MDD)
Major Depressive Disorder With Anxious Distress

Interventions

DRUG

No Results Yet

NCT07063342 | RECRUITING | PHASE1

236 participants

A Study to Evaluate Novel KarX and KarT Prototypes Versus the KarXT and KarX-EC Reference Following Single Doses, Explore the Effect of Food After Multiple Doses of Selected Prototypes, and Evaluate Alternative Formulations of KarX and KarXT Following Single and Multiple Ascending Doses

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-06-27
Completion:: 2027-03-29

Conditions

Healthy Volunteers

Interventions

DRUG

No Results Yet

NCT07062588 | RECRUITING | PHASE2

80 participants

Osteogenesis Imperfecta Trial of AGA2115 for ADUlts With COL1A1 and/or COL1A2 GeNetic Variations (IDUN)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-12-12
Completion:: 2027-11-30

Conditions

Osteogenesis Imperfecta (OI)

Interventions

DRUG
OTHER

No Results Yet

NCT07059416 | COMPLETED | NA

44 participants

The Effect of Mindful Hand Hygiene Practice on Self-Care Perception and Self-Compassion Levels of Oncology Nurses; Mixed Design Example

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-01-10
Completion:: 2025-04-10

Conditions

Mindfulness Meditation
Selfcompassion

Interventions

BEHAVIORAL

No Results Yet

NCT07054385 | COMPLETED | NA

41 participants

I-CARE Rural Pilot: Intervention for Rural-Dwelling Dementia Caregivers

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-07-01
Completion:: 2026-07-05

Conditions

Caregiver Burden
Alzheimer Disease

Interventions

BEHAVIORAL

No Results Yet

NCT07047872 | RECRUITING | NA

50 participants

A 3D-Printed External Breast Prosthesis for the Improvement of Patient-reported Outcomes Among Breast Cancer Patients That Underwent a Mastectomy Without Reconstruction

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2024-11-05
Completion:: 2027-11-05

Conditions

Breast Carcinoma

Interventions

PROCEDURE
OTHER

No Results Yet

NCT07044466 | RECRUITING | NA

230 participants

Social Functioning in Opioid Use Disorder

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-08-13
Completion:: 2029-08-31

Conditions

Opioid Use Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT07040449 | RECRUITING | NA

192 participants

Stress Trajectories and Anhedonia in Adolescence Research Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-03-12
Completion:: 2030-02-28

Conditions

Anhedonia
Stress Response
Adolescent Development

Interventions

BEHAVIORAL

No Results Yet

NCT07038889 | NOT_YET_RECRUITING | NA

30 participants

Overground Virtual Reality (VR) Gait Rehabilitation for Traumatic Brain Injury (TBI)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-08-31
Completion:: 2027-06-30

Conditions

Traumatic Brain Injury

Interventions

DEVICE

No Results Yet

NCT07036718 | TERMINATED

6 participants

NIS PDC the Efficacy and Safety of Iptacopan in Adults in Routine Clinical Practice

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-07-29
Completion:: 2025-12-25

Conditions

Paroxysmal Nocturnal Hemoglobinuria

No Results Yet

NCT07027839 | RECRUITING | PHASE1

30 participants

Acute Effects of Alcohol on PET Imaging of Phosphodiesterase-4B (PDE4B)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-12-11
Completion:: 2028-02-22

Conditions

Alcohol Use Disorder

Interventions

DRUG

No Results Yet

NCT07021430 | RECRUITING | EARLY_PHASE1

300 participants

Focal Mass Drug Administration for the Prevention of Malaria in Pregnancy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-09-27
Completion:: 2028-09-30

Conditions

Malaria Prevention

Interventions

DRUG

No Results Yet

NCT07010705 | RECRUITING

100 participants

Digital Measures for Clinical Trial Endpoints in Huntington's Disease

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-06-20
Completion:: 2027-08-31

Conditions

Huntington Disease
Healthy

Interventions

DEVICE

No Results Yet

NCT07009860 | ACTIVE_NOT_RECRUITING | PHASE2

121 participants

RESTORE TRIAL: Study of the Efficacy and Safety of Pemvidutide in the Treatment of Alcohol-Associated Liver Disease (ALD)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-06-16
Completion:: 2027-09-30

Conditions

Alcohol-associated Liver Disease

Interventions

DRUG
OTHER

No Results Yet

NCT07006935 | RECRUITING | NA

30 participants

REACH Study (Recovery Environments: Assessing Cognitive & Brain Health in Community Mental Health)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2026-08-30
Completion:: 2028-01-30

Conditions

Schizophrenia
Schizo Affective Disorder
Schizophreniform Disorders

Interventions

BEHAVIORAL

No Results Yet

NCT06998641 | RECRUITING | NA

62 participants

EFFECTIVITY OF CHITOSAN COVERED GAUZE IN POSTPARTUM HEMORRHAGIC OBSTETRIC LACERATIONS

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-17
Start Date:: 2025-03-01
Completion:: 2027-03-31

Conditions

Effectiveness of Chitosan Covered Gauze to Stop Bleeding in Post-partum Tears
Comparison of the Effect of Chitosan Covered Gauze With Suturing in Terms of Hemostasis in Post-partum Haemorrhagic Tears

Interventions

PROCEDURE

No Results Yet