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Liquid Phase Concentrated Growth Factor Versus Conventional Arthrocentesis in Temporomandibular Disc Displacement

NCT07075276 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 32

Last updated 2026-03-11

No results posted yet for this study

Summary

This study aims to rigorously assess the effectiveness of LPCGF in the management of internal disc displacement in patients with TMD through a randomized clinical trial. By comparing LPCGF therapy with conventional arthrocentesis, this research looks to provide robust evidence on the efficacy, safety, and potential role of (LPCGF) as an alternative therapeutic choice for IDD.

Conditions

  • Temporomandibular Disorders (TMD)
  • Internal Derangement of the Tempromandibular Joint
  • Anterior Disc Displacement

Interventions

PROCEDURE

Liquid Phase Concentrated Growth Factor

16 patients with anterior disc displacement with or without reduction randomly allocated to be treated with injection of liquid phase concentrated growth factor

PROCEDURE

Conventional arthrocentesis

16 patients with anterior disc displacement with or without reduction randomly allocated to be treated with conventional arthrocentesis

Sponsors & Collaborators

  • Horus University

    lead OTHER

Principal Investigators

  • Mohamed Ali Habib, Teaching Assistant · Horus University in Egypt - Faculty of dentistry

  • Eman AbdElsalam Yousef, Ass. prof · Horus University in Egypt- Faculty of dentistry

  • Ahmed Khalil, lecturer · Horus University in Egypt - Faculty of dentistry

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
45 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-10-01
Primary Completion
2026-05-01
Completion
2026-06-01

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07075276 on ClinicalTrials.gov