Clinical Trials

NCT04776941 | RECRUITING | NA

414 participants

Expressive Writing for the Management of Stress in Cancer Survivors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2020-08-07

Completion:

2028-12-31

Conditions

• Hematopoietic and Lymphoid Cell Neoplasm
• Malignant Solid Neoplasm

Interventions

• BEHAVIORAL
• OTHER

No Results Yet

NCT04775368 | COMPLETED | NA

598 participants

Fibromyalgia Syndrome in France: The Role of Assessment and Management of Sleep Disorders

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2021-04-01

Completion:

2023-03-07

Conditions

• Fibromyalgia

Interventions

• OTHER

No Results Yet

NCT04774718 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

42 participants

A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Alectinib in Pediatric Participants With ALK Fusion-Positive Solid or CNS Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2021-09-14

Completion:

2032-02-28

Conditions

• ALK Fusion-positive Solid or CNS Tumors

Interventions

• DRUG

No Results Yet

NCT04743141 | RECRUITING | PHASE3

600 participants

Long-term Safety Study of Rimegepant in Pediatric Subjects for the Acute Treatment of Migraine

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2021-04-28

Completion:

2030-07-31

Conditions

• Acute Treatment of Migraine

Interventions

• DRUG

No Results Yet

NCT04738825 | ACTIVE_NOT_RECRUITING | NA

526 participants

Promoting HIV Risk Reduction Among People Who Inject Drugs: A Stepped Care Approach Using Contingency Management With PrEP Adherence and Support Services

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2021-10-04

Completion:

2026-07-31

Conditions

• Opioid-use Disorder
• HIV Prevention Program

Interventions

• BEHAVIORAL

No Results Yet

NCT04736706 | ACTIVE_NOT_RECRUITING | PHASE3

1854 participants

A Study of Pembrolizumab (MK-3475) in Combination With Belzutifan (MK-6482) and Lenvatinib (MK-7902), or Pembrolizumab/Quavonlimab (MK-1308A) in Combination With Lenvatinib, Versus Pembrolizumab and Lenvatinib, for Treatment of Advanced Clear Cell Renal Cell Carcinoma (MK-6482-012)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2021-04-14

Completion:

2026-02-04

Conditions

• Carcinoma, Renal Cell

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT04706026 | ACTIVE_NOT_RECRUITING | NA

18 participants

A Pilot Study of Local Anesthesia for Inguinal Hernia Surgery in Older Adults

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2024-10-23

Completion:

2026-08-31

Conditions

• Inguinal Hernia
• Anesthesia, Local

Interventions

• OTHER

No Results Yet

NCT04675307 | COMPLETED

50 participants

Multimodal, Task-Aware Movement Assessment and Control: Clinic to the Home

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-14

Start Date:

2021-02-17

Completion:

2023-12-01

Conditions

• Frailty

No Results Yet

NCT04663724 | RECRUITING | NA

80 participants

Computer - Based Treatment for Social Anxiety Disorder

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2021-02-15

Completion:

2026-11-30

Conditions

• Social Anxiety Disorder

Interventions

• BEHAVIORAL

No Results Yet

NCT04649242 | RECRUITING | PHASE3

2100 participants

Randomized Study in Children and Adolescents With Migraine: Acute Treatment

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2021-01-15

Completion:

2029-01-09

Conditions

• Pediatric Migraine

Interventions

• DRUG

No Results Yet

NCT04591951 | COMPLETED | NA

108 participants

Family Navigation to Improve ADHD Treatment Adherence for Minority Children

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2021-05-14

Completion:

2026-07-30

Conditions

• Attention Deficit Hyperactivity Disorder

Interventions

• BEHAVIORAL
• OTHER

No Results Yet

NCT04567303 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

177 participants

Study of Zifibancimig in Participants With Neovascular Age-related Macular Degeneration

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2020-10-28

Completion:

2026-08-25

Conditions

• Macular Degeneration

Interventions

• DRUG
• DEVICE

No Results Yet

NCT04550481 | ACTIVE_NOT_RECRUITING | PHASE2

35 participants

Role of Lisinopril in Preventing the Progression of Non-Alcoholic Fatty Liver Disease, RELIEF-NAFLD Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2021-05-11

Completion:

2025-08-08

Conditions

• Hepatocellular Carcinoma
• Nonalcoholic Steatohepatitis

Interventions

• PROCEDURE
• DRUG
• OTHER

Results Available

NCT04537871 | ACTIVE_NOT_RECRUITING

350 participants

Cardiovascular Reserve Evaluation in Survivors of Transplant, CREST Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-14

Start Date:

2020-11-18

Completion:

2027-05-25

Conditions

• Acute Lymphoblastic Leukemia
• Acute Myeloid Leukemia
• Hematopoietic and Lymphoid Cell Neoplasm
• Hodgkin Lymphoma
• Myelodysplastic Syndrome
• Non-Hodgkin Lymphoma
• Plasma Cell Myeloma

Interventions

• PROCEDURE
• OTHER

No Results Yet

NCT04524871 | RECRUITING | PHASE1/PHASE2

518 participants

A Study Evaluating the Efficacy and Safety of Multiple Immunotherapy-Based Treatment Combinations in Patients With Advanced Liver Cancers (Morpheus-Liver)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2020-11-01

Completion:

2027-07-30

Conditions

• Advanced Liver Cancers

Interventions

• DRUG

No Results Yet

NCT04436640 | ACTIVE_NOT_RECRUITING | PHASE3

508 participants

A Study to Evaluate the Long-term Safety, Tolerability and Efficacy of Bimekizumab in Subjects With Active Axial Spondyloarthritis Including Ankylosing Spondylitis and Nonradiographic Axial Spondyloarthritis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2020-06-16

Completion:

2026-08-07

Conditions

• Axial Spondyloarthritis
• Ankylosing Spondylitis
• r-axSpa
• Nr-axSpa

Interventions

• DRUG

No Results Yet

NCT04401020 | TERMINATED | PHASE1

47 participants

First-in-human Single Agent Study of SAR442257 in RRMM and RR-NHL

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2020-07-24

Completion:

2024-03-02

Conditions

• Neoplasm Malignant

Interventions

• DRUG

No Results Yet

NCT04381897 | NOT_YET_RECRUITING | PHASE2

10 participants

Use of N-Acetylcysteine in the Treatment of Repetitive and Self-Injurious Behaviors in Cornelia de Lange Syndrome

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2026-11-01

Completion:

2027-05-01

Conditions

• Cornelia de Lange Syndrome

Interventions

• DRUG
• OTHER

No Results Yet

NCT04367675 | ACTIVE_NOT_RECRUITING | PHASE1

44 participants

INO 5401 Vaccination in BRCA1/2 Mutation Carriers

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2021-04-20

Completion:

2026-12-31

Conditions

• BRCA1/2 Mutation

Interventions

• DRUG
• DEVICE

No Results Yet

NCT04357080 | COMPLETED

266 participants

Factors Predicting Urethral Stricture Recurrence After Dorsal Onlay Augmented, Buccal Mucosal Graft Urethroplasty

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-14

Start Date:

2020-07-15

Completion:

2020-08-15

Conditions

• Urethral Stricture

Interventions

• PROCEDURE

No Results Yet

NCT04346134 | COMPLETED | NA

72 participants

Mini- Percutaneous Nephrolithotomy Versus Extracorporeal Shock Wave Lithotripsy for High Density Renal Stones

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2020-07-14

Completion:

2020-12-01

Conditions

• Renal Stone
• Extracorporeal Shockwave Lithotripsy
• Percutaneous Nephrolithotomy

Interventions

• PROCEDURE

No Results Yet

NCT04336150 | COMPLETED | NA

80 participants

Pelvic Floor Muscle Contraction During Hypopressive Exercise in Women With Pelvic Floor Dysfunction

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2019-02-10

Completion:

2024-12-20

Conditions

• Pelvic Floor Disorders

Interventions

• OTHER

No Results Yet

NCT04324619 | ACTIVE_NOT_RECRUITING | NA

6000 participants

iLookOut for Child Abuse: Micro-learning to Improve Knowledge Retention

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2024-04-10

Completion:

2027-08-31

Conditions

• Child Abuse

Interventions

• OTHER

No Results Yet

NCT04321876 | ACTIVE_NOT_RECRUITING

778 participants

Evaluation of a Collaborative Behavioral Health Program Implementation in Primary Care

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-14

Start Date:

2018-09-01

Completion:

2024-01-31

Conditions

• Depression

Interventions

• BEHAVIORAL

No Results Yet

NCT04302259 | COMPLETED | NA

3 participants

Intelligent Spine Interface, Clinical (ISI-C)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2021-09-01

Completion:

2025-06-30

Conditions

• Spinal Cord Injury

Interventions

• DEVICE

No Results Yet

NCT04267848 | RECRUITING | PHASE3

1210 participants

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2020-06-16

Completion:

2027-01-31

Conditions

• Lung Non-Small Cell Carcinoma
• Lung Non-Small Cell Squamous Carcinoma
• Lung Non-Squamous Non-Small Cell Carcinoma
• Stage II Lung Cancer AJCC v8
• Stage IIIA Lung Cancer AJCC v8
• Stage IIIB Lung Cancer AJCC v8

Interventions

• PROCEDURE
• DRUG
• OTHER
• BIOLOGICAL

No Results Yet

NCT04261478 | RECRUITING | NA

458 participants

Endovascular Acute Stroke Intervention - Tandem OCclusion Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2020-08-31

Completion:

2027-05-31

Conditions

• Stroke, Acute
• Carotid Stenosis
• Carotid Artery Diseases

Interventions

• DEVICE
• DRUG

No Results Yet

NCT04248192 | ACTIVE_NOT_RECRUITING | PHASE1

8 participants

Evaluate the Safety, Immunologic, and Virologic Responses of Donor Derived (DD) HIV-Specific T-cells (HST) in HIV-infected Individuals Following Allogeneic Bone Marrow Transplantation (alloRESIST)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2020-05-01

Completion:

2026-11-30

Conditions

• HIV-Infected Individuals

Interventions

• BIOLOGICAL

No Results Yet

NCT04235777 | ACTIVE_NOT_RECRUITING | PHASE1

22 participants

Bintrafusp Alfa (M7824) and PDS01ADC Alone and in Combination With Stereotactic Body Radiation Therapy (SBRT) in Adults With Metastatic Non-Prostate Genitourinary Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2020-07-13

Completion:

2026-08-31

Conditions

• Urothelial Cancer
• Bladder Cancer
• Genitourinary Cancer
• Urogenital Neoplasms
• Urogenital Cancer

Interventions

• RADIATION
• DRUG

No Results Yet

NCT04230759 | ACTIVE_NOT_RECRUITING | PHASE2

180 participants

Radiochemotherapy +/- Durvalumab for Locally-advanced Anal Carcinoma. A Multicenter, Randomized, Phase II Trial of the German Anal Cancer Study Group

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2020-01-07

Completion:

2026-12-31

Conditions

• Anal Cancer
• Anal Carcinoma
• Anal Cancer Stage III
• Anal Cancer Stage II

Interventions

• DRUG
• RADIATION

No Results Yet

NCT04221893 | RECRUITING | NA

28 participants

Radiation Therapy for the Treatment of Metastatic Gastrointestinal Cancers

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2020-08-07

Completion:

2027-04-30

Conditions

• Stage IV Esophageal Adenocarcinoma
• Stage IV Esophageal Squamous Cell Carcinoma
• Stage IV Gastric Cancer
• Stage IV Adenocarcinoma of the Gastroesophageal Junction
• Stage IVA Esophageal Adenocarcinoma
• Stage IVA Esophageal Squamous Cell Carcinoma
• Stage IVA Gastric Cancer
• Stage IVA Adenocarcinoma of the Gastroesophageal Junction
• Stage IVB Esophageal Adenocarcinoma
• Stage IVB Esophageal Squamous Cell Carcinoma
• Stage IVB Gastric Cancer
• Stage IVB Gastroesophageal Junction Adenocarcinoma
• Metastatic Anal Canal Carcinoma
• Metastatic Colorectal Carcinoma
• Metastatic Esophageal Carcinoma
• Metastatic Gastric Carcinoma
• Metastatic Gastroesophageal Junction Adenocarcinoma
• Metastatic Hepatocellular Carcinoma
• Metastatic Malignant Digestive System Neoplasm
• Metastatic Small Intestinal Carcinoma
• Pancreatobiliary Carcinoma
• Pathologic Stage IV Gastric Cancer AJCC v8
• Pathologic Stage IVA Esophageal Adenocarcinoma AJCC v8
• Pathologic Stage IVA Esophageal Squamous Cell Carcinoma AJCC v8
• Pathologic Stage IVB Esophageal Adenocarcinoma AJCC v8
• Pathologic Stage IVB Esophageal Squamous Cell Carcinoma AJCC v8
• Pathologic Stage IVB Gastroesophageal Junction Adenocarcinoma AJCC v8
• Postneoadjuvant Therapy Stage IV Esophageal Squamous Cell Carcinoma AJCC v8
• Postneoadjuvant Therapy Stage IV Gastric Cancer AJCC v8
• Postneoadjuvant Therapy Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8
• Postneoadjuvant Therapy Stage IVA Esophageal Adenocarcinoma AJCC v8
• Postneoadjuvant Therapy Stage IVA Esophageal Squamous Cell Carcinoma AJCC v8
• Postneoadjuvant Therapy Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8
• Postneoadjuvant Therapy Stage IVB Esophageal Adenocarcinoma AJCC v8
• Postneoadjuvant Therapy Stage IVB Esophageal Squamous Cell Carcinoma AJCC V8
• Postneoadjuvant Therapy Stage IVB Gastroesophageal Junction Adenocarcinoma AJCC v8
• Stage IV Anal Cancer AJCC v8
• Stage IV Colorectal Cancer AJCC v8
• Stage IV Hepatocellular Carcinoma AJCC v8
• Stage IVA Colorectal Cancer AJCC v8
• Stage IVA Hepatocellular Carcinoma AJCC v8
• Stage IVB Colorectal Cancer AJCC v8
• Stage IVB Hepatocellular Carcinoma AJCC v8
• Stage IVC Colorectal Cancer AJCC v8

Interventions

• RADIATION

No Results Yet

NCT04173533 | COMPLETED | PHASE3

326 participants

Randomised Study of Oral Azacitidine vs Placebo Maintenance in AML or MDS Patients After Allo-SCT

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2019-06-14

Completion:

2026-04-29

Conditions

• Acute Myeloid Leukemia
• Myelodysplasia

Interventions

• DRUG

No Results Yet

NCT04163809 | NOT_YET_RECRUITING | NA

80 participants

The Role of Virtual Reality During Regional Anesthesia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2027-01-01

Completion:

2028-06-30

Conditions

• Anxiety
• Pain

Interventions

• DEVICE

No Results Yet

NCT04146051 | ACTIVE_NOT_RECRUITING | PHASE2

30 participants

Descartes-08 CAR-T Cells in Generalized Myasthenia Gravis (MG)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2019-12-04

Completion:

2026-01-05

Conditions

• Myasthenia Gravis, Generalized

Interventions

• DRUG

No Results Yet

NCT04115267 | RECRUITING

3600 participants

Attribution of Toxicities Due to Radiotherapy and Immuno-Biological Therapies

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-14

Start Date:

2019-09-13

Completion:

2030-09-30

Conditions

• Cancer
• Radiotherapy Side Effect

Interventions

• RADIATION

No Results Yet

NCT04104464 | RECRUITING

200 participants

Patient Reported Outcomes for Vascular Malformations EmbolizatioN (PROVEN)

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-14

Start Date:

2019-07-22

Completion:

2028-07-31

Conditions

• Vascular Malformations
• VM - Vascular Malformation

No Results Yet

NCT04073966 | RECRUITING

20 participants

MRI Biomarkers for Radiation-Induced Neurocognitive Decline Following SRS of Newly Diagnosed Brain Mets

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-14

Start Date:

2019-12-04

Completion:

2028-05-31

Conditions

• Brain Metastases
• Neurocognitive Deficit
• White Matter Alterations
• Radiation Exposure

No Results Yet

NCT04058639 | RECRUITING | NA

74 participants

Diabetic Foot Ulcers: Shorter Treatment Period Using Custom Felt Relief?

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2019-10-01

Completion:

2027-03-01

Conditions

• Diabetic Foot Ulcer

Interventions

• PROCEDURE

No Results Yet

NCT04015765 | COMPLETED | NA

376 participants

Hybrid-APC Margin Ablation to Prevent Post EMR Adenoma Recurrence

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-14

Start Date:

2019-08-26

Completion:

2024-12-13

Conditions

• Colorectal Cancer
• Polyp of Colon

Interventions

• PROCEDURE

No Results Yet

NCT04014829 | RECRUITING

436 participants

Evaluation of Central Sensitization, Fear-Avoidance, and Pain-Pressure Threshold With Chronic Pain After Hysterectomy

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-14

Start Date:

2019-07-23

Completion:

2027-12-31

Conditions

• Hysterectomy
• Chronic Pain
• Central Sensitisation
• Anxiety Depression

Interventions

• DIAGNOSTIC_TEST

No Results Yet