Clinical Trials Updated in 2026

NCT05083481 | TERMINATED | PHASE1

226 participants

A Study of ASP1570 Taken by Itself, or ASP1570 Taken Together With Either Pembrolizumab, Standard Therapies, or Both, in Adults With Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2021-10-19
Completion:: 2026-05-11

Conditions

Advanced Solid Tumors

Interventions

DRUG

No Results Yet

NCT05076617 | ENROLLING_BY_INVITATION | PHASE3

300 participants

A Study to Test the Safety and Tolerability of Staccato Alprazolam in Study Participants 12 Years of Age and Older With Stereotypical Prolonged Seizures

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2022-02-03
Completion:: 2028-11-30

Conditions

Stereotypical Prolonged Seizures

Interventions

DRUG

No Results Yet

NCT05043012 | RECRUITING | NA

258 participants

Diagnostic Performance Of Non-Endorectal Coil Multiparametric Magnetic Resonance Imaging Of Prostate With Flexible AIR Coil (DoNEMAC Study)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2022-07-18
Completion:: 2027-02-02

Conditions

Prostate Cancer

Interventions

DEVICE

No Results Yet

NCT05038098 | NOT_YET_RECRUITING | PHASE1

20 participants

Magnetic Sentinel Lymph Node Mapping in Gastric Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2026-12-31
Completion:: 2027-02-02

Conditions

Gastric Adenocarcinoma

Interventions

PROCEDURE
DRUG
OTHER

No Results Yet

NCT05025059 | ACTIVE_NOT_RECRUITING | NA

30 participants

Exercise During Chemotherapy in Older Women With Stage I-III Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2020-12-03
Completion:: 2026-12-31

Conditions

Anatomic Stage I Breast Cancer AJCC v8
Anatomic Stage IA Breast Cancer AJCC v8
Anatomic Stage IB Breast Cancer AJCC v8
Anatomic Stage II Breast Cancer AJCC v8
Anatomic Stage IIA Breast Cancer AJCC v8
Anatomic Stage IIB Breast Cancer AJCC v8
Anatomic Stage III Breast Cancer AJCC v8
Anatomic Stage IIIA Breast Cancer AJCC v8
Anatomic Stage IIIB Breast Cancer AJCC v8
Anatomic Stage IIIC Breast Cancer AJCC v8
Prognostic Stage I Breast Cancer AJCC v8
Prognostic Stage IA Breast Cancer AJCC v8
Prognostic Stage IB Breast Cancer AJCC v8
Prognostic Stage II Breast Cancer AJCC v8
Prognostic Stage IIA Breast Cancer AJCC v8
Prognostic Stage IIB Breast Cancer AJCC v8
Prognostic Stage III Breast Cancer AJCC v8
Prognostic Stage IIIA Breast Cancer AJCC v8
Prognostic Stage IIIB Breast Cancer AJCC v8
Prognostic Stage IIIC Breast Cancer AJCC v8

Interventions

PROCEDURE
OTHER

No Results Yet

NCT05025046 | COMPLETED

250 participants

NGS-based Thyroscan Genomic Classifier in the Diagnosis of Thyroid Nodules

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-14
Start Date:: 2021-09-01
Completion:: 2024-12-31

Conditions

Thyroid Nodule
Thyroid Cancer

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05014399 | RECRUITING

60 participants

Cognitive Impairment in Colorectal Cancer Patients Receiving Cytotoxic Chemotherapy

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-14
Start Date:: 2021-09-20
Completion:: 2028-10-31

Conditions

Neoplasm, Colorectal
Cognitive Impairment
Cognitive Dysfunction
Cognitive Change
Chemo-brain
Chemo Fog
Chemotherapy Effect
Cognitive Decline

No Results Yet

NCT04987229 | ENROLLING_BY_INVITATION | PHASE3

236 participants

Long-term Safety Extension Study of OLZ/SAM in Pediatric Subjects

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2021-10-22
Completion:: 2027-09-30

Conditions

Bipolar I Disorder
Schizophrenia

Interventions

DRUG

No Results Yet

NCT04967989 | RECRUITING | PHASE3

790 participants

Clarifying the Optimal Application of SLT Therapy Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2021-09-07
Completion:: 2027-06-30

Conditions

Glaucoma and Ocular Hypertension

Interventions

PROCEDURE

No Results Yet

NCT04948658 | RECRUITING

200 participants

Gonadal Tissue Freezing for Fertility Preservation in Individuals at Risk for Ovarian Dysfunction, Premature Ovarian Insufficiency and Clinically Indicated Gonadectomy

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-14
Start Date:: 2021-09-13
Completion:: 2030-07-31

Conditions

Turner Syndrome
Post-menarcheal Adolescents
Ovarian Disfunction
Galactosemia
Variations in Sex Characteristics
Differences in Sex Development

No Results Yet

NCT04937829 | COMPLETED | PHASE1

59 participants

A Study to Test How Well Different Doses of BI 1569912 Are Tolerated and How Well They Work in People With Depression Who Take Anti-depressive Medication

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2021-07-20
Completion:: 2023-11-16

Conditions

Depressive Disorder, Major

Interventions

DRUG

Results Available

NCT04920344 | ACTIVE_NOT_RECRUITING | PHASE2

15 participants

Swallowing Outcomes and Circulating Tumor DNA in Patients With HPV Related Oropharyngeal Cancer Treated With Transoral Surgery and Reduced Intensity Adjuvant Therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2021-05-19
Completion:: 2026-05-30

Conditions

Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
Oropharyngeal Human Papillomavirus-Positive Squamous Cell Carcinoma

Interventions

PROCEDURE
RADIATION
DRUG
OTHER
DIAGNOSTIC_TEST

No Results Yet

NCT04896073 | COMPLETED | PHASE2

16 participants

Superenhancer Inhibitor Minnelide in Advanced Refractory Adenosquamous Carcinoma of the Pancreas (ASCP)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2022-03-07
Completion:: 2025-03-30

Conditions

Adenosquamous Carcinoma of the Pancreas

Interventions

DRUG
DIAGNOSTIC_TEST
PROCEDURE

Results Available

NCT04858958 | COMPLETED | PHASE1

90 participants

Study of FURMONERTINIB in Patients With NSCLC Having Exon 20 Insertion Mutation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2020-08-10
Completion:: 2024-12-05

Conditions

NSCLC

Interventions

DRUG

No Results Yet

NCT04856722 | COMPLETED | NA

253 participants

Mini-PNL, RIRS, and ESWL for Treatment of Medium-Sized, High-Density, Non-Lower Pole, Renal Stones

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2021-04-05
Completion:: 2024-06-04

Conditions

Renal Stone
Percutaneous Nephrolithotomy
Retrograde Intrarenal Surgery
Extracorporeal Shockwave Lithotripsy

Interventions

PROCEDURE

No Results Yet

NCT04855552 | ACTIVE_NOT_RECRUITING | NA

22 participants

Telehealth Weight Loss Program for Breast Cancer Survivors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2021-07-19
Completion:: 2027-07-31

Conditions

Cancer Survivors
Cancer of Breast
Body Weight
Overweight and Obesity

Interventions

BEHAVIORAL

No Results Yet

NCT04835493 | ACTIVE_NOT_RECRUITING | NA

320 participants

Evaluating Telementoring for CHW-centered Diabetes Initiatives

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2022-09-01
Completion:: 2025-04-30

Conditions

Diabetes Mellitus, Type 2

Interventions

OTHER

No Results Yet

NCT04825782 | COMPLETED

15391 participants

MiMBa Pregnancy Registry

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-14
Start Date:: 2021-02-22
Completion:: 2025-12-31

Conditions

Malaria in Pregnancy
Pregnancy Related
Congenital Anomaly

No Results Yet

NCT04812366 | RECRUITING | PHASE2

315 participants

Genomic Biomarker-Selected Umbrella Neoadjuvant Study for High Risk Localized Prostate Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2021-09-21
Completion:: 2027-06-01

Conditions

Prostate Cancer

Interventions

DRUG

No Results Yet

NCT04797299 | RECRUITING

526 participants

Prospective Evaluation of Breast-Conserving Surgery Alone in Low-Risk Ductal Carcinoma in Situ (DCIS)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-14
Start Date:: 2022-11-23
Completion:: 2030-11-30

Conditions

DCIS

No Results Yet

NCT04789018 | COMPLETED

118 participants

Enhanced Genetic Awareness and Genetic Evaluation for Men Through Technology, ENGAGEMENT Study

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-14
Start Date:: 2020-01-21
Completion:: 2022-06-02

Conditions

Prostate Carcinoma

Interventions

OTHER

No Results Yet

NCT04786067 | COMPLETED | PHASE4

25 participants

Use of DNA Testing to Help Transition Kidney Transplant Recipients to Belatacept-only Immunosuppression

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2021-07-28
Completion:: 2025-07-10

Conditions

Kidney Transplant Immunosuppression

Interventions

DRUG

Results Available

NCT04776941 | RECRUITING | NA

414 participants

Expressive Writing for the Management of Stress in Cancer Survivors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2020-08-07
Completion:: 2028-12-31

Conditions

Hematopoietic and Lymphoid Cell Neoplasm
Malignant Solid Neoplasm

Interventions

BEHAVIORAL
OTHER

No Results Yet

NCT04775368 | COMPLETED | NA

598 participants

Fibromyalgia Syndrome in France: The Role of Assessment and Management of Sleep Disorders

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2021-04-01
Completion:: 2023-03-07

Conditions

Fibromyalgia

Interventions

OTHER

No Results Yet

NCT04774718 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

42 participants

A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Alectinib in Pediatric Participants With ALK Fusion-Positive Solid or CNS Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2021-09-14
Completion:: 2032-02-28

Conditions

ALK Fusion-positive Solid or CNS Tumors

Interventions

DRUG

No Results Yet

NCT04743141 | RECRUITING | PHASE3

600 participants

Long-term Safety Study of Rimegepant in Pediatric Subjects for the Acute Treatment of Migraine

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2021-04-28
Completion:: 2030-07-31

Conditions

Acute Treatment of Migraine

Interventions

DRUG

No Results Yet

NCT04738825 | ACTIVE_NOT_RECRUITING | NA

526 participants

Promoting HIV Risk Reduction Among People Who Inject Drugs: A Stepped Care Approach Using Contingency Management With PrEP Adherence and Support Services

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2021-10-04
Completion:: 2026-07-31

Conditions

Opioid-use Disorder
HIV Prevention Program

Interventions

BEHAVIORAL

No Results Yet

NCT04736706 | ACTIVE_NOT_RECRUITING | PHASE3

1854 participants

A Study of Pembrolizumab (MK-3475) in Combination With Belzutifan (MK-6482) and Lenvatinib (MK-7902), or Pembrolizumab/Quavonlimab (MK-1308A) in Combination With Lenvatinib, Versus Pembrolizumab and Lenvatinib, for Treatment of Advanced Clear Cell Renal Cell Carcinoma (MK-6482-012)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2021-04-14
Completion:: 2026-02-04

Conditions

Carcinoma, Renal Cell

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT04706026 | ACTIVE_NOT_RECRUITING | NA

18 participants

A Pilot Study of Local Anesthesia for Inguinal Hernia Surgery in Older Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2024-10-23
Completion:: 2026-08-31

Conditions

Inguinal Hernia
Anesthesia, Local

Interventions

OTHER

No Results Yet

NCT04675307 | COMPLETED

50 participants

Multimodal, Task-Aware Movement Assessment and Control: Clinic to the Home

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-14
Start Date:: 2021-02-17
Completion:: 2023-12-01

Conditions

Frailty

No Results Yet

NCT04649242 | RECRUITING | PHASE3

2100 participants

Randomized Study in Children and Adolescents With Migraine: Acute Treatment

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2021-01-15
Completion:: 2029-01-09

Conditions

Pediatric Migraine

Interventions

DRUG

No Results Yet

NCT04591951 | COMPLETED | NA

108 participants

Family Navigation to Improve ADHD Treatment Adherence for Minority Children

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2021-05-14
Completion:: 2026-07-30

Conditions

Attention Deficit Hyperactivity Disorder

Interventions

BEHAVIORAL
OTHER

No Results Yet

NCT04567303 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

177 participants

Study of Zifibancimig in Participants With Neovascular Age-related Macular Degeneration

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2020-10-28
Completion:: 2026-08-25

Conditions

Macular Degeneration

Interventions

DRUG
DEVICE

No Results Yet

NCT04550481 | ACTIVE_NOT_RECRUITING | PHASE2

35 participants

Role of Lisinopril in Preventing the Progression of Non-Alcoholic Fatty Liver Disease, RELIEF-NAFLD Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2021-05-11
Completion:: 2025-08-08

Conditions

Hepatocellular Carcinoma
Nonalcoholic Steatohepatitis

Interventions

PROCEDURE
DRUG
OTHER

Results Available

NCT04537871 | ACTIVE_NOT_RECRUITING

350 participants

Cardiovascular Reserve Evaluation in Survivors of Transplant, CREST Study

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-14
Start Date:: 2020-11-18
Completion:: 2027-05-25

Conditions

Acute Lymphoblastic Leukemia
Acute Myeloid Leukemia
Hematopoietic and Lymphoid Cell Neoplasm
Hodgkin Lymphoma
Myelodysplastic Syndrome
Non-Hodgkin Lymphoma
Plasma Cell Myeloma

Interventions

PROCEDURE
OTHER

No Results Yet

NCT04401020 | TERMINATED | PHASE1

47 participants

First-in-human Single Agent Study of SAR442257 in RRMM and RR-NHL

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2020-07-24
Completion:: 2024-03-02

Conditions

Neoplasm Malignant

Interventions

DRUG

No Results Yet

NCT04381897 | NOT_YET_RECRUITING | PHASE2

10 participants

Use of N-Acetylcysteine in the Treatment of Repetitive and Self-Injurious Behaviors in Cornelia de Lange Syndrome

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2026-11-01
Completion:: 2027-05-01

Conditions

Cornelia de Lange Syndrome

Interventions

DRUG
OTHER

No Results Yet

NCT04367675 | ACTIVE_NOT_RECRUITING | PHASE1

44 participants

INO 5401 Vaccination in BRCA1/2 Mutation Carriers

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2021-04-20
Completion:: 2026-12-31

Conditions

BRCA1/2 Mutation

Interventions

DRUG
DEVICE

No Results Yet

NCT04357080 | COMPLETED

266 participants

Factors Predicting Urethral Stricture Recurrence After Dorsal Onlay Augmented, Buccal Mucosal Graft Urethroplasty

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-14
Start Date:: 2020-07-15
Completion:: 2020-08-15

Conditions

Urethral Stricture

Interventions

PROCEDURE

No Results Yet

NCT04346134 | COMPLETED | NA

72 participants

Mini- Percutaneous Nephrolithotomy Versus Extracorporeal Shock Wave Lithotripsy for High Density Renal Stones

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2020-07-14
Completion:: 2020-12-01

Conditions

Renal Stone
Extracorporeal Shockwave Lithotripsy
Percutaneous Nephrolithotomy

Interventions

PROCEDURE

No Results Yet