Clinical Trials

NCT07245368 | RECRUITING | PHASE1/PHASE2

96 participants

Study of PRA-216 in Healthy Participants and Participants With Mild-to-Moderate Asthma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2025-11-04
Completion:: 2026-10-01

Conditions

Mild to Moderate Asthma

Interventions

DRUG

No Results Yet

NCT07241390 | RECRUITING | PHASE3

7140 participants

A Study of Orforglipron (LY3502970) on Cardiovascular Outcomes in Adults With Atherosclerotic Cardiovascular Disease and/or Chronic Kidney Disease (ATTAIN-Outcomes)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2025-12-01
Completion:: 2031-08-31

Conditions

Atherosclerosis Cardiovascular Disease
Chronic Kidney Disease

Interventions

DRUG

No Results Yet

NCT07230340 | ENROLLING_BY_INVITATION | PHASE4

70 participants

Nonhealing Venous Leg Ulcers Treated With a Standard of Care (SoC) Alone or Standard of Care and Dehydrated Human Placenta Tissue (dHPT) With Crossover

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2026-02-04
Completion:: 2027-08-31

Conditions

Venous Leg Ulcer (VLU)

Interventions

OTHER
PROCEDURE

No Results Yet

NCT07229300 | ENROLLING_BY_INVITATION | NA

1200 participants

AI ECHO INSIGHT RCT for Automated Echo Reporting

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2025-11-01
Completion:: 2026-08-01

Conditions

Echocardiography, Transthoracic
Echocardiographic Software

Interventions

OTHER

No Results Yet

NCT07227987 | RECRUITING | NA

100 participants

Cognitive Rehabilitation for Treatment of Anger in Veterans With TBI and PTSD

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2026-08-04
Completion:: 2028-12-31

Conditions

Traumatic Brain Injury (TBI)
Posttraumatic Stress Disorder (PTSD)

Interventions

OTHER

No Results Yet

NCT07227168 | RECRUITING | PHASE1

200 participants

A Study of STRO-004 in Adults With Refractory/Recurrent Metastatic Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2025-11-07
Completion:: 2027-12-31

Conditions

Head and Neck Squamous Cell Carcinoma HNSCC
Non-Small Cell Lung Cancer NSCLC
Esophageal Cancer
Gastric Cancer
Colorectal Cancer
Pancreatic Ductal Adenocarcinoma (PDAC)
Cervical Cancer
Endometrial Cancer
Urothelial Cancer

Interventions

DRUG

No Results Yet

NCT07226843 | RECRUITING | PHASE1

460 participants

A Study of LY4584180 in Adult Participants With Previously Treated Blood Cancers

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2026-04-17
Completion:: 2027-04-30

Conditions

Lymphoma, Non-Hodgkin's
Lymphoma, Diffuse Large B-Cell
Follicular Lymphoma

Interventions

DRUG

No Results Yet

NCT07223840 | RECRUITING | PHASE2

222 participants

A Study of Brenipatide in Adults Who Quit Smoking Cigarettes and Want to Avoid Relapse

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2025-11-03
Completion:: 2027-02-28

Conditions

Smoking

Interventions

DRUG

No Results Yet

NCT07223814 | RECRUITING | PHASE3

875 participants

Bleximenib in Combination With Standard Induction and Consolidation Therapy Followed by Maintenance for Treatment of Patients With Acute Myeloid Leukemia (AML)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2026-03-01
Completion:: 2030-06-30

Conditions

Acute Myeloid Leukemia

Interventions

DRUG

No Results Yet

NCT07223697 | RECRUITING | PHASE2

120 participants

A Long Term Extension Study to Evaluate the Safety and Efficacy of Afimkibart (RO7790121) in Participants With Atopic Dermatitis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2026-01-08
Completion:: 2033-03-01

Conditions

Atopic Dermatitis

Interventions

DRUG

No Results Yet

NCT07223593 | RECRUITING | PHASE3

1205 participants

Efficacy and Safety of Orforglipron in Participants With Peripheral Artery Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2025-10-31
Completion:: 2028-06-30

Conditions

Peripheral Arterial Disease

Interventions

DRUG

No Results Yet

NCT07223385 | RECRUITING | PHASE2

80 participants

High Cardiovascular Risk Intervention With Cardio-Oncology Consultation for Prostate Cancer Following Androgen Receptor Pathway Inhibitor (ARPI) Therapy (Heart-Safe)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2026-08-01
Completion:: 2030-08-31

Conditions

Prostate Cancer (Diagnosis)
Prostate Cancer Stage IV
CV Risk

Interventions

OTHER

No Results Yet

NCT07223151 | RECRUITING | NA

63 participants

A Sensory Strategy to Cut Sugary Beverages in African/American and Latine Adolescents

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2025-07-25
Completion:: 2027-06-30

Conditions

Obesity, Adolescent
Dietary Sugars
Taste Perception
Insulin Resistance
Feeding Behavior

Interventions

BEHAVIORAL

No Results Yet

NCT07222852 | RECRUITING | PHASE3

60 participants

Cardiovascular Protection After Preeclampsia With Enalapril

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2026-01-01
Completion:: 2027-10-15

Conditions

Preeclampsia
Hypertensive Disorder of Pregnancy
Hypertension
Gestational Hypertension
Gestational Hypertension After Childbirth

Interventions

DRUG
OTHER

No Results Yet

NCT07222332 | RECRUITING | PHASE3

300 participants

A Study of Baricitinib (LY3009104) to Preserve Beta Cell Function in Children and Adults Newly Diagnosed With Type 1 Diabetes (BARICADE-PRESERVE)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2026-02-05
Completion:: 2028-07-31

Conditions

Diabetes Mellitus, Type 1

Interventions

DRUG

No Results Yet

NCT07222306 | ENROLLING_BY_INVITATION

100 participants

Cannabis, Neuroinflammation, and Suicidal Ideation: A Supplemental Brain Imaging Study

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-06
Start Date:: 2026-01-01
Completion:: 2030-08-31

Conditions

PTSD
Suicidal Thoughts and Behaviors
PTSD Symptoms
Depressive Symptoms

Interventions

DRUG

No Results Yet

NCT07222137 | RECRUITING | PHASE3

150 participants

A Study of Baricitinib (LY3009104) for the Delay of Stage 3 Type 1 Diabetes in At-Risk Children and Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2026-01-12
Completion:: 2031-07-31

Conditions

Diabetes Mellitus, Type 1

Interventions

DRUG

No Results Yet

NCT07220642 | ACTIVE_NOT_RECRUITING | PHASE3

300 participants

Weight Loss in People Living With Overweight or Obesity Following Treatment With Cagrilintide

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2025-11-05
Completion:: 2027-05-11

Conditions

Obesity
Overweight

Interventions

DRUG

No Results Yet

NCT07219966 | RECRUITING | PHASE3

1100 participants

A Study of Brenipatide in Participants With Moderate-to-Severe Alcohol Use Disorder

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2025-10-15
Completion:: 2028-04-30

Conditions

Alcohol Use Disorder

Interventions

DRUG

No Results Yet

NCT07219953 | RECRUITING | PHASE3

1100 participants

A Study of Brenipatide in Participants With Alcohol Use Disorder

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2025-10-16
Completion:: 2028-04-30

Conditions

Alcohol Use Disorder

Interventions

DRUG

No Results Yet

NCT07218341 | RECRUITING | PHASE4

150 participants

A Study of Pirtobrutinib (LY3527727) in Participants With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2026-03-09
Completion:: 2030-05-31

Conditions

Chronic Lymphocytic Leukemia
Lymphoma, Small Lymphocytic

Interventions

DRUG

No Results Yet

NCT07216716 | RECRUITING | NA

15 participants

Evaluating the Effectiveness of the Health App Recommendation Tool

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2025-12-05
Completion:: 2026-09-30

Conditions

Alzheimers Disease Related Dementias

Interventions

OTHER

No Results Yet

NCT07215468 | ACTIVE_NOT_RECRUITING | PHASE2

88 participants

HIV-1 Virologic Suppression With TMB-365 and TMB-380 Antibodies Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2025-12-16
Completion:: 2027-05-31

Conditions

HIV -1 Infection

Interventions

DRUG

No Results Yet

NCT07214779 | RECRUITING | PHASE3

466 participants

Study to Evaluate INCB123667 Versus Investigator's Choice of Chemotherapy in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2025-12-09
Completion:: 2028-11-15

Conditions

Ovarian Cancer

Interventions

DRUG

No Results Yet

NCT07213973 | RECRUITING | PHASE2

40 participants

Pharmacokinetics, Safety, and Efficacy of Povorcitinib in Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2026-02-02
Completion:: 2028-03-25

Conditions

Hidradenitis Suppurativa (HS)

Interventions

DRUG

No Results Yet

NCT07213804 | RECRUITING | PHASE3

1630 participants

A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Parts B and C) Ovarian Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2025-10-22
Completion:: 2028-11-30

Conditions

Ovarian Neoplasms
Fallopian Tube Neoplasms
Peritoneal Neoplasms
Neoplasm Metastasis

Interventions

DRUG

No Results Yet

NCT07213791 | RECRUITING | PHASE1

241 participants

A Study of LY4337713 in Participants With FAP-Positive Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2025-10-22
Completion:: 2028-07-31

Conditions

Ovarian Neoplasms
Breast Neoplasms
Pancreatic Intraductal Neoplasms
Colorectal Neoplasms
Esophageal Neoplasms
Stomach Neoplasms
Cholangiocarcinoma

Interventions

DRUG

No Results Yet

NCT07207876 | RECRUITING

110 participants

Study of Ceftriaxone and Benzathine Penicillin G During Pregnancy

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-06
Start Date:: 2026-02-16
Completion:: 2027-01-15

Conditions

Pregnancy

Interventions

DRUG

No Results Yet

NCT07204951 | COMPLETED | NA

64 participants

Clinical Safety and Efficacy Study of Water Flosser in Enhancing Oral Health Among Healthy Adults Having Plaque-induced Gingivitis and Dental Plaque Accumulation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2025-11-13
Completion:: 2026-02-14

Conditions

Plaque Induced Gingivitis

Interventions

DEVICE
OTHER

No Results Yet

NCT07202884 | RECRUITING | PHASE3

1000 participants

A Study of Orforglipron in Female Participants With Stress Urinary Incontinence Who Have Obesity or Overweight

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2025-09-30
Completion:: 2028-03-31

Conditions

Urinary Incontinence,Stress

Interventions

DRUG

No Results Yet

NCT07200375 | RECRUITING

300 participants

An Observational Study of Glofitamab in Chinese Adult Participants With 2L Diffuse Large B-Cell Lymphoma

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-06
Start Date:: 2025-09-29
Completion:: 2029-09-29

Conditions

Diffuse Large B-Cell Lymphoma

Interventions

DRUG

No Results Yet

NCT07199738 | RECRUITING

144 participants

A Multi-Center Study Assessing the Safety and Efficacy of the LEGION Medial Stabilized (MS) Insert in Patients Undergoing a Total Knee Arthroplasty (TKA)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-06
Start Date:: 2025-09-25
Completion:: 2036-12-31

Conditions

Inflammatory Arthritis
Primary Total Knee Arthroplasty Due to Degenerative Joint Disease (Primary Diagnosis of Osteoarthritis)
Post-traumatic Arthritis

Interventions

DEVICE

No Results Yet

NCT07195916 | RECRUITING | PHASE1

280 participants

A Study to Evaluate INCA036873 in Participants With Advanced Solid Tumors and Hematological Malignancies

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2026-01-08
Completion:: 2028-08-18

Conditions

Solid Tumors
Hematologic Malignancies

Interventions

DRUG

No Results Yet

NCT07188896 | RECRUITING | PHASE2

120 participants

A Randomized Trial of Fianlimab and Cemiplimab +/- Ipilimumab or Ipilimumab Plus Nivolumab in First-line Advanced Renal Cell Carcinoma (RCC)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2026-04-29
Completion:: 2029-11-30

Conditions

Advanced Renal Cell Carcinoma (aRCC)
Metastatic Renal Cell Carcinoma ( mRCC)
Clear Cell Renal Cell Carcinoma (ccRCC)

Interventions

DRUG

No Results Yet

NCT07186101 | RECRUITING | PHASE2

252 participants

LY4268989 (MORF-057) Co-Administered With Mirikizumab in Adults With Moderately to Severely Active Ulcerative Colitis:

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2025-11-10
Completion:: 2027-05-31

Conditions

Ulcerative Colitis

Interventions

DRUG

No Results Yet

NCT07178990 | RECRUITING | NA

50 participants

Mobile Platform for Optimizing Wellness and Engagement in Recovery

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2025-12-08
Completion:: 2027-07-01

Conditions

Opioid Agonist Treatment
Alcohol Use Disorder
Opioid Use Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT07174336 | RECRUITING | PHASE3

800 participants

A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2025-12-22
Completion:: 2029-05-31

Conditions

Breast Neoplasms
Neoplasm Metastasis

Interventions

DRUG

No Results Yet

NCT07174310 | RECRUITING | PHASE3

900 participants

A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2025-11-24
Completion:: 2029-06-30

Conditions

Parkinson's Disease

Interventions

DRUG

No Results Yet

NCT07170150 | RECRUITING | PHASE3

800 participants

A Clinical Trial of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2025-11-12
Completion:: 2028-06-07

Conditions

Alzheimers Disease

Interventions

DRUG
OTHER

No Results Yet

NCT07169851 | RECRUITING | PHASE2

204 participants

A Study to Evaluate LY3537021 for the Treatment of Nausea and Vomiting Caused by Chemotherapy in Adults With Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2025-11-28
Completion:: 2026-12-31

Conditions

Nausea
Vomiting
Drug-Related Side Effects and Adverse Reactions
Neoplasms

Interventions

DRUG

No Results Yet