Clinical Trials

NCT07222332 | RECRUITING | PHASE3

300 participants

A Study of Baricitinib (LY3009104) to Preserve Beta Cell Function in Children and Adults Newly Diagnosed With Type 1 Diabetes (BARICADE-PRESERVE)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2026-02-05
Completion:: 2028-07-31

Conditions

Diabetes Mellitus, Type 1

Interventions

DRUG

No Results Yet

NCT07222306 | ENROLLING_BY_INVITATION

100 participants

Cannabis, Neuroinflammation, and Suicidal Ideation: A Supplemental Brain Imaging Study

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-06
Start Date:: 2026-01-01
Completion:: 2030-08-31

Conditions

PTSD
Suicidal Thoughts and Behaviors
PTSD Symptoms
Depressive Symptoms

Interventions

DRUG

No Results Yet

NCT07222137 | RECRUITING | PHASE3

150 participants

A Study of Baricitinib (LY3009104) for the Delay of Stage 3 Type 1 Diabetes in At-Risk Children and Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2026-01-12
Completion:: 2031-07-31

Conditions

Diabetes Mellitus, Type 1

Interventions

DRUG

No Results Yet

NCT07220642 | ACTIVE_NOT_RECRUITING | PHASE3

300 participants

Weight Loss in People Living With Overweight or Obesity Following Treatment With Cagrilintide

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2025-11-05
Completion:: 2027-05-11

Conditions

Obesity
Overweight

Interventions

DRUG

No Results Yet

NCT07219966 | RECRUITING | PHASE3

1100 participants

A Study of Brenipatide in Participants With Moderate-to-Severe Alcohol Use Disorder

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2025-10-15
Completion:: 2028-04-30

Conditions

Alcohol Use Disorder

Interventions

DRUG

No Results Yet

NCT07219953 | RECRUITING | PHASE3

1100 participants

A Study of Brenipatide in Participants With Alcohol Use Disorder

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2025-10-16
Completion:: 2028-04-30

Conditions

Alcohol Use Disorder

Interventions

DRUG

No Results Yet

NCT07218341 | RECRUITING | PHASE4

150 participants

A Study of Pirtobrutinib (LY3527727) in Participants With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2026-03-09
Completion:: 2030-05-31

Conditions

Chronic Lymphocytic Leukemia
Lymphoma, Small Lymphocytic

Interventions

DRUG

No Results Yet

NCT07216716 | RECRUITING | NA

15 participants

Evaluating the Effectiveness of the Health App Recommendation Tool

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2025-12-05
Completion:: 2026-09-30

Conditions

Alzheimers Disease Related Dementias

Interventions

OTHER

No Results Yet

NCT07215468 | ACTIVE_NOT_RECRUITING | PHASE2

88 participants

HIV-1 Virologic Suppression With TMB-365 and TMB-380 Antibodies Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2025-12-16
Completion:: 2027-05-31

Conditions

HIV -1 Infection

Interventions

DRUG

No Results Yet

NCT07214779 | RECRUITING | PHASE3

466 participants

Study to Evaluate INCB123667 Versus Investigator's Choice of Chemotherapy in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2025-12-09
Completion:: 2028-11-15

Conditions

Ovarian Cancer

Interventions

DRUG

No Results Yet

NCT07213973 | RECRUITING | PHASE2

40 participants

Pharmacokinetics, Safety, and Efficacy of Povorcitinib in Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2026-02-02
Completion:: 2028-03-25

Conditions

Hidradenitis Suppurativa (HS)

Interventions

DRUG

No Results Yet

NCT07213804 | RECRUITING | PHASE3

1630 participants

A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Parts B and C) Ovarian Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2025-10-22
Completion:: 2028-11-30

Conditions

Ovarian Neoplasms
Fallopian Tube Neoplasms
Peritoneal Neoplasms
Neoplasm Metastasis

Interventions

DRUG

No Results Yet

NCT07213791 | RECRUITING | PHASE1

241 participants

A Study of LY4337713 in Participants With FAP-Positive Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2025-10-22
Completion:: 2028-07-31

Conditions

Ovarian Neoplasms
Breast Neoplasms
Pancreatic Intraductal Neoplasms
Colorectal Neoplasms
Esophageal Neoplasms
Stomach Neoplasms
Cholangiocarcinoma

Interventions

DRUG

No Results Yet

NCT07207876 | RECRUITING

110 participants

Study of Ceftriaxone and Benzathine Penicillin G During Pregnancy

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-06
Start Date:: 2026-02-16
Completion:: 2027-01-15

Conditions

Pregnancy

Interventions

DRUG

No Results Yet

NCT07204951 | COMPLETED | NA

64 participants

Clinical Safety and Efficacy Study of Water Flosser in Enhancing Oral Health Among Healthy Adults Having Plaque-induced Gingivitis and Dental Plaque Accumulation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2025-11-13
Completion:: 2026-02-14

Conditions

Plaque Induced Gingivitis

Interventions

DEVICE
OTHER

No Results Yet

NCT07202884 | RECRUITING | PHASE3

1000 participants

A Study of Orforglipron in Female Participants With Stress Urinary Incontinence Who Have Obesity or Overweight

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2025-09-30
Completion:: 2028-03-31

Conditions

Urinary Incontinence,Stress

Interventions

DRUG

No Results Yet

NCT07200375 | RECRUITING

300 participants

An Observational Study of Glofitamab in Chinese Adult Participants With 2L Diffuse Large B-Cell Lymphoma

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-06
Start Date:: 2025-09-29
Completion:: 2029-09-29

Conditions

Diffuse Large B-Cell Lymphoma

Interventions

DRUG

No Results Yet

NCT07199738 | RECRUITING

144 participants

A Multi-Center Study Assessing the Safety and Efficacy of the LEGION Medial Stabilized (MS) Insert in Patients Undergoing a Total Knee Arthroplasty (TKA)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-06
Start Date:: 2025-09-25
Completion:: 2036-12-31

Conditions

Inflammatory Arthritis
Primary Total Knee Arthroplasty Due to Degenerative Joint Disease (Primary Diagnosis of Osteoarthritis)
Post-traumatic Arthritis

Interventions

DEVICE

No Results Yet

NCT07195916 | RECRUITING | PHASE1

280 participants

A Study to Evaluate INCA036873 in Participants With Advanced Solid Tumors and Hematological Malignancies

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2026-01-08
Completion:: 2028-08-18

Conditions

Solid Tumors
Hematologic Malignancies

Interventions

DRUG

No Results Yet

NCT07188896 | RECRUITING | PHASE2

120 participants

A Randomized Trial of Fianlimab and Cemiplimab +/- Ipilimumab or Ipilimumab Plus Nivolumab in First-line Advanced Renal Cell Carcinoma (RCC)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2026-04-29
Completion:: 2029-11-30

Conditions

Advanced Renal Cell Carcinoma (aRCC)
Metastatic Renal Cell Carcinoma ( mRCC)
Clear Cell Renal Cell Carcinoma (ccRCC)

Interventions

DRUG

No Results Yet

NCT07186101 | RECRUITING | PHASE2

252 participants

LY4268989 (MORF-057) Co-Administered With Mirikizumab in Adults With Moderately to Severely Active Ulcerative Colitis:

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2025-11-10
Completion:: 2027-05-31

Conditions

Ulcerative Colitis

Interventions

DRUG

No Results Yet

NCT07178990 | RECRUITING | NA

50 participants

Mobile Platform for Optimizing Wellness and Engagement in Recovery

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2025-12-08
Completion:: 2027-07-01

Conditions

Opioid Agonist Treatment
Alcohol Use Disorder
Opioid Use Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT07174336 | RECRUITING | PHASE3

800 participants

A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2025-12-22
Completion:: 2029-05-31

Conditions

Breast Neoplasms
Neoplasm Metastasis

Interventions

DRUG

No Results Yet

NCT07174310 | RECRUITING | PHASE3

900 participants

A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2025-11-24
Completion:: 2029-06-30

Conditions

Parkinson's Disease

Interventions

DRUG

No Results Yet

NCT07170150 | RECRUITING | PHASE3

800 participants

A Clinical Trial of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2025-11-12
Completion:: 2028-06-07

Conditions

Alzheimers Disease

Interventions

DRUG
OTHER

No Results Yet

NCT07169851 | RECRUITING | PHASE2

204 participants

A Study to Evaluate LY3537021 for the Treatment of Nausea and Vomiting Caused by Chemotherapy in Adults With Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2025-11-28
Completion:: 2026-12-31

Conditions

Nausea
Vomiting
Drug-Related Side Effects and Adverse Reactions
Neoplasms

Interventions

DRUG

No Results Yet

NCT07169578 | RECRUITING | PHASE3

800 participants

A Study of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2025-09-17
Completion:: 2028-06-07

Conditions

Alzheimers Disease

Interventions

DRUG
OTHER

No Results Yet

NCT07168668 | NOT_YET_RECRUITING | PHASE2

90 participants

Partial Immune-boost TACE in unrEseCTable HCC Patients Under Systemic Treatment

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2026-09-15
Completion:: 2029-08-14

Conditions

HCC
Tace
Immunotherapy

Interventions

PROCEDURE
DRUG

No Results Yet

NCT07167004 | RECRUITING | NA

216 participants

The GRoceries Aimed at Increasing Nutrition Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2025-10-14
Completion:: 2027-02-16

Conditions

Type 2 Diabetes
Type II Diabetes Mellitus
Type II Diabetes
Pre-diabetes
Pre-diabetic
Pre-diabetic State
Type 2 Diabetes Mellitus (T2DM)
Type 2 Diabetes Mellitus
Type 2 Diabetes (T2DM)

Interventions

BEHAVIORAL

No Results Yet

NCT07165756 | TERMINATED

34 participants

"Mon Parcours de Vie" Localized Breast Cancer: Announcement, Support, Information on the Disease and Treatments. Pilot Study to Assess the Value of Written Information Documents.

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-06
Start Date:: 2025-09-09
Completion:: 2026-04-02

Conditions

Localized Breast Cancer

No Results Yet

NCT07165028 | RECRUITING | PHASE3

4500 participants

A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2025-10-15
Completion:: 2030-08-31

Conditions

Metabolic Dysfunction-Associated Steatotic Liver Disease

Interventions

DRUG

No Results Yet

NCT07162623 | COMPLETED | NA

62 participants

Clinical Study to Assess Safety, Efficacy and In-Use Tolerability of Oziva Bioactive Gluta Fizzy Effervescent Tablets on Subjects With Facial Dark Spots Such as Pimple Marks, Sunspots, Age Spots and Uneven Skin Tone

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2025-09-02
Completion:: 2026-04-15

Conditions

Hyperpigmentation

Interventions

OTHER

No Results Yet

NCT07161999 | RECRUITING | PHASE2/PHASE3

120 participants

Study of COYA 302 for the Treatment of ALS

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2025-10-01
Completion:: 2027-01-31

Conditions

Amyotrophic Lateral Sclerosis (ALS)

Interventions

DRUG

No Results Yet

NCT07159204 | ACTIVE_NOT_RECRUITING | PHASE2

61 participants

Polymeric Micellar Paclitaxel-Based Combination Therapy for Advanced Biliary Tract Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2024-08-07
Completion:: 2026-08-12

Conditions

Biliary Tract Cancer (BTC)

Interventions

DRUG

No Results Yet

NCT07156474 | ACTIVE_NOT_RECRUITING

44504 participants

Impact of Intraoperative Blood Pressure Components on Postoperative AKI: A Phenotype-Stratified Analysis

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-06
Start Date:: 2025-09-09
Completion:: 2026-12-31

Conditions

Postoperative Acute Kidney Injury
Intraoperative Hypotension

No Results Yet

NCT07153471 | RECRUITING | PHASE3

800 participants

A Study of Orforglipron (LY3502970) in Participants With Obesity or Overweight and Osteoarthritis (OA) of the Knee

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2025-09-15
Completion:: 2028-04-30

Conditions

Osteoarthritis

Interventions

DRUG

No Results Yet

NCT07144228 | RECRUITING

300 participants

Validation of a Platelet Proteomic Assay for Diagnosing and Monitoring Prostate Cancer

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-06
Start Date:: 2026-03-11
Completion:: 2026-09-30

Conditions

Prostate Cancer (Diagnosis)

Interventions

DEVICE

No Results Yet

NCT07144137 | RECRUITING

75 participants

A Non-Interventional Study Observing Short-Term Progression in Geographic Atrophy (GA)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-06
Start Date:: 2025-07-30
Completion:: 2027-03-31

Conditions

Geographic Atrophy Secondary to Age-related Macular Degeneration

No Results Yet

NCT07142655 | COMPLETED

1500 participants

An Observational Study to Learn More About the Safety of Rivaroxaban in Participants With Peripheral Arterial Disease Who Had Surgery to Improve Blood Flow to Their Legs

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-06
Start Date:: 2025-08-12
Completion:: 2026-03-09

Conditions

Peripheral Arterial Disease (PAD)

No Results Yet

NCT07136922 | RECRUITING | PHASE1

20 participants

First in Human Safety and Ease of Use Assessment of 400mg Progesterone Callavid in Women With Luteal Phase Insufficiency

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2026-04-20
Completion:: 2026-08-31

Conditions

Luteal Phase Insuffiency
Progesterone Delivery

Interventions

COMBINATION_PRODUCT
DRUG

No Results Yet