Clinical Trials

NCT06162728 | COMPLETED | PHASE1/PHASE2

87 participants

Dose Escalation Trial Of Safety, Pharmacokinetic/Pharmacodynamic And Preliminary Clinical Activity of Briquilimab In Adult Patients With Chronic Spontaneous Urticaria (CSU)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-11-29

Completion:

2026-07-08

Conditions

• Chronic Spontaneous Urticaria

Interventions

• DRUG
• OTHER

No Results Yet

NCT06157671 | ENROLLING_BY_INVITATION

1000 participants

The LINFU® U.S. Registry for the Detection of Asymptomatic Pancreatic Ductal Adenocarcinoma

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2024-01-31

Completion:

2030-01-01

Conditions

• Pancreatic Adenocarcinoma
• Pancreatic Intraepithelial Neoplasia

No Results Yet

NCT06150729 | COMPLETED

107 participants

Study of Intramuscular Injections of OnabotulinumtoxinA to Assess Change in Disease Activity in Pediatric Participants With Spasticity Associated With Cerebral Palsy

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2023-09-08

Completion:

2025-05-30

Conditions

• Spasticity

No Results Yet

NCT06147843 | RECRUITING | NA

1000 participants

French-German Cohort Study to Determine Factors Associated With Weight Loss in Amyotrophic Lateral Sclerosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-09-17

Completion:

2027-09-30

Conditions

• Amyotrophic Lateral Sclerosis

Interventions

• OTHER

No Results Yet

NCT06145633 | RECRUITING | PHASE2

15 participants

Vorinostat and 177Lu-PSMA-617 for the Treatment of PSMA-Low Metastatic Castration-Resistant Prostate Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-09-18

Completion:

2026-12-30

Conditions

• Castration-Resistant Prostate Carcinoma
• Metastatic Prostate Adenocarcinoma
• Stage IVB Prostate Cancer AJCC v8

Interventions

• PROCEDURE
• OTHER
• DRUG

No Results Yet

NCT06144749 | COMPLETED | PHASE2

13 participants

A Safety, Efficacy, and Pharmacokinetic (PK) Study of HBI-002, an Oral Carbon Monoxide (CO) Therapeutic, in Subjects With Sickle Cell Disease (SCD)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2025-02-15

Completion:

2026-06-30

Conditions

• Anemia, Sickle Cell

Interventions

• DRUG

No Results Yet

NCT06143956 | RECRUITING | PHASE2

1481 participants

A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in Adult Participants With Obesity or Overweight

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-11-17

Completion:

2027-09-30

Conditions

• Obesity
• Overweight

Interventions

• DRUG

No Results Yet

NCT06131554 | COMPLETED | PHASE3

1480 participants

A Clinical Trial to Evaluate the Immunogenicity and Safety of Group ACYW135 Meningococcal Conjugate Vaccine (CRM197) in Adults Aged 18 to 55 Years

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-03-20

Completion:

2024-07-12

Conditions

• Meningococcal Meningitis

Interventions

• BIOLOGICAL

No Results Yet

NCT06129864 | RECRUITING | PHASE3

1145 participants

A Global Study of Volrustomig (MEDI5752) for Participants With Unresected Locally Advanced Head and Neck Squamous Cell Carcinoma Following Definitive Concurrent Chemoradiotherapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-12-14

Completion:

2030-04-17

Conditions

• Locally Advanced Head and Neck Squamous Cell Carcinoma

Interventions

• DRUG

No Results Yet

NCT06129747 | RECRUITING | PHASE2

55 participants

Repeat Breast Conserving Surgery Followed by Daily Partial Breast Irradiation in Ipsilateral Breast

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-11-30

Completion:

2029-08-09

Conditions

• Breast Cancer
• Tumor, Breast

Interventions

• RADIATION

No Results Yet

NCT06113939 | NOT_YET_RECRUITING | PHASE4

60 participants

Prevention of Infection of the Respiratory Tract Through Application of Non-Invasive Methods of Secretion Suctioning

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2026-09-15

Completion:

2028-12-30

Conditions

• Intubation Complication
• Stroke, Ischemic
• Stroke Hemorrhagic
• Head Trauma
• Cardiac Arrest
• Ventilator Associated Pneumonia
• Airway Clearance Impairment

Interventions

• DEVICE
• DRUG

No Results Yet

NCT06112743 | ACTIVE_NOT_RECRUITING | PHASE4

63 participants

A Study to Evaluate Mavacamten Impact on Myocardial Structure in Participants With Symptomatic Obstructive Hypertrophic Cardiomyopathy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-01-24

Completion:

2026-07-16

Conditions

• Cardiomyopathy, Hypertrophic

Interventions

• DRUG

No Results Yet

NCT06106373 | COMPLETED | NA

20 participants

iotaSOFT Pediatric Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2022-05-17

Completion:

2024-10-24

Conditions

• Hearing Loss, Sensorineural
• Hearing Loss, Bilateral
• Hearing Loss, Unilateral

Interventions

• DEVICE

Results Available

NCT06099288 | RECRUITING | NA

257 participants

Strong Families Start at Home/Familias Fuertes Comienzan en Casa

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-01-01

Completion:

2027-11-01

Conditions

• Metabolic Syndrome, Protection Against
• Diet, Healthy

Interventions

• BEHAVIORAL

No Results Yet

NCT06092476 | ACTIVE_NOT_RECRUITING | NA

18 participants

Trial to Evaluate Efficacy+Safety of Revita DMR Treatment Paradigm 1 and Retreatment in Type 2 Diabetes Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-08-09

Completion:

2027-03-01

Conditions

• Diabetes Mellitus, Type 2

Interventions

• DEVICE
• OTHER

No Results Yet

NCT06091865 | RECRUITING | PHASE3

904 participants

A Study to Compare How Well Odronextamab Combined With Chemotherapy Works and How Safe it is Against Rituximab Combined With Chemotherapy, in Adult Patients With Previously Untreated Diffuse Large B-cell Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-12-13

Completion:

2028-03-30

Conditions

• Diffuse Large B-cell Lymphoma (DLBCL)

Interventions

• DRUG

No Results Yet

NCT06090864 | RECRUITING | PHASE1/PHASE2

31 participants

ATLCAR.CD30.CCR4 for CD30+ HL ATLCAR.CD30.CCR4 Cells

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-04-25

Completion:

2028-08-03

Conditions

• Hodgkin Lymphoma
• Relapse
• Refractory

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT06085781 | RECRUITING | NA

60 participants

A Study of Head and Neck MRI and Tumor Microenvironment Biomarkers

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-01-29

Completion:

2027-01-15

Conditions

• Squamous Cell Carcinoma of Head and Neck

Interventions

• OTHER

No Results Yet

NCT06069141 | RECRUITING | NA

688 participants

Comparisons of Treatment Responses of Early Syphilis to Benzathine Penicillin G With or Without Doxycycline

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-01-01

Completion:

2027-12-31

Conditions

• Early Syphilis, Latent, Serological Relapse After Treatment

Interventions

• DRUG

No Results Yet

NCT06066528 | COMPLETED | PHASE3

755 participants

A Study to Test Whether Survodutide (BI 456906) Helps People Living With Overweight or Obesity Who Also Have Diabetes to Lose Weight

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-11-27

Completion:

2025-12-12

Conditions

• Obesity
• Diabetes Mellitus, Type 2

Interventions

• COMBINATION_PRODUCT

No Results Yet

NCT06061614 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1

15 participants

Safety and Efficacy Study of NGGT002 in PKU Adult Subjects

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-03-30

Completion:

2028-12-30

Conditions

• Phenylketonurias

Interventions

• GENETIC

No Results Yet

NCT06060743 | COMPLETED | NA

88 participants

Examining the Effect of Mobile Application on Insulin Use Perception and Self-Management

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-01-01

Completion:

2024-05-01

Conditions

• Type 2 Diabetes Treated With Insulin

Interventions

• OTHER

No Results Yet

NCT06056895 | ACTIVE_NOT_RECRUITING | PHASE2

12 participants

Triple Immune Checkpoint Inhibition for Advanced or Metastatic PD-(L)1 Refractory Merkel Cell Carcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-11-08

Completion:

2027-01-31

Conditions

• Unresectable Clinical Stage III Merkel Cell Carcinoma AJCC v8
• Clinical Stage IV Merkel Cell Carcinoma AJCC v8
• Merkel Cell Carcinoma

Interventions

• PROCEDURE
• BIOLOGICAL
• DRUG

No Results Yet

NCT06056297 | RECRUITING | PHASE3

176 participants

A Study of Mavorixafor in Participants With Congenital and Acquired Primary Autoimmune and Idiopathic Chronic Neutropenic Disorders Who Are Experiencing Recurrent and/or Serious Infections

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-06-06

Completion:

2027-09-30

Conditions

• Neutropenia

Interventions

• DRUG

No Results Yet

NCT06055920 | ACTIVE_NOT_RECRUITING | NA

1200 participants

The PEERLESS II Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-11-17

Completion:

2026-08-31

Conditions

• Pulmonary Embolism

Interventions

• DEVICE
• DRUG

No Results Yet

NCT06049212 | ACTIVE_NOT_RECRUITING | PHASE1

30 participants

Sacituzumab Tirumotecan (MK-2870) as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors (MK-2870-008)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-10-26

Completion:

2026-12-31

Conditions

• Non-small Cell Lung Cancer
• Solid Tumors
• Programmed Cell Death-1 (PD1, PD-1)
• Programmed Cell Death 1 Ligand 1(PDL1, PD-L1)
• Programmed Cell Death 1 Ligand 2 (PDL2, PD-L2)

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT06041581 | ENROLLING_BY_INVITATION | NA

200 participants

SHADES Mechanistic Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-04-25

Completion:

2027-07-31

Conditions

• Insomnia
• Insomnia Chronic
• Insomnia, Primary
• Sleep Disturbance
• Sleep Disorder
• Cardiovascular Diseases
• Heart Diseases
• Coronary Artery Disease
• Stroke
• Autonomic Dysfunction
• Systemic Inflammatory Response
• Metabolic Disease

Interventions

• BEHAVIORAL
• OTHER

No Results Yet

NCT06030128 | COMPLETED | NA

150 participants

Core Stabilization Exercise Therapy in Chronic Lower Back Back Management in Community Dwelling Older Adults

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-09-15

Completion:

2025-05-01

Conditions

• Chronic Low-back Pain
• Older Adults
• Core Stabilization Exercise Therapy

Interventions

• BEHAVIORAL

No Results Yet

NCT05995821 | RECRUITING

1250 participants

Immunobiology Blood and Tissue Collection of Upper Aerodigestive Malignancies

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2016-08-25

Completion:

2028-08-25

Conditions

• Head and Neck Cancer
• Lung Cancer
• Gastrointestinal Cancer

Interventions

• OTHER

No Results Yet

NCT05990465 | RECRUITING | PHASE1

12 participants

LV20.19 CAR T-Cells in Combination With Pirtobrutinib for Relapsed, Refractory B-cell Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2025-02-06

Completion:

2028-07-31

Conditions

• Non Hodgkin Lymphoma
• Diffuse Large B Cell Lymphoma
• Follicular Lymphoma
• Marginal Zone Lymphoma
• Mantle Cell Lymphoma
• Burkitt Lymphoma

Interventions

• DRUG

No Results Yet

NCT05988385 | RECRUITING | NA

200 participants

The Effects of Successful OSA Treatment on Memory and AD Biomarkers in Older Adults Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-08-29

Completion:

2027-06-30

Conditions

• Obstructive Sleep Apnea
• Cognitive Decline

Interventions

• DEVICE

No Results Yet

NCT05984238 | COMPLETED | NA

33 participants

A Trial to Evaluate Safety, Feasibility and Efficacy of Endoscopic Duodenal PEF Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-08-03

Completion:

2025-03-21

Conditions

• Diabetes Mellitus, Type 2

Interventions

• DEVICE
• DRUG
• OTHER

No Results Yet

NCT05976763 | RECRUITING | PHASE3

421 participants

Testing Continuous Versus Intermittent Treatment With the Study Drug Zanubrutinib for Older Patients With Previously Untreated Mantle Cell Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-10-20

Completion:

2038-08-31

Conditions

• Mantle Cell Lymphoma

Interventions

• PROCEDURE
• OTHER
• DRUG
• BIOLOGICAL

No Results Yet

NCT05958342 | RECRUITING | PHASE2

1050 participants

CAlcium and VAsopressin Following Injury Early Resuscitation (CAVALIER) Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-06-30

Completion:

2027-03-31

Conditions

• Trauma
• Hemorrhage

Interventions

• DRUG

No Results Yet

NCT05952856 | COMPLETED | PHASE3

2912 participants

A Study of Enlicitide Decanoate (MK-0616 Oral PCSK9 Inhibitor) in Adults With Hypercholesterolemia (MK-0616-013) CORALreef Lipids

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-08-10

Completion:

2025-07-28

Conditions

• Hypercholesterolemia
• Familial Hypercholesterolemia

Interventions

• DRUG

Results Available

NCT05952024 | RECRUITING | PHASE2

80 participants

Study of Acalabrutinib and Rituximab in Untreated Elderly and/or Frail Patients With DLBCL

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-07-16

Completion:

2029-04-22

Conditions

• Diffuse Large B-Cell Lymphoma

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT05944224 | RECRUITING | PHASE1/PHASE2

63 participants

A Study to Efficacy and Safety of SPH4336 Monotherapy or in Combination With Cadonilimab in Patients With Advanced Solid Tumors.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-10-17

Completion:

2026-12-31

Conditions

• Advanced Solid Tumors

Interventions

• DRUG

No Results Yet

NCT05942313 | RECRUITING

100 participants

Predicting and Preventing Adverse Maternal and Child Outcomes of Opioid Use Disorder in Pregnancy

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2023-08-28

Completion:

2026-12-01

Conditions

• Opioid Use Disorder
• Pregnancy Related

Interventions

• DRUG

No Results Yet

NCT05908240 | ACTIVE_NOT_RECRUITING | NA

520 participants

Prevention of Cardiovascular Disease and Mortality in Patients With Psoriasis or Psoriatic Arthritis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-06-15

Completion:

2026-09-30

Conditions

• Psoriasis
• Psoriatic Arthritis
• Psoriatic Conditions
• Cardiovascular Diseases

Interventions

• OTHER

No Results Yet

NCT05900427 | TERMINATED | PHASE4

78 participants

Effects on Postoperative Pain of Liposomal Bupivacaine in Interscalene Blocks for Total Shoulder Arthroplasty Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-10-23

Completion:

2025-10-05

Conditions

• Total Shoulder Arthroplasty
• Reverse Total Shoulder Arthroplasty

Interventions

• DRUG

Results Available