Clinical Trials

NCT06120283 | RECRUITING | PHASE1

399 participants

BGB-43395 Alone or as Part of Combination Therapies in Participants With Breast Cancer and Other Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-12-01
Completion:: 2028-11-30

Conditions

Advanced Solid Tumor
Advanced Breast Cancer
Metastatic Breast Cancer
Hormone-receptor-positive Breast Cancer
Hormone Receptor Positive Breast Carcinoma
Hormone Receptor Positive Malignant Neoplasm of Breast
HER2-negative Breast Cancer
Hormone Receptor Positive HER-2 Negative Breast Cancer
Non-small Cell Lung Cancer

Interventions

DRUG

No Results Yet

NCT06113939 | NOT_YET_RECRUITING | PHASE4

60 participants

Prevention of Infection of the Respiratory Tract Through Application of Non-Invasive Methods of Secretion Suctioning

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2026-09-15
Completion:: 2028-12-30

Conditions

Intubation Complication
Stroke, Ischemic
Stroke Hemorrhagic
Head Trauma
Cardiac Arrest
Ventilator Associated Pneumonia
Airway Clearance Impairment

Interventions

DEVICE
DRUG

No Results Yet

NCT06112743 | ACTIVE_NOT_RECRUITING | PHASE4

63 participants

A Study to Evaluate Mavacamten Impact on Myocardial Structure in Participants With Symptomatic Obstructive Hypertrophic Cardiomyopathy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2024-01-24
Completion:: 2026-07-16

Conditions

Cardiomyopathy, Hypertrophic

Interventions

DRUG

No Results Yet

NCT06106373 | COMPLETED | NA

20 participants

iotaSOFT Pediatric Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2022-05-17
Completion:: 2024-10-24

Conditions

Hearing Loss, Sensorineural
Hearing Loss, Bilateral
Hearing Loss, Unilateral

Interventions

DEVICE

Results Available

NCT06099288 | RECRUITING | NA

257 participants

Strong Families Start at Home/Familias Fuertes Comienzan en Casa

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2024-01-01
Completion:: 2027-11-01

Conditions

Metabolic Syndrome, Protection Against
Diet, Healthy

Interventions

BEHAVIORAL

No Results Yet

NCT06092476 | ACTIVE_NOT_RECRUITING | NA

18 participants

Trial to Evaluate Efficacy+Safety of Revita DMR Treatment Paradigm 1 and Retreatment in Type 2 Diabetes Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2024-08-09
Completion:: 2027-03-01

Conditions

Diabetes Mellitus, Type 2

Interventions

DEVICE
OTHER

No Results Yet

NCT06091865 | RECRUITING | PHASE3

904 participants

A Study to Compare How Well Odronextamab Combined With Chemotherapy Works and How Safe it is Against Rituximab Combined With Chemotherapy, in Adult Patients With Previously Untreated Diffuse Large B-cell Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-12-13
Completion:: 2028-03-30

Conditions

Diffuse Large B-cell Lymphoma (DLBCL)

Interventions

DRUG

No Results Yet

NCT06090864 | RECRUITING | PHASE1/PHASE2

31 participants

ATLCAR.CD30.CCR4 for CD30+ HL ATLCAR.CD30.CCR4 Cells

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2024-04-25
Completion:: 2028-08-03

Conditions

Hodgkin Lymphoma
Relapse
Refractory

Interventions

DRUG
BIOLOGICAL

No Results Yet

NCT06085781 | RECRUITING | NA

60 participants

A Study of Head and Neck MRI and Tumor Microenvironment Biomarkers

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2024-01-29
Completion:: 2027-01-15

Conditions

Squamous Cell Carcinoma of Head and Neck

Interventions

OTHER

No Results Yet

NCT06069141 | RECRUITING | NA

688 participants

Comparisons of Treatment Responses of Early Syphilis to Benzathine Penicillin G With or Without Doxycycline

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2024-01-01
Completion:: 2027-12-31

Conditions

Early Syphilis, Latent, Serological Relapse After Treatment

Interventions

DRUG

No Results Yet

NCT06066528 | COMPLETED | PHASE3

755 participants

A Study to Test Whether Survodutide (BI 456906) Helps People Living With Overweight or Obesity Who Also Have Diabetes to Lose Weight

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-11-27
Completion:: 2025-12-12

Conditions

Obesity
Diabetes Mellitus, Type 2

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT06061614 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1

15 participants

Safety and Efficacy Study of NGGT002 in PKU Adult Subjects

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-03-30
Completion:: 2028-12-30

Conditions

Phenylketonurias

Interventions

GENETIC

No Results Yet

NCT06060743 | COMPLETED | NA

88 participants

Examining the Effect of Mobile Application on Insulin Use Perception and Self-Management

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2024-01-01
Completion:: 2024-05-01

Conditions

Type 2 Diabetes Treated With Insulin

Interventions

OTHER

No Results Yet

NCT06056895 | ACTIVE_NOT_RECRUITING | PHASE2

12 participants

Triple Immune Checkpoint Inhibition for Advanced or Metastatic PD-(L)1 Refractory Merkel Cell Carcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-11-08
Completion:: 2027-01-31

Conditions

Unresectable Clinical Stage III Merkel Cell Carcinoma AJCC v8
Clinical Stage IV Merkel Cell Carcinoma AJCC v8
Merkel Cell Carcinoma

Interventions

PROCEDURE
BIOLOGICAL
DRUG

No Results Yet

NCT06056297 | RECRUITING | PHASE3

176 participants

A Study of Mavorixafor in Participants With Congenital and Acquired Primary Autoimmune and Idiopathic Chronic Neutropenic Disorders Who Are Experiencing Recurrent and/or Serious Infections

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2024-06-06
Completion:: 2027-09-30

Conditions

Neutropenia

Interventions

DRUG

No Results Yet

NCT06055920 | ACTIVE_NOT_RECRUITING | NA

1200 participants

The PEERLESS II Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-11-17
Completion:: 2026-08-31

Conditions

Pulmonary Embolism

Interventions

DEVICE
DRUG

No Results Yet

NCT06049212 | ACTIVE_NOT_RECRUITING | PHASE1

30 participants

Sacituzumab Tirumotecan (MK-2870) as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors (MK-2870-008)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-10-26
Completion:: 2026-12-31

Conditions

Non-small Cell Lung Cancer
Solid Tumors
Programmed Cell Death-1 (PD1, PD-1)
Programmed Cell Death 1 Ligand 1(PDL1, PD-L1)
Programmed Cell Death 1 Ligand 2 (PDL2, PD-L2)

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT06041581 | ENROLLING_BY_INVITATION | NA

200 participants

SHADES Mechanistic Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2024-04-25
Completion:: 2027-07-31

Conditions

Insomnia
Insomnia Chronic
Insomnia, Primary
Sleep Disturbance
Sleep Disorder
Cardiovascular Diseases
Heart Diseases
Coronary Artery Disease
Stroke
Autonomic Dysfunction
Systemic Inflammatory Response
Metabolic Disease

Interventions

BEHAVIORAL
OTHER

No Results Yet

NCT06030128 | COMPLETED | NA

150 participants

Core Stabilization Exercise Therapy in Chronic Lower Back Back Management in Community Dwelling Older Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-09-15
Completion:: 2025-05-01

Conditions

Chronic Low-back Pain
Older Adults
Core Stabilization Exercise Therapy

Interventions

BEHAVIORAL

No Results Yet

NCT05995821 | RECRUITING

1250 participants

Immunobiology Blood and Tissue Collection of Upper Aerodigestive Malignancies

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-06
Start Date:: 2016-08-25
Completion:: 2028-08-25

Conditions

Head and Neck Cancer
Lung Cancer
Gastrointestinal Cancer

Interventions

OTHER

No Results Yet

NCT05990465 | RECRUITING | PHASE1

12 participants

LV20.19 CAR T-Cells in Combination With Pirtobrutinib for Relapsed, Refractory B-cell Malignancies

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2025-02-06
Completion:: 2028-07-31

Conditions

Non Hodgkin Lymphoma
Diffuse Large B Cell Lymphoma
Follicular Lymphoma
Marginal Zone Lymphoma
Mantle Cell Lymphoma
Burkitt Lymphoma

Interventions

DRUG

No Results Yet

NCT05988385 | RECRUITING | NA

200 participants

The Effects of Successful OSA Treatment on Memory and AD Biomarkers in Older Adults Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2024-08-29
Completion:: 2027-06-30

Conditions

Obstructive Sleep Apnea
Cognitive Decline

Interventions

DEVICE

No Results Yet

NCT05984238 | COMPLETED | NA

33 participants

A Trial to Evaluate Safety, Feasibility and Efficacy of Endoscopic Duodenal PEF Therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-08-03
Completion:: 2025-03-21

Conditions

Diabetes Mellitus, Type 2

Interventions

DEVICE
DRUG
OTHER

No Results Yet

NCT05976763 | RECRUITING | PHASE3

421 participants

Testing Continuous Versus Intermittent Treatment With the Study Drug Zanubrutinib for Older Patients With Previously Untreated Mantle Cell Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-10-20
Completion:: 2038-08-31

Conditions

Mantle Cell Lymphoma

Interventions

PROCEDURE
OTHER
DRUG
BIOLOGICAL

No Results Yet

NCT05958342 | RECRUITING | PHASE2

1050 participants

CAlcium and VAsopressin Following Injury Early Resuscitation (CAVALIER) Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2024-06-30
Completion:: 2027-03-31

Conditions

Trauma
Hemorrhage

Interventions

DRUG

No Results Yet

NCT05952856 | COMPLETED | PHASE3

2912 participants

A Study of Enlicitide Decanoate (MK-0616 Oral PCSK9 Inhibitor) in Adults With Hypercholesterolemia (MK-0616-013) CORALreef Lipids

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-08-10
Completion:: 2025-07-28

Conditions

Hypercholesterolemia
Familial Hypercholesterolemia

Interventions

DRUG

Results Available

NCT05952024 | RECRUITING | PHASE2

80 participants

Study of Acalabrutinib and Rituximab in Untreated Elderly and/or Frail Patients With DLBCL

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2024-07-16
Completion:: 2029-04-22

Conditions

Diffuse Large B-Cell Lymphoma

Interventions

DRUG
BIOLOGICAL

No Results Yet

NCT05944224 | RECRUITING | PHASE1/PHASE2

63 participants

A Study to Efficacy and Safety of SPH4336 Monotherapy or in Combination With Cadonilimab in Patients With Advanced Solid Tumors.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-10-17
Completion:: 2026-12-31

Conditions

Advanced Solid Tumors

Interventions

DRUG

No Results Yet

NCT05942313 | RECRUITING

100 participants

Predicting and Preventing Adverse Maternal and Child Outcomes of Opioid Use Disorder in Pregnancy

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-08-28
Completion:: 2026-12-01

Conditions

Opioid Use Disorder
Pregnancy Related

Interventions

DRUG

No Results Yet

NCT05908240 | ACTIVE_NOT_RECRUITING | NA

520 participants

Prevention of Cardiovascular Disease and Mortality in Patients With Psoriasis or Psoriatic Arthritis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-06-15
Completion:: 2026-09-30

Conditions

Psoriasis
Psoriatic Arthritis
Psoriatic Conditions
Cardiovascular Diseases

Interventions

OTHER

No Results Yet

NCT05900427 | TERMINATED | PHASE4

78 participants

Effects on Postoperative Pain of Liposomal Bupivacaine in Interscalene Blocks for Total Shoulder Arthroplasty Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-10-23
Completion:: 2025-10-05

Conditions

Total Shoulder Arthroplasty
Reverse Total Shoulder Arthroplasty

Interventions

DRUG

Results Available

NCT05886920 | RECRUITING | PHASE1/PHASE2

67 participants

A Phase 1/2 Study of D3S-002 as Monotherapy or Combination Therapy in Adult Subjects With Advanced Solid Tumors With MAPK Pathway Mutations

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-07-10
Completion:: 2028-08-31

Conditions

Advanced Solid Tumors With MAPK Pathway Mutations

Interventions

DRUG

No Results Yet

NCT05879211 | ENROLLING_BY_INVITATION | NA

5000 participants

Goal Concordant Care Learning Laboratory

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-07-12
Completion:: 2026-12-31

Conditions

Cancer
Heart Failure
Copd
Dementia

Interventions

BEHAVIORAL

No Results Yet

NCT05877599 | RECRUITING | PHASE1

45 participants

A Study of NT-175 in Adult Participants With Advanced Malignancies That Are Positive for HLA-A*02:01 and the TP53 R175H Mutation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-07-12
Completion:: 2029-07-31

Conditions

Non-small Cell Lung Cancer
Head and Neck Squamous Cell Carcinoma
Colorectal Carcinoma
Pancreatic Adenocarcinoma
Breast Cancer
Other Solid Tumors
Ovarian Cancer
Myeloid Neoplasms (AML/MDS)

Interventions

BIOLOGICAL

No Results Yet

NCT05874297 | RECRUITING | NA

50 participants

Online Nutrition Education to Decrease the Side Effects of Chemotherapy in Patients With Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2026-07-15
Completion:: 2027-12-31

Conditions

Anatomic Stage I Breast Cancer AJCC v8
Anatomic Stage II Breast Cancer AJCC v8
Anatomic Stage III Breast Cancer AJCC v8

Interventions

OTHER
BEHAVIORAL

No Results Yet

NCT05870488 | ACTIVE_NOT_RECRUITING | PHASE4

110 participants

iFuse TORQ for the Treatment of Sacroiliac Joint Dysfunction

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-05-23
Completion:: 2025-04-23

Conditions

Sacroiliac Joint Dysfunction
Sacroiliac; Fusion
Sacroiliac Disorder
Sacroiliac Joint Pain

Interventions

DEVICE

No Results Yet

NCT05868265 | ACTIVE_NOT_RECRUITING | PHASE2

9 participants

A Study of Enfortumab Vedotin in People With Urothelial Carcinoma of the Upper Urinary Tract

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-06-02
Completion:: 2027-06-02

Conditions

Urothelial Carcinoma

Interventions

DRUG
PROCEDURE

No Results Yet

NCT05867186 | RECRUITING

100 participants

Fit to Fight Childhood Cancer

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-06-20
Completion:: 2027-07-31

Conditions

Pediatric Oncology

Interventions

BEHAVIORAL

No Results Yet

NCT05850676 | COMPLETED

54 participants

Disentangling the Role of Depression in Hypersomnia

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-08-01
Completion:: 2026-08-03

Conditions

Hypersomnia

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05849064 | COMPLETED | NA

56 participants

Concussion Treatment in Older Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-09-07
Completion:: 2026-06-15

Conditions

Concussion, Mild

Interventions

BEHAVIORAL

No Results Yet