Disentangling the Role of Depression in Hypersomnia
NCT05850676 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 45
Last updated 2025-07-16
Summary
Individuals who have disorders of hypersomnolence (excessive sleepiness) often report symptoms of depression. The goal of this study is to further understand of the relationship between depression and hypersomnia by examining mood-relevant domains of slow wave sleep and reward function.
Conditions
- Hypersomnia
Interventions
- DIAGNOSTIC_TEST
-
Sleep study
Participants will spend two nights in the Penn Sleep Center
Sponsors & Collaborators
- collaborator INDUSTRY
- lead OTHER
Principal Investigators
-
Philip Gehrman, PhD · University of Pennsylvania
Eligibility
- Min Age
- 21 Years
- Max Age
- 55 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-08-01
- Primary Completion
- 2026-05-30
- Completion
- 2026-06-30
Countries
- United States
Study Locations
More Related Trials
-
UTSW Depression Cohort: A Longitudinal Study of Depression
NCT02697487 ·Status: COMPLETED
-
Sleep Deprivation Plus Paroxetine for Treating Major Depression in Elderly Individuals
NCT00178035 ·Status: COMPLETED ·Phase: PHASE4
-
Cymbalta for Depression as a Complication of Bereavement
NCT00658931 ·Status: UNKNOWN ·Phase: PHASE4
-
Sleep-Wake Patterns on Illness Trajectories and Treatment Response in MDD
NCT06181110 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
FMRI Study of Performance During a Probabilistic Reversal Learning Task in Depression
NCT00075296 ·Status: COMPLETED
-
Sleep Therapy for Insomnia and Depression
NCT02943278 ·Status: COMPLETED ·Phase: NA
-
A Study to Evaluate Sleep Electroencephalogram (EEG) Features (Brain Activity While Sleeping) in Participants With Major Depressive Disorder (MDD)
NCT07258485 ·Status: RECRUITING
-
Altering Default Mode Network Activity With Transcranial Focused Ultrasound to Reduce Depressive Symptoms
NCT06320028 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1/PHASE2
-
Heart Rate Variability in Depression
NCT02525978 ·Status: COMPLETED ·Phase: NA
-
Depression Prevention in Older Spousally-bereaved Adults
NCT04016896 ·Status: COMPLETED ·Phase: NA
-
Recurrence Markers, Cognitive Burden and Neurobiological Homeostasis in Late-Life Depression
NCT05331599 ·Status: ACTIVE_NOT_RECRUITING
-
Establish a Specific Cohort Database for Depressive Disorders
NCT05095662 ·Status: ACTIVE_NOT_RECRUITING
-
Sleep and Healthy Aging Research for Depression (SHARE-D) Study
NCT03256760 ·Status: COMPLETED ·Phase: PHASE1
-
Brain Imaging in Depression
NCT00050700 ·Status: COMPLETED
-
Determining Changes in Brain Structure Associated With Symptoms of Late-life Depression
NCT00178087 ·Status: COMPLETED
-
Pilot Study: Investigating Mood Changes After Slow-wave Enhancement
NCT05146427 ·Status: WITHDRAWN ·Phase: NA
-
Insulin Resistance in Patients With Major Depression
NCT01106313 ·Status: COMPLETED
-
Cohort of Patients Suffering From Major Depressive Episode With Evaluation of Sleep, Circadian Rhythms and Psychiatric Disorders
NCT05866991 ·Status: RECRUITING
-
Depression and Heart Failure Disease Progression
NCT02131428 ·Status: COMPLETED
-
Rhythm and Depression
NCT02857036 ·Status: UNKNOWN ·Phase: NA
-
Neurocognitive Outcomes of Depression in the Elderly
NCT00570583 ·Status: COMPLETED
-
Imagery Rescripting as Treatment for Depression
NCT05976945 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Sleep Modulation as Antidepressant Randomized Trial
NCT05685771 ·Status: COMPLETED ·Phase: NA
-
Multi-Omic, Clinomic and Digitomic Attributes of Major Depression for Integrative Analytics
NCT05910957 ·Status: ENROLLING_BY_INVITATION
-
Neurocardiac Control in Major Depression
NCT00084162 ·Status: COMPLETED