Clinical Trials

NCT05261399 | ACTIVE_NOT_RECRUITING | PHASE3

341 participants

Savolitinib Plus Osimertinib Versus Platinum-based Doublet Chemotherapy in Participants With Non-Small Cell Lung Cancer Who Have Progressed on Osimertinib Treatment

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2022-08-03

Completion:

2026-07-06

Conditions

• Carcinoma
• Non-Small-Cell Lung

Interventions

• DRUG

No Results Yet

NCT05232916 | RECRUITING | PHASE3

2250 participants

Phase 3 Study to Evaluate the Efficacy and Safety of HER2/Neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/Neu Positive Subjects

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2022-12-16

Completion:

2031-12-31

Conditions

• Breast Cancer

Interventions

• BIOLOGICAL

No Results Yet

NCT05226507 | TERMINATED | PHASE1

45 participants

A Phase 1 Clinical Study of NXP800 in Subjects With Advanced Cancers and Expansion in Subjects With Ovarian Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2021-12-31

Completion:

2025-01-01

Conditions

• Advanced Solid Tumor
• Ovarian Cancer
• Ovarian Clear Cell Carcinoma
• Ovarian Clear Cell Tumor
• Ovarian Clear Cell Adenocarcinoma
• Ovarian Endometrioid Adenocarcinoma
• Ovarian Endometrioid Tumor
• ARID1A Gene Mutation

Interventions

• DRUG

No Results Yet

NCT05210374 | RECRUITING | PHASE1

24 participants

Disulfiram With Copper Gluconate and Liposomal Doxorubicin in Treatment-Refractory Sarcomas

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-03-09

Completion:

2026-09-01

Conditions

• Relapsed Sarcomas

Interventions

• DRUG

No Results Yet

NCT05207059 | ACTIVE_NOT_RECRUITING | NA

500 participants

Healthy Early Life Moments in Singapore

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2022-03-18

Completion:

2027-12-31

Conditions

• Metabolic Disease
• Mental Health Wellness 1
• Lifestyle Risk Reduction
• Maternal Obesity

Interventions

• BEHAVIORAL

No Results Yet

NCT05176808 | COMPLETED | NA

117 participants

Telehealth Parent-Implemented Intervention for Young Children With Autism Spectrum Disorder (ASD)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2022-02-07

Completion:

2026-04-10

Conditions

• Autism Spectrum Disorder
• Autistic Disorder
• Active Autistic Disorder
• Autism
• Asperger Syndrome
• PDD-NOS
• Social Communication Delay
• Mixed Expressive Receptive Language Disorder
• Other Symbolic Dysfunctions

Interventions

• BEHAVIORAL

No Results Yet

NCT05172934 | COMPLETED | PHASE2

20 participants

Adjunctive Intra-arterial Tenecteplase Following Mechanical Thrombectomy Pilot Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2022-04-11

Completion:

2023-09-12

Conditions

• Ischemic Stroke

Interventions

• DRUG

Results Available

NCT05107115 | COMPLETED | PHASE2

160 participants

Rilzabrutinib for the Treatment of Chronic Spontaneous Urticaria in Patients Who Remain Symptomatic Despite the Use of H1 Antihistamine

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2021-11-24

Completion:

2023-07-19

Conditions

• Chronic Spontaneous Urticaria

Interventions

• DRUG

Results Available

NCT05093634 | COMPLETED | PHASE3

296 participants

EMANATE: A Study of Setmelanotide in Patients With Specific Gene Variants in the MC4R Pathway

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2021-12-10

Completion:

2025-12-22

Conditions

• Obesity
• Genetic Obesity

Interventions

• DRUG

No Results Yet

NCT05090267 | RECRUITING | NA

80 participants

The Path Study: Cognitive and Inflammation Targeted Gut-brain Interventions in Alcohol; Probiotics, Alcohol, Transcutaneous Vagus Nerve Stimulation, and HIV Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2022-06-01

Completion:

2026-12-30

Conditions

• Cognition
• Gut Microbiome

Interventions

• DIETARY_SUPPLEMENT
• DEVICE

No Results Yet

NCT05086497 | RECRUITING | NA

155 participants

WBSI Guided Personalized Delivery of TTFields

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-01-15

Completion:

2027-06-30

Conditions

• GBM
• Glioma Glioblastoma Multiforme
• Tumor, Brain

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT05081037 | ACTIVE_NOT_RECRUITING | NA

208 participants

Integrated Hyperglycaemia Incentivised Postnatal Surveillance Study (I-HIPS)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2021-09-06

Completion:

2028-07-15

Conditions

• Gestational Diabetes
• Glucose Metabolism Disorders
• Metabolic Disease

Interventions

• DEVICE

No Results Yet

NCT05066542 | ACTIVE_NOT_RECRUITING | NA

60 participants

Recreational Basketball to Increase Participation in Diabetes Prevention

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2021-06-11

Completion:

2023-11-30

Conditions

• Type 2 Diabetes
• PreDiabetes

Interventions

• BEHAVIORAL

No Results Yet

NCT05064709 | RECRUITING | NA

1500 participants

Assessment of CCM in HF With Higher Ejection Fraction

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2022-02-03

Completion:

2029-02-01

Conditions

• Heart Failure
• Heart Failure With Preserved Ejection Fraction
• Heart Failure With Mid Range Ejection Fraction
• Heart Failure With Moderately Reduced Ejection Fraction
• Diastolic Heart Failure

Interventions

• DEVICE

No Results Yet

NCT05055050 | ACTIVE_NOT_RECRUITING | PHASE1

10 participants

A Window of Opportunity Phase I Study of UGN-201 in Patients With Bladder Cancer Undergoing Radical Cystectomy Protocol #: 2021-0630

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2022-01-24

Completion:

2026-08-31

Conditions

• Bladder Cancer
• Bladder

Interventions

• DRUG

No Results Yet

NCT05039840 | ACTIVE_NOT_RECRUITING | PHASE2

109 participants

Efficacy and Safety of Frexalimab (SAR441344) in the Treatment of Systemic Lupus Erythematosus

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2021-11-10

Completion:

2026-09-03

Conditions

• Systemic Lupus Erythematosus

Interventions

• DRUG

No Results Yet

NCT05028621 | SUSPENDED | NA

135 participants

Molecular Basis of Langerhans and Non-Langerhans Cell Histiocytic Neoplasms and Castleman Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2021-06-18

Completion:

2026-09-30

Conditions

• Castleman's Disease (CD)
• Langerhans Cell Histiocytosis (LCH)
• Non-Langerhans-Cell Histiocytosis

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT05017740 | ACTIVE_NOT_RECRUITING | NA

47 participants

PICSI RCT in Couples With a Previous Poor Fertilisation Cycle in IVF

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2022-03-15

Completion:

2026-12-31

Conditions

• Infertility
• IVF

Interventions

• PROCEDURE

No Results Yet

NCT05002478 | RECRUITING | NA

14 participants

Infants With Severe Acute Respiratory Distress Syndrome: The Prone Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2022-07-30

Completion:

2027-07-31

Conditions

• Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS)
• Surfactant Dysfunction
• Infant

Interventions

• OTHER

No Results Yet

NCT04994808 | TERMINATED | PHASE2

23 participants

Treosulfan-Based Versus Clofarabine-Based Conditioning Before Donor Hematopoietic Stem Cell Transplant for the Treatment of Myelodysplastic Syndromes or Acute Myeloid Leukemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-08-11

Completion:

2026-01-22

Conditions

• Acute Myeloid Leukemia
• Myelodysplastic Syndrome

Interventions

• DRUG
• PROCEDURE
• RADIATION

No Results Yet

NCT04969094 | ACTIVE_NOT_RECRUITING | NA

81 participants

Reducing Fall Risk With NMES

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2022-01-04

Completion:

2026-12-20

Conditions

• Falls

Interventions

• OTHER

No Results Yet

NCT04967365 | COMPLETED

755 participants

Post-Intensive Care Syndrome - Pediatrics (PICS-p): Longitudinal Cohort Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2021-07-27

Completion:

2026-01-31

Conditions

• Critical Illness
• Post Intensive Care Unit Syndrome

No Results Yet

NCT04930744 | COMPLETED | PHASE2

112 participants

Safety and Tolerability of Metformin in People With Tuberculosis (TB) and Human Immunodeficiency Virus (HIV)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2022-03-04

Completion:

2025-04-29

Conditions

• Tuberculosis
• Pulmonary Tuberculosis
• HIV Coinfection

Interventions

• DRUG

Results Available

NCT04862325 | COMPLETED | NA

158 participants

SOPHIE Trial: Surgery in Ovarian Cancer With PreHabilitation In ERAS

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2021-04-20

Completion:

2026-04-28

Conditions

• Advanced Ovarian Cancer

Interventions

• OTHER

No Results Yet

NCT04826237 | TERMINATED | PHASE4

3 participants

Oral Statins and Protection From Hearing Loss

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-02-09

Completion:

2025-10-30

Conditions

• Sudden Sensorineural Hearing Loss

Interventions

• DRUG

No Results Yet

NCT04766190 | ACTIVE_NOT_RECRUITING | NA

254 participants

DISCO: A Patient Intervention to Reduce the Financial Burden of Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2021-02-10

Completion:

2027-08-31

Conditions

• Financial Toxicity
• Cancer
• Question Prompt List
• Breast Cancer
• Prostate Cancer

Interventions

• BEHAVIORAL

No Results Yet

NCT04743791 | RECRUITING | PHASE4

30 participants

Measuring the Effect of Dupilumab Treatment on Mucociliary Clearance (MCC) in Subjects With Moderate to Severe Asthma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2022-10-17

Completion:

2027-12-31

Conditions

• Asthma

Interventions

• DRUG
• OTHER

No Results Yet

NCT04730869 | COMPLETED | NA

18 participants

Metabolic Therapy Program In Conjunction With Standard Treatment For Glioblastoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2021-05-26

Completion:

2025-02-18

Conditions

• Glioblastoma

Interventions

• OTHER

No Results Yet

NCT04717349 | RECRUITING

11000 participants

Data Collection Study of Pediatric and Adolescent Gynecology Conditions

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2021-04-21

Completion:

2039-12-02

Conditions

• Disorders of Sex Development (DSD)
• Pediatric and Adolescent Cancers of the Genital Tract
• Reproductive Endocrine Conditions in Puberty
• Structural Gynecologic Conditions Including Vulvar and Vaginal Conditions

No Results Yet

NCT04715191 | RECRUITING | PHASE1

24 participants

Interleukin-15 and -21 Armored Glypican-3-specific Chimeric Antigen Receptor Expressed in T Cells for Pediatric Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-05-24

Completion:

2027-08-01

Conditions

• Liver Cancer
• Rhabdomyosarcoma
• Malignant Rhabdoid Tumor
• Liposarcoma
• Wilms Tumor
• Yolk Sac Tumor

Interventions

• GENETIC

No Results Yet

NCT04640142 | ACTIVE_NOT_RECRUITING | PHASE3

50 participants

Study to Evaluate the Pharmacokinetics, Efficacy, Tolerability, and Safety of Subcutaneous Human Immunoglobulin (Newnorm) in Patients With Primary Immunodeficiency Diseases

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2021-08-04

Completion:

2026-09-30

Conditions

• Primary Immune Deficiency

Interventions

• BIOLOGICAL

No Results Yet

NCT04599504 | COMPLETED | PHASE2/PHASE3

16 participants

Pharmacological and Behavioral Treatment After Bariatric Surgery: Medication Change for Non-Responders (Stage 2b)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2022-01-02

Completion:

2026-06-04

Conditions

• Loss-of-control Eating
• Obesity/Overweight

Interventions

• DRUG
• OTHER

Results Available

NCT04527549 | TERMINATED | PHASE2

5 participants

Testing Dabrafenib and Trametinib With or Without Hydroxychloroquine in Stage IIIC or IV BRAF V600E/K Melanoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2021-06-01

Completion:

2024-01-08

Conditions

• Clinical Stage IV Cutaneous Melanoma AJCC v8
• Locally Advanced Melanoma
• Pathologic Stage IIIC Cutaneous Melanoma AJCC v8
• Pathologic Stage IV Cutaneous Melanoma AJCC v8
• Unresectable Melanoma

Interventions

• DRUG

Results Available

NCT04469959 | COMPLETED | PHASE2

79 participants

Dopaminergic Dysfunction in Late-Life Depression

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2021-02-15

Completion:

2026-04-29

Conditions

• Late Life Depression
• Cognitive Decline
• Depressive Disorder, Treatment-Resistant
• Levodopa
• Gait Impairment

Interventions

• DRUG

No Results Yet

NCT04469686 | COMPLETED | PHASE3

200 participants

Phase 3 Study to Evaluate the Safety and Efficacy of Hydrocortisone Acetate Suppositories

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2020-12-10

Completion:

2024-09-19

Conditions

• Ulcerative Proctitis

Interventions

• COMBINATION_PRODUCT

Results Available

NCT04455048 | COMPLETED | NA

84 participants

The Effectiveness of Manipulation Treatment in Cervical Region

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2019-02-02

Completion:

2023-10-16

Conditions

• Neck Pain

Interventions

• OTHER

No Results Yet

NCT04450459 | COMPLETED

121 participants

Impact of Spiroergometer Parameters as Diagnostic Marker of Cardiac Ischemia in Pts. With Stable Angina Compared to FFR.

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2019-01-02

Completion:

2025-08-25

Conditions

• Stable Angina

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT04386967 | COMPLETED | PHASE1/PHASE2

44 participants

OH2 Injection in Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2018-11-22

Completion:

2026-06-02

Conditions

• Solid Tumor
• Melanoma

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT04352569 | COMPLETED | NA

25 participants

Efficacy of tDCS in the Treatment of Resistant Auditory Hallucinations in Schizophrenia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2016-05-03

Completion:

2025-03-31

Conditions

• Schizophrenia
• Hallucinations
• Refractory Schizophrenia

Interventions

• DEVICE

No Results Yet

NCT04332341 | RECRUITING | EARLY_PHASE1

20 participants

Study of Nicotinamide Riboside Supplementation in Allogeneic Hematopoietic Cell Transplantation

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2020-05-19

Completion:

2026-09-30

Conditions

• Allogeneic Hematopoietic Cell Transplantation

Interventions

• DRUG

No Results Yet