Clinical Trials

NCT06014801 | RECRUITING | PHASE2/PHASE3

400 participants

Low-intensity Versus Medium-intensity Continuous Kidney Replacement Therapy for Critically Ill Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2023-10-30

Completion:

2029-09-30

Conditions

• Acute Kidney Injury Requiring Continuous Renal Replacement Therapy

Interventions

• DRUG

No Results Yet

NCT06012136 | COMPLETED | PHASE1

85 participants

A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of a Single Suspension Injection of Investigational Capsid Inhibitors Compared to Placebo in Healthy Adults

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2023-08-24

Completion:

2026-06-09

Conditions

• HIV Infections

Interventions

• DRUG

No Results Yet

NCT06006403 | COMPLETED | PHASE1/PHASE2

5 participants

Safety and Efficacy of CD123-targeted CAR-NK for Relapsed/Refractory Acute Myeloid Leukemia or Blastic Plasmacytoid Dendritic Cell Neoplasm

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2024-03-28

Completion:

2025-09-25

Conditions

• Acute Myeloid Leukemia
• Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)
• Relapse Leukemia
• Refractory Leukemia

Interventions

• BIOLOGICAL

No Results Yet

NCT06005623 | COMPLETED | NA

152 participants

Motivational Feedback Following Total or Unicompartmental Knee Arthroplasty

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2023-09-15

Completion:

2025-04-01

Conditions

• Knee Arthropathy

Interventions

• DEVICE

No Results Yet

NCT06001749 | RECRUITING | PHASE2

15 participants

Psilocybin in Cancer Pain Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2024-09-23

Completion:

2026-10-01

Conditions

• Opioid-Related Disorders
• Pain Management
• Pain Management and Care
• Advanced Cancer
• Advanced Cancers

Interventions

• DRUG

No Results Yet

NCT05985135 | WITHDRAWN | NA

0 participants

Impact of Insulin Deprivation and Hyperglycemia on Plasma Protein Synthesis in People With Type 1 Diabetes Mellitus

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2026-06-01

Completion:

2026-07-31

Conditions

• Type 1 Diabetes

Interventions

• PROCEDURE
• OTHER
• DIETARY_SUPPLEMENT

No Results Yet

NCT05972564 | RECRUITING | PHASE1/PHASE2

74 participants

The Effect of SGLT2 Inhibition on Adipose Inflammation and Endothelial Function

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2023-09-06

Completion:

2026-09-30

Conditions

• Obesity
• Metabolic Syndrome

Interventions

• DRUG

No Results Yet

NCT05964465 | COMPLETED | PHASE4

60 participants

Mechanisms of Smell Improvement With Dupilumab.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2023-08-10

Completion:

2025-01-30

Conditions

• Chronic Rhinosinusitis With Nasal Polyps

Interventions

• DRUG

Results Available

NCT05958407 | COMPLETED | PHASE3

235 participants

A 32-week Trial to Evaluate the Efficacy and Safety of Tralokinumab in Subjects With Moderate-to-severe Atopic Hand Eczema Who Are Candidates for Systemic Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2023-08-28

Completion:

2025-05-05

Conditions

• Atopic Dermatitis
• Atopic Hand Eczema

Interventions

• DRUG

Results Available

NCT05945355 | RECRUITING | NA

76 participants

Mechanistic Study of Inspiratory Training in Childhood Asthma (MICA)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2024-08-01

Completion:

2027-10-30

Conditions

• Asthma in Children
• Obesity
• Pediatric Obesity
• Pediatric Asthma

Interventions

• DEVICE

No Results Yet

NCT05943626 | RECRUITING | NA

20 participants

Circadian Intervention to Improve Cardiometabolic Health

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2023-06-13

Completion:

2026-12-31

Conditions

• Cardiometabolic Syndrome
• Type 2 Diabetes
• Sleep
• Time Restricted Feeding
• Lifestyle Factors
• Overweight and Obesity
• Insulin Sensitivity
• Eating Habit
• Sleep Hygiene

Interventions

• BEHAVIORAL

No Results Yet

NCT05927571 | RECRUITING | PHASE1

120 participants

A Study Evaluating the Safety, Pharmacokinetics, and Activity of the Combination of Cevostamab and Elranatamab in Participants With Relapsed or Refractory Multiple Myeloma (R/R MM)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2023-08-10

Completion:

2027-07-31

Conditions

• Relapsed or Refractory Multiple Myeloma

Interventions

• DRUG

No Results Yet

NCT05902689 | ACTIVE_NOT_RECRUITING | NA

42 participants

Application of Sticky Bone and Bio-Oss Collagen in Alveolar Ridge Preservation

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2023-06-15

Completion:

2025-04-15

Conditions

• Alveolar Bone Resorption

Interventions

• PROCEDURE

No Results Yet

NCT05886036 | RECRUITING | PHASE2

70 participants

Comparing the Effectiveness of the Immunotherapy Agents Rituximab or Mosunetuzumab in Patients With Nodular Lymphocyte-Predominant Hodgkin Lymphoma, NORM Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2024-01-23

Completion:

2026-10-31

Conditions

• Nodular Lymphocyte Predominant B-Cell Lymphoma
• Recurrent Nodular Lymphocyte Predominant B-Cell Lymphoma
• Refractory Nodular Lymphocyte Predominant B-Cell Lymphoma

Interventions

• PROCEDURE
• OTHER
• BIOLOGICAL

No Results Yet

NCT05885139 | COMPLETED | NA

34 participants

Exopulse Mollii Suit, Motor Functions & CP Children With Cerebral Palsy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2023-04-17

Completion:

2025-12-31

Conditions

• Cerebral Palsy
• Spasticity
• Muscle
• Pain Syndrome
• Hemiplegia
• Diplegia
• Tetraplegia
• Balance

Interventions

• DEVICE

No Results Yet

NCT05853705 | TERMINATED | NA

9 participants

Strong Hearts: A Remote, App-Enabled, Exercise Program for Patients With Congenital Heart Disease (Strong Hearts App)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2024-01-12

Completion:

2024-12-05

Conditions

• Congenital Heart Disease

Interventions

• BEHAVIORAL

No Results Yet

NCT05849207 | RECRUITING | PHASE1

26 participants

Post-Transplant Cyclophosphamide in Patients Aged >/= 65 Years Undergoing Haploidentical Transplant

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2023-10-24

Completion:

2027-07-01

Conditions

• Hematologic Malignancies

Interventions

• DRUG

No Results Yet

NCT05826743 | RECRUITING | NA

256 participants

Safety and Effectiveness Evaluation of the COLO-BT as an Alternative Treatment to the Ileostomy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2023-12-04

Completion:

2027-12-15

Conditions

• Colorectal Surgery
• Colorectal Cancer
• Rectal/Anal
• Ileostomy - Stoma
• Anastomotic Leakage

Interventions

• DEVICE
• OTHER

No Results Yet

NCT05814575 | COMPLETED | NA

103 participants

NEXUS - Next Generation Health Through 2D & 3D Fetal UltraSound; Building Connections to Support Maternal-fetal Health

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2023-06-08

Completion:

2025-11-30

Conditions

• Pregnancy Related
• Substance Use
• Mental Health Issue

Interventions

• BEHAVIORAL

No Results Yet

NCT05812807 | RECRUITING | PHASE3

1295 participants

Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2023-06-14

Completion:

2033-05-31

Conditions

• Anatomic Stage II Breast Cancer AJCC v8
• Early Stage Triple-Negative Breast Carcinoma
• Anatomic Stage IIIA Breast Cancer AJCC v8
• Anatomic Stage IIIB Breast Cancer AJCC v8

Interventions

• BIOLOGICAL
• OTHER
• PROCEDURE

No Results Yet

NCT05807269 | RECRUITING

50 participants

Prevention and Rehabilitation of Stroke in Uganda

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-05

Start Date:

2023-11-01

Completion:

2028-03-31

Conditions

• Stroke

No Results Yet

NCT05800873 | COMPLETED | PHASE1

31 participants

Evaluate The Efficacy, Safety, Pharmacokinetics And Pharmacodynamics Of EVER001

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2023-05-15

Completion:

2026-07-22

Conditions

• Primary Membranous Nephropathy

Interventions

• DRUG

No Results Yet

NCT05799378 | RECRUITING | PHASE3

330 participants

Effects of Stopping Hydroxychloroquine in Elderly Lupus Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2024-06-27

Completion:

2028-12-31

Conditions

• Systemic Lupus Erythematosus

Interventions

• DRUG

No Results Yet

NCT05796375 | RECRUITING | PHASE2

240 participants

Replacing Invasive Cystoscopy With Urine Testing for Non-muscle Invasive Bladder Cancer Surveillance

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2023-11-17

Completion:

2028-11-30

Conditions

• Non-muscle-invasive Bladder Cancer

Interventions

• PROCEDURE
• DIAGNOSTIC_TEST

No Results Yet

NCT05792150 | RECRUITING

1470 participants

PROOFS-Registry - Premenopausal Women With Breast Cancer Optimally Treated With OFS

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-05

Start Date:

2022-12-07

Completion:

2035-03-31

Conditions

• Female Breast Cancer

No Results Yet

NCT05788536 | RECRUITING | PHASE1/PHASE2

36 participants

A Study of DB-OTO, an Adeno-Associated Virus (AAV) Based Gene Therapy, in Children/Infants, Adolescents and Adults With Hearing Loss Due to Otoferlin Mutations

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2023-06-27

Completion:

2029-02-26

Conditions

• Congenital Hearing Loss Secondary to Biallelic Mutations of the Otoferlin Gene (OTOF)

Interventions

• GENETIC

No Results Yet

NCT05771675 | RECRUITING | EARLY_PHASE1

90 participants

Simvastatin Treatment to Improve Patient-reported Outcomes in Patients With Chronic Pancreatitis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2024-10-24

Completion:

2027-12-31

Conditions

• Recurrent Acute Pancreatitis
• Chronic Pancreatitis

Interventions

• DRUG

No Results Yet

NCT05751668 | SUSPENDED | PHASE2

98 participants

Finding an Effective Dose of GM1 to Reduce or Prevent Neuropathy (Numbness or Weakness) Due to Treatment With Paclitaxel (Phase II)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2023-11-02

Completion:

2028-03-15

Conditions

• Anatomic Stage IV Breast Cancer AJCC v8
• Chemotherapy-Induced Peripheral Neuropathy
• Metastatic Breast Carcinoma

Interventions

• DRUG
• OTHER

No Results Yet

NCT05732116 | COMPLETED

356 participants

PTSD of Surgeons or Anesthesiologists on Prognosis of Surgical Patients

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-05

Start Date:

2023-02-21

Completion:

2025-12-31

Conditions

• Post Traumatic Stress Disorder
• Postoperative Complications
• COVID-19

Interventions

• OTHER

No Results Yet

NCT05720065 | RECRUITING | PHASE2

100 participants

Peripheral TMD Pain Mechanisms and the Effect by Botulinum Toxin A

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2023-11-14

Completion:

2027-08-31

Conditions

• Temporomandibular Disorders

Interventions

• DRUG

No Results Yet

NCT05715242 | COMPLETED | NA

32 participants

Ignite Pilot: Goal Setting in a Digital Weight Loss Intervention

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2023-12-05

Completion:

2024-04-09

Conditions

• Obesity
• Overweight
• Weight Loss
• Health Behavior

Interventions

• BEHAVIORAL

Results Available

NCT05708352 | RECRUITING | PHASE2

170 participants

A Phase 2 Study of the Ketogenic Diet vs Standard Anti-cancer Diet Guidance for Patients With Glioblastoma in Combination With Standard-of-care Treatment

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2023-06-27

Completion:

2028-09-30

Conditions

• Glioblastoma Multiforme

Interventions

• BEHAVIORAL

No Results Yet

NCT05701800 | TERMINATED | PHASE1

659 participants

A Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of mRNA-1468 in Healthy Adults ≥50 Years of Age

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2023-01-23

Completion:

2025-12-31

Conditions

• Herpes Zoster

Interventions

• BIOLOGICAL

No Results Yet

NCT05677490 | RECRUITING | PHASE3

382 participants

mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2023-01-31

Completion:

2028-11-08

Conditions

• Advanced Esophageal Adenocarcinoma
• Advanced Gastric Adenocarcinoma
• Advanced Gastroesophageal Junction Adenocarcinoma
• Clinical Stage III Esophageal Adenocarcinoma AJCC v8
• Clinical Stage III Gastric Cancer AJCC v8
• Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8
• Clinical Stage IV Esophageal Adenocarcinoma AJCC v8
• Clinical Stage IV Gastric Cancer AJCC v8
• Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8
• Metastatic Esophageal Adenocarcinoma
• Metastatic Gastric Adenocarcinoma
• Metastatic Gastroesophageal Junction Adenocarcinoma
• Unresectable Esophageal Adenocarcinoma
• Unresectable Gastric Adenocarcinoma
• Unresectable Gastroesophageal Junction Adenocarcinoma

Interventions

• DRUG
• BIOLOGICAL
• PROCEDURE
• OTHER

No Results Yet

NCT05676203 | ACTIVE_NOT_RECRUITING | PHASE3

250 participants

A Trial Comparing Docetaxel 75 mg/m2 (3w) Versus Docetaxel 50 mg/m2 (2w) in Combination With Darolutamide + ADT in mHSPC Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2023-05-16

Completion:

2025-07-03

Conditions

• Metastatic Hormone-Sensitive Prostate Cancer (mHSPC)

Interventions

• DRUG

No Results Yet

NCT05673148 | RECRUITING | PHASE3

364 participants

Testing the Addition of Total Ablative Therapy to Usual Systemic Therapy Treatment for Limited Metastatic Colorectal Cancer, The ERASur Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2023-10-09

Completion:

2028-07-03

Conditions

• Metastatic Colorectal Adenocarcinoma
• Stage IV Colorectal Cancer AJCC v8

Interventions

• PROCEDURE
• DRUG

No Results Yet

NCT05668871 | COMPLETED | PHASE4

326 participants

A Study of Danning Tablet in Patients With Polypoid Lesions of Gallbladder

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2022-12-01

Completion:

2026-02-25

Conditions

• Multiple Gallbladder Polyps

Interventions

• DRUG
• BEHAVIORAL

No Results Yet

NCT05664880 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1

24 participants

A PiLot ClinicaL TrIal of ParicAlcitol for ChroNiC PancrEatitis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2023-06-01

Completion:

2027-07-31

Conditions

• Chronic Pancreatitis

Interventions

• DRUG

No Results Yet

NCT05654922 | RECRUITING | PHASE3

100 participants

Study to Evaluate ARINA-1 in the Prevention of Bronchiolitis Obliterans Progression in Participants With Bilateral Lung Transplant

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2023-04-10

Completion:

2028-02-29

Conditions

• Pre-Bronchiolitis Obliterans Syndrome

Interventions

• DRUG
• OTHER

No Results Yet

NCT05647265 | RECRUITING | PHASE2

26 participants

Testing the Addition of Immunotherapy Before Surgery for Patients With Sarcomatoid Mesothelioma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2024-11-27

Completion:

2026-12-15

Conditions

• Pleural Biphasic Mesothelioma
• Pleural Sarcomatoid Mesothelioma

Interventions

• BIOLOGICAL
• PROCEDURE

No Results Yet