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Simvastatin Treatment to Improve Patient-reported Outcomes in Patients With Chronic Pancreatitis

NCT05771675 · Status: RECRUITING · Phase: EARLY_PHASE1 · Type: INTERVENTIONAL · Enrollment: 90

Last updated 2026-02-27

No results posted yet for this study

Summary

The purpose of this pilot study to examine the feasibility and acceptability of simvastatin in adults with Recurrent Acute Pancreatitis (RAP) and Chronic Pancreatitis (CP).

Conditions

  • Recurrent Acute Pancreatitis
  • Chronic Pancreatitis

Interventions

DRUG

Simvastatin

40Mg Oral Tablet

DRUG

Placebo

Matching Simvastatin Placebo tablet

Sponsors & Collaborators

  • United States Department of Defense

    collaborator FED

  • Cedars-Sinai Medical Center

    lead OTHER

Principal Investigators

  • Stephen Pandol, MD · Cedars-Sinai Medical Center

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-10-24
Primary Completion
2026-12-31
Completion
2027-06-30
FDA Drug
Yes

Countries

  • United States

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05771675 on ClinicalTrials.gov