Clinical Trials

NCT04919122 | ACTIVE_NOT_RECRUITING

468 participants

Outcomes Database to prospectivelY aSSEss the Changing TherapY Landscape in Renal Cell Carcinoma

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-05

Start Date:

2022-04-01

Completion:

2026-12-31

Conditions

• Metastatic Renal Cell Carcinoma

No Results Yet

NCT04906096 | RECRUITING | PHASE2

25 participants

Paxalisib (GDC-0084) In Recurrent Or Refractory PCNSL

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2021-06-01

Completion:

2026-12-01

Conditions

• Primary Central Nervous System Lymphoma
• Non-Hodgkin Lymphoma of Extranodal Site

Interventions

• DRUG

No Results Yet

NCT04900623 | RECRUITING | PHASE2

145 participants

Risk-adapted Therapy in HPV+ Oropharyngeal Cancer Using Circulating Tumor (ct)HPV DNA Profile - The ReACT Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2021-07-02

Completion:

2030-06-01

Conditions

• HPV-Associated Oropharyngeal Squamous Cell Carcinoma
• HPV Positive Oropharyngeal Squamous Cell Carcinoma
• HPV-Mediated (P16-Positive) Oropharyngeal Carcinoma by AJCC V8 Stage
• HPV-Related Squamous Cell Carcinoma
• Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
• Pathologic Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
• Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
• Pathologic Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
• Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
• Pathologic Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
• HPV-Mediated (P16-Positive) Oropharyngeal Carcinoma by AJCC V8 Clinical Stage
• HPV-Mediated (P16-Positive) Oropharyngeal Carcinoma by AJCC V8 Pathologic Stage

Interventions

• DEVICE
• RADIATION
• DRUG

No Results Yet

NCT04892823 | RECRUITING

110 participants

Social Relationships and Accelerated Aging in Hematopoietic Cell Transplant Survivors

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-05

Start Date:

2021-05-18

Completion:

2027-07-16

Conditions

• Hematopoietic and Lymphoid Cell Neoplasm

Interventions

• PROCEDURE
• OTHER

No Results Yet

NCT04891640 | COMPLETED | PHASE4

164 participants

Biologic Abatement and Capturing Kids' Outcomes and Flare Frequency in Juvenile Spondyloarthritis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2021-11-11

Completion:

2026-06-01

Conditions

• Juvenile Spondyloarthritis

Interventions

• OTHER

No Results Yet

NCT04889911 | COMPLETED | NA

17 participants

Pilot RCT of Self-stigma Treatment for First Episode Psychosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2023-08-01

Completion:

2025-10-27

Conditions

• First Episode Psychosis
• Youth

Interventions

• OTHER
• BEHAVIORAL

No Results Yet

NCT04855305 | COMPLETED | PHASE2

47 participants

Optimizing and Standardizing 129Xe Gas Exchange MRI to Visualize Regional Therapy Response in Interstitial Lung Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2021-11-12

Completion:

2025-06-11

Conditions

• Interstitial Lung Diseases

Interventions

• DRUG

Results Available

NCT04851288 | COMPLETED | PHASE2

112 participants

Mitochondrial-targeted Antioxidant Supplementation for Improving Age-related Vascular Dysfunction in Humans

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2021-04-02

Completion:

2025-12-01

Conditions

• Aging

Interventions

• DIETARY_SUPPLEMENT

No Results Yet

NCT04840563 | COMPLETED | NA

10 participants

Surface Refractive Index Shift of Kalifilcon A Compared With Dailies Total1 and Precision1 Lenses

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2021-04-07

Completion:

2021-04-15

Conditions

• Contact Lens Wear

Interventions

• DEVICE

Results Available

NCT04833790 | COMPLETED | NA

2451 participants

What Drives Poor Care for Child Diarrhea: A Standardized Patient Experiment

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2022-05-05

Completion:

2022-12-31

Conditions

• Child Diarrhea

Interventions

• BEHAVIORAL

Results Available

NCT04827862 | COMPLETED | PHASE2

6 participants

RADVAX™ for Relapsed/Refractory Non-Hodgkin Lymphoma: A Phase II Trial of Pembrolizumab + Low Dose Radiotherapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2022-07-01

Completion:

2026-05-01

Conditions

• Non Hodgkin Lymphoma

Interventions

• DRUG

No Results Yet

NCT04810871 | SUSPENDED | NA

40 participants

Surgical Resection of Latent Brain Tumors Prior to Recurrence

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2021-05-06

Completion:

2028-03-01

Conditions

• Brain Neoplasm

Interventions

• PROCEDURE

No Results Yet

NCT04802759 | RECRUITING | PHASE1/PHASE2

316 participants

A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Participants With Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2021-06-22

Completion:

2029-05-30

Conditions

• Inoperable, Locally Advanced or Metastatic, ER-positive Breast Cancer

Interventions

• DRUG

No Results Yet

NCT04794075 | RECRUITING | NA

300 participants

Therapeutic Education and Nursing Support Program for Supportive Care, in Patients Treated With Hormone Therapy for Non-metastatic Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2021-08-09

Completion:

2028-08-31

Conditions

• Neoplasm of Breast

Interventions

• OTHER

No Results Yet

NCT04788836 | COMPLETED

61 participants

How Altered Gut-Brain-Axis Influences Food Choices: Part 2 (BrainFood)

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-05

Start Date:

2021-11-01

Completion:

2025-12-31

Conditions

• Food Preferences
• Obesity

Interventions

• OTHER

No Results Yet

NCT04743401 | COMPLETED | NA

54 participants

Feasibility of a Tele-game-based Exercise (Tele-exergame) Program to Prevent Deconditioning in Hospitalized COVID-19 Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2021-07-05

Completion:

2023-12-31

Conditions

• COVID 19
• Rehabilitation
• Inpatient
• Hospitalized

Interventions

• OTHER

Results Available

NCT04739189 | COMPLETED | NA

20 participants

Appetite Response to Exercise- Versus Energy Restriction-induced Energy Deficit in Adolescents With Obesity.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2021-08-28

Completion:

2021-10-03

Conditions

• Pediatric Obesity

Interventions

• BEHAVIORAL

No Results Yet

NCT04730479 | COMPLETED

330 participants

Echography to Predict Radial Artery Catheterization Failure (EPRAC)

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-05

Start Date:

2021-04-15

Completion:

2022-04-06

Conditions

• Cardiac and Aortic Surgery

No Results Yet

NCT04729933 | ACTIVE_NOT_RECRUITING | NA

16 participants

Implantation of a Permanent Interatrial Shunt to Reduce Left Atrial Filling Pressures Following MitraClip

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2021-03-11

Completion:

2025-01-03

Conditions

• Heart Failure
• Mitral Regurgitation

Interventions

• DEVICE

Results Available

NCT04713982 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

30 participants

Impact of Deutetrabenazine on Functional Speech and Gait Dynamics in Huntington Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2021-11-19

Completion:

2027-06-30

Conditions

• Huntington Disease

Interventions

• DRUG

No Results Yet

NCT04651504 | COMPLETED | NA

185903 participants

Rural Colon Cancer Screening Toolkit Intervention

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2020-12-02

Completion:

2024-12-31

Conditions

• Colon Cancer Screening

Interventions

• OTHER

Results Available

NCT04649086 | TERMINATED | NA

60 participants

Muscular Rehabilitation by Eccentric Exercise After Severe COVID-19 Infection

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2020-06-05

Completion:

2022-01-07

Conditions

• Covid19
• Sarcopenia
• Muscle Weakness

Interventions

• OTHER

No Results Yet

NCT04624581 | COMPLETED | NA

260 participants

FIbromyalgia anD GenetIcs Subgroups (FIDGIS)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2020-11-30

Completion:

2022-01-17

Conditions

• Fibromyalgia

Interventions

• DEVICE

No Results Yet

NCT04613596 | RECRUITING | PHASE2/PHASE3

626 participants

Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2020-12-02

Completion:

2028-10-31

Conditions

• Advanced Non-Small Cell Lung Cancer
• Metastatic Non-Small Cell Lung Cancer

Interventions

• DRUG

No Results Yet

NCT04589845 | ACTIVE_NOT_RECRUITING | PHASE2

920 participants

Tumor-agnostic Precision Immuno-oncology and Somatic Targeting Rational for You (TAPISTRY) Platform Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2021-01-18

Completion:

2032-09-25

Conditions

• Solid Tumors

Interventions

• DRUG

No Results Yet

NCT04577755 | ACTIVE_NOT_RECRUITING | PHASE2

45 participants

Pomalidomide Treatment in Patients With Kaposi Sarcoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2022-03-18

Completion:

2026-10-01

Conditions

• Skin Kaposi Sarcoma

Interventions

• PROCEDURE
• DRUG

No Results Yet

NCT04539366 | SUSPENDED | PHASE1

73 participants

Testing a New Immune Cell Therapy, GD2-Targeted Modified T-cells (GD2CART), in Children, Adolescents, and Young Adults With Relapsed/Refractory Osteosarcoma and Neuroblastoma, GD2-CAR PERSIST Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2022-01-25

Completion:

2040-12-31

Conditions

• Recurrent Childhood Neuroblastoma
• Recurrent Childhood Osteosarcoma
• Recurrent Neuroblastoma
• Recurrent Osteosarcoma
• Refractory Childhood Neuroblastoma
• Refractory Childhood Osteosarcoma
• Refractory Neuroblastoma
• Refractory Osteosarcoma

Interventions

• DRUG
• PROCEDURE
• BIOLOGICAL
• OTHER

No Results Yet

NCT04502758 | COMPLETED | NA

58 participants

Sequential Bilateral Accelerated Theta Burst Stimulation in Adolescents With Suicidal Ideation

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2022-04-04

Completion:

2026-06-30

Conditions

• Suicidal Ideation
• Major Depressive Disorder

Interventions

• DEVICE

No Results Yet

NCT04502407 | ACTIVE_NOT_RECRUITING | PHASE2

40 participants

Trial of De-Intensified Post-operative Chemoradiation Following Robotic Surgery for HPV-positive Oropharyngeal Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2021-02-16

Completion:

2026-12-15

Conditions

• HPV Positive Oropharyngeal Squamous Cell Carcinoma

Interventions

• RADIATION
• DRUG

No Results Yet

NCT04417283 | ACTIVE_NOT_RECRUITING

1000 participants

Project HOPE 1000: Health Outcomes Pregnancy Exposures

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-05

Start Date:

2018-11-21

Completion:

2024-11-22

Conditions

• Pregnant

No Results Yet

NCT04368858 | COMPLETED | NA

120 participants

Towards the Use of Instrumented Tests for Screening the Risk of Falling in Patients With Chronic Illness.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2020-08-28

Completion:

2022-11-16

Conditions

• Joint Osteoarthritis
• Atherosclerosis of the Distal Arteries, Without Gangrene
• Parkinson Disease
• Chronic Obstructive Pulmonary Disease, Unspecified
• Obesity, Unspecified

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT04356729 | ACTIVE_NOT_RECRUITING | PHASE2

30 participants

A Phase II Trial of PD-L1 Therapy Combined With Anti-VEGF Therapy in Unresectable or Metastatic Melanoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2020-08-06

Completion:

2026-06-01

Conditions

• Clinical Stage III Cutaneous Melanoma AJCC v8
• Stage IV Melanoma
• Unresectable Stage III Cutaneous Melanoma
• Unresectable Stage IV Cutaneous Melanoma

Interventions

• DRUG

No Results Yet

NCT04281199 | ACTIVE_NOT_RECRUITING | PHASE1

20 participants

TBI Using IMRT (VMAT or Tomotherapy) for the Prevention of Pul Toxicities in Patients Undergoing Donor SCT

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2020-02-28

Completion:

2027-06-24

Conditions

• Acute Leukemia
• Myelodysplastic Syndrome

Interventions

• PROCEDURE
• RADIATION

No Results Yet

NCT04264949 | COMPLETED | NA

120 participants

E-lombactifs: Evaluation of the Impact a Smartphone Application on Adherence an Exercise Program in Chronic Low Back Pain

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2020-03-09

Completion:

2023-12-18

Conditions

• Chronic Low Back Pain

Interventions

• OTHER

No Results Yet

NCT04247503 | ACTIVE_NOT_RECRUITING

419 participants

Cohort Study of Pancreatic Cancer Risk

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-05

Start Date:

2019-12-11

Completion:

2027-12-31

Conditions

• Familial Pancreatic Cancer

No Results Yet

NCT04242095 | RECRUITING

240 participants

Collection of Research Data and Samples From Patients Who Experience Immunotherapy Side Effects

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-05

Start Date:

2020-03-12

Completion:

2026-10-01

Conditions

• Malignancy

Interventions

• PROCEDURE
• OTHER

No Results Yet

NCT04216927 | RECRUITING | PHASE3

40 participants

NO During CPB in Neonates to Reduce Risk of AKI

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2023-01-10

Completion:

2027-06-30

Conditions

• AKI
• CHD - Congenital Heart Disease
• Surgery

Interventions

• DRUG

No Results Yet

NCT04181424 | ACTIVE_NOT_RECRUITING | NA

300 participants

Lowering the Impact of Food Insecurity in African American Adults With Type 2 Diabetes Mellitus (LIFT-DM)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2019-12-15

Completion:

2026-06-30

Conditions

• Type 2 Diabetes

Interventions

• BEHAVIORAL

No Results Yet

NCT04127006 | COMPLETED

103 participants

Rate of Progression in EYS Related Retinal Degeneration

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-05

Start Date:

2020-02-25

Completion:

2026-02-09

Conditions

• Retinitis Pigmentosa
• Eye Diseases

No Results Yet

NCT04121221 | COMPLETED | PHASE3

1016 participants

A Study to Asses Efficacy, Safety and Tolerability of Monthly Long-acting IM Injection of GA Depot in Subjects With RMS

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2019-09-19

Completion:

2023-06-13

Conditions

• Multiple Sclerosis, Relapsing-Remitting

Interventions

• DRUG
• OTHER

Results Available