Pomalidomide Treatment in Patients With Kaposi Sarcoma
NCT04577755 · Status: ACTIVE_NOT_RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 45
Last updated 2026-05-13
Summary
This phase II trial studies the effect of pomalidomide in treating patients with Kaposi sarcoma. Pomalidomide is a cancer fighting drug that stops the growth of blood vessels, stimulates the immune system, and may kill cancer cells.
Conditions
- Skin Kaposi Sarcoma
Interventions
- PROCEDURE
-
Biopsy Procedure
Undergo tissue biopsy
- PROCEDURE
-
Biospecimen Collection
Undergo blood sample collection
- PROCEDURE
-
Computed Tomography
Undergo CT
- DRUG
-
Given PO
- PROCEDURE
-
X-Ray Imaging
Undergo x-ray imaging
Sponsors & Collaborators
-
National Cancer Institute (NCI)
lead NIH
Principal Investigators
-
Samantha L Vogt · AIDS Malignancy Consortium
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2022-03-18
- Primary Completion
- 2026-10-01
- Completion
- 2026-10-01
- FDA Drug
- Yes
Countries
- United States
Study Locations
More Related Trials
-
Pomalidomide in Treating Patients With Kaposi Sarcoma and Human Immunodeficiency Virus Infection
NCT03601806 ·Status: COMPLETED ·Phase: PHASE2
-
Temozolomide in Treating Patients With Relapsed or Progressive Small Cell Lung Cancer
NCT00022711 ·Status: COMPLETED ·Phase: PHASE2
-
Lenalidomide in Treating Patients With AIDS-Associated Kaposi's Sarcoma
NCT01057121 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Temozolomide in Treating Patients With Metastatic Non-small Cell Lung Cancer
NCT00006877 ·Status: COMPLETED ·Phase: PHASE2
-
Temozolomide in Treating Patients With Stage IIIB, Stage IV, or Recurrent Non-small Cell Lung Cancer
NCT00005037 ·Status: COMPLETED ·Phase: PHASE2
-
Temozolomide in Patients With Progressive or Recurrent Non-small Cell Lung Cancer
NCT00003062 ·Status: COMPLETED ·Phase: PHASE2
-
Dolastatin 10 in Treating Patients With Recurrent or Metastatic Soft Tissue Sarcoma
NCT00003778 ·Status: COMPLETED ·Phase: PHASE2
-
Carboplatin, Paclitaxel, and Temozolomide for Patients With Metastatic Melanoma
NCT01009515 ·Status: TERMINATED ·Phase: PHASE2
-
Study of Induction PD-1 Blockade in Subjects With Locally Advanced Mismatch Repair Deficient Solid Tumors
NCT04165772 ·Status: RECRUITING ·Phase: PHASE2
-
Cixutumumab and Doxorubicin Hydrochloride in Treating Patients With Unresectable, Locally Advanced, or Metastatic Soft Tissue Sarcoma
NCT00720174 ·Status: COMPLETED ·Phase: PHASE1
-
Combination Chemotherapy Plus Thalidomide in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer
NCT00025285 ·Status: COMPLETED ·Phase: PHASE2
-
Cabozantinib-S-Malate in Treating Younger Patients With Recurrent, Refractory, or Newly Diagnosed Sarcomas, Wilms Tumor, or Other Rare Tumors
NCT02867592 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Localized High-Risk Soft Tissue Sarcomas Of The Extremities And Trunk Wall In Adults: An Integrating Approach Comprising Standard Vs Histotype-Tailored Neoadjuvant Chemotherapy
NCT01710176 ·Status: COMPLETED ·Phase: PHASE3
-
Depsipeptide (Romidepsin) in Treating Patients With Metastatic or Unresectable Soft Tissue Sarcoma
NCT00112463 ·Status: COMPLETED ·Phase: PHASE2
-
Temozolomide and Thalidomide in Treating Patients With Metastatic, Locally Advanced, or Unresectable Leiomyosarcoma
NCT00033709 ·Status: UNKNOWN ·Phase: PHASE2
-
Bortezomib in Treating Patients With Relapsed or Refractory AIDS-Related Kaposi Sarcoma
NCT01016730 ·Status: COMPLETED ·Phase: PHASE1
-
CP4071 in Treating Patients With Locally Advanced or Metastatic Soft Tissue Sarcoma
NCT00017446 ·Status: UNKNOWN ·Phase: PHASE2
-
Combination Chemotherapy and Surgery in Treating Patients With Newly Diagnosed Metastatic Osteosarcoma
NCT00003776 ·Status: COMPLETED ·Phase: PHASE2
-
Photodynamic Therapy in Treating Patients With Recurrent, Refractory, or Second Primary Head and Neck Cancer That Cannot Be Treated With Surgery or Radiation Therapy
NCT00003856 ·Status: UNKNOWN ·Phase: PHASE2
-
Cabozantinib S-malate in Treating Patients With Metastatic Pheochromocytomas or Paragangliomas That Cannot Be Removed by Surgery
NCT02302833 ·Status: COMPLETED ·Phase: PHASE2
-
Irinotecan and Carboplatin as Upfront Window Therapy in Treating Patients With Newly Diagnosed Intermediate-Risk or High-Risk Rhabdomyosarcoma
NCT00077285 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Dasatinib in Treating Patients With Stage III Melanoma That Cannot Be Removed By Surgery or Stage IV Melanoma
NCT00436605 ·Status: COMPLETED ·Phase: PHASE2
-
Paclitaxel and Carboplatin or Temozolomide in Treating Patients With Stage IV Melanoma
NCT00568451 ·Status: TERMINATED ·Phase: PHASE2
-
Cabozantinib With Pemetrexed in Advanced Non-small Cell Lung Cancer, Urothelial Cancer and Malignant Mesothelioma
NCT04173338 ·Status: TERMINATED ·Phase: PHASE1
-
Cabozantinib for Adults With Advanced Soft Tissue Sarcoma
NCT01755195 ·Status: COMPLETED ·Phase: PHASE2