Clinical Trials

NCT04613596 | RECRUITING | PHASE2/PHASE3

626 participants

Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2020-12-02

Completion:

2028-10-31

Conditions

• Advanced Non-Small Cell Lung Cancer
• Metastatic Non-Small Cell Lung Cancer

Interventions

• DRUG

No Results Yet

NCT04589845 | ACTIVE_NOT_RECRUITING | PHASE2

920 participants

Tumor-agnostic Precision Immuno-oncology and Somatic Targeting Rational for You (TAPISTRY) Platform Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2021-01-18

Completion:

2032-09-25

Conditions

• Solid Tumors

Interventions

• DRUG

No Results Yet

NCT04577755 | ACTIVE_NOT_RECRUITING | PHASE2

45 participants

Pomalidomide Treatment in Patients With Kaposi Sarcoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2022-03-18

Completion:

2026-10-01

Conditions

• Skin Kaposi Sarcoma

Interventions

• PROCEDURE
• DRUG

No Results Yet

NCT04539366 | SUSPENDED | PHASE1

73 participants

Testing a New Immune Cell Therapy, GD2-Targeted Modified T-cells (GD2CART), in Children, Adolescents, and Young Adults With Relapsed/Refractory Osteosarcoma and Neuroblastoma, GD2-CAR PERSIST Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2022-01-25

Completion:

2040-12-31

Conditions

• Recurrent Childhood Neuroblastoma
• Recurrent Childhood Osteosarcoma
• Recurrent Neuroblastoma
• Recurrent Osteosarcoma
• Refractory Childhood Neuroblastoma
• Refractory Childhood Osteosarcoma
• Refractory Neuroblastoma
• Refractory Osteosarcoma

Interventions

• DRUG
• PROCEDURE
• BIOLOGICAL
• OTHER

No Results Yet

NCT04502758 | COMPLETED | NA

58 participants

Sequential Bilateral Accelerated Theta Burst Stimulation in Adolescents With Suicidal Ideation

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2022-04-04

Completion:

2026-06-30

Conditions

• Suicidal Ideation
• Major Depressive Disorder

Interventions

• DEVICE

No Results Yet

NCT04502407 | ACTIVE_NOT_RECRUITING | PHASE2

40 participants

Trial of De-Intensified Post-operative Chemoradiation Following Robotic Surgery for HPV-positive Oropharyngeal Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2021-02-16

Completion:

2026-12-15

Conditions

• HPV Positive Oropharyngeal Squamous Cell Carcinoma

Interventions

• RADIATION
• DRUG

No Results Yet

NCT04417283 | ACTIVE_NOT_RECRUITING

1000 participants

Project HOPE 1000: Health Outcomes Pregnancy Exposures

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-05

Start Date:

2018-11-21

Completion:

2024-11-22

Conditions

• Pregnant

No Results Yet

NCT04368858 | COMPLETED | NA

120 participants

Towards the Use of Instrumented Tests for Screening the Risk of Falling in Patients With Chronic Illness.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2020-08-28

Completion:

2022-11-16

Conditions

• Joint Osteoarthritis
• Atherosclerosis of the Distal Arteries, Without Gangrene
• Parkinson Disease
• Chronic Obstructive Pulmonary Disease, Unspecified
• Obesity, Unspecified

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT04356729 | ACTIVE_NOT_RECRUITING | PHASE2

30 participants

A Phase II Trial of PD-L1 Therapy Combined With Anti-VEGF Therapy in Unresectable or Metastatic Melanoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2020-08-06

Completion:

2026-06-01

Conditions

• Clinical Stage III Cutaneous Melanoma AJCC v8
• Stage IV Melanoma
• Unresectable Stage III Cutaneous Melanoma
• Unresectable Stage IV Cutaneous Melanoma

Interventions

• DRUG

No Results Yet

NCT04281199 | ACTIVE_NOT_RECRUITING | PHASE1

20 participants

TBI Using IMRT (VMAT or Tomotherapy) for the Prevention of Pul Toxicities in Patients Undergoing Donor SCT

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2020-02-28

Completion:

2027-06-24

Conditions

• Acute Leukemia
• Myelodysplastic Syndrome

Interventions

• PROCEDURE
• RADIATION

No Results Yet

NCT04264949 | COMPLETED | NA

120 participants

E-lombactifs: Evaluation of the Impact a Smartphone Application on Adherence an Exercise Program in Chronic Low Back Pain

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2020-03-09

Completion:

2023-12-18

Conditions

• Chronic Low Back Pain

Interventions

• OTHER

No Results Yet

NCT04247503 | ACTIVE_NOT_RECRUITING

419 participants

Cohort Study of Pancreatic Cancer Risk

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-05

Start Date:

2019-12-11

Completion:

2027-12-31

Conditions

• Familial Pancreatic Cancer

No Results Yet

NCT04242095 | RECRUITING

240 participants

Collection of Research Data and Samples From Patients Who Experience Immunotherapy Side Effects

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-05

Start Date:

2020-03-12

Completion:

2026-10-01

Conditions

• Malignancy

Interventions

• PROCEDURE
• OTHER

No Results Yet

NCT04216927 | RECRUITING | PHASE3

40 participants

NO During CPB in Neonates to Reduce Risk of AKI

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2023-01-10

Completion:

2027-06-30

Conditions

• AKI
• CHD - Congenital Heart Disease
• Surgery

Interventions

• DRUG

No Results Yet

NCT04181424 | ACTIVE_NOT_RECRUITING | NA

300 participants

Lowering the Impact of Food Insecurity in African American Adults With Type 2 Diabetes Mellitus (LIFT-DM)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2019-12-15

Completion:

2026-06-30

Conditions

• Type 2 Diabetes

Interventions

• BEHAVIORAL

No Results Yet

NCT04127006 | COMPLETED

103 participants

Rate of Progression in EYS Related Retinal Degeneration

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-05

Start Date:

2020-02-25

Completion:

2026-02-09

Conditions

• Retinitis Pigmentosa
• Eye Diseases

No Results Yet

NCT04121221 | COMPLETED | PHASE3

1016 participants

A Study to Asses Efficacy, Safety and Tolerability of Monthly Long-acting IM Injection of GA Depot in Subjects With RMS

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2019-09-19

Completion:

2023-06-13

Conditions

• Multiple Sclerosis, Relapsing-Remitting

Interventions

• DRUG
• OTHER

Results Available

NCT04066036 | COMPLETED

999 participants

Population Effectiveness of Dolutegravir Implementation in Sub-Saharan Africa

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-05

Start Date:

2019-05-14

Completion:

2023-05-31

Conditions

• HIV-1-infection

Interventions

• OTHER

Results Available

NCT04030338 | ACTIVE_NOT_RECRUITING

58 participants

Prostate-Specific Membrane Antigen (PSMA) PET Scans in People Prostate Cancer

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-05

Start Date:

2019-07-19

Completion:

2027-07-31

Conditions

• Prostate Cancer
• Prostate Neoplasm
• Prostate Adenocarcinoma
• Prostate Cancer Metastatic
• Metastatic Prostate Cancer

Interventions

• DRUG
• DIAGNOSTIC_TEST

No Results Yet

NCT04017468 | COMPLETED | PHASE2

450 participants

Suprafascial Vancomycin Powder for Prevention of Surgical Site Infections After Instrumented Posterior Spinal Fusion

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2019-10-15

Completion:

2026-06-10

Conditions

• Surgical Site Infection

Interventions

• DRUG

No Results Yet

NCT03999710 | ACTIVE_NOT_RECRUITING | PHASE2

61 participants

Determining Whether Durvalumab in Combination With Radiation Therapy Can Prevent the Progression of Non-Small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2019-07-19

Completion:

2027-07-31

Conditions

• Non Small Cell Lung Cancer
• Lung Cancer
• Nsclc
• NSCLC Stage II
• NSCLC, Stage III

Interventions

• RADIATION
• DRUG

No Results Yet

NCT03996239 | ACTIVE_NOT_RECRUITING | NA

38 participants

Researching the Effect of Aerobic Exercise on Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2019-06-20

Completion:

2027-06-30

Conditions

• Cancer

Interventions

• BEHAVIORAL
• OTHER

No Results Yet

NCT03952559 | COMPLETED | PHASE3

516 participants

A Study of Baricitinib (LY3009104) in Children and Adolescents With Atopic Dermatitis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2019-05-24

Completion:

2022-04-24

Conditions

• Atopic Dermatitis

Interventions

• DRUG

Results Available

NCT03938610 | ACTIVE_NOT_RECRUITING

79 participants

Do Script Concordance Tests Correlate With Family Medicine Standardized Tests and Failing Rotation Grades?

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-05

Start Date:

2019-06-01

Completion:

2026-12-31

Conditions

• Knowledge, Attitudes, Practice

No Results Yet

NCT03887000 | COMPLETED | NA

75 participants

Magnesium, Stress and Fibromyalgia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2019-03-28

Completion:

2020-01-12

Conditions

• Fibromyalgia

Interventions

• OTHER

No Results Yet

NCT03847636 | COMPLETED | NA

33 participants

CryoBalloon Ablation for Treatment of Duodenal Adenomas

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2019-05-13

Completion:

2025-06-01

Conditions

• Duodenal Adenomas
• Familial Adenomatous Polyposis

Interventions

• DEVICE

Results Available

NCT03700203 | ACTIVE_NOT_RECRUITING

5340 participants

Cardiac Arrest Pursuit Trial With Unique Registration and Epidemiologic Surveillance

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-05

Start Date:

2017-09-07

Completion:

2026-03-31

Conditions

• Cardiac Arrest, Out-Of-Hospital

No Results Yet

NCT03604302 | ACTIVE_NOT_RECRUITING | NA

33 participants

Evaluation of Preoperative Functional Magnetic Resonance Imaging (fMRI) in Patients With Brain Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2018-08-01

Completion:

2027-07-31

Conditions

• Brain Tumor

Interventions

• DEVICE

No Results Yet

NCT03567538 | ACTIVE_NOT_RECRUITING

20000 participants

National Register Studies in Thoracic Surgery

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-05

Start Date:

2018-01-01

Completion:

2029-01-01

Conditions

• Lung Cancer
• Pulmonary Metastasis
• Surgery

Interventions

• PROCEDURE

No Results Yet

NCT03551392 | COMPLETED | NA

30 participants

Pilot Intervention With Near Infrared Stimulation

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2019-06-26

Completion:

2026-04-30

Conditions

• Aging

Interventions

• DEVICE

No Results Yet

NCT03503071 | WITHDRAWN

0 participants

Quality of Life After Cytoreductive Surgery and Intraperitoneal Chemotherapy

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-05

Start Date:

2018-10-01

Completion:

2020-12-31

Conditions

• Colorectal Cancer Metastatic

Interventions

• PROCEDURE

No Results Yet

NCT03500328 | ACTIVE_NOT_RECRUITING | NA

900 participants

Traditional Versus Early Aggressive Therapy for Multiple Sclerosis Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2018-05-02

Completion:

2026-07-31

Conditions

• Multiple Sclerosis, Relapsing-Remitting

Interventions

• OTHER

No Results Yet

NCT03487185 | ACTIVE_NOT_RECRUITING | NA

1500 participants

Continuous Positive Airway Pressure (CPAP) for Sleep Apnea in Pregnancy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2018-08-03

Completion:

2026-10-31

Conditions

• Obstructive Sleep Apnea of Adult
• Preeclampsia
• Obstetrical Complications

Interventions

• DEVICE
• OTHER

No Results Yet

NCT03459846 | ACTIVE_NOT_RECRUITING | PHASE2

154 participants

A Study of Durvalumab Alone and Durvalumab+Olaparib in Advanced, Platinum-Ineligible Bladder Cancer (BAYOU)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2018-03-16

Completion:

2020-10-15

Conditions

• Urinary Bladder Neoplasms

Interventions

• DRUG

Results Available

NCT03427736 | RECRUITING

551 participants

Anesthetics and Analgesics in Children

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-05

Start Date:

2018-12-13

Completion:

2027-08-30

Conditions

• Anesthesia
• Pain

Interventions

• DRUG

No Results Yet

NCT03409016 | ACTIVE_NOT_RECRUITING

69 participants

Biomarkers of Immune-Related Toxicity

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-05

Start Date:

2018-04-18

Completion:

2025-05-28

Conditions

• Cancer
• Metastatic Cancer

Interventions

• OTHER

No Results Yet

NCT03367169 | TERMINATED | NA

54 participants

Surgery of the Pilon Fractures

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2017-11-23

Completion:

2024-04-26

Conditions

• Pilon Fractures
• Fractures
• Bone
• Leg Injuries

Interventions

• PROCEDURE

No Results Yet

NCT03346135 | ACTIVE_NOT_RECRUITING | PHASE2

31 participants

Daratumumab After Stem Cell Transplant in Treating Patients With Multiple Myeloma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2019-07-17

Completion:

2027-05-17

Conditions

• Plasma Cell Myeloma
• Secondary Amyloidosis

Interventions

• PROCEDURE
• BIOLOGICAL
• OTHER
• DRUG

No Results Yet

NCT03327467 | AVAILABLE

Expanded Access Protocol: Umbilical Cord Blood Infusions for Children With Brain Injuries

Study Type:

EXPANDED_ACCESS

Last Updated:

2026-08-05

Conditions

• Cerebral Palsy
• Hydrocephalus
• Apraxia of Speech
• Hypoxia Ischemia, Cerebral
• Drowning; Anoxia

Interventions

• BIOLOGICAL

No Results Yet

NCT03242642 | RECRUITING | NA

1056 participants

Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2017-10-23

Completion:

2027-05-30

Conditions

• Mitral Valve Regurgitation

Interventions

• DEVICE

No Results Yet