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Continuous Positive Airway Pressure (CPAP) for Sleep Apnea in Pregnancy

NCT03487185 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 1500

Last updated 2026-04-06

No results posted yet for this study

Summary

A randomized controlled trial of 1,500 women to assess whether treatment of obstructive sleep apnea with continuous positive airway pressure (CPAP) in pregnancy will result in a reduction in the rate of hypertensive disorders of pregnancy.

Conditions

  • Obstructive Sleep Apnea of Adult
  • Preeclampsia
  • Obstetrical Complications

Interventions

DEVICE

Continuous Positive Airway Pressure

Autotitrating CPAP with weekly contact, incentives for compliance and initial sleep advice counseling

OTHER

Sleep Advice Control

Initial sleep advice counseling alone

Sponsors & Collaborators

  • Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

    collaborator NIH

  • National Heart, Lung, and Blood Institute (NHLBI)

    collaborator NIH

  • The George Washington University Biostatistics Center

    lead OTHER

Principal Investigators

  • Rebecca Clifton, PhD · The George Washington University Biostatistics Center

  • Monica Longo, MD · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

  • Francesca Facco, MD · Magee Women's Hospital of UPMC

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-08-03
Primary Completion
2026-12-31
Completion
2026-12-31
FDA Device
Yes

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03487185 on ClinicalTrials.gov