Clinical Trials

NCT04987060 | ACTIVE_NOT_RECRUITING | NA

24 participants

Intrastromal Fresh Human Corneal Lenticule Implantation Using Smile Surgery for Treatment of Irregular Corneal Astigmatism After Penetrating Keratoplasty (New Approach)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2017-03-01

Completion:

2021-03-01

Conditions

• Irregular Astigmatism

Interventions

• DEVICE

No Results Yet

NCT04978428 | COMPLETED | PHASE2

4 participants

Epidiolex in Obsessive Compulsive Disorder and Related Disorders

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2022-04-14

Completion:

2025-11-01

Conditions

• Obsessive-Compulsive Disorder
• Trichotillomania (Hair-Pulling Disorder)
• Tourette Syndrome
• Hoarding Disorder

Interventions

• DRUG

Results Available

NCT04974944 | TERMINATED | PHASE2

35 participants

First-line Treatment With Camrelizumab + Apatinib Versus Chemotherapy + Bevacizumab in Advanced Cervical Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2021-07-30

Completion:

2024-01-08

Conditions

• Stage IVB Cervical Cancer
• Recurrent Cervical Cancer
• Persistent Cervical Cancer

Interventions

• DRUG

No Results Yet

NCT04936321 | COMPLETED | NA

224 participants

Intervention for Sleep and Pain in Youth: A Randomized Controlled Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2021-10-01

Completion:

2026-03-12

Conditions

• Insomnia
• Migraine Disorders
• Headache Disorders

Interventions

• BEHAVIORAL

No Results Yet

NCT04850105 | ACTIVE_NOT_RECRUITING

202 participants

A Non-interventional Cohort Safety Study of Patients With hATTR-PN

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-29

Start Date:

2021-09-21

Completion:

2036-03-31

Conditions

• Hereditary Transthyretin Amyloidosis With Polyneuropthy

Interventions

• OTHER

No Results Yet

NCT04848740 | ENROLLING_BY_INVITATION | NA

100 participants

Human Fresh Corneal Lenticule Implantation Criteria in Progressive Corneal Disease Using Relex-Smile

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2018-02-01

Completion:

2027-02-01

Conditions

• Progressive Disease of Corneae

Interventions

• DEVICE

No Results Yet

NCT04797702 | TERMINATED | PHASE1/PHASE2

6 participants

Glumetinib Combined With Toripalimab in the Treatment of Relapsed or Metastatic Non-small Cell Lung Cancer.

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2021-04-21

Completion:

2022-11-07

Conditions

• Relapsed or Metastatic Non-small Cell Lung Cancer

Interventions

• COMBINATION_PRODUCT

No Results Yet

NCT04763902 | COMPLETED | NA

39 participants

Time Restricted Eating (TRE) Among Native Hawaiian/Pacific Islander Women at Risk for Endometrial Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2021-02-18

Completion:

2022-06-10

Conditions

• Endometrial Neoplasms

Interventions

• BEHAVIORAL

Results Available

NCT04753320 | NOT_YET_RECRUITING

85 participants

Remote Monitoring in Progressive Supranuclear Palsy (PSP)

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-29

Start Date:

2026-09-01

Completion:

2028-12-31

Conditions

• Progressive Supranuclear Palsy
• Parkinson Disease
• MSA - Multiple System Atrophy

No Results Yet

NCT04737252 | COMPLETED | NA

42 participants

Development and Initial Testing of a Couple-Based Intervention to Optimize Suicide and Self-Injury Treatment: COMPASS (Connecting, Overcoming, and Moving Past Suicide and Self-Injury)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2021-01-18

Completion:

2023-08-10

Conditions

• Self-injurious Thoughts and Behaviours
• Borderline Personality Disorder

Interventions

• BEHAVIORAL

No Results Yet

NCT04712643 | ACTIVE_NOT_RECRUITING | PHASE3

342 participants

A Study of TACE Combined With Atezolizumab Plus Bevacizumab or TACE Alone in Patients With Untreated Heaptocellular Carcionma

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2021-03-12

Completion:

2029-02-01

Conditions

• Hepatocellular Carcinoma

Interventions

• DRUG
• DEVICE

No Results Yet

NCT04712318 | ENROLLING_BY_INVITATION | NA

130 participants

Treatment of Residual Refraction Errors 6 Months After Trifocal IOL Implantation With Relex-Smile

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2016-06-01

Completion:

2018-06-01

Conditions

• Pseudophakia
• Myopia
• Hyperopia

Interventions

• PROCEDURE

No Results Yet

NCT04704999 | RECRUITING | PHASE4

820 participants

Southeast Asia Dose Optimization of Tafenoquine

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2024-07-22

Completion:

2027-10-04

Conditions

• Plasmodium Vivax Malaria

Interventions

• DRUG

No Results Yet

NCT04693663 | ENROLLING_BY_INVITATION | NA

20 participants

Treatment of Residual Myopic Refraction After 6 Months on Pseudophakic Patients Using Relex-Smile

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2017-06-01

Completion:

2018-06-01

Conditions

• Pseudophakia
• Myopia

Interventions

• PROCEDURE

No Results Yet

NCT04692012 | ACTIVE_NOT_RECRUITING | NA

34 participants

Treatment of Residual Hypermetropic Refraction on Pseudophakic Patients Using Allogenic Fresh Myopic Lenticule

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2018-04-01

Completion:

2020-04-01

Conditions

• Pseudophakia
• Hypermetropia
• Myopia

Interventions

• OTHER

No Results Yet

NCT04687475 | COMPLETED | NA

10 participants

Implementation of a Clinical Tool to Improve Waitlist Mortality in Patients With Cystic Fibrosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2020-04-20

Completion:

2026-02-01

Conditions

• Cystic Fibrosis
• Lung Transplant; Complications

Interventions

• OTHER

No Results Yet

NCT04642729 | ENROLLING_BY_INVITATION | NA

15 participants

Fresh Corneal Lenticule Implantation in Macular Corneal Distrophy With Relex Smile Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2019-06-01

Completion:

2020-06-01

Conditions

• Macular Corneal Dystrophy

Interventions

• PROCEDURE

No Results Yet

NCT04616144 | ACTIVE_NOT_RECRUITING | NA

55 participants

Fresh Corneal Lenticule Implantation in Hyperopic Patients With High Astigmatism

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2019-05-01

Completion:

2020-05-01

Conditions

• Hyperopia
• High Astigmatism

Interventions

• DEVICE

No Results Yet

NCT04597437 | RECRUITING | PHASE2

74 participants

Zanamivir Treatment of Vascular Permeability in Dengue (ZAP-DENGUE)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2024-03-15

Completion:

2027-08-31

Conditions

• Dengue Fever

Interventions

• DRUG
• OTHER

No Results Yet

NCT04594512 | ACTIVE_NOT_RECRUITING | NA

1 participants

Fresh Corneal Lenticule Implantation and Autologous Serum - Case Report

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2019-05-08

Completion:

2020-05-08

Conditions

• Keratoconus
• Keratoconus of Right Eye
• Keratoconus, Unstable, Right Eye

Interventions

• OTHER

No Results Yet

NCT04591587 | ENROLLING_BY_INVITATION | NA

40 participants

Corneal Lenticule Implantation in Keratoconus Disease With Relex Smile Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2018-01-01

Completion:

2019-01-01

Conditions

• Keratoconus

Interventions

• PROCEDURE

No Results Yet

NCT04545112 | ENROLLING_BY_INVITATION | NA

20 participants

Xeltis Coronary Artery Bypass Graft (XABG) First in Human (FIH)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2020-10-22

Completion:

2027-02-28

Conditions

• Multi Vessel Coronary Artery Disease

Interventions

• DEVICE

No Results Yet

NCT04543331 | COMPLETED

572 participants

Observational Study to Evaluate Fluid Resolution and Effectiveness in Patients Receiving Beovu in Neovascular Age-related Macular Degeneration and Visual Impairment Due to Diabetic Macular Edema

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-29

Start Date:

2020-11-05

Completion:

2025-11-17

Conditions

• Neovascular Age-related Macular Degeneration (nAMD)
• Diabetic Macular Edema (DME)

Interventions

• DRUG

No Results Yet

NCT04520698 | COMPLETED | NA

1322 participants

Utilizing Palliative Leaders In Facilities to Transform Care for Alzheimer's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2021-09-08

Completion:

2025-09-30

Conditions

• Alzheimer Disease

Interventions

• BEHAVIORAL

No Results Yet

NCT04512378 | COMPLETED | NA

6 participants

Group CBT for Intolerance of Uncertainty

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2021-02-01

Completion:

2026-06-30

Conditions

• Generalized Anxiety Disorder
• Intolerance of Uncertainty
• Anxiety

Interventions

• BEHAVIORAL

No Results Yet

NCT04485091 | COMPLETED | PHASE2

42 participants

TCA Peel and Photobiomodulation for Hand Rejuvenation

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2021-10-01

Completion:

2022-01-31

Conditions

• Skin Aging

Interventions

• COMBINATION_PRODUCT
• OTHER

No Results Yet

NCT04458831 | COMPLETED

583 participants

A Prospective, Non-interventional, Multinational, Observational Study With Isatuximab in Patients With Relapsed and/or Refractory Multiple Myeloma (RRMM)

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-29

Start Date:

2020-08-13

Completion:

2026-02-23

Conditions

• Plasma Cell Myeloma

Interventions

• DRUG

No Results Yet

NCT04450914 | COMPLETED | NA

112127 participants

Implementing Shared Decision Making (SDM) For Individualized CV Prevention (SDM4IP)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2021-05-10

Completion:

2024-12-31

Conditions

• Cardiovascular Risk
• Cardiovascular Prevention

Interventions

• BEHAVIORAL

Results Available

NCT04436068 | COMPLETED | NA

100 participants

Hyperfine Portable MRI in Hydrocephalus and Other Conditions Prompting Outpatient Brain Imaging

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2019-06-28

Completion:

2026-01-30

Conditions

• Hydrocephalus
• Neurological Disorder

Interventions

• DEVICE

No Results Yet

NCT04416412 | COMPLETED

124 participants

ICG Fluorescence Imaging in Open Fracture Trauma Patients

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-29

Start Date:

2020-10-01

Completion:

2026-07-01

Conditions

• Trauma Injury

Interventions

• OTHER

No Results Yet

NCT04411693 | COMPLETED | PHASE4

23 participants

Comparative Study of Dexamethasone Implant to Intravitreal Aflibercept in Subjects With Diabetic Macular Edema

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2020-04-10

Completion:

2025-05-14

Conditions

• Diabetic Macular Edema

Interventions

• DRUG

Results Available

NCT04386005 | COMPLETED | NA

50 participants

Continuous Glucose Monitoring in At-Risk Newborns

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2021-08-09

Completion:

2026-06-30

Conditions

• Neonatal Hypoglycemia

Interventions

• DEVICE

No Results Yet

NCT04375722 | RECRUITING | NA

50 participants

Transcranial Alternating Current Stimulation (tACS) in Aphasia

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2020-01-04

Completion:

2030-01-31

Conditions

• Aphasia
• Stroke

Interventions

• DEVICE

No Results Yet

NCT04371445 | RECRUITING | PHASE4

30 participants

Dextenza in the Post-op Management of Vitreoretinal Surgeries

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2020-06-01

Completion:

2027-12-01

Conditions

• Vitreoretinal Surgery
• Ocular Inflammation
• Post-operative Pain
• Post-Operative Inflammation

Interventions

• DRUG

No Results Yet

NCT04323774 | ACTIVE_NOT_RECRUITING | NA

115 participants

Intervention For Adolescents and Young Adults (AYAs) With Cancer Risk Syndromes

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2021-03-01

Completion:

2025-07-11

Conditions

• Cancer Risk Syndrome

Interventions

• BEHAVIORAL

No Results Yet

NCT04261712 | TERMINATED | PHASE2

43 participants

A Study to Evaluate the Long-Term Safety and Efficacy of Paltusotine for the Treatment of Acromegaly (ACROBAT Advance)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2020-01-29

Completion:

2026-06-30

Conditions

• Acromegaly

Interventions

• DRUG

No Results Yet

NCT04245085 | COMPLETED | PHASE2

95 participants

ABC-lung: Atezolizumab, Bevacizumab and Chemotherapy in EGFR-mutant Non-small Cell Lung Carcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2020-09-29

Completion:

2024-07-22

Conditions

• EGFRmutant Stage IIIB/C or IV Non-squamous NSCLC

Interventions

• DRUG

Results Available

NCT04201106 | TERMINATED | NA

16 participants

A Neuroimaging Study of Open-label Placebo in Depressed Adolescents

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2020-05-14

Completion:

2022-04-28

Conditions

• Depression

Interventions

• BEHAVIORAL

No Results Yet

NCT04198766 | RECRUITING | PHASE1/PHASE2

340 participants

Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2019-12-10

Completion:

2033-07-31

Conditions

• Solid Tumor
• Non-Small Cell Lung Cancer
• Head and Neck Cancer
• Melanoma
• Gastric Cancer
• Renal Cell Carcinoma
• Urothelial Carcinoma
• Resectable Non-Small-Cell Lung Cancer

Interventions

• DRUG

No Results Yet

NCT04113486 | RECRUITING

400 participants

Expression Levels of Nicotinamide Metabolism-related Protein (NMAP) in Newly Diagnosed Renal Cancer and Non-renal Cancer Populations

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-29

Start Date:

2019-10-01

Completion:

2029-01-30

Conditions

• Carcinoma, Renal Cell

Interventions

• OTHER

No Results Yet