Clinical Trials

NCT05645692 | ACTIVE_NOT_RECRUITING | PHASE2

204 participants

A Study Evaluating Different Immunotherapies (LAG-3 and PD-1 With or Without TIGIT, Compared to PD-L1 Alone) in Participants With Untreated Locally Advanced Metastatic Urothelial Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2023-04-13
Completion:: 2026-12-31

Conditions

Urothelial Cancer

Interventions

DRUG

No Results Yet

NCT05599789 | ACTIVE_NOT_RECRUITING | PHASE2

47 participants

Pembrolizumab in Combination With Plinabulin and Docetaxel For Metastatic NSCLC After ICIs (KeyPemls-004)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2023-02-01
Completion:: 2025-05-21

Conditions

Non Small Cell Lung Cancer Metastatic

Interventions

DRUG

No Results Yet

NCT05588323 | RECRUITING | PHASE1/PHASE2

24 participants

Safety and Pharmacokinetics Study of Naldemedine in Paediatric Participants Receiving Opioids

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2023-01-04
Completion:: 2028-06-15

Conditions

Opioid-Induced Constipation (OIC)

Interventions

DRUG

No Results Yet

NCT05574335 | TERMINATED | PHASE1/PHASE2

8 participants

Siplizumab in T1DM

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2023-05-18
Completion:: 2025-05-14

Conditions

Type 1 Diabetes Mellitus

Interventions

DRUG

Results Available

NCT05521321 | COMPLETED | NA

658 participants

Feasibility and Acceptability of the Cannabis Awareness and Prevention Toolkit

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2022-10-01
Completion:: 2025-05-16

Conditions

Cannabis Use

Interventions

BEHAVIORAL

Results Available

NCT05513742 | COMPLETED | PHASE2

49 participants

A Study of CTX-009 in Adult Patients With Metastatic Colorectal Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2022-12-08
Completion:: 2025-05-15

Conditions

Metastatic Colorectal Cancer
Colon Cancer
Rectal Cancer

Interventions

DRUG

Results Available

NCT05505942 | ACTIVE_NOT_RECRUITING | NA

222 participants

Physical Activity for PLWH and Unhealthy Drinking

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2023-02-22
Completion:: 2026-09-30

Conditions

HIV
Physical Inactivity
Unhealthy Alcohol Use

Interventions

BEHAVIORAL
OTHER

No Results Yet

NCT05503173 | ACTIVE_NOT_RECRUITING | NA

253 participants

Telehealth for Pain and Unhealthy Drinking Among PLWH

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2023-03-03
Completion:: 2026-12-31

Conditions

HIV
Chronic Pain
Unhealthy Alcohol Use

Interventions

BEHAVIORAL
OTHER

No Results Yet

NCT05498662 | ACTIVE_NOT_RECRUITING

60 participants

An Observational Study of the T3 Pro Dental Implant System

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-28
Start Date:: 2022-09-08
Completion:: 2027-12-30

Conditions

Tooth Loss

Interventions

DEVICE

No Results Yet

NCT05463224 | ACTIVE_NOT_RECRUITING | PHASE2

150 participants

Lazertinib for NSCLC Harboring Activating EGFR Mutations in TKI naïve Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2023-01-04
Completion:: 2026-12-01

Conditions

NSCLC

Interventions

DRUG

No Results Yet

NCT05454787 | RECRUITING

300 participants

Ondexxya for Intravenous Injection 200mg Drug Use Result Investigation (All Case Investigation)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-28
Start Date:: 2022-06-02
Completion:: 2026-10-31

Conditions

Life Threatening Bleeding
Factor Xa Inhibitor

No Results Yet

NCT05420233 | ACTIVE_NOT_RECRUITING | NA

533 participants

The CROCO Study: CROhn's Disease COhort Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2021-08-01
Completion:: 2030-07-31

Conditions

Crohn Disease

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05416853 | COMPLETED | NA

1200 participants

Radial Versus Femoral Access For Carotid Artery Stenting

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2022-07-04
Completion:: 2025-03-24

Conditions

Ischemic Stroke
Carotid Stenosis
Cerebral Revascularization
Carotid Artery Diseases

Interventions

PROCEDURE

No Results Yet

NCT05415072 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

66 participants

A Phase I/II Study of DYP688 in Patients With Metastatic Uveal Melanoma and Other GNAQ/11 Mutant Melanomas

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2022-07-04
Completion:: 2027-10-01

Conditions

Metastatic Uveal Melanoma

Interventions

DRUG

No Results Yet

NCT05397496 | ACTIVE_NOT_RECRUITING | PHASE1

61 participants

Study of PIT565 in Relapsed and/or Refractory B-cell Malignancies

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2022-10-03
Completion:: 2027-01-04

Conditions

B-cell Non-Hodgkin Lymphoma (B-NHL)
B-cell Acute Lymphoblastic Leukemia (B-ALL)

Interventions

BIOLOGICAL

No Results Yet

NCT05373823 | RECRUITING | NA

385 participants

MySmartSkin Online Skin Self-exam Intervention for Melanoma Survivors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2023-03-06
Completion:: 2026-12-31

Conditions

Melanoma

Interventions

OTHER

No Results Yet

NCT05368038 | ENROLLING_BY_INVITATION

100000 participants

ScreenPlus: A Comprehensive, Flexible, Multi-disorder Newborn Screening Program

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-28
Start Date:: 2021-05-10
Completion:: 2029-08-31

Conditions

Acid Sphingomyelinase Deficiency
Ceroid Lipofuscinosis, Neuronal, 2
Cerebrotendinous Xanthomatosis
Fabry Disease
GM1 Gangliosidosis
Gaucher Disease
Lysosomal Acid Lipase Deficiency
Metachromatic Leukodystrophy
Mucopolysaccharidosis II
Mucopolysaccharidosis III-B
Mucopolysaccharidosis IV A
Mucopolysaccharidosis VI
Mucopolysaccharidosis VII
Niemann-Pick Disease, Type C

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05362773 | ACTIVE_NOT_RECRUITING | PHASE1

130 participants

A Study of MGD024 in Patients With Relapsed or Refractory Hematologic Malignancies

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2022-07-13
Completion:: 2026-11-30

Conditions

Leukemia, Acute Myeloid
Myelodysplastic Syndromes
Classical Hodgkin Lymphoma
Leukemia, B-cell
Leukemia, Hairy Cell
Mastocytosis, Aggressive Systemic
Blastic Plasmacytoid Dendritic Cell Neoplasm
Chronic Myeloid Leukemia

Interventions

DRUG

No Results Yet

NCT05353452 | COMPLETED | NA

40 participants

Collaborative Care in Posttraumatic Epilepsy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2023-04-30
Completion:: 2026-05-19

Conditions

Epilepsy, Post-Traumatic

Interventions

BEHAVIORAL

No Results Yet

NCT05351359 | COMPLETED | NA

343 participants

mHealth Intervention to Increase Physical Activity in Prediabetes and Type 2 Diabetes

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2022-04-25
Completion:: 2025-05-08

Conditions

Type 2 Diabetes
PreDiabetes

Interventions

BEHAVIORAL

No Results Yet

NCT05343793 | COMPLETED | NA

70 participants

Stagewise Implementation-To-Target- Medications for Addiction Treatment (SITT-MAT)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2022-03-14
Completion:: 2026-06-30

Conditions

Addiction, Opioid

Interventions

OTHER

No Results Yet

NCT05341453 | COMPLETED | NA

21 participants

Equine-Assisted Physiotherapy for Spinal Muscular Atrophy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2022-04-22
Completion:: 2024-09-25

Conditions

Spinal Muscular Atrophy

Interventions

PROCEDURE

No Results Yet

NCT05307432 | ENROLLING_BY_INVITATION | NA

2814 participants

Safety Planning Intervention Telehealth Service Model in Emergency Departments

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2022-05-01
Completion:: 2027-01-31

Conditions

Suicide
Suicidal Ideation

Interventions

BEHAVIORAL

No Results Yet

NCT05283356 | RECRUITING | PHASE4

1206 participants

Single Antiplatelet Treatment With Ticagrelor or Aspirin After Transcatheter Aortic Valve Implantation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2022-01-21
Completion:: 2027-06-30

Conditions

Severe Aortic Valve Stenosis
Aortic Valve Stenosis
Transcatheter Aortic Valve Replacement (TAVR)
Transcatheter Aortic Valve Implantation (TAVI)

Interventions

DRUG

No Results Yet

NCT05282901 | COMPLETED | PHASE2

51 participants

Efficacy and Safety of Pembrolizumab in Combination With Lenvatinib in Metastatic Uveal MElanoma Patients (PLUME)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2022-07-07
Completion:: 2025-04-28

Conditions

Metastatic Uveal Melanoma

Interventions

DRUG

No Results Yet

NCT05263050 | RECRUITING | PHASE2

111 participants

Trial of an Alternative Cabozantinib Dosing Schedule in Metastatic Renal Cell Carcinoma and Neuroendocrine Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2022-01-21
Completion:: 2026-12-31

Conditions

Metastatic Renal Cell Carcinoma
Clear-cell Metastatic Renal Cell Carcinoma
Neuroendocrine Tumors
Carcinoid Tumor

Interventions

DRUG

No Results Yet

NCT05259449 | COMPLETED | NA

146 participants

Efficacy of Educational Nutrition and Exercise on the Regulation of Appetite Through Exosomes in Type 2 Diabetics

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2022-03-10
Completion:: 2025-12-10

Conditions

Diabetes Mellitus, Type 2

Interventions

BEHAVIORAL
OTHER

No Results Yet

NCT05238675 | COMPLETED | PHASE2

322 participants

A Study to Test Whether Different Doses of BI 1291583 Help People With Bronchiectasis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2022-04-28
Completion:: 2024-05-01

Conditions

Bronchiectasis

Interventions

DRUG

No Results Yet

NCT05227326 | RECRUITING | PHASE1

92 participants

AOH1996 for the Treatment of Refractory Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2022-08-12
Completion:: 2029-09-13

Conditions

Refractory Malignant Solid Neoplasm
Osteosarcoma
Leiomyosarcomas
Synovial Sarcomas
Ovarian Cancer
Non-Small Cell Lung Cancer
Pancreatic Cancer

Interventions

DRUG

No Results Yet

NCT05219799 | RECRUITING | EARLY_PHASE1

72 participants

Sex Disparities in Hypoxic Vasodilation and Impact of Obesity

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2023-03-14
Completion:: 2027-07-30

Conditions

Obesity
Vasodilation
Healthy

Interventions

DRUG

No Results Yet

NCT05198765 | ACTIVE_NOT_RECRUITING | NA

10120 participants

Weight Loss Clinical Decision Support

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2023-04-19
Completion:: 2025-10-31

Conditions

Diabetes Mellitus, Type 2
Obesity

Interventions

BEHAVIORAL

No Results Yet

NCT05189925 | RECRUITING | PHASE1

25 participants

NADPH Oxidase Correction in mRNA-transfected Granulocyte-enriched Cells in Chronic Granulomatous Disease (CGD)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2022-07-22
Completion:: 2027-07-01

Conditions

Chronic Granulomatous Disease
Infection

Interventions

BIOLOGICAL

No Results Yet

NCT05186740 | ACTIVE_NOT_RECRUITING | NA

221 participants

ProVee Urethral Expander System IDE Study (ProVIDE)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2022-06-09
Completion:: 2024-03-15

Conditions

BPH With Symptomatic Lower Urinary Tract Symptoms

Interventions

DEVICE
PROCEDURE

Results Available

NCT05141682 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

11 participants

Oral Azacitidine for the Treatment of Relapsed or Refractory T-cell Large Granular Lymphocytic Leukemia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2022-06-29
Completion:: 2026-02-19

Conditions

T-Cell Large Granular Lymphocyte Leukemia

Interventions

DRUG

No Results Yet

NCT05109468 | ACTIVE_NOT_RECRUITING

46 participants

Assessment of Patients' Quality of Sexual Life After Anal Cancer Treatment

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-28
Start Date:: 2021-06-06
Completion:: 2023-08-31

Conditions

Anal Cancer
Sexuality
Psychologic Stress
HPV
Anxiety

Interventions

OTHER

No Results Yet

NCT05062863 | COMPLETED

139 participants

An Observational Clinical Study of the T3 Dental Implant System

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-28
Start Date:: 2021-10-20
Completion:: 2026-03-03

Conditions

Edentulous Jaw

Interventions

DEVICE

No Results Yet

NCT05050942 | ACTIVE_NOT_RECRUITING | PHASE3

332 participants

A Trial to Assess Efficacy and Safety of Octreotide Subcutaneous Depot in Patients With GEP-NET

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2021-10-22
Completion:: 2026-11-30

Conditions

Gastro-enteropancreatic Neuroendocrine Tumor

Interventions

DRUG

No Results Yet

NCT05045482 | RECRUITING | PHASE1

30 participants

Hepatic Impairment With Cirrhosis Due to Cholestatic Liver Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2021-10-21
Completion:: 2026-07-31

Conditions

Hepatic Impairment
Cirrhosis
Cholestatic Liver Disease

Interventions

DRUG

No Results Yet

NCT05044546 | ACTIVE_NOT_RECRUITING | NA

26 participants

A Behavioral Activation Prenatal and Postpartum Intervention for Depressed Pregnant Smokers

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2021-10-19
Completion:: 2024-11-22

Conditions

Depression
Tobacco Use Disorder

Interventions

OTHER
BEHAVIORAL
PROCEDURE

Results Available

NCT05021835 | COMPLETED | PHASE3

6385 participants

ZEUS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Cardiovascular Disease, Chronic Kidney Disease and Inflammation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2021-08-30
Completion:: 2026-06-09

Conditions

Cardiovascular Risk
Chronic Kidney Disease
Inflammation

Interventions

DRUG

No Results Yet