Clinical Trials

NCT04227847 | RECRUITING | PHASE1

178 participants

A Safety Study of SEA-CD70 in Patients With Myeloid Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-22

Start Date:

2020-08-07

Completion:

2027-07-04

Conditions

• Myelodysplastic Syndrome
• Acute Myeloid Leukemia

Interventions

• DRUG

No Results Yet

NCT04210115 | COMPLETED | PHASE3

703 participants

Study of Pembrolizumab (MK-3475) Versus Placebo in Participants With Esophageal Carcinoma Who Are Receiving Chemotherapy and Radiation Therapy (MK-3475-975/KEYNOTE-975)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-22

Start Date:

2020-02-28

Completion:

2026-01-21

Conditions

• Esophageal Squamous Cell Carcinoma (ESCC)
• Gastroesophageal Junction Carcinoma (GEJC)
• Esophageal Adenocarcinoma (EAC)

Interventions

• BIOLOGICAL
• DRUG
• RADIATION

No Results Yet

NCT04166487 | ACTIVE_NOT_RECRUITING | PHASE2

40 participants

Plasma-Adapted First-Line Pembro In NSCLC

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-22

Start Date:

2020-01-13

Completion:

2025-06-01

Conditions

• NSCLC Stage IV
• Metastatic Non-Small Cell Lung Cancer

Interventions

• DRUG
• DIAGNOSTIC_TEST

No Results Yet

NCT04163432 | TERMINATED | PHASE2

43 participants

Staggered, Chemo-Immunotherapy With Durvalumab, MEDI4736 Pemetrexed & Carboplatin (PC) for Metastatic Non-Squamous NSCLC

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-22

Start Date:

2020-06-18

Completion:

2025-05-24

Conditions

• Non-Small Cell Lung Cancer Metastatic

Interventions

• DRUG

Results Available

NCT04158362 | ACTIVE_NOT_RECRUITING | PHASE3

180 participants

Endocrine Therapy With Abemaciclib or Chemotherapy as Initial Metastatic Treatment in ER+/HER2- Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-22

Start Date:

2020-06-11

Completion:

2025-04-30

Conditions

• Cancer Metastatic

Interventions

• DRUG

No Results Yet

NCT04147884 | ACTIVE_NOT_RECRUITING | NA

4 participants

A Feasibility Study of the Millipede Transcatheter Annuloplasty Ring System in Patients With Functional Mitral Regurgitation

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-22

Start Date:

2019-11-13

Completion:

2021-12-17

Conditions

• Mitral Regurgitation Functional
• Mitral Valve Disease
• Cardiovascular Diseases

Interventions

• DEVICE

No Results Yet

NCT04125797 | COMPLETED | NA

39 participants

Study on Adhesion Properties of Three Different Adhesives

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-22

Start Date:

2019-10-07

Completion:

2019-10-31

Conditions

• Healthy

Interventions

• OTHER

Results Available

NCT04114981 | ACTIVE_NOT_RECRUITING | PHASE3

242 participants

Single Fraction Stereotactic Radiosurgery Compared With Fractionated Stereotactic Radiosurgery in Treating Patients With Resected Metastatic Brain Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-22

Start Date:

2019-11-19

Completion:

2025-12-14

Conditions

• Metastatic Malignant Neoplasm in the Brain

Interventions

• RADIATION
• PROCEDURE
• OTHER

No Results Yet

NCT04081246 | COMPLETED | NA

30 participants

Transurethral Modified En Bloc Resection For Large Bladder Tumours.

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-22

Start Date:

2020-09-07

Completion:

2024-03-15

Conditions

• Bladder Cancer
• Bladder Neoplasm
• Bladder Tumor

Interventions

• DEVICE

No Results Yet

NCT04056312 | COMPLETED | NA

45 participants

Modified Story Memory Technique (mSMT) in Persons With TBI

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-22

Start Date:

2016-06-29

Completion:

2022-06-30

Conditions

• Traumatic Brain Injury

Interventions

• BEHAVIORAL

No Results Yet

NCT03990610 | ACTIVE_NOT_RECRUITING | NA

30 participants

An Investigational Surgical Procedure (Vascularized Lymph Node Transfer) in Reducing the Risk of Lymphedema in Patients With Breast Cancer Undergoing Breast Reconstruction

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-22

Start Date:

2019-05-24

Completion:

2028-04-30

Conditions

• Breast Carcinoma

Interventions

• PROCEDURE

No Results Yet

NCT03983681 | COMPLETED | NA

81 participants

Evaluation of a Theory-Driven Manualized Approach to Improving New Learning and Memory in MS

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-22

Start Date:

2019-09-26

Completion:

2025-12-08

Conditions

• Multiple Sclerosis

Interventions

• BEHAVIORAL

No Results Yet

NCT03973229 | COMPLETED | EARLY_PHASE1

127 participants

Neuroendocrine Risk for PTSD in Women

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-22

Start Date:

2019-11-11

Completion:

2025-04-30

Conditions

• PTSD
• Trauma

Interventions

• DRUG
• OTHER

Results Available

NCT03966872 | ACTIVE_NOT_RECRUITING | NA

601 participants

Comparative Effectiveness of IIMR Versus CDSMP

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-22

Start Date:

2019-09-02

Completion:

2026-07-15

Conditions

• Mental Illness
• Chronic Disease

Interventions

• BEHAVIORAL

No Results Yet

NCT03964363 | COMPLETED | NA

512 participants

Home-based Prehabilitation for Elderly Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-22

Start Date:

2019-05-29

Completion:

2024-09-15

Conditions

• Frail Elderly Syndrome

Interventions

• BEHAVIORAL

No Results Yet

NCT03924856 | COMPLETED | PHASE3

907 participants

Perioperative Pembrolizumab (MK-3475) Plus Neoadjuvant Chemotherapy Versus Perioperative Placebo Plus Neoadjuvant Chemotherapy for Cisplatin-eligible Muscle-invasive Bladder Cancer (MIBC) (MK-3475-866/KEYNOTE-866)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-22

Start Date:

2019-06-13

Completion:

2026-01-26

Conditions

• Bladder Cancer

Interventions

• DRUG
• PROCEDURE

No Results Yet

NCT03896581 | COMPLETED | PHASE3

400 participants

A Study to Evaluate the Efficacy and Safety of Bimekizumab in the Treatment of Subjects With Active Psoriatic Arthritis

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-22

Start Date:

2019-03-28

Completion:

2021-12-08

Conditions

• Psoriatic Arthritis

Interventions

• DRUG
• OTHER

Results Available

NCT03895203 | COMPLETED | PHASE3

852 participants

A Study to Test the Efficacy and Safety of Bimekizumab in the Treatment of Subjects With Active Psoriatic Arthritis

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-22

Start Date:

2019-04-03

Completion:

2021-08-17

Conditions

• Psoriatic Arthritis

Interventions

• DRUG
• OTHER

Results Available

NCT03849651 | ACTIVE_NOT_RECRUITING | PHASE2

69 participants

TCRαβ-depleted Progenitor Cell Graft With Additional Memory T-cell DLI, Plus Selected Use of Blinatumomab, in Naive T-cell Depleted Haploidentical Donor Hematopoietc Cell Transplantation for Hematologic Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-22

Start Date:

2019-01-31

Completion:

2024-08-07

Conditions

• Acute Lymphoblastic Leukemia (ALL)
• Acute Myeloid Leukemia (AML)
• Myelodysplastic Syndromes (MDS)
• NK-Cell Leukemia
• Hodgkin Lymphoma
• Non Hodgkin Lymphoma (NHL)
• Juvenile Myelomonocytic Leukemia (JMML)
• Chronic Myeloid Leukemia (CML)

Interventions

• DRUG
• BIOLOGICAL
• DEVICE

Results Available

NCT03822572 | ACTIVE_NOT_RECRUITING | NA

92 participants

ABCSG C08-Exercise II: Trial of Endurance Exercise Following Adjuvant Chemotherapy for Colorectal Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-22

Start Date:

2019-02-14

Completion:

2028-01-31

Conditions

• Colorectal Carcinoma

Interventions

• OTHER

No Results Yet

NCT03796884 | ACTIVE_NOT_RECRUITING | PHASE2

150 participants

Linaclotide in Treating Patients With Stages 0-3 Colorectal Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-22

Start Date:

2019-10-30

Completion:

2026-09-30

Conditions

• Colorectal Adenoma
• Stage 0 Colorectal Cancer AJCC v8
• Stage I Colorectal Cancer AJCC v8
• Stage II Colorectal Cancer AJCC v8
• Stage IIA Colorectal Cancer AJCC v8
• Stage IIB Colorectal Cancer AJCC v8
• Stage IIC Colorectal Cancer AJCC v8
• Stage III Colorectal Cancer AJCC v8
• Stage IIIA Colorectal Cancer AJCC v8
• Stage IIIB Colorectal Cancer AJCC v8
• Stage IIIC Colorectal Cancer AJCC v8

Interventions

• DRUG
• OTHER

No Results Yet

NCT03796767 | COMPLETED | PHASE2

20 participants

Salvage Oligometastasectomy and Radiation Therapy in Recurrent Prostate Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-22

Start Date:

2019-09-09

Completion:

2024-02-13

Conditions

• Recurrent Prostate Carcinoma
• Metastatic Malignant Neoplasm in the Bone
• Metastatic Malignant Neoplasm in the Lymph Nodes
• Oligometastasis
• Prostate Adenocarcinoma
• PSA Failure

Interventions

• RADIATION
• PROCEDURE
• OTHER

Results Available

NCT03786081 | TERMINATED | PHASE1/PHASE2

214 participants

Safety and Efficacy of Tisotumab Vedotin Monotherapy & in Combination With Other Cancer Agents in Subjects With Cervical Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-22

Start Date:

2019-02-27

Completion:

2026-03-19

Conditions

• Cervical Cancer

Interventions

• DRUG

No Results Yet

NCT03762018 | COMPLETED | PHASE3

400 participants

BEAT-meso: Bevacizumab and Atezolizumab in Malignant Pleural Mesothelioma

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-22

Start Date:

2019-04-30

Completion:

2023-09-01

Conditions

• Pleural Mesothelioma Malignant Advanced

Interventions

• DRUG

Results Available

NCT03729518 | COMPLETED | NA

150 participants

TORS De-Intensification Protocol Version 2.0: Dose and Volume Reduction in the Neck

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-22

Start Date:

2018-10-11

Completion:

2026-07-15

Conditions

• Oropharyngeal Cancer
• Squamous Cell Carcinoma
• Human Papilloma Virus

Interventions

• RADIATION

No Results Yet

NCT03687112 | COMPLETED

167191 participants

National Bank Alzheimer

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-22

Start Date:

2010-01-01

Completion:

2016-12-31

Conditions

• Alzheimer Disease

Interventions

• OTHER

No Results Yet

NCT03680781 | COMPLETED | NA

40 participants

Accelerated Theta Burst in Treatment-Resistant Depression: A Dose Finding and Biomarker Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-22

Start Date:

2018-04-13

Completion:

2024-12-02

Conditions

• Treatment Resistant Depression

Interventions

• DEVICE

Results Available

NCT03672331 | ACTIVE_NOT_RECRUITING | NA

53142 participants

My Personalized Breast Screening

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-22

Start Date:

2019-07-18

Completion:

2027-08-31

Conditions

• Breast Screening

Interventions

• OTHER

No Results Yet

NCT03653702 | NOT_YET_RECRUITING | PHASE1

70 participants

Radiation-Free Technique for Evaluating Renal Scarring (RAFTERS)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-22

Start Date:

2027-07-01

Completion:

2029-06-30

Conditions

• Vesico-Ureteral Reflux

Interventions

• DRUG

No Results Yet

NCT03564340 | RECRUITING | PHASE1/PHASE2

890 participants

Study of REGN4018 (Ubamatamab) Administered Alone or in Combination With Cemiplimab in Adult Patients With Recurrent Ovarian Cancer or Other Recurrent Mucin-16 Expressing (MUC16+) Cancers

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-22

Start Date:

2018-05-21

Completion:

2027-05-10

Conditions

• Recurrent Ovarian Cancer
• Recurrent Fallopian Tube Cancer
• Recurrent Primary Peritoneal Cancer
• Recurrent Endometrial Cancer
• Endometrial Cancer
• Low-grade Serous Ovarian Cancer

Interventions

• DRUG

No Results Yet

NCT03549754 | RECRUITING

35000 participants

iCaReMe Global Registry: Multinational Real-world Evidence in Cardiorenal and Metabolic Diseases

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-22

Start Date:

2018-02-17

Completion:

2030-12-31

Conditions

• Type 2 Diabetes
• Hypertension
• Chronic Kidney Disease
• Heart Failure

No Results Yet

NCT03546686 | ACTIVE_NOT_RECRUITING | PHASE2

51 participants

Peri-Operative Immune Checkpoint Inhibition and Cryoablation in Women With Triple-negative Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-22

Start Date:

2019-11-12

Completion:

2027-06-30

Conditions

• Breast Cancer

Interventions

• DRUG
• PROCEDURE

No Results Yet

NCT03533985 | RECRUITING | NA

200 participants

Effect of Music Therapy on Infants With Neonatal Abstinence Syndrome

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-22

Start Date:

2017-11-01

Completion:

2026-12-31

Conditions

• NAS

Interventions

• BEHAVIORAL
• OTHER

No Results Yet

NCT03485209 | ACTIVE_NOT_RECRUITING | PHASE2

350 participants

Efficacy and Safety Study of Tisotumab Vedotin for Patients With Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-22

Start Date:

2018-06-25

Completion:

2026-03-20

Conditions

• Colorectal Neoplasms
• Carcinoma, Non-Small-Cell Lung
• Exocrine Pancreatic Cancer
• Carcinoma, Squamous Cell of Head and Neck

Interventions

• DRUG

No Results Yet

NCT03465072 | SUSPENDED | NA

22 participants

Abnormal Vascular, Metabolic, and Neural Function During Exercise in Heart Failure With Preserved Ejection Fraction

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-22

Start Date:

2018-02-01

Completion:

2027-03-01

Conditions

• Heart Failure With Normal Ejection Fraction

Interventions

• OTHER

No Results Yet

NCT03413384 | COMPLETED | PHASE2

100 participants

To Assess the Efficacy and Safety of Ceftriaxone in Patients With Mild to Moderate Parkinson's Disease Dementia

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-22

Start Date:

2019-02-15

Completion:

2025-07-28

Conditions

• Parkinson's Disease Dementia

Interventions

• DRUG
• OTHER

No Results Yet

NCT03363464 | COMPLETED

230000 participants

Comparative Effectiveness of Empagliflozin in the US

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-22

Start Date:

2017-10-16

Completion:

2026-07-09

Conditions

• Diabetes Mellitus, Type 2

Interventions

• DRUG

No Results Yet

NCT03324698 | ACTIVE_NOT_RECRUITING

4000 participants

The Natural History of Chronic Pancreatitis

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-22

Start Date:

2000-01-01

Completion:

2026-12-31

Conditions

• Chronic Pancreatitis
• Complication
• Risk Factors

No Results Yet

NCT03282344 | ACTIVE_NOT_RECRUITING | PHASE2

88 participants

A Study of NKTR-214 in Combination With Nivolumab in Patients With Metastatic and/or Locally Advanced Sarcoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-22

Start Date:

2017-09-12

Completion:

2027-09-30

Conditions

• SARCOMA

Interventions

• DRUG

No Results Yet

NCT03273023 | COMPLETED

2059 participants

PROMUS PREMIER™ China Post-Approval Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-22

Start Date:

2018-01-11

Completion:

2020-12-28

Conditions

• Coronary Artery Disease

Interventions

• DEVICE

Results Available