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Clinical Trials

NCT03093909 | RECRUITING | PHASE1
44 participants

Study of Aerosol Gemcitabine in Patients With Solid Tumors and Pulmonary Metastases

Study Type:
INTERVENTIONAL
Last Updated:
2026-07-15
Start Date:
2017-11-22
Completion:
2027-11-30
Conditions
  • Malignant Neoplasm of Bone and Articular Cartilage
  • Malignant Neoplasms of Female Genital Organs
  • Malignant Neoplasms of Independent (Primary) Multiple Sites
  • Malignant Neoplasms of Lip Oral Cavity and Pharynx
  • Malignant Neoplasm of Male Genital Organs
  • Malignant Neoplasms of Mesothelial and Soft Tissue
  • Malignant Neoplasm of Respiratory and Intrathoracic Organ Carcinoma
  • Malignant Neoplasms of Thyroid and Other Endocrine Glands
  • Malignant Neoplasms of Urinary Tract
  • Melanoma and Other Malignant Neoplasms of Skin
Interventions
  • DRUG
No Results Yet
NCT02912312 | ACTIVE_NOT_RECRUITING | PHASE2
805 participants

Hypofractionated vs. Conventional Regional Nodal Radiation Therapy for Patients With Invasive Breast Cancer

Study Type:
INTERVENTIONAL
Last Updated:
2026-07-15
Start Date:
2017-02-23
Completion:
2030-02-28
Conditions
  • Invasive Breast Carcinoma
  • Stage I Breast Cancer AJCC v7
  • Stage IA Breast Cancer AJCC v7
  • Stage IB Breast Cancer AJCC v7
  • Stage II Breast Cancer AJCC v6 and v7
  • Stage IIA Breast Cancer AJCC v6 and v7
  • Stage IIB Breast Cancer AJCC v6 and v7
  • Stage IIIA Breast Cancer AJCC v7
  • Stage IIIC Breast Cancer AJCC v7
Interventions
  • RADIATION
  • OTHER
No Results Yet
NCT02760849 | ACTIVE_NOT_RECRUITING | NA
374 participants

Surgery in Preventing Ovarian Cancer in Patients With Genetic Mutations

Study Type:
INTERVENTIONAL
Last Updated:
2026-07-15
Start Date:
2016-05-02
Completion:
2041-05-31
Conditions
  • Deleterious BARD1 Gene Mutation
  • Deleterious BRCA1 Gene Mutation
  • Deleterious BRCA2 Gene Mutation
  • Deleterious BRIP1 Gene Mutation
  • Deleterious EPCAM Gene Mutation
  • Deleterious MLH1 Gene Mutation
  • Deleterious MSH2 Gene Mutation
  • Deleterious MSH6 Gene Mutation
  • Deleterious PALB2 Gene Mutation
  • Deleterious PMS2 Gene Mutation
  • Deleterious RAD51C Gene Mutation
  • Deleterious RAD51D Gene Mutation
  • Hereditary Breast and Ovarian Cancer Syndrome
  • Premenopausal
Interventions
  • OTHER
  • PROCEDURE
No Results Yet
NCT02530034 | ACTIVE_NOT_RECRUITING | PHASE1
72 participants

Hu8F4 in Treating Patients With Advanced Hematologic Malignancies

Study Type:
INTERVENTIONAL
Last Updated:
2026-07-15
Start Date:
2019-01-31
Completion:
2027-01-01
Conditions
  • Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome
  • Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive
  • Hematopoietic and Lymphoid Cell Neoplasm
  • High Risk Myelodysplastic Syndrome
  • Myelodysplastic Syndrome With Excess Blasts-1
  • Myelodysplastic Syndrome With Excess Blasts-2
  • Myelofibrosis
  • Recurrent Acute Myeloid Leukemia
  • Recurrent Chronic Myelomonocytic Leukemia
  • Refractory Chronic Myelomonocytic Leukemia
  • Secondary Acute Myeloid Leukemia
Interventions
  • DRUG
  • OTHER
No Results Yet
NCT02494700 | ACTIVE_NOT_RECRUITING | PHASE2
50 participants

Ultra Low Dose Orbital Radiation Therapy in Treating Patients With Stage I-IV Indolent B-cell Lymphoma or Mantle Cell Lymphoma

Study Type:
INTERVENTIONAL
Last Updated:
2026-07-15
Start Date:
2015-07-06
Completion:
2027-06-30
Conditions
  • Ann Arbor Stage I B-Cell Non-Hodgkin Lymphoma
  • Ann Arbor Stage I Grade 1 Follicular Lymphoma
  • Ann Arbor Stage I Grade 2 Follicular Lymphoma
  • Ann Arbor Stage I Indolent Adult Non-Hodgkin Lymphoma
  • Ann Arbor Stage I Mantle Cell Lymphoma
  • Ann Arbor Stage II B-Cell Non-Hodgkin Lymphoma
  • Ann Arbor Stage II Grade 1 Follicular Lymphoma
  • Ann Arbor Stage II Grade 2 Follicular Lymphoma
  • Ann Arbor Stage II Indolent Adult Non-Hodgkin Lymphoma
  • Ann Arbor Stage II Mantle Cell Lymphoma
  • Ann Arbor Stage III B-Cell Non-Hodgkin Lymphoma
  • Ann Arbor Stage III Grade 1 Follicular Lymphoma
  • Ann Arbor Stage III Grade 2 Follicular Lymphoma
  • Ann Arbor Stage III Indolent Adult Non-Hodgkin Lymphoma
  • Ann Arbor Stage III Mantle Cell Lymphoma
  • Ann Arbor Stage IV B-Cell Non-Hodgkin Lymphoma
  • Ann Arbor Stage IV Grade 1 Follicular Lymphoma
  • Ann Arbor Stage IV Grade 2 Follicular Lymphoma
  • Ann Arbor Stage IV Indolent Adult Non-Hodgkin Lymphoma
  • Ann Arbor Stage IV Mantle Cell Lymphoma
  • Ocular Adnexal Lymphoma
  • Ocular Adnexal Mucosa-Associated Lymphoid Tissue Lymphoma
  • Orbit Lymphoma
Interventions
  • RADIATION
  • DRUG
No Results Yet
NCT02411656 | ACTIVE_NOT_RECRUITING | PHASE2
71 participants

Pembrolizumab in Treating Patients With Stage IV Metastatic or Recurrent Inflammatory Breast Cancer or Triple-Negative Breast Cancer Who Have Achieved Clinical Response or Stable Disease to Prior Chemotherapy

Study Type:
INTERVENTIONAL
Last Updated:
2026-07-15
Start Date:
2015-06-11
Completion:
2024-06-15
Conditions
  • Edema
  • Erythema
  • Estrogen Receptor Negative
  • HER2/Neu Negative
  • Peau d'Orange
  • Progesterone Receptor Negative
  • Recurrent Inflammatory Breast Carcinoma
  • Stage IV Inflammatory Breast Carcinoma
  • Triple-Negative Breast Carcinoma
Interventions
  • OTHER
  • BIOLOGICAL
Results Available
NCT02276443 | ACTIVE_NOT_RECRUITING | NA
798 participants

Molecular Testing and Imaging in Improving Response in Patients With Stage I-III Triple-Negative Breast Cancer Receiving Chemotherapy MDACC Breast Moonshot Initiative

Study Type:
INTERVENTIONAL
Last Updated:
2026-07-15
Start Date:
2015-11-09
Completion:
2026-11-30
Conditions
  • Invasive Breast Carcinoma
  • Stage I Breast Cancer AJCC v7
  • Stage IA Breast Cancer AJCC v7
  • Stage IB Breast Cancer AJCC v7
  • Stage II Breast Cancer AJCC v6 and v7
  • Stage IIA Breast Cancer AJCC v6 and v7
  • Stage IIB Breast Cancer AJCC v6 and v7
  • Stage III Breast Cancer AJCC v7
  • Stage IIIA Breast Cancer AJCC v7
  • Stage IIIB Breast Cancer AJCC v7
  • Stage IIIC Breast Cancer AJCC v7
  • Triple-Negative Breast Carcinoma
Interventions
  • DRUG
  • OTHER
  • PROCEDURE
No Results Yet
NCT01371630 | RECRUITING | PHASE1/PHASE2
276 participants

Inotuzumab Ozogamicin and Combination Chemotherapy in Treating Patients With Acute Lymphoblastic Leukemia

Study Type:
INTERVENTIONAL
Last Updated:
2026-07-15
Start Date:
2011-08-26
Completion:
2027-12-25
Conditions
  • B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1
  • B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative
  • Burkitt-Like Lymphoma With 11q Aberration
  • High Grade B-Cell Lymphoma With MYC and BCL2 and/or BCL6 Rearrangements
  • High Grade B-Cell Lymphoma, Not Otherwise Specified
  • Recurrent B Acute Lymphoblastic Leukemia
  • Recurrent Burkitt Lymphoma
  • Refractory B Acute Lymphoblastic Leukemia
  • Refractory Burkitt Lymphoma
Interventions
  • BIOLOGICAL
  • DRUG
  • OTHER
No Results Yet
NCT01365169 | RECRUITING | NA
590 participants

Association Between Health Care Provider (HCP)-Assessed ECOG Performance Status (PS) and Overall Survival, and Objectively Measure of Physical Activity (PA) Levels in Advance-cancer Patients"

Study Type:
INTERVENTIONAL
Last Updated:
2026-07-15
Start Date:
2011-05-25
Completion:
2027-06-30
Conditions
  • Malignant Head and Neck Neoplasm
  • Malignant Neoplasm
  • Metastatic Malignant Neoplasm in the Neck
  • Metastatic Malignant Neoplasm in the Uterine Cervix
  • Pancreatic Adenocarcinoma
  • Pancreatic Neuroendocrine Carcinoma
  • Recurrent Colorectal Carcinoma
  • Stage I Colorectal Cancer AJCC v6 and v7
  • Stage I Hypopharyngeal Carcinoma AJCC v7
  • Stage I Major Salivary Gland Cancer AJCC v7
  • Stage I Nasopharyngeal Carcinoma AJCC v7
  • Stage I Oral Cavity Cancer AJCC v6 and v7
  • Stage I Oropharyngeal Carcinoma AJCC v6 and v7
  • Stage II Colorectal Cancer AJCC v7
  • Stage II Hypopharyngeal Carcinoma AJCC v6 and v7
  • Stage II Major Salivary Gland Cancer AJCC v7
  • Stage II Nasopharyngeal Carcinoma AJCC v7
  • Stage II Oral Cavity Cancer AJCC v6 and v7
  • Stage II Oropharyngeal Carcinoma AJCC v6 and v7
  • Stage IIA Colorectal Cancer AJCC v7
  • Stage IIB Colorectal Cancer AJCC v7
  • Stage IIC Colorectal Cancer AJCC v7
  • Stage III Colorectal Cancer AJCC v7
  • Stage III Hypopharyngeal Carcinoma AJCC v7
  • Stage III Laryngeal Cancer AJCC v6 and v7
  • Stage III Major Salivary Gland Cancer AJCC v7
  • Stage III Nasopharyngeal Carcinoma AJCC v7
  • Stage III Oral Cavity Cancer AJCC v6 and v7
  • Stage III Oropharyngeal Carcinoma AJCC v7
  • Stage IIIA Colorectal Cancer AJCC v7
  • Stage IIIB Colorectal Cancer AJCC v7
  • Stage IIIC Colorectal Cancer AJCC v7
  • Stage IV Colorectal Cancer AJCC v7
  • Stage IVA Colorectal Cancer AJCC v7
  • Stage IVA Hypopharyngeal Carcinoma AJCC v7
  • Stage IVA Laryngeal Cancer AJCC v7
  • Stage IVA Major Salivary Gland Cancer AJCC v7
  • Stage IVA Nasopharyngeal Carcinoma AJCC v7
  • Stage IVA Oral Cavity Cancer AJCC v6 and v7
  • Stage IVA Oropharyngeal Carcinoma AJCC v7
  • Stage IVB Colorectal Cancer AJCC v7
  • Stage IVB Hypopharyngeal Carcinoma AJCC v7
  • Stage IVB Laryngeal Cancer AJCC v7
  • Stage IVB Major Salivary Gland Cancer AJCC v7
  • Stage IVB Nasopharyngeal Carcinoma AJCC v7
  • Stage IVB Oral Cavity Cancer AJCC v6 and v7
  • Stage IVB Oropharyngeal Carcinoma AJCC v7
  • Metastatic or Locally Unresectable Solid Tumor
Interventions
  • OTHER
  • BEHAVIORAL
No Results Yet
NCT07703670 | RECRUITING | NA
160 participants

MicroRNAs as Biomarkers in First Episode Schizophrenia

Study Type:
INTERVENTIONAL
Last Updated:
2026-07-14
Start Date:
2026-07-01
Completion:
2031-05-31
Conditions
  • Schizophrenia Disorder
  • Schizophreniform Disorder
  • Schizoaffective Disorder
  • Psychosis Not Otherwise Specified (NOS)
Interventions
  • DIAGNOSTIC_TEST
  • GENETIC
No Results Yet
NCT07703644 | NOT_YET_RECRUITING
60 participants

Ceftazidime-Avibactam PK/PD and Resistance in Hematology Patients

Study Type:
OBSERVATIONAL
Last Updated:
2026-07-14
Start Date:
2026-07-09
Completion:
2027-07-09
Conditions
  • Hematologic Neoplasms
  • Gram-Negative Bacterial Infections
  • Pseudomonas Aeruginosa Infection
  • Klebsiella Pneumoniae Infections
  • Drug Resistance, Bacterial
Interventions
  • DRUG
  • PROCEDURE
No Results Yet
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