MedTrace Logo

Effects of Monday-Thursday Sunnah Fasting on Short-Chain Fatty Acids, GLP-1, Satiety, and Nutritional Status in Obese Males

NCT07703865 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 74

Last updated 2026-07-14

No results posted yet for this study

Summary

This quasi-experimental study investigated the effects of 8 weeks of Monday-Thursday Sunnah fasting on fecal short-chain fatty acids (SCFA), fasting total GLP-1, appetite regulation (hunger and satiety area under the curve), dietary intake, and body composition in obese adult males in Indonesia.

Monday-Thursday Sunnah fasting is a twice-weekly Islamic religious practice involving complete abstention from food and water (dry fasting) from dawn (approximately 04:30) to sunset (approximately 18:00), approximately 13 hours per day, practiced by millions of Indonesian Muslims. Unlike conventional intermittent fasting protocols, Sunnah fasting is motivated by religious observance, which may enhance adherence.

Seventy-four obese adult males were enrolled (intervention n=38, control n=36). The intervention group performed 16 fasting days over 8 weeks without any caloric restriction outside fasting hours. Fecal SCFA were measured by GC-MS; fasting total GLP-1 by ELISA; appetite by Visual Analogue Scale (VAS); dietary intake by 24-hour recall; and body composition by bioelectrical impedance analysis.

Primary analyses used linear mixed models (LMM) controlling for baseline differences arising from the sequential allocation design.

Conditions

  • Obesity & Overweight
  • Gut -Microbiota

Interventions

BEHAVIORAL

Monday-Thursday Sunnah Dry Fasting

Twice-weekly daytime dry fasting (no food or water) from approximately 04:30 to 18:00 (\~13 hours), performed every Monday and Thursday for 8 consecutive weeks. This practice is based on Islamic religious Sunnah. No caloric restriction was imposed outside fasting hours.

Sponsors & Collaborators

  • University of Muhammadiyah Jakarta

    lead OTHER

Principal Investigators

  • Tirta P Sari, Medical Doctor · University of Muhammadiyah Jakarta

Study Design

Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
19 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-09-15
Primary Completion
2025-12-11
Completion
2025-12-29

Countries

  • Indonesia

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07703865 on ClinicalTrials.gov