Clinical Trials

NCT05532657 | ACTIVE_NOT_RECRUITING | PHASE3

629 participants

ACHIEVE Brain Health Follow-Up Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2023-01-12
Completion:: 2026-06-30

Conditions

Aging
Cognitive Decline
Mild Cognitive Impairment
Dementia
Hearing Loss

Interventions

OTHER

No Results Yet

NCT05524987 | ACTIVE_NOT_RECRUITING | NA

1068 participants

Addressing HyperteNsion and Diabetes Through Community-Engaged Systems in Puno, Peru (ANDES Study)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2023-03-20
Completion:: 2026-06-30

Conditions

Hypertension
Diabetes

Interventions

BEHAVIORAL

No Results Yet

NCT05522075 | RECRUITING | NA

55 participants

Reducing Blood Pressure in Mid-life Adult Binge Drinkers

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2022-11-21
Completion:: 2026-12-31

Conditions

Alcohol Drinking
Binge Drinking
Blood Pressure
Alcohol Abstinence
Aging
Lifestyle Factors
Vasodilation
Behavioral Problem

Interventions

BEHAVIORAL

No Results Yet

NCT05519644 | ACTIVE_NOT_RECRUITING | NA

60 participants

Strategies to Augment Ketosis: Ketone Conferred Resiliency Against Sleep Restriction

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2023-06-20
Completion:: 2026-09-30

Conditions

Sleep Deprivation

Interventions

OTHER
BEHAVIORAL
BIOLOGICAL
DIETARY_SUPPLEMENT

No Results Yet

NCT05507632 | ACTIVE_NOT_RECRUITING | PHASE2

48 participants

Donafenib Plus Sintilimab in Combination With TACE in Patients With Unresectable Hepatocellular Carcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2022-08-18
Completion:: 2026-03-26

Conditions

Unresectable Hepatocellular Carcinoma

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT05499897 | COMPLETED | NA

34 participants

Interscalene Brachial Plexus Block and Early Wound-Related Symptoms After Open Rotator Cuff Repair

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2022-06-01
Completion:: 2023-01-01

Conditions

Rotator Cuff Tear
Shoulder Surgery
Postoperative Recovery

Interventions

PROCEDURE

No Results Yet

NCT05496348 | RECRUITING

400 participants

Study of Oral Upadacitinib to Assess Change in Disease Activity in Adult Participants With Ulcerative Colitis

Study Type:: OBSERVATIONAL
Last Updated:: 2026-06-01
Start Date:: 2022-10-20
Completion:: 2027-08-31

Conditions

Ulcerative Colitis

No Results Yet

NCT05473429 | RECRUITING | NA

215 participants

Characterization of Nociception Phenotype in Individuals With Intellectual Disability

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2026-03-27
Completion:: 2026-10-06

Conditions

Intellectual Disability

Interventions

DEVICE

No Results Yet

NCT05470491 | RECRUITING | PHASE1/PHASE2

265 participants

Trial of Allogeneic Reduced-Intensity, HLA-Haploidentical Allogeneic Hematopoietic Cell Bone Marrow Transplantation Followed by Graft-versus-Host-Disease (GVHD) Prophylaxis With Cyclophosphamide, Bortezomib and Maraviroc for Hematologic Malignancies ...

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2023-01-26
Completion:: 2026-07-30

Conditions

HIV
Hematologic Malignancies

Interventions

DRUG
PROCEDURE

No Results Yet

NCT05469360 | ACTIVE_NOT_RECRUITING | PHASE1

38 participants

Study of Safety, Tolerability, Pharmacodynamics and Pharmacokinetics of NIO752 in Early Alzheimer's Disease Participants

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2023-02-23
Completion:: 2026-07-30

Conditions

Alzheimer Disease
Mild Cognitive Impairment

Interventions

DRUG

No Results Yet

NCT05469321 | TERMINATED

20 participants

Neurological Impairment in a Young Population Exposed to Recreational Nitrous Oxide

Study Type:: OBSERVATIONAL
Last Updated:: 2026-06-01
Start Date:: 2022-08-22
Completion:: 2025-05-03

Conditions

Neuropathy

Interventions

OTHER

No Results Yet

NCT05452070 | COMPLETED | PHASE3

171 participants

A Study to Assess Adverse Events and Change in Disease Activity of HArmonyCa Lidocaine Injectable Gel for Mid Face Soft Tissue Augmentation in Adult Participants

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2022-09-02
Completion:: 2025-05-08

Conditions

Mid Face Volume Deficit

Interventions

DEVICE

No Results Yet

NCT05440812 | COMPLETED | NA

36 participants

Improving Personal Recovery After Depression With a Blended Module (STAIRS)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2022-10-11
Completion:: 2025-05-17

Conditions

Depression

Interventions

BEHAVIORAL

No Results Yet

NCT05440617 | RECRUITING

100 participants

Biorepository in Participants Who Undergo OTC for Gonadotoxic Therapy

Study Type:: OBSERVATIONAL
Last Updated:: 2026-06-01
Start Date:: 2022-07-22
Completion:: 2041-09-21

Conditions

Acute Ovarian Failure
Infertility
Early Menopause And Infertility In Females After Treatment For Childhood Cancer

No Results Yet

NCT05437406 | ACTIVE_NOT_RECRUITING | NA

167 participants

Family, Responsibility, Education, Support, and Health for Latino Caregivers (FRESH-LC)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2022-09-08
Completion:: 2026-10-31

Conditions

Childhood Obesity
Minority Health

Interventions

BEHAVIORAL

No Results Yet

NCT05434689 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

80 participants

COMbination Regimens in MM Post AHCT to elimiNate MRD Utilizing IbERdomide

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2023-01-18
Completion:: 2028-08-31

Conditions

Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT05432791 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

74 participants

Testing Olaparib and Temozolomide Versus the Usual Treatment for Uterine Leiomyosarcoma After Chemotherapy Has Stopped Working

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2023-03-30
Completion:: 2024-08-13

Conditions

Locally Advanced Uterine Corpus Leiomyosarcoma
Metastatic Uterine Corpus Leiomyosarcoma
Stage III Uterine Corpus Leiomyosarcoma AJCC v8
Stage IV Uterine Corpus Leiomyosarcoma AJCC v8
Unresectable Uterine Corpus Leiomyosarcoma

Interventions

PROCEDURE
DRUG

Results Available

NCT05429099 | RECRUITING | NA

420 participants

Mandibular Reconstruction Preplanning (ViPMR)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2022-10-15
Completion:: 2027-10-15

Conditions

Oral Cavity Cancer
Oral Cancer

Interventions

PROCEDURE

No Results Yet

NCT05424198 | ACTIVE_NOT_RECRUITING | NA

80 participants

Trident Multi-tined Cannula for Cervical MBRFA Compared to the Conventional Cannula

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2023-04-26
Completion:: 2026-06-30

Conditions

Cervical Pain
Cervical Facet Joint Pain

Interventions

PROCEDURE

No Results Yet

NCT05419024 | RECRUITING | PHASE2

50 participants

Imaging and Biopsy of People With HIV-1 Undergoing Analytic Treatment Interruption

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2023-01-09
Completion:: 2026-08-01

Conditions

HIV

Interventions

OTHER

No Results Yet

NCT05412290 | ACTIVE_NOT_RECRUITING | PHASE1

9 participants

Mosunetuzumab Consolidation Therapy After autoSCT in r/r Aggressive B Cell Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2022-12-22
Completion:: 2027-01-31

Conditions

B Cell Lymphoma
Aggressive Lymphoma
Diffuse Large B Cell Lymphoma
High-grade B-cell Lymphoma
Transformed Lymphoma
Follicular Lymphoma Grade 3

Interventions

DRUG

No Results Yet

NCT05411718 | RECRUITING | PHASE2

40 participants

A Phase IIa Randomized, Double-Blinded Clinical Trial of Naproxen or Aspirin for Cancer Immune Interception in Lynch Syndrome

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2023-03-21
Completion:: 2026-11-30

Conditions

T Cells
Colorectal Cancer
Lynch Syndrome

Interventions

DRUG

No Results Yet

NCT05402813 | RECRUITING

180 participants

Natural History in Children up to 16 Years With Mild to Profound Hearing Loss Due to Mutations in GJB2 / OTOF Genes

Study Type:: OBSERVATIONAL
Last Updated:: 2026-06-01
Start Date:: 2022-11-18
Completion:: 2031-06-30

Conditions

Sensorineural Hearing Loss, Bilateral
AUNB1
DFNB1A
Congenital Deafness
DFNB9
OTOF Gene Mutation
GJB2 Gene Mutation

Interventions

OTHER

No Results Yet

NCT05389423 | RECRUITING | PHASE1

25 participants

Pomalidomide and Dose-Adjusted EPOCH +/- Rituximab for HIV-Associated Lymphomas

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2023-06-27
Completion:: 2028-06-01

Conditions

Diffuse Large Cell Lymphoma
Non-Hodgkin Lymphoma
Burkitt Lymphoma
Plasmablastic Lymphoma
B-Cell Neoplasm

Interventions

DRUG

No Results Yet

NCT05377684 | ACTIVE_NOT_RECRUITING

450 participants

Study of Quality of Life and Hormone Levels in Premenopausal Participants With Early Breast Cancer Receiving Triptorelin Plus Additional Cancer Treatment

Study Type:: OBSERVATIONAL
Last Updated:: 2026-06-01
Start Date:: 2022-06-09
Completion:: 2026-06-05

Conditions

Early-stage Breast Cancer

No Results Yet

NCT05375812 | RECRUITING

85 participants

NIH Investigative Deep Phenotyping Study of Gulf War Veteran Health (Project NIH IN-DEPTH)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-06-01
Start Date:: 2023-04-16
Completion:: 2030-12-31

Conditions

Gulf War Illness

No Results Yet

NCT05372627 | NOT_YET_RECRUITING

1000 participants

NHLBI-Emory Advanced Cardiac CT Reconstruction

Study Type:: OBSERVATIONAL
Last Updated:: 2026-06-01
Start Date:: 2026-06-04
Completion:: 2031-01-30

Conditions

Structural Heart Disease

No Results Yet

NCT05369429 | RECRUITING | NA

6516 participants

My Wellbeing Guide: A Novel Tool for Managing Stress and Improving Quality of Life

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2022-12-02
Completion:: 2028-07-05

Conditions

Cancer
Anxiety
Depressive Symptoms

Interventions

BEHAVIORAL

No Results Yet

NCT05367440 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

174 participants

Study of AZD5305 When Given in Combination With New Hormonal Agents in Patients With Metastatic Prostate Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2022-06-02
Completion:: 2031-04-11

Conditions

Metastatic Prostate Cancer

Interventions

DRUG

No Results Yet

NCT05364879 | RECRUITING | NA

108 participants

Prehabilitation for Ovarian Cancer Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2023-01-03
Completion:: 2027-08-31

Conditions

Prehabilitation
Exercise
Frailty
Ovarian Cancer
Surgical Complication
Treatment Outcomes
Enhanced Recovery After Surgery

Interventions

BEHAVIORAL

No Results Yet

NCT05364554 | COMPLETED | PHASE2

227 participants

A Long-term Extension Study of JNJ-77242113 in Participants With Moderate-to-Severe Plaque Psoriasis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2022-06-10
Completion:: 2023-09-29

Conditions

Plaque Psoriasis

Interventions

DRUG

Results Available

NCT05363267 | ACTIVE_NOT_RECRUITING | PHASE1

23 participants

NF-1, Nutraceutical Intervention

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2022-07-06
Completion:: 2025-09-02

Conditions

Neurofibromatosis 1

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT05361434 | COMPLETED

311 participants

A Study of the Effectiveness of Cabozantinib in Combination With Nivolumab as First-line Treatment of Advanced Renal Cell Carcinoma (aRCC) in Adults

Study Type:: OBSERVATIONAL
Last Updated:: 2026-06-01
Start Date:: 2022-09-26
Completion:: 2025-10-20

Conditions

Advanced Renal Cell Carcinoma

No Results Yet

NCT05360446 | ACTIVE_NOT_RECRUITING | PHASE3

608 participants

Coronary Computed Tomography Study to Assess the Effect of Inclisiran in Addition to Maximally Tolerated Statin Therapy on Atherosclerotic Plaque Progression in Participants With a Diagnosis of Non-obstructive Coronary Artery Disease Without Previous Cardiovascular Events

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2022-07-08
Completion:: 2026-10-26

Conditions

Coronary Artery Disease

Interventions

DRUG

No Results Yet

NCT05344469 | RECRUITING

800 participants

A NIS Evaluating Various Injectable and Oral Treatments in Patients With Relapsing Multiple Sclerosis

Study Type:: OBSERVATIONAL
Last Updated:: 2026-06-01
Start Date:: 2022-05-10
Completion:: 2029-05-30

Conditions

Relapsing Multiple Sclerosis

Interventions

OTHER

No Results Yet

NCT05337553 | ACTIVE_NOT_RECRUITING | PHASE3

269 participants

A Study to Evaluate the Efficacy and Safety of Taldefgrobep Alfa in Participants With Spinal Muscular Atrophy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2022-07-06
Completion:: 2024-09-25

Conditions

Spinal Muscular Atrophy
Neuromuscular Diseases
SMA

Interventions

DRUG

No Results Yet

NCT05333978 | TERMINATED | NA

29 participants

Optoacoustic Detection of Inflammation Using MSOT Device

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2022-05-31
Completion:: 2026-04-20

Conditions

Graft Vs Host Disease
Colitis
Crohn Disease

Interventions

DEVICE
PROCEDURE

No Results Yet

NCT05330520 | ACTIVE_NOT_RECRUITING | NA

60 participants

Long Term Safety and Efficacy of Butterfly Medical Prostatic Retraction Device in Benign Prostatic Hyperplasia (BPH) Patients Who Completed 12 Months of Follow-Up Post Implantation (Continuation Study for Study BM-011-IL)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2021-02-10
Completion:: 2027-02-01

Conditions

BPH
BOO - Bladder Outflow Obstruction
Enlarged Prostate (BPH)

Interventions

PROCEDURE

No Results Yet

NCT05329766 | ACTIVE_NOT_RECRUITING | PHASE2

332 participants

A Safety and Efficacy Study of Treatment Combinations With and Without Chemotherapy in Adult Participants With Advanced Upper Gastrointestinal Tract Malignancies

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2022-06-10
Completion:: 2027-01-31

Conditions

Gastrointestinal Tract Malignancies

Interventions

DRUG

No Results Yet

NCT05312840 | COMPLETED | PHASE4

20 participants

Efficacy and Safety of Conventional and Low-dose Platinum Gemcitabine Combined With Sintilimab With Delayed Administration in First-line Treatment of Advanced Squamous Non-small Cell Lung Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2022-01-01
Completion:: 2024-12-31

Conditions

Non Small Cell Lung Cancer

Interventions

DRUG

No Results Yet