MedTrace Logo

Natural History in Children up to 16 Years With Mild to Profound Hearing Loss Due to Mutations in GJB2 / OTOF Genes

NCT05402813 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 180

Last updated 2026-04-06

No results posted yet for this study

Summary

The purpose of this study is to follow the natural history of non-syndromic hearing loss caused by mutations in two genes (GJB2 or OTOF) in children up to 16 years of age.

Conditions

  • Sensorineural Hearing Loss, Bilateral
  • AUNB1
  • DFNB1A
  • Congenital Deafness
  • DFNB9
  • OTOF Gene Mutation
  • GJB2 Gene Mutation

Interventions

OTHER

Pure Tone Audiometry Assessment

Collection of Pure Tone Audiometry data performed in routine practice during study period

OTHER

Quality of Life Questionnaires

Collection of Quality of Life questionnaire's answers during study period

Sponsors & Collaborators

  • Sensorion

    lead INDUSTRY

Principal Investigators

  • Natalie LOUNDON, MD · Necker Hospital

Eligibility

Max Age
16 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-11-18
Primary Completion
2028-11-18
Completion
2028-11-18

Countries

  • France

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05402813 on ClinicalTrials.gov