Clinical Trials

NCT04315701 | ACTIVE_NOT_RECRUITING | PHASE2

35 participants

A PD-1 Checkpoint Inhibitor (Cemiplimab) for High-Risk Localized, Locally Recurrent, or Regionally Advanced Skin Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2020-06-17
Completion:: 2026-12-31

Conditions

Recurrent Skin Squamous Cell Carcinoma
Resectable Skin Squamous Cell Carcinoma
Stage I Skin Cancer
Stage II Skin Cancer
Stage III Skin Cancer

Interventions

BIOLOGICAL
PROCEDURE

No Results Yet

NCT04307667 | RECRUITING

50 participants

Microglia Activation in Asthma

Study Type:: OBSERVATIONAL
Last Updated:: 2026-06-01
Start Date:: 2019-12-17
Completion:: 2028-08-01

Conditions

Asthma

Interventions

BIOLOGICAL
RADIATION

No Results Yet

NCT04305431 | RECRUITING | NA

55 participants

Dietary Behavior Intervention in African Americans at Risk for Cardiovascular Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2021-02-25
Completion:: 2026-12-19

Conditions

Diet
Cooking

Interventions

BEHAVIORAL

No Results Yet

NCT04303117 | RECRUITING | PHASE1/PHASE2

80 participants

PDS01ADC Monotherapy and in Combination With M7824 in Advanced Kaposi Sarcoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2020-07-13
Completion:: 2028-12-01

Conditions

Kaposi Sarcoma

Interventions

DRUG

No Results Yet

NCT04297683 | RECRUITING | PHASE2/PHASE3

1500 participants

HEALEY ALS Platform Trial - Master Protocol

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2020-06-14
Completion:: 2027-07-31

Conditions

Amyotrophic Lateral Sclerosis

Interventions

DRUG

No Results Yet

NCT04287647 | TERMINATED | NA

8 participants

Transpyloric Stenting as a Predictor for G-POEM for Refractory Gastroparesis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2019-05-15
Completion:: 2026-05-27

Conditions

Gastroparesis

Interventions

DEVICE
OTHER

No Results Yet

NCT04284787 | ACTIVE_NOT_RECRUITING | PHASE2

60 participants

BLAST MRD AML-2: BLockade of PD-1 Added to Standard Therapy to Target Measurable Residual Disease in Acute Myeloid Leukemia 2- A Randomized Phase 2 Study of Anti-PD-1 Pembrolizumab in Combination With Azacitidine and Venetoclax as Frontline Therapy in Unfit Patients With Acute Myeloid Leukemia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2021-02-16
Completion:: 2023-06-05

Conditions

Acute Myeloid Leukemia
Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome
Acute Myeloid Leukemia Post Cytotoxic Therapy
Secondary Acute Myeloid Leukemia

Interventions

DRUG
PROCEDURE
BIOLOGICAL

Results Available

NCT04272684 | COMPLETED | NA

40 participants

On the Road to Recovery After Critical Illness

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2020-02-26
Completion:: 2024-09-30

Conditions

Post Intensive Care Syndrome

Interventions

OTHER

No Results Yet

NCT04269200 | ACTIVE_NOT_RECRUITING | PHASE3

805 participants

Durvalumab With or Without Olaparib as Maintenance Therapy After First-Line Treatment of Advanced and Recurrent Endometrial Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2020-05-05
Completion:: 2024-07-08

Conditions

Endometrial Neoplasms

Interventions

DRUG
BIOLOGICAL

Results Available

NCT04267302 | ACTIVE_NOT_RECRUITING | NA

100 participants

Baby Item Learning and Development Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2020-02-07
Completion:: 2023-05-31

Conditions

Infant Development

Interventions

OTHER

No Results Yet

NCT04250051 | TERMINATED | PHASE1

2 participants

Ivosidenib and Combination Chemotherapy for the Treatment of IDH1 Mutant Relapsed or Refractory Acute Myeloid Leukemia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2020-12-21
Completion:: 2022-01-16

Conditions

Recurrent Acute Myeloid Leukemia
Recurrent Myelodysplastic Syndrome
Recurrent Myeloproliferative Neoplasm
Refractory Acute Myeloid Leukemia
Refractory Myelodysplastic Syndrome
Newly Diagnosed Acute Myeloid Leukemia (AML)
IDH1 Mutation Myeloid Neoplasms
Acute Myeloid Leukemia (AML)

Interventions

DRUG
BIOLOGICAL

No Results Yet

NCT04234568 | ACTIVE_NOT_RECRUITING | PHASE1

31 participants

Testing the Addition of an Anti-cancer Drug, Triapine, to the Usual Radiation-Based Treatment (Lutetium Lu 177 Dotatate) for Neuroendocrine Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2020-07-20
Completion:: 2024-09-17

Conditions

Metastatic Digestive System Neuroendocrine Neoplasm
Metastatic Neuroendocrine Tumor

Interventions

PROCEDURE
DRUG

Results Available

NCT04227379 | COMPLETED | NA

366 participants

Diabetes Disparities: Texting to Extend Treatment (DD-TXT)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2023-01-30
Completion:: 2025-04-30

Conditions

Diabetes Mellitus, Type 2

Interventions

BEHAVIORAL

Results Available

NCT04224493 | ACTIVE_NOT_RECRUITING | PHASE3

599 participants

A Study to Assess the Efficacy, Safety, Pharmacodynamics, and Pharmacokinetics of Tazemetostat in Combination With Lenalidomide Plus Rituximab Versus Placebo in Combination With Lenalidomide Plus Rituximab in Adult Patients at Least 18 Years of Age With Relapsed/Refractory Follicular Lymphoma.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2020-06-11
Completion:: 2027-02-13

Conditions

Relapsed/Refractory Follicular Lymphoma
Follicular Lymphoma
Refractory Follicular Lymphoma

Interventions

DRUG
COMBINATION_PRODUCT

No Results Yet

NCT04222309 | SUSPENDED | PHASE1

10 participants

Laparoscopically Harvested Omental Free Tissue Autograft to Bypass the Blood Brain Barrier (BBB) in Human Recurrent Glioblastoma Multiforme (rGBM)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2020-01-06
Completion:: 2027-01-31

Conditions

Glioma
Glioma, Malignant
Glioblastoma
Glioblastoma Multiforme
Glioblastoma Multiforme of Brain
GBM
Brain Cancer

Interventions

PROCEDURE

No Results Yet

NCT04216342 | RECRUITING | PHASE1

64 participants

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Fx-5A in Healthy Volunteers

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2021-09-29
Completion:: 2026-06-30

Conditions

Cardiovascular Disease

Interventions

BIOLOGICAL

No Results Yet

NCT04198857 | COMPLETED | NA

214 participants

Development and Testing of a Mobile Health Application for Management of Gestational Diabetes

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2021-10-18
Completion:: 2026-04-06

Conditions

Diabetes, Gestational
Telemedicine

Interventions

BEHAVIORAL

No Results Yet

NCT04195347 | RECRUITING | PHASE1/PHASE2

42 participants

Study of CM4620 to Reduce the Severity of Pancreatitis Due to Asparaginase

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2020-09-04
Completion:: 2027-01-31

Conditions

Acute Pancreatitis

Interventions

DRUG

No Results Yet

NCT04168528 | TERMINATED | PHASE1/PHASE2

13 participants

Phase I/IIa Study of 68GaNOTA-Anti-MMR-VHH2 for PET/CT

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2019-11-05
Completion:: 2024-12-04

Conditions

Malignant Solid Tumor
Breast Cancer
Melanoma (Skin)

Interventions

DRUG

No Results Yet

NCT04164472 | COMPLETED | NA

5250 participants

NIH R01 Friend to Friend With Coaching

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2019-11-12
Completion:: 2025-06-30

Conditions

Aggression

Interventions

BEHAVIORAL

No Results Yet

NCT04139616 | RECRUITING

2000 participants

Prospective Validation of a Pre-Specified Algorithm for the Management of Conduction Disturbances Following TAVR

Study Type:: OBSERVATIONAL
Last Updated:: 2026-06-01
Start Date:: 2020-02-25
Completion:: 2025-12-25

Conditions

Conduction Disturbances
Transcatheter Aortic Valve Replacement
Permanent Pacemaker Implantation

No Results Yet

NCT04139304 | RECRUITING | EARLY_PHASE1

15 participants

A Study of Daratumumab and Dose-Adjusted EPOCH in Plasmablastic Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2021-05-24
Completion:: 2029-07-31

Conditions

Plasmablastic Lymphoma
Ann Arbor Stage I Diffuse Large B-Cell Lymphoma
Ann Arbor Stage II Diffuse Large B-Cell Lymphoma
Ann Arbor Stage III Diffuse Large B-Cell Lymphoma
Ann Arbor Stage IV Diffuse Large B-Cell Lymphoma

Interventions

DRUG
BIOLOGICAL

No Results Yet

NCT04129905 | COMPLETED | NA

40 participants

Assessment of the Relations Between Endothelial and Venous Dysfunctions and Left Ventricular Obstruction in Genetic Hypertrophic Cardiomyopathies

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2019-10-22
Completion:: 2021-12-14

Conditions

Hypertrophic Cardiomyopathy
Endothelial Dysfunction

Interventions

DIAGNOSTIC_TEST
BIOLOGICAL

No Results Yet

NCT04123535 | TERMINATED | NA

5 participants

Focused Ultrasound to Promote Immune Responses for Undifferentiated Pleomorphic Sarcoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2020-01-23
Completion:: 2026-04-30

Conditions

Undifferentiated Pleomorphic Sarcoma

Interventions

DEVICE

No Results Yet

NCT04109729 | ACTIVE_NOT_RECRUITING | PHASE1

39 participants

Study of Nivolumab in Combination w Radium-223 in Men w Metastatic Castration Resistant Prostate Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2020-09-16
Completion:: 2026-04-28

Conditions

Metastatic Castration-resistant Prostate Cancer

Interventions

DRUG

No Results Yet

NCT04106349 | ACTIVE_NOT_RECRUITING

150 participants

Observational Real-life Study of Cabozantinib in Monotherapy or in Combination With Nivolumab in Advanced Renal Cell Carcinoma (RCC)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-06-01
Start Date:: 2020-03-03
Completion:: 2027-03-31

Conditions

Advanced or Metastatic Renal Cell Carcinoma

No Results Yet

NCT04095026 | ENROLLING_BY_INVITATION

200 participants

Study of Direct Brain Recording and Stimulation for Memory Enhancement

Study Type:: OBSERVATIONAL
Last Updated:: 2026-06-01
Start Date:: 2016-10-28
Completion:: 2027-01-01

Conditions

Epilepsy

No Results Yet

NCT04089059 | ACTIVE_NOT_RECRUITING | NA

738 participants

PROACTIVE-HF IDE Trial Heart Failure NYHA Class III

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2020-01-10
Completion:: 2028-04-30

Conditions

Heart Failure NYHA Class III

Interventions

DEVICE

Results Available

NCT04080232 | COMPLETED | NA

16 participants

Study of Pulmonary MRI for the Diagnosis of Bronchiolitis Obliterans Syndrome After Allogeneic Stem Cell Transplantation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2020-02-06
Completion:: 2023-05-11

Conditions

Bronchiolitis Obliterans

Interventions

DEVICE

No Results Yet

NCT04070027 | ACTIVE_NOT_RECRUITING | NA

109 participants

Progressive Resistance Training Versus Total Hip Arthroplasty in Patients With Hip Osteoarthritis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2019-09-02
Completion:: 2022-05-05

Conditions

Hip Osteoarthritis

Interventions

PROCEDURE
OTHER

No Results Yet

NCT04069312 | COMPLETED | PHASE4

1032 participants

Roflumilast or Azithromycin to Prevent COPD Exacerbations (RELIANCE)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2020-02-11
Completion:: 2026-03-01

Conditions

Chronic Obstructive Pulmonary Disease Severe
Chronic Bronchitis

Interventions

DRUG

No Results Yet

NCT04044495 | COMPLETED | NA

47 participants

Sleep, Rhythms and Risk of Alzheimer's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2019-09-09
Completion:: 2022-02-22

Conditions

Alzheimer Disease
Sleep

Interventions

OTHER

No Results Yet

NCT04043052 | COMPLETED | NA

401 participants

Mobile Technologies and Post-stroke Depression

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2020-09-09
Completion:: 2024-09-26

Conditions

Stroke
Depression

Interventions

OTHER
BIOLOGICAL

No Results Yet

NCT04014231 | COMPLETED

159 participants

Novel Single Wave Assessment in Measuring Cardiac Dysfunction and Metabolic Syndrome in Patients With Cancer

Study Type:: OBSERVATIONAL
Last Updated:: 2026-06-01
Start Date:: 2017-07-21
Completion:: 2026-04-20

Conditions

Malignant Neoplasm

Interventions

PROCEDURE
OTHER

No Results Yet

NCT04012944 | ACTIVE_NOT_RECRUITING | NA

81 participants

SIRONA 2 Trial Heart Failure NYHA Class III

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2019-06-26
Completion:: 2021-10-30

Conditions

Heart Failure NYHA Class III

Interventions

DEVICE

No Results Yet

NCT04009499 | COMPLETED | PHASE3

1131 participants

A Study to Assess the Long-term Safety, Tolerability, and Efficacy of Bimekizumab in the Treatment of Subjects With Active Psoriatic Arthritis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2019-08-13
Completion:: 2026-05-26

Conditions

Psoriatic Arthritis

Interventions

DRUG

No Results Yet

NCT04002947 | RECRUITING | PHASE2

132 participants

Acalabrutinib With DA-EPOCH-R or R-CHOP for People With Untreated Diffuse Large B-cell Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2019-08-05
Completion:: 2026-05-31

Conditions

Non-Hodgkin's Lymphoma
Diffuse Large B-Cell Lymphoma
DLBCL
NHL

Interventions

DRUG
BIOLOGICAL

No Results Yet

NCT03955627 | COMPLETED | NA

12 participants

REJOIN Trial for Older Breast Cancer Survivors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2021-06-15
Completion:: 2025-07-29

Conditions

Breast Cancer Female

Interventions

BEHAVIORAL

No Results Yet

NCT03953898 | ACTIVE_NOT_RECRUITING | PHASE2

14 participants

Using the Anticancer Drug Olaparib to Treat Relapsed/Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome With an Isocitrate Dehydrogenase (IDH) Mutation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2020-08-04
Completion:: 2024-01-16

Conditions

Acute Myeloid Leukemia
Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome
Acute Myeloid Leukemia Post Cytotoxic Therapy
Recurrent Acute Myeloid Leukemia
Recurrent Myelodysplastic Syndrome
Refractory Acute Myeloid Leukemia
Refractory Myelodysplastic Syndrome

Interventions

PROCEDURE
DRUG

Results Available

NCT03952585 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

384 participants

De-intensified Radiation Therapy With Chemotherapy (Cisplatin) or Immunotherapy (Nivolumab) in Treating Patients With Early-Stage, HPV-Positive, Non-Smoking Associated Oropharyngeal Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2019-10-09
Completion:: 2024-03-01

Conditions

Basaloid Squamous Cell Carcinoma
Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
Oropharyngeal Squamous Cell Carcinoma
Papillary Squamous Cell Carcinoma
Pathologic Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
Pathologic Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
Squamous Cell Carcinoma

Interventions

OTHER
RADIATION
PROCEDURE
BIOLOGICAL
DRUG

Results Available