Clinical Trials

NCT02390752 | RECRUITING | PHASE1
54 participants

Phase I Trial of TURALIO(R) (Pexidartinib, PLX3397) in Children and Young Adults With Refractory Leukemias and Refractory Solid Tumors Including Neurofibromatosis Type 1 (NF1) Associated Plexiform Neurofibromas (PN) and Tenosynovial Giant Cell Tumor ...

Study Type:
INTERVENTIONAL
Last Updated:
2026-06-01
Start Date:
2015-04-29
Completion:
2026-12-31
Conditions
  • Neurofibroma, Plexiform
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma
  • Leukemia, Promyelocytic, Acute
  • Sarcoma
Interventions
  • DRUG
No Results Yet
NCT02220985 | COMPLETED | PHASE2
84 participants

Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts From HLA-Matched Related and Unrelated Donors in Preventing GVHD

Study Type:
INTERVENTIONAL
Last Updated:
2026-06-01
Start Date:
2015-03-23
Completion:
2025-04-01
Conditions
  • Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive
  • Acute Biphenotypic Leukemia
  • Acute Leukemia of Ambiguous Lineage
  • Acute Undifferentiated Leukemia
  • Allogeneic Hematopoietic Stem Cell Transplant Recipient
  • Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive
  • Blastic Plasmacytoid Dendritic Cell Neoplasm
  • Childhood Acute Lymphoblastic Leukemia in Remission
  • Childhood Acute Myeloid Leukemia in Remission
  • Donor
  • Lymphoblastic Lymphoma
  • Myelodysplastic Syndrome With Excess Blasts
  • Myelodysplastic Syndrome With Excess Blasts-1
  • Myelodysplastic Syndrome With Excess Blasts-2
  • Recurrent Acute Lymphoblastic Leukemia
  • Recurrent Acute Myeloid Leukemia
  • Recurrent Childhood Acute Lymphoblastic Leukemia
  • Recurrent Childhood Acute Myeloid Leukemia
  • Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive
  • Refractory Acute Lymphoblastic Leukemia
  • Refractory Acute Myeloid Leukemia
  • Acute Lymphoblastic Leukemia in Remission
  • Acute Myeloid Leukemia in Remission
Interventions
  • PROCEDURE
  • DRUG
  • OTHER
  • RADIATION
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